Gengnianchun Recipe Protects Ovarian Reserve of Rats Treated by 4-Vinylcyclohexene Diepoxide via the AKT Pathway by Fangui Zhao, Wenjun Wang

“…Gengnianchun recipe (GNC) is a traditional Chinese medicine formula originally applied to treat menopausal syndrome but is also found to be effective in treating clinical DOR patients. …”
Get full text

Comparison of Initial Clinical Presentations between Primary Hyperparathyroidism Patients from New Brunswick and Changsha by Lingqiong Meng, Shuying Liu, Aseel Al-Dayyeni, Zhifeng Sheng, Zhiguang Zhou, Xiangbing Wang

“…All these parameters were also compared according to gender and menopausal status. iPTH associations were also assessed along with several other parameters. …”
Get full text

Malignant phyllodes tumors with sarcomatous components: A histopathologic and molecular study by Ting Lei, Yunjie Song, Zhiyi Shen, Yongqiang Shi, Cunyan Xia, Xu Deng, Wenyue Da, Yan Peng, Qing Li

“…Results: Compared to MPT without sarcomatous components, no significant differences were found in age, tumor position, tumor size, menopausal status, or presence of fibroadenoma (p > 0.05). …”
Get full text

Influence of Cosmetic Skincare Products with pH < 5 on the Skin Microbiome: A Randomized Clinical Evaluation by Ciska Janssens-Böcker, Claudia Doberenz, Marta Monteiro, Marta de Oliveira Ferreira

“…Methods The clinical study focused on evaluating the skin microbiome diversity following the application for 28 days of four different low-pH cosmetic products (vitamin C, resveratrol, a collagen mask, and a native algae mask) on the forearms of post-menopausal women with skin pH > 5.5. Results The diversity of the natural skin microbiome increased consistently throughout the study, evident in both the untreated area and after the application of the Vitamin C Concentrate, Resveratrol Concentrate, Collagen Mask, and Native Algae Mask, as indicated by Shannon’s diversity index. …”
Get full text

Feasibility, safety and tolerability of estrogen and/or probiotics for improving vaginal health in Canadian African, Caribbean, and Black women: A pilot phase 1 clinical trial. by Biban Gill, Jocelyn M Wessels, Christina L Hayes, Jenna Ratcliffe, Junic Wokuri, Elizabeth Ball, Gregor Reid, Rupert Kaul, Jesleen Rana, Muna Alkhaifi, Wangari Tharao, Fiona Smaill, Charu Kaushic

“…<h4>Conclusion</h4>Overall, the administration of intravaginal estrogen and/or probiotics in pre-menopausal ACB women is feasible, safe, and well tolerated.…”
Get full text

Evaluation of Predictors of Response to Ovulation Induction Using Letrozole in Women with Polycystic Ovary Syndrome: A Prospective Cohort Study by Shanti Tholiya, Archana Kumari, Reeta Mahey, Mani Kalaivani, Hem Chandra Sati, Mona Sharma, Aarthi K. Jayraj, Neena Malhotra

“…OI was conducted using letrozole with or without human menopausal gonadotropin. Baseline endocrine and metabolic parameters, including serum AMH, FSH, LH, testosterone and FAI levels, were measured using ELISA or chemiluminescence methods on day 2 of the menstrual cycle. …”
Get full text

Predictors of plasma HDL-C concentrations in the Coronary Artery Risk Development in Young Adults (CARDIA) study by James M. Shikany, John R. Bassler, Jared P. Reis, Pamela J. Schreiner, David T. Redden, John T. Wilkins, Cora E. Lewis

“…Several factors were positively associated with HDL-C longitudinally in both women and men: age, self-identified Black race, alcohol intake, physical activity, and energy intake, along with sex-specific associations with current oral contraceptive use, current hormone therapy, and post-menopausal status (women only), and homeostasis model assessment-estimated insulin resistance (HOMA-IR) (men only). …”
Get full text

Clinicopathological and Prognostic Characteristics of Malaysian Triple Negative Breast Cancer Patients Undergoing TAC Chemotherapy Regimen by Ahmad Aizat Abdul Aziz, Md Salzihan Md Salleh, Ravindran Ankathil

“…Generally, clinicopathological features such as tumour size, patient’s age at diagnosis, tumour histology subtypes, grade and stage, involvement of lymph nodes, and menopausal status are commonly used for predicting disease progression, prospects of recurrence, and treatment response. …”
Get full text

Does the Temperature of the Distension Medium Affect Pain Perception in Patients undergoing Ambulatory Hysteroscopy? by Sai Kalmegh, Meenal Patvekar

“…Among the 60 patients, 40 (66.67%) were premenopausal, and 20 (33.33%) were menopausal. The most common indication was Abnormal Uterine Bleeding (AUB) in 17 (28.3%) patients. …”
Get full text

Computational studies and structural insights for discovery of potential natural aromatase modulators for hormone-dependent breast cancer by Snehal Aditya Arvindekar, Sanket Rathod, Prafulla Balkrishna Choudhari, Pradnya Kiran Mane, Aditya Umesh Arvindekar, Suraj Narayan Mali, Bapu Thorat

“…Generally 60%-75% of pre- and post-menopausal women suffer from estrogen-dependent breast cancer, and thus suppressing estrogen has been recognized to be a successful therapy. …”
Get full text

Factors Influencing the Pregnancy Outcome of Intrauterine Insemination and Follow-Up Treatment by Xuan Huang, Qin Sun, Xu Tang, Meiling Li, Cheng Zhou, Xi Cheng, Bing Yao, Li Chen

“…Further analysis showed that when patients with IUI had the following conditions: AMH &gt; 4.5 ng/ml, EMT between 8 and 12 mm and letrozole + human menopausal gonadotropin stimulation with higher clinical pregnancy. …”
Get full text

Urinary incontinence (UI) in older women in low- and middle-income countries: a rapid review and case study from Burkina Faso by Arthi Kozhumam, Mamadou Bountogo, Dina Goodman Palmer, Carolyn Grieg, Carolyn Grieg, Carolyn Grieg, Maxime Inghels, Maxime Inghels, Sandra Agyapong-Badu, Sandra Agyapong-Badu, Cristina Osborne, Guy Harling, Guy Harling, Guy Harling, Guy Harling, Till Bärnighausen, Till Bärnighausen, Till Bärnighausen, David Rapp, David Rapp, Molly Beestrum, Justine Davies, Justine Davies, Justine Davies, Lisa R. Hirschhorn

“…UI prevalence for LMIC women 40 or older varied greatly (6%–80%), with differences by socio-demographics, gynecological factors (menopausal status, birth outcomes), comorbidities (age, education, obesity, diabetes, hypertension, arthritis), behaviors (smoking status) and survey location. …”
Get full text

Clinical analysis of molecular typing of 146 cases of endometrial carcinoma by Bo Zhang, Bo Zhang, Dan Zhou, Shuo Zhang, Jinbowen Yan, Qingwei Meng, Qiubo Lv

“…Notably, significant associations were observed between menopausal status, the expression of ER, PR, and the four TCGA types. …”
Get full text

Evaluation of 902 Total Abdominal Hysterectomies Performed for Benign Reasons by Fazilet Kübra Boynukalın, Ömer Tolga Güler, Mehmet Coşkun, Özgür Özyüncü, Nasuh Utku Doğan

“…Among patients in whom bilateral salphingooophorectomy was performed, 569 (76.3%) were in pre-menopausal period. In 119 patients (13.2%) an additional surgical intervention was applied during operation. …”
Get full text

Breast cancer risk assessment based on a predictive model: evaluation of risk factors among Japanese women by Michiyo Yamada, Takashi Chishima, Takashi Ishikawa, Kazutaka Narui, Sadatoshi Sugae, Peter J. Tonellato, Itaru Endo

“…The logistic regression models included 18 variables from 6 risk factors based on menopausal status (PRE, premenopausal; PERI, perimenopausal; and POST, postmenopausal). …”
Get full text

Guidance for the gastrointestinal evaluation and management of iron deficiency in Sub-Saharan Africa by W M Simmonds, Y Awuku, C Barrett, M Brand, K Davidson, D Epstein, E Fredericks, S Gabriel, S Grobler, C Gounden, L Katsidzira, V J Louw, V Naidoo, C Noel, E Ogutu, N Ramonate, N Seabi, M Setshedi, J Van Zyl, G Watermeyer, C Kassianides

“…As iron deficiency (ID) anaemia in men and post-menopausal women is mostly caused by gastrointestinal blood loss or malabsorption, the initial evaluation of a patient with ID anaemia involves referral to a gastroenterologist. