Effects of combined inoculation of arbuscular mycorrhizal fungi and plant growth-promoting rhizosphere bacteria on seedling growth and rhizosphere microecology by Wanli Zeng, Dan Xiang, Xuemei Li, Qian Gao, Yudong Chen, Kunmiao Wang, Yingying Qian, Luoping Wang, Jing Li, Qili Mi, Haitao Huang, Li Xu, Mingfang Zhao, Yingzhen Zhang, Haiying Xiang

“…Furthermore, the A_SG29 treatment yielded the highest diversity indexes and largest percentages of significantly enriched bacterial taxa, and significantly promoted the colonization of AMF in tobacco roots and Pseudomonas in rhizosphere soil. Differential metabolic-pathway predictions using PICRUSt2 showed that the A_SG29 treatment significantly increased the metabolic pathway richness of tobacco rhizosphere microorganisms, and significantly up-regulated some metabolic pathways that may benefit plant growth. …”
Get full text

Bone-spicule pattern in retinitis pigmentosa by Krzysztof Eder, Rafał Leszczyński, Ewa Mrukwa-Kominek, Paulina Langosz, Sebastian Sirek

“…The occurrence of the disease is not due to damage in a single metabolic pathway. Rather, it is a multifactorial pathophysiological process involving the failure of various cellular regulatory mechanisms and the presence of histopathological changes. …”
Get full text

The Association between Polymorphisms of Vitamin D Metabolic-Related Genes and Vitamin D3 Supplementation in Type 2 Diabetic Patients by Zhiyong Hu, ShaSha Tao, Huaqing Liu, Guotao Pan, Bingyan Li, Zengli Zhang

“…To investigate the effect of single nucleotide polymorphisms (SNPs) of the key genes in vitamin D metabolic pathway on the serum 25(OH)D level after long-term vitamin D3 supplementation and provide a theoretical basis for rational vitamin D3 supplementation in diabetic patients with different genetic backgrounds. …”
Get full text

The biological functions of sphingolipids in plant pathogenic fungi. by Xue-Ming Zhu, Lin Li, Jian-Dong Bao, Jiao-Yu Wang, Asen Daskalov, Xiao-Hong Liu, Maurizio Del Poeta, Fu-Cheng Lin

“…However, our knowledge on the metabolism and function of the sphingolipid metabolic pathway of pathogenic fungi affecting plants is still very limited. …”
Get full text

Research Progress in Natural Sources, Biosynthesis and Metabolism Regulation of Rutin in Plant-Derived Food Materials by ZHOU Ting, WANG Haige, ZHANG Jixing, BAO Yingcai, YU Yongli, CHANG Jie

“…Rutin, a flavanol glycoside derived from quercetin, is classified as a secondary metabolite from the phenylpropane metabolic pathway in higher plants. It possesses various pharmacological and physiological activities, including antioxidant, anti-aging, anti-inflammatory, anti-diabetic, and anti-cancer properties. …”
Get full text

Analysis of glutamate-dependent mechanism and optimization of fermentation conditions for poly-gamma-glutamic acid production by Bacillus subtilis SCP017-03. by Caiyun Wu, Yutao Gou, Shuai Jing, Wei Li, Fanglan Ge, Jiao Li, Yao Ren

“…The introduction of glutamate substantially altered gene expression within the central metabolic pathway of cellular carbon. Most genes in the pentose phosphate pathway (PPP), tricarboxylic acid (TCA) cycle, and energy-consuming phase of the glycolysis pathway (EMP) were down-regulated, whereas those in the energy-producing phase of glycolysis and those responsible for γ-PGA synthesis were up-regulated. …”
Get full text

Pluripotent Stem Cell Metabolism and Mitochondria: Beyond ATP by Jarmon G. Lees, David K. Gardner, Alexandra J. Harvey

“…The significance of altered nutrient availability, particularly oxygen, and metabolic pathway activity has been highlighted by extensive studies of their impact on preimplantation embryo development, physiology, and viability. …”
Get full text

Effect of Microbial Community Succession on Tyrosine Metabolism during Soybean Paste Fermentation by JIN Manqin, LUO Dan, WANG Gangtu, LI Yixin, PEI Wei, XUE Wentong

“…To find an effective method for eliminating white spots on the surface of soybean paste and enhancing its quality, this study analyzed the relationship between microbial community succession and physicochemical properties and the tyrosine metabolic pathway throughout the entire production cycle of soybean paste. …”
Get full text

Peningkatan akumulasi tiamin pada kultur Escherichia coli melalui peningkatan oksigenasi dan penghilangan rpoS by Nuraliah Rusman, Prayoga Suryadarma, Nisa Rachmania Mubarik

“…Thiamine diphosphate is one of the coenzymes that are commonly found in the metabolic pathways of microbial cells. Increasing the thiamine formation pathway as a precursor in the thiamine metabolic pathway is a strategy in this study. …”
Get full text

Asymmetric Dimethyl Arginine as a Biomarker of Atherosclerosis in Rheumatoid Arthritis by Manuela Di Franco, Bruno Lucchino, Fabrizio Conti, Guido Valesini, Francesca Romana Spinelli

“…Asymmetric dimethylarginine is gaining attention for its implication in the pathogenesis of endothelial dysfunction and as biomarkers of subclinical atherosclerosis. Moreover, the metabolic pathway of methylarginines offers possible targets for therapeutic interventions to decrease the cardiovascular risk. …”
Get full text

Assessing the effect of foodborne endocrine disruptors exposure on methionine synthase activity in neuro-2a neuroblastoma cell lines by Gabriela García-Cerón, Alba Fernanda Solano-González, Iván Hazael Bello-Cortés, Ileana Andrea Bonilla-Brunner, Daniela Araiza-Olivera, Manuel Gutiérrez-Aguilar, Yazmin Ramiro-Cortés, Marcos Francisco Rosetti, Roeb García-Arrazola

“…MS is the key enzyme in the metabolic pathway that has been proposed elsewhere to be related to redox/methylation related disorders.…”
Get full text

Analysis of the spatial distribution of metabolites in Aloe vera leaves by mass spectrometry imaging and UHPLC-UHRMS by Sumi Krupa, Tomasz Ruman, Wiktoria Szuberla, Joanna Nizioł

“…Analysis of the results of mass spectrometry imaging provided information about the potential changes in metabolic pathway expression in different regions of the leaf.…”
Get full text

Comparative metabolomics reveals eggshell translucency formation using LC-MS Analysis by Ying Ma, Zhonghua Ning

“…The results showed that we identified two essential metabolic pathways through differential metabolite pathway analysis, which were glycine, serine, and threonine metabolism related to amino acids metabolism and the PPAR metabolic pathway related to lipid metabolism. …”
Get full text

The impact of glycolysis on ischemic stroke: from molecular mechanisms to clinical applications by Yingquan Liu, Peijia Hu, Hongliang Cheng, Fangyuan Xu, Yu Ye

“…Glycolysis, a central metabolic pathway, plays a critical role in bridging the gap between metabolic dysfunction and neurological impairment. …”
Get full text

The comparative gene expression concern to the seed pigmentation in maize ( L.) by Kyu Jin Sa, Ik-Young Choi, Ju Kyong Lee

“…Additionally, 37 genes were detected in the metabolic pathway concern to the seed pigmentation by BINs analysis using MAPMAN software. …”
Get full text

The emerging role of 12/15-lipoxygenase in ischemic stroke by Xuening Wang, Qiuji Shao, Yuan Gao

“…The arachidonic acid metabolic pathway is a classic inflammatory pathway. 12/15-lipoxygenase (LOX), a member of the lipoxygenase family that metabolizes arachidonic acid, has been implicated in the pathogenesis of numerous central nervous system (CNS) diseases. …”
Get full text

Amino acid stable carbon isotopes in nail keratin illuminate breastfeeding and weaning practices of mother – infant dyads by Hana Salahuddin, Andrea L. Waters-Rist, Fred J. Longstaffe

“…We propose that glycine’s ‘conditionally essential’ metabolic pathway during infancy allows it to reflect maternal glycine δ 13C, indicating breastmilk consumption. …”
Get full text

PPARs, Cardiovascular Metabolism, and Function: Near- or Far-from-Equilibrium Pathways by Yves Lecarpentier, Victor Claes, Jean-Louis Hébert

“…Moreover, PPARs are directly or indirectly involved in cellular oscillatory processes such as the Wnt-b-catenin pathway, circadian rhythms of arterial blood pressure and cardiac frequency and glycolysis metabolic pathway. Dysfunction of clock genes and PPARγ may lead to hyperphagia, obesity, metabolic syndrome, myocardial infarction and sudden cardiac death, In pathological conditions, regulatory processes of the cardiovascular system may bifurcate towards new states, such as those encountered in hypertension, type 2 diabetes, and heart failure. …”
Get full text

Nitric oxide modulates interleukin-2-induced proliferation in CTLL-2 cells by J. Padrón, L. Glaría, O. Martinez, M. Torres, E. Lopez, R. Delgado, L. Caveda, A. Rojas

“…The role of the L-arginine–nitric oxide metabolic pathway was explored for interleukin-2-induced proliferation in the cytotoxic T lymphocyte clone CTLL-2. …”
Get full text

Diagnosis of Methyl Malonicaciduria from 2013 to 2018 by Alina Concepción Álvarez, Ivette Camayd Viera, Norma Elena de León Ojeda, Alina García García, Laritza Martínez Rey, Daniel Quintana Hernández

“…The excretion of this metabolite may or may not be accompanied by elevated homocysteine levels depending on the affected metabolic pathway. <br /><strong>Objective:</strong> to describe the implementation of a laboratory methodology that combines methylmalonic acid and homocysteine in the differential diagnosis and monitoring of methylmalonic aciduria in the period from 2013 to 2018. …”
Get full text