Showing 241 - 260 results of 511 for search '"metabolic pathway"', query time: 0.05s Refine Results
  1. 241

    Detection and Characterization of the Metabolites of Ciwujianoside B in Rats Based on UPLC-Fusion Lumos Orbitrap Mass Spectrometry by Wan-Ru Dong, Xue Gao, Chen-Xue Li, Yan Song, Jun-Hong Chai, Jun Liang

    Published 2024-01-01
    “…Finally, ciwujianoside B metabolism and hederasaponin B metabolism were compared, reaching the following conclusions: (i) more than 40 metabolites were identified in both, with the majority of metabolites identified in feces; (ii) the corresponding metabolic pathways in vivo were basically similar, including deglycosylation, acetylation, hydroxylation, glucuronidation, oxidation, and glycosylation; and (iii) deglycosylation was considered the main metabolic reaction, and its metabolites accounted for approximately 50% of all metabolites. …”
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  2. 242

    Metabolomics-based study on the effect of low-voltage electrostatic field treatment on the storage quality of postharvest square bamboo shoots by Xi Wang, Yingchun Mu, Wei Su, Xing Lei, Zuhao Wang, Pulai Zhang

    Published 2025-01-01
    “…These changes were closely related to fatty acid metabolism, TCA cycle, and phenylalanine metabolism pathways. Overall, LP treatment can effectively improve the storage quality of square bamboo shoots.…”
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    Article
  3. 243

    Application of lipidomics in the study of traditional Chinese medicine by Yang Yang, Guangyi Yang, Wenpeng Zhang, Lingyi Xin, Jing Zhu, Hangtian Wang, Baodong Feng, Renyan Liu, Shuya Zhang, Yuanwu Cui, Qinhua Chen, Dean Guo

    Published 2025-02-01
    “…Lipidomics is an emerging discipline that systematically studies the various types, functions, and metabolic pathways of lipids within living organisms. This field compares changes in diseases or drug impact, identifying biomarkers and molecular mechanisms present in lipid metabolic networks across different physiological or pathological states. …”
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    Article
  4. 244

    Regenerative Therapy of Type 1 Diabetes Mellitus: From Pancreatic Islet Transplantation to Mesenchymal Stem Cells by Nadine E. Rekittke, Meidjie Ang, Divya Rawat, Rahul Khatri, Thomas Linn

    Published 2016-01-01
    “…We summarize on what is known about regenerative therapy in type 1 diabetes focusing on pancreatic islet transplantation and new avenues of cell substitution. Metabolic pathways and energy production of transplanted cells are required to be balanced and protection from inflammation in their intravascular bed is desired. …”
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    Article
  5. 245

    Effects of microbial biocontrol agents on tea plantation microecology and tea plant metabolism: a review by Yixin Xie, Yixin Xie, Chunxia Cao, Daye Huang, Yan Gong, Beibei Wang

    Published 2025-01-01
    “…While biotic stress generally has detrimental effects on plants, it also activates defense metabolic pathways, leading to shifts in microbial communities. …”
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  6. 246

    New Cardiovascular and Pulmonary Therapeutic Strategies Based on the Angiotensin-Converting Enzyme 2/Angiotensin-(1–7)/Mas Receptor Axis by Anderson J. Ferreira, Tatiane M. Murça, Rodrigo A. Fraga-Silva, Carlos Henrique Castro, Mohan K. Raizada, Robson A. S. Santos

    Published 2012-01-01
    “…The discovery of the angiotensin-converting enzyme homologue ACE2 revealed important metabolic pathways involved in the Ang-(1–7) synthesis. …”
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  7. 247

    Regenerative therapies for myocardial infarction: exploring the critical role of energy metabolism in achieving cardiac repair by Jiahao Ren, Xinzhe Chen, Tao Wang, Cuiyun Liu, Kun Wang

    Published 2025-02-01
    “…Currently, a large number of studies have focused on changes in metabolic levels before and after the proliferation window of cardiomyocytes, so it is crucial to search for relevant factors in metabolic pathways to regulate the cell cycle in cardiomyocyte progression. …”
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    Article
  8. 248

    Metagenomics approaches for studying the human microbiome by Biniam Moges, Degisew Yinur Mengistu

    Published 2024-12-01
    “…Hence, metagenomics analysis is a powerful advanced technology for comprehensively studying human microbial composition and diversity, exploring novel and antibiotic resistance genes, microbial metabolic pathways, functional dysbiosis, and co-evolution of the microbiome with the host. …”
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    Article
  9. 249

    Metabolomic Analysis of Key Regulatory Metabolites in the Urine of Flavivirus-Infected Mice by Xiaoyan Zheng, Ran Wang

    Published 2022-01-01
    “…The urine of DENV-, JEV-, and ZIKV-infected mice had 68, 64, and 47 different differential metabolites, respectively, compared with the urine of control mice. Among the metabolic pathways designed by these metabolites, ABC transporters, arginine and proline metabolism, and regulation of lipolysis play an important role. …”
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    Article
  10. 250

    Neuroprotection Caused by Hyperoxia Preconditioning in Animal Stroke Models by Mohammad Reza Bigdeli

    Published 2011-01-01
    “…The changes in the metabolic pathways are generally short lived and reversible, while the consequences of gene expression are a long-term process and may lead to the permanent alteration in the pattern of gene expression. …”
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  11. 251

