Dietary Chia (Salvia hispanica L.) seeds oil supplementation augments growth performance and gut microbial composition in Labeo rohita fingerlings by Sanjay Kumar Gupta, Akruti Gupta, Jaipal Singh Choudhary, Md Javed Foysal, Rajan Gupta, Biplab Sarkar, K. K. Krishnani

“…The predictions of metabolic pathways suggested the involvement of carbohydrate and amino acid metabolic pathways in the CSO (1) group, indicating improved nutrient transport and metabolism. …”
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Ningxiang pig-derived lactobacillus reuteri modulates host intramuscular fat deposition via branched-chain amino acid metabolism by Mei Yang, Qian Xie, Jing Wang, Andong Zha, Jiashun Chen, Qian Jiang, Meng Kang, Qiuchun Deng, Yulong Yin, Bie Tan

“…However, the specific microbes and metabolic pathways responsible for lipid deposition are still poorly understood. …”
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Transcriptomics Analysis of Maize (<i>Zea mays</i> L.) in Response to the Infection by <i>Setosphaeria turcica</i> by Hui Jia, Pan Li, Bu Tao, Yuwei Liu, Zhihang Liu, Mengfang Zhu, He Zhou, Maocun Wang, Jingao Dong, Shouqin Gu, Xiaodong Gong

“…Functional analysis revealed that these DEGs were enriched in multiple metabolic pathways. Notably, genes associated with “benzoxazinone biosynthesis”, “tetracyclic pyrrole biosynthesis”, and “photosynthesis” were all down-regulated. …”
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Correlation between follicle diameter and pre-ovulatory metabolic profile in Bos grunniens by Jiuru Yan, Jiuru Yan, Jiuru Yan, Yuxin Fu, Yuxin Fu, Yuxin Fu, Lan Lan, Huizhu Zhang, Huizhu Zhang, Huizhu Zhang, Ling Huang, Ling Huang, Yaying Wang, Yaying Wang, Xianrong Xiong, Xianrong Xiong, Xianrong Xiong, Shi Yin, Shi Yin, Shi Yin, Jian Li, Jian Li, Jian Li, Honghong He, Honghong He, Honghong He

“…Differential metabolites enriched KEGG pathways to screen the pathways that might be related to follicle development.ResultsWe found that most of the metabolites were mainly enriched in amino acid metabolism pathways, energy metabolism pathways and other pathways of cofactor synthesis, and that during the development of the small follicle to the large follicle, 2-Lysophosphatidylcholine, PC (17:0/0:0), PC (16:0/0:0), and LysoPC (18:0/0:0) were down-regulated; Dioctyl succinate, P-Coumaraldehyde, ISOPRENE, L-Isoleucine, Dioctyl succinate up-regulated.ConclusionThese results suggest that amino acid metabolism, the production of steroid hormones and their metabolites, and the metabolic activity of granulosa cells play important roles in follicle development. …”
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Exploring changes in metabolites and fecal microbiota of advanced gastric cancer based on plasma metabolomics and 16S rDNA sequencing by Xinyi Feng, Yu Zhang, Jun Feng, Zhongjun Li, Zhi Zhang, Lin Zhu, Ruoyu Zhou, Haibo Wang, Xiaojun Dai, Yanqing Liu

“…All metabolites were enriched into 42 differential metabolic pathways, of which 13 have P values less than 0.05. 16S rDNA sequencing showed significant differences in 4 microbial communities at the phylum level. …”
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Investigation of newborn blood metabolomics in varying intrauterine growth conditions by Shengwen Wang, Xiaofei Lin, Yu Zhou, Xin Yang, Mingming Ou, Linxin Zhang, Yumei Wang, Jing Gao

“…We aim to identify differential metabolites and metabolic pathways that may offer insights into clinical interventions. …”
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Gene Expression Pattern and Regulatory Network of α-Toxin Treatment in Bombyx mori by Tieshan Feng, Ping Lin, Jiao Gong, Dong Cheng, Xi Yang, Quan Zhang, Tingcai Cheng

“…The downregulated genes were mainly involved in the metabolic pathways of fundamental substances such as cellular protein metabolic process and nucleobase-containing compound metabolic process. …”
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FLAVONOID BIOSYNTHESIS GENES IN WHEAT by E. K. Khlestkina, O. Y. Shoeva, E. I. Gordeeva

“…The biosynthesis of flavonoid compounds is one of the best-studied metabolic pathways in plants. The researchers’ attention to the biochemical, physiological and genetic aspects of flavonoid biosynthesis is associated primarily with the wide range of their biological properties. …”
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Induction of phospholipase A2 group 4C by HCV infection regulates lipid droplet formation by Masahiko Ito, Jie Liu, Masayoshi Fukasawa, Koji Tsutsumi, Yumi Kanegae, Mitsutoshi Setou, Michinori Kohara, Tetsuro Suzuki

“…This study aimed to clarify the involvement of phospholipid metabolic pathways in the pathogenesis of HCV-induced steatosis. …”
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Detection of gene clusters for biodegradation of alkanes and aromatic compounds in the Rhodococcus qingshengii VKM Ac-2784D genome by Yu. A. Markova, I. S. Petrushin, L. A. Belovezhets

