Comparative analysis of the intestinal flora of Siniperca chuatsi at different growth stages under three feeding practices by Yunyun Yan, Fubao Wang, Xiao Chen, Junjian Dong, Fengying Gao, Hetong Zhang, Xing Ye, Chengbin Wu, Chengfei Sun

“…Functional prediction revealed that the carbohydrate metabolism pathway was most enriched in the compound feed group, while the amino acid metabolism pathway was most enriched in the live bait group. …”
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Bioinformatics analysis of mitochondrial metabolism-related genes demonstrates their importance in renal cell carcinoma by Mohsen Ahmadi, Maryam Motallebinezhad, Pegah Mousavi, Amir Hossein Miladipour, Shamim Fooladgar, Soudeh Ghafouri-Fard, Seyed Amirhossein Fazeli

“…Conclusion The current study further proved the importance of mitochondrial metabolic pathways in the pathogenesis of ccRCC and provided a list of possible diagnostic markers and therapeutic targets from these pathways that can be used in ccRCC.…”
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Study on the Characteristics of Traditional Chinese Medicine Syndromes in Patients with Erosive Gastritis Based on Metabolomics by Zhang Shixiong, Liu Shaowei, Yang Zeqi, Xu Miaochan, Zhou Pingping, Bai Haiyan, Lv Jingjing, Wang Yangang

“…Similarly, in the LDQSS group, we identified 25 potential biomarkers and 18 metabolic pathways were enriched. The top five pathways were the TCA cycle, sphingolipid metabolism, fatty acid biosynthesis, pantothenate and CoA biosynthesis, and the pentose phosphate pathway. …”
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PbMYB5 transcription factor plays a role in regulating anthocyanin biosynthesis in pear (Pyrus bretschneideri Rehd) skin by Shangyun Li, Yutao Yang, Zhiwei Zhou, Xuan Zhou, Diya Lei, Ruiyuan He, Yunting Zhang, Jiliang Zhang, Yuanxiu Lin, Yan Wang, Mengyao Li, Wen He, Qing Chen, Ya Luo, Xiaorong Wang, Haoru Tang, Yong Zhang

“…Nevertheless, the precise regulatory functions of R2R3-MYB transcription factors in the metabolic pathways that regulate pear color changes remain unclear. …”
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Network Pharmacology Combined With Metabolomics Reveals the Mechanism of Yangxuerongjin Pill Against Type 2 Diabetic Peripheral Neuropathy in Rats by Jin R, Pei H, Yue F, Zhang X, Zhang Z, Xu Y, Li J

“…Metabolomics results showed that the potential metabolic pathways of YXRJP in the treatment of DPN mainly involved amino acid metabolism such as arginine, alanine, aspartic acid, lipid metabolism and nucleotide metabolism.Conclusion: YXRJP can effectively improve the symptoms of DPN rats and reduce nerve damage. …”
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Fermentation characteristics and probiotic activity of a purified fraction of polysaccharides from Fuzhuan brick tea by Guijie Chen, Ziqi Zeng, Minhao Xie, Yujia Peng, Wangting Zhou, Weiqi Xu, Yi Sun, Xiaoxiong Zeng, Zhonghua Liu

“…Furthermore, FBTPS-2-1 could regulate the biosynthesis and metabolism pathways of gut microbiota. Thus, the enrichment of food with FBTPS-2-1 is expected as a potential strategy for promoting human health due to modulation of gut microbiota.…”
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Hepatic transcript profiling in beef cattle: Effects of rumen-protected niacin supplementation. by Gastón F Alfaro, Valentino Palombo, Mariasilvia D'Andrea, Wenqi Cao, Yue Zhang, Jonathan Beever, Russell B Muntifering, Wilmer J Pacheco, Soren P Rodning, Xu Wang, Sonia J Moisá

“…Therefore, results from our study showed that the liver transcriptional machinery switched several metabolic pathways to a condition that could potentially benefit the health status of animals supplemented with rumen-protected niacin. …”
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Recent advances in nutritional metabolism studies on SARS-CoV-2 infection by Yufen Jiang, Linle Xu, Xuexing Zheng, Hongbo Shi

“…By monitoring metabolic changes, infection severity can be predicted early, and modulating these metabolic pathways may help reduce inflammatory responses, improve immune responses, and reduce the risk of thrombosis. …”
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Tartary buckwheat (Fagopyrum tataricum (L.) Gaertn) protein-derived antioxidant peptides: mechanisms of action and structure-activity relationship in Caco-2 cell models by Yiming Zhou, Xuanming She, Zhidong Chen, Yun Wei, Ying Xiao, Xiaoli Zhou

“…This indicated that CR-8 can improve the antioxidant capacity of damaged cells by intervening in multiple metabolic pathways. This also revealed the anti-oxidant mechanism of tartary buckwheat protein. …”
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Patient-derived cornea organoid model to study metabolomic characterization of rare disease: aniridia-associated keratopathy by Ali Can Koc, Vedat Sari, Gamze Kocak, Tuba Recber, Emirhan Nemutlu, Daniel Aberdam, Sinan Güven

“…Conclusions This study emphasizes the profound impact of AAK mutations on metabolism, particularly in amino acid biosynthesis and energy metabolism pathways.…”
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Identification of In Vivo Metabolites of Dictamnine in Mice Using HPLC-LTQ-Orbitrap Mass Spectrometry by Yudong Fu, Yujie Deng, Qing Yu, Xuxia Meng, Dabo Wang, Pei Wang, Ping Wang

“…To investigate the in vivo metabolic pathways of DIC, metabolism of DIC in mice was studied using a high-performance liquid chromatography coupled to electrospray ionization of hybrid linear trap quadrupole orbitrap (HPLC-LTQ-Orbitrap) mass spectrometer. …”
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The Opposite Effects of High-Sucrose and High-Fat Diet on Fatty Acid Oxidation and Very Low Density Lipoprotein Secretion in Rat Model of Metabolic Syndrome by Monika Cahova, Helena Dankova, Eliska Palenickova, Zuzana Papackova, Ludmila Kazdova

“…Diet type significantly affected partitioning of intracellular TAG-derived fatty acids among FFA-utilizing metabolic pathways as HS feeding accentuated VLDL secretion and downregulated FFA oxidation while the HF diet had an entirely opposite effect. …”
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Untangling the gut-brain axis: the relevance of gut microbiota in alcohol use disorder by Tommaso Dionisi, Valeria Maccauro, Giovanni Addolorato

“…Recent studies have shown that AUD has a significant impact on the Gut-Brain Axis (GBA), which involves a complex interplay of neuroimmunoendocrine and metabolic pathways.…”
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LC-MS/MS-based proteomics and metabolomics of HCT-116 colorectal cancer cells: A potential anticancer activity of atorvastatin by Refat M. Nimer, Hiba A. Nazazleh, Belal A. Al-Husein, Salah Abdelrazig, Lina Elsalem, Lina A. Dahabiyeh

“…These approaches were utilized to identify potential underlying metabolic pathways and proteins altered in atorvastatin (a statin)-treated HCT-116 cells. …”
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Deep-Sea-Derived Isobisvertinol Targets TLR4 to Exhibit Neuroprotective Activity via Anti-Inflammatory and Ferroptosis-Inhibitory Effects by Zi-Han Xu, Ming-Min Xie, Chun-Lan Xie, Xian-Wen Yang, Jun-Song Wang

“…Metabolomic analysis showed that <b>17</b> rescues alterations in multiple metabolic pathways induced by RSL3 and increases levels of antioxidant metabolites, including glutamine, glutamate, and glutathione. …”
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MCT1 lactate transporter blockade re-invigorates anti-tumor immunity through metabolic rewiring of dendritic cells in melanoma by Camille Niveau, Mélanie Cettour-Cave, Stéphane Mouret, Eleonora Sosa Cuevas, Mylene Pezet, Benoît Roubinet, Hugo Gil, Florence De Fraipont, Ludovic Landemarre, Julie Charles, Philippe Saas, Caroline Aspord

“…Our findings thus open the way for appropriate tuning of metabolic pathways to rescue DCs from tumor hijacking and restore potent antitumor responses.…”
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Metabolomics and transcriptomics analyses revealed overexpression of TaMGD enhances wheat plant heat stress resistance through multiple responses by Dongyun Ma, Haizhou Hu, Jianchao Feng, Beiming Xu, Chenyang Du, Yang Yang, Yingxin Xie, Chenyang Wang

“…Transcriptomic analysis suggests that overexpression of TaMGD influenced multiple metabolic pathways in response to high-temperature stress, including carbon metabolism, amino acid metabolism, photosynthesis, and lipid-related metabolism. …”
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Identification of serum biomarkers for cystic echinococcosis in sheep through untargeted metabolomic analysis using LC–MS/MS technology by Xiao-Xia Wu, Wan-Li Ban, Li-Jiang Wu, Wen-Jing Qi, Mehdi Borhani, Xiao-Ying He, Xiao-Lei Liu, Ming-Yuan Liu, Jing Ding

“…These differential metabolites are involved in various metabolic pathways, including amino acid metabolites (arginine, l-isoleucine, l-valine) and fatty acid metabolism (fenugreek, arachidonic acid, linolenic acid). …”
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Transcriptome analysis reveals the molecular mechanism of γ-linolenic acid eradicating the biofilm of vancomycin-resistant Enterococcus faecium by Ming Wei, Peng Wang, Tianmeng Li, Jun Liu, Yu Wang, Li Gu, Shuai Wang

“…In addition, KEGG analysis identified specific metabolic pathways that were significantly downregulated by GLA.ConclusionGLA effectively targets multiple aspects of biofilm formation in VRE-fm, including the downregulation of key biofilm-related genes, the inhibition of quorum sensing systems, and the modulation of metabolic pathways. …”
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A Narrative Review on Microbial Response to Antibiotic Stress: Mechanisms of Resistance and Adaptation by Nazia Khan

“…Additionally, the paper examines how microbial communities adapt to prolonged exposure through biofilm formation and altered metabolic pathways. Understanding these processes is crucial for developing strategies to combat antibiotic resistance and designing next-generation antimicrobial therapies.…”
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