    Extracellular vesicles—a new player in the development of urinary bladder cancer by Damian Kasiński, Kamil Szeliski, Tomasz Drewa, Marta Pokrywczyńska

    Published 2025-01-01
    “…EVs isolated from urinary bladder cancer cells affect other lower-grade cancer cells or normal cells by inducing different metabolic pathways (transforming growth factor β/Smads pathway; phosphoinositide 3-kinase/Akt pathway) that promote epithelial–mesenchymal transition. …”
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  12. 252

    Pantoprazole – safety in drug-drug interaction by E. V. Shikh, D. A. Sychev

    Published 2012-09-01
    “…To carry out comparative analysis of metabolic pathways of proton pump inhibitors (PPI), to determine the agent with lowest effect on activity of cytochrome CYP2C19 isoenzyme for improvement of safety of combined treatment by pharmaceuticals metabolized by this isoenzyme.Key points. …”
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  13. 253

    Role and Effective Therapeutic Target of Gut Microbiota in Heart Failure by Qiujin Jia, Hao Li, Huan Zhou, Xiaonan Zhang, Ao Zhang, Yingyu Xie, Yanyang Li, Shichao Lv, Junping Zhang

    Published 2019-01-01
    “…This paper introduced intestinal flora and its metabolites, summarized the changes of intestinal flora in patients with heart failure, clarified that intestinal barrier damage and bacterial translocation induced inflammation and immune response aggravated heart failure, and altered intestinal microflora affected various metabolic pathways including trimethylamine/TMAO, SCFA, and Bile acid pathway leads to heart failure. …”
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    Article
  14. 254

    Beyond the dichotomy: understanding the overlap between atopic dermatitis and psoriasis by Mengmeng Li, Jiangyi Wang, Qingfeng Liu, Youqing Liu, Wenyao Mi, Wei Li, Wei Li, Jingyi Li

    Published 2025-02-01
    “…We analyze the immunological networks, metabolic pathways, and microbial factors contributing to their development and progression. …”
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  15. 255

    Representative Metagenomes of Mesophilic Biogas Reactor Across South Korea by Darsha Prabhaharan, Young Wook Go, Hyunjin Kim, Seongcheol Kang, Byoung-In Sang

    Published 2025-02-01
    “…Over the past decade, this has driven global research on biogas-producing microbiomes, leading to significant advances in our understanding of microbial diversity and metabolic pathways within AD plants. However, substantial knowledge gaps persist, particularly in understanding the specific microbial communities involved in biogas production in countries such as South Korea. …”
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  16. 256

    Study on Effect of Producing Region on the Metabolome Composition of Rice by LIU Fu-ying, CHEN Xue-feng, WANG Xin, CHEN Guo-yan, GUO Ying, SUN Jing-han, YANG Shui-yan, NIE Xu-heng

    Published 2025-01-01
    “…By principal component analysis (PCA) and partial least square discriminant analysis (OPLS-DA), the results showed that the numbers of differential metabolites between the comparison groups (GJYH290 vs MLYH290, MZYH290 vs GJYH290, MZYH290 vs MLYH290) were 130, 180, and 192, respectively, only 6 different metabolites were common to all three comparison groups, with the main metabolic pathways involving amino acid metabolism and flavonoid metabolism. …”
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  17. 257

    Stevioside mitigates metabolic dysregulation in offspring induced by maternal high-fat diet: the role of gut microbiota-driven thermogenesis by Jin Ye, Renjie Shi, Xiaoning Wu, Hua Fan, Yapei Zhao, Xinyun Hu, Lulu Wang, Xiaowei Bo, Dongning Li, Yunshu Ge, Danna Wang, Bing Xia, Zhenting Zhao, Chunxia Xiao, Beita Zhao, Yutang Wang, Xuebo Liu

    Published 2025-12-01
    “…In summary, maternal STV supplementation could alleviate lipid metabolic disorders in offspring by enhancing L. apodemi levels and promoting thermogenic activity, potentially involving changes in bile acid metabolism pathways.…”
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  18. 258

    Peroxisome Proliferator-Activated Receptor γ and PGC-1α in Cancer: Dual Actions as Tumor Promoter and Suppressor by Seong-Hoon Yun, Sang-Heum Han, Joo-In Park

    Published 2018-01-01
    “…PPARγ coactivator-1α (PGC-1α), initially identified as a PPARγ-interacting protein, is an important regulator of diverse metabolic pathways, such as oxidative metabolism and energy homeostasis. …”
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  19. 259

    Multitargeted Effects of Vitexin and Isovitexin on Diabetes Mellitus and Its Complications by Ibrahim Luru Abdulai, Samuel Kojo Kwofie, Winfred Seth Gbewonyo, Daniel Boison, Joshua Buer Puplampu, Michael Buenor Adinortey

    Published 2021-01-01
    “…Data collected hint that vitexin and isovitexin work by targeting diverse pathophysiological and metabolic pathways and molecular drug points involved in the clinical manifestations of diabetes mellitus. …”
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    Article
  20. 260

    Transcriptome Analysis of Cryptolestes ferrugineus under Low-temperature Stress by WU Tian-yi, WU Yi, FANG Zhi-yi, ZHANG Xiao-pei, WANG Fu-ling, XUE Ding-rong

    Published 2025-01-01
    “…KEGG analysis revealed that differentially expressed genes were primarily enriched in metabolic pathways, fatty acid biosynthesis, and secondary metabolite biosynthesis. …”
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    Article