“…The R. qing­ shengii VKM Ac-2784D genome contains four out of eight known central metabolic pathways for the destruction of aromatic compounds. …”
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Integrated transcriptome and metabolome analysis of liver reveals unsynchronized growth mechanisms in blunt-snout bream (Megalobrama amblycephala) by Qi Liu, Xue Zou, Ming Zhao, Qianqian Guan, Zhaoyang Xuan, Lusha Liu, Zexia Gao

“…In addition, DEGs and DEMs in adenosine diphosphate (ATP) hydrolysis activity and associate with fatty acid metabolism, glucose metabolism, and amino acid metabolism pathways were both found in the transcriptomic and metabolomic integrated data. …”
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Genomic insights into the probiotic potential and genes linked to gallic acid metabolism in Pediococcus pentosaceus MBBL6 isolated from healthy cow milk. by Md Morshedur Rahman, Naim Siddique, Soharth Hasnat, Md Tanvir Rahman, Mustafizur Rahman, Munirul Alam, Ziban Chandra Das, Tofazzal Islam, M Nazmul Hoque

“…The genome also revealed primary metabolic pathways for arginine and gallic acid metabolism and secondary metabolite gene clusters, including T3PKS and RiPP-like regions. …”
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Effects of orally exposed SiO2 nanoparticles on lipid profiles in gut-liver axis of mice by Kuanhang Li, Zhengzheng Zhou, Yi Cao

“…Recently we proposed the possibility of orally exposed nanoparticles (NPs) to alter metabolite homeostasis by changing metabolism pathways, in addition to intestinal damages, but relatively few studies investigated the changes of metabolite profiles in multi-organs. …”
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The effects of Fraxini cortex and Andrographis herba on Escherichia coli-induced diarrhea in chicken by Yunying Wang, Zhenwei Sheng, Huicong Li, Xuewen Tan, Yingqiu Liu, Weimin Zhang, Wuren Ma, Lin Ma, Yunpeng Fan

“…This suggests that Fraxini cortex and Andrographis herba exerts an optimal effect on diarrhea by multi-target and multi-pathway regulation of metabolic pathways and gut microbiota.…”
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Metabolomics Unveiled the Accumulation Characteristics of Taste Compounds During the Development and Maturation of Litchi Fruit by Nonghui Jiang, Wei Liu, Zhidan Xiao, Xu Xiang, Yun Zhong

“…KEGG functional annotation and enrichment revealed that amino acid biosynthesis, D-amino acid metabolism, 2-oxocarboxylic acid metabolism, glyoxylate and dicarboxylate metabolism, the pentose phosphate pathway, the tricarboxylic acid cycle, and carbon metabolism were the most significantly enriched primary metabolic pathways. More differential metabolites and metabolic pathways indicated that the critical stage from the green fruit stage to the color transition stage laid a solid foundation for litchi flavor. …”
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Integrated metabolomics and proteomics revealed astragaloside IV inhibiting Pdxk-mediated vitamin B6 metabolism based on liquid chromatography-tandem mass spectrometry combined wit... by Shi Qiu, Sifan Guo, Zhibo Wang, Ying Cai, Dandan Xie, Wanying Sun, Aihua Zhang

“…Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite accumulation or deficiency which is well-recognized hallmarks of diseases. …”
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Estradiol metabolism by gut microbiota in women’s depression pathogenesis: inspiration from nature by Wei Zhang, Jinghan Jia, Yuhang Yang, Dawei Ye, Yan Li, Di Li, Jinxi Wang

“…Integrating existing studies on the regulation of estradiol metabolism by microorganisms in nature and the relevance of its degradation products to depression, recent scientific explorations have further elucidated the key mechanisms by which gut microbiota catabolize estradiol through specific metabolic pathways. These emerging scientific findings suggest that the unique metabolic effects of gut microbiota on estradiol may be one of the central drivers in the onset and course of depression in non-menopausal women.…”
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Transcriptomic Analysis of Pathogenicity Genes in Sclerotinia sclerotiorum Affecting Brassica napus by Hengameh Taheri, Mohamad Hamed Ghodoum Parizipour

“…These results demonstrated that S. sclerotiorum modulates some genes involved in disease induction (e.g., cell wall-degrading enzymes, biosynthesis of secondary metabolites & metabolic pathways) to infect its host plant.…”
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Trypanosoma cruzi Infection and Host Lipid Metabolism by Qianqian Miao, Momar Ndao

“…All of these factors are required to maintain host lipid homeostasis and are intricately connected via several metabolic pathways. We reviewed the interaction of T. cruzi with each of the relevant host components, in order to further understand the roles of host lipid metabolism in T. cruzi infection. …”
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The roles of KRAS in cancer metabolism, tumor microenvironment and clinical therapy by Qinglong Ma, Wenyang Zhang, Kongming Wu, Lei Shi

“…Abstract KRAS is one of the most mutated genes, driving alternations in metabolic pathways that include enhanced nutrient uptaking, increased glycolysis, elevated glutaminolysis, and heightened synthesis of fatty acids and nucleotides. …”
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