Elevated mepolizumab levels in patients with severe asthma responsive to 1 year’s mepolizumab treatment by Takayasu Nishimaki, MD, Hitoshi Sasano, MD, PhD, Sonoko Harada, PhD, Tomohito Takeshige, MD, PhD, Yuuki Sandhu, MD, PhD, Yuki Tanabe, MD, Kei Matsuno, MD, PhD, Tetsutaro Nagaoka, MD, PhD, Jun Ito, MD, PhD, Ryo Atsuta, MD, PhD, Mayu Ohuchi, PhD, Shigehiro Yagishita, MD, PhD, Akinobu Hamada, PhD, Kazuhisa Takahashi, MD, PhD, Norihiro Harada, MD, PhD

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Updated insights into adverse events associated with mepolizumab: a disproportionality analysis from the FDA adverse event reporting system database by Shan Lin, Dachen Luo, Zonglian Gong, Qingyuan Zhan

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Study protocol for a randomized double-blinded placebo-controlled trial on mepolizumab for patients with chronic rhinosinusitis with nasal polyps, NSAID exacerbated respiratory dis... by Annina Lyly, Annina Lyly, Johanna Sahlman, Johanna Sahlman, Karoliina Pajala, Karoliina Pajala, Maija Salminen, Maija Salminen, Saara Sillanpää, Saara Sillanpää, Jura Numminen, Jura Numminen, Tanzeela Hanif, Tanzeela Hanif, Tanzeela Hanif, Anu Laulajainen-Hongisto, Mika Mäkelä, Paula Kauppi, Iiris Kangasniemi, Markus Lilja, Markus Lilja, Sari Hammaren-Malmi, Paula Virkkula, Sanna Toppila-Salmi, Sanna Toppila-Salmi, Sanna Toppila-Salmi

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Anti-IL5/IL-5 receptor therapies for eosinophilic granulomatosis with polyangiitis: an updated Systematic Review by Matteo Lazzeroni, Matteo Lazzeroni, Valeria Longoni, Paolo Schiavo, Emanuele Bizzi, Antonio Brucato, Giulia Gramellini, Marco Borin, Alberto Dragonetti, Michele Gaffuri, Mario Lentini, Antonino Maniaci, Angela Mauro, Antonio Gidaro, Jan Schroeder, Pasquale Capaccio, Pasquale Capaccio

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Economic evaluation and budgetary burden of mepolizumab in severe refractory eosinophilic asthma by Manuel David Gil-Sierra, Leticia García-Mochón, Emilio Jesús Alegre-del Rey, Catalina Alarcón de la Lastra-Romero, Marina Sánchez-Hidalgo

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Comparison of pharmacokinetic similarity, immunogenicity, and safety of mepolizumab and BAT2606 in healthy Chinese men in a double-blinded, randomized, single-dose, three-arm paral... by Cuiyun Li, Jixuan Sun, Jia Xu, Min Wu, Xiaojiao Li, Zhijie Liu, Qingfeng Dong, Yu Sun, Yanhua Ding

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Comparative Insights on IL-5 Targeting with Mepolizumab and Benralizumab: Enhancing EGPA Treatment Strategies by Mayu Shiomi, Ryu Watanabe, Ryuhei Ishihara, Sayaka Tanaka, Takashi Nakazawa, Motomu Hashimoto

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INTERLEUKIN-5 IS A NEW TARGET IN THE TREATMENT OF EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS by T. V. Beketova, E. V. Arseniev

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The outcomes of biologics in patients with CRSwNP among the Omani population by Sakina Al Lawati, Janan Al Abduwani, Iman Nasr, Latifa Alshekaili, Ruwaida Al Ismaili, Abdulaziz AL Azri, Zainab abdulhameed, Bushra Al Hinai, Salma Al Abri, Salma Al Habsi

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Steroid-sparing benefits of biologic use in hypereosinophilic syndrome and substantial disease burden across subtypes by Jeremiah Hwee, Lynn Huynh, Wilson da Costa, Marc E. Rothenberg, Mei Sheng Duh, Rafael Alfonso-Cristancho

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Early Intervention with Mepolizumab, Corticosteroids, and Intravenous Immunoglobulin for Dupilumab-Triggered Eosinophilic Granulomatosis with Polyangiitis: A Case Report by Kaburaki S, Tanaka T, Kamio K, Tanaka Y, Kasahara K, Seike M

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Utility of the Basophil Reactivity Test in the Clinical Management of People with Severe Uncontrolled Asthma by García Ródenas MDM, Hernández Blasco LM, Fernández Sánchez FJ, Marco de la Calle FM, Pascual-Lledó JF, Sánchez Barbie Á, Fernández Aracil C

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Monoclonal antibodies in severe asthma: outcomes from real-world data by Silvia del-Barrio-Buesa, Silvia del-Barrio-Buesa, Álvaro Narrillos-Moraza, Álvaro Narrillos-Moraza, Julia García-de-Pedro, Julia García-de-Pedro, Julia García-de-Pedro, Francisco Javier de-Castro-Martínez, Francisco Javier de-Castro-Martínez, María Esther Durán-García, María Esther Durán-García, Vicente Escudero-Vilaplana, Vicente Escudero-Vilaplana, Elena Lobato-Matilla, Elena Lobato-Matilla, Rosa Romero-Jimenez, Rosa Romero-Jimenez, Esther Chamorro-de-Vega, Esther Chamorro-de-Vega, Paula Ruiz-Briones, Paula Ruiz-Briones, Félix Jesús Garcia-Moreno, Félix Jesús Garcia-Moreno, María Martín-Bartolomé, María Martín-Bartolomé, Ana Herranz, Ana Herranz, María Sanjurjo, María Sanjurjo

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Pharmacoeconomic analysis of using biological agents for uncontrolled moderate-to-severe atopic asthma in the Russian Federation by S. K. Zyryanov, I. N. Diyakov, S. N. Avdeev

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Off-Label Use of Monoclonal Antibodies for Eosinophilic Esophagitis in Humans: A Scoping Review by Benyu Yang, Wenhan Li, Yiqiang Gao, Bo Zhang, Wei Zuo

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Efficacy of Mepolizumab in the Treatment of Severe Asthma with a Mixed Granulocytic Pattern of Airway Inflammation (Case Report) by A. M. Gubareva, S. V. Fedosenko, D. A. Vinokurova, S. V. Nesterovich, E. S. Kulikov, D. V. Polyakova, E. A. Starovoitova

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A Multicenter Retrospective Study Evaluating IL-5-Targeted Biologic Therapies for the Treatment of Asthma and Allergic Bronchopulmonary Aspergillosis in Adults With Cystic Fibrosis... by Sameer Desai, PhD, Sophia Shen, MD, Zosia Gryz, BSc, Elizabeth Tullis, MD, Anne L. Stephenson, MD, PhD, Bradley S. Quon, MD, MSc

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Two unique cases of eosinophilic granulomatosis with polyangiitis in childhood treated with anti-interleukin-5 therapy: infantile-onset and submandibular salivary gland involvement by Evangelia Constantine, Adam M. Bartholomeo, Inna Powers, Jerimiah L. Lysinger, Pia J. Hauk, Jordan Abbott, Heather H. de Keyser, Nicholas J. Gilman, Csaba Galambos, Angus Toland, Nicholas Willard, Jason Weinman, David Mong, Clara Lin, Jessica L. Bloom

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A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis by Sonia Iqbal, DO, Joseph A. Baxter, DO, Karla E. Adams, MD

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Prospective REALITI-A StudyTake-home Points by Cristiano Caruso, MD, PhD, G. Walter Canonica, MD, Manish Patel, MBChB, PhD, Andrew Smith, MBChB, PhD, Mark C. Liu, MD, Rafael Alfonso-Cristancho, MD, PhD, Robert G. Price, MSc, Rupert W. Jakes, PhD, Lydia Demetriou, MSc, Antonio Valero, MD, Thomas C. Köhler, MD, Charles Pilette, MD, PhD, Geoffrey Chupp, MD, Guy Brusselle, MD, Peter Howarth, DM

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