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281
Diversity of the non-targeted metabolomic data across various varieties of Cloves (Syzygium spp.)Figshare
Published 2025-02-01“…We identified and quantified 427 metabolites across various metabolic pathways. The metabolomics data for all samples are publicly available at the Figshare repository under 10.6084/m9.figshare.27212016. …”
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282
Investigating the neuroprotective effects of Dracocephalum moldavica extract and its effect on metabolomic profile of rat model of sporadic Alzheimer's disease
Published 2025-02-01“…This study aimed to assess the neuroprotective effects of the hydroalcoholic extract of Dracocephalum moldavica (DM) on cognitive impairment, biomarker changes, and putative metabolic pathways in a rat model of AD induced by intracerebroventricular streptozotocin (ICV-STZ). …”
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283
Establishment and maturation of gut microbiota in White King pigeon squabs: role of pigeon milk
Published 2025-01-01“…Functional prediction analysis indicated that the gut microbiota of pigeons primarily participate in metabolic pathways related to carbohydrates, amino acids, lipids, cofactors, and vitamins. …”
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284
The prebiotic potential of dietary onion extracts: shaping gut microbial structures and promoting beneficial metabolites
Published 2025-01-01“…Consistent with the enriched taxa and the predicted metabolic pathways, SCFAs and their related metabolites were significantly enriched in the onion-treated group. …”
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285
Integrated hepatic transcriptomics and metabolomics identify Pck1 as a key factor in the broad dysregulation induced by vehicle pollutants
Published 2024-12-01“…Results DE exposure for 2 weeks dysregulated 658 liver genes overrepresented in whole cell metabolic pathways, especially including lipid and carbohydrate metabolism, and the respiratory electron transport pathway. …”
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286
ANO7 expression in the prostate modulates mitochondrial function and lipid metabolism
Published 2025-02-01“…Conclusions This study provides new insights into the function of ANO7 in prostate cells, highlighting its involvement in metabolic pathways, particularly OXPHOS and lipid metabolism. …”
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287
Effect of Geographic Regions on the Flavor Quality and Non-Volatile Compounds of Chinese Matcha
Published 2025-01-01“…The types of non-volatile flavor differential metabolites of G and H were more numerous than those of Z1 and Z2. The metabolic pathways, biosynthesis of secondary metabolites, biosynthesis of co-factors, flavonoid biosynthesis, biosynthesis of amino acids, biosynthesis of various plant secondary metabolites, and purine metabolism of metabolic pathways were the main KEGG pathways. …”
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288
No rumen fermentation profiles and associated microbial diversities difference were found between Hu sheep and Karakul sheep fed a cottonseed hull diet
Published 2025-01-01“…Metabolomic results revealed that the metabolic pathways in stage I were mainly concentrated in purine metabolism and lipid metabolism, while stage II was dominated by amino acid metabolism. …”
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289
Elucidating the Molecular Mechanisms and Comprehensive Effects of Sludge‐Derived Plant Biostimulants on Crop Growth: Insights from Metabolomic Analysis
Published 2025-01-01“…These results provide a vital foundation for understanding ATH metabolic pathways and advocating for widespread SPB application, offering significant implications for sustainable land management.…”
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290
Extra Fructose in the Growth Medium Fuels Lipogenesis of Adipocytes
Published 2014-01-01“…These adverse outcomes were attributed to its disturbances of key metabolic pathways in the liver. Recently, possible consequences of high fructose levels directly on adipocytes in vivo have been considered. …”
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291
Analysis of fermentation characteristics in fermented grains across seven rounds of sauce-flavored Baijiu: Microbial communities structure, physicochemical parameters, volatile and...
Published 2025-01-01“…Finally, a metabolic network was constructed to predict microbial and flavor compound metabolic pathways. This study provided insights into the fermentation characteristics of SFB from a multi-dimensional perspective.…”
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292
A Systems Biology Overview on Human Diabetic Nephropathy: From Genetic Susceptibility to Post-Transcriptional and Post-Translational Modifications
Published 2016-01-01“…The picture that emerges is complex and fascinating as it includes the regulation/dysregulation of numerous biological processes, converging toward the activation of inflammatory processes, oxidative stress, remodeling of cellular function and morphology, and disturbance of metabolic pathways. The growing interest in the characterization of protein post-translational modifications and the importance of handling large datasets using a systems biology approach are also discussed.…”
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293
The metabolic profiling of Chinese yam fermented by Saccharomyces boulardii and the biological activities of its ethanol extract in vitro
Published 2024-09-01“…Besides, corresponding metabolic pathways analysis initially revealed that the distribution of bioactive substances was concentrated on alcohol-soluble small molecular substances. …”
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294
NAFLD, Estrogens, and Physical Exercise: The Animal Model
Published 2012-01-01“…In recent years, there has been substantial evidence coming mostly from the use of the animal model, that indeed estrogens withdrawal is associated with modifications of molecular markers favouring the activity of metabolic pathways ultimately leading to liver fat accumulation. …”
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295
Metabolic plasticity in pancreatic cancer: The mitochondrial connection
Published 2025-02-01“…Background: Cellular metabolism plays a pivotal role in the development and progression of pancreatic ductal adenocarcinoma (PDAC), with dysregulated metabolic pathways contributing to tumorigenesis and therapeutic resistance. …”
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296
Analysis of differential metabolites in Liuyang douchi at different fermentation stages based on untargeted metabolomics approach
Published 2025-01-01“…Meanwhile, metabolisms related to amino acids were also the main enrichment metabolic pathways. Among them, some flavor compunds such as phenylacetaldehyde might drived from phenylalanine metabolism. …”
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297
The Role of the Microbiota in the Diabetic Peripheral Artery Disease
Published 2019-01-01“…There is an urgency to develop the knowledge of modern medicine about the link between gut microbiota and its host’s metabolic pathways, and it would be useful to understand and justify the interindividual diversity of clinical disease presentation of diabetic vascular complication even if an optimization of pharmacological treatment has been made or in the case of young patients where hypertension, dyslipidemia, and diabetes are not able to justify a very quick progress of atherosclerotic process. …”
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298
Revealing differences in flavor compounds during plum wine fermentation using single and mixed yeast strains through metabolomic analysis
Published 2025-01-01“…The annotation analysis of these compounds revealed 11 important metabolic pathways for proline, aspartate, glutamate, and β-alanine metabolism. …”
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299
Antibacterial mechanism of Lactiplantibacillus plantarum SHY96 cell-free supernatant against Listeria monocytogenes revealed by metabolomics and potential application on chicken br...
Published 2025-01-01“…Metabolomic analysis revealed that LCFS96 significantly altered 450 intracellular metabolites, affecting key metabolic pathways including linoleic acid metabolism, pyrimidine metabolism, purine metabolism, pantothenic acid and CoA biosynthesis, and the TCA cycle. …”
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300
Immunomodulatory effect of efferocytosis at the maternal–fetal interface
Published 2025-01-01“…During efferocytosis, the metabolic pathways of phagocytes are transformed, which, along with the catabolism of apoptotic cargo, can affect their function and inflammatory state. …”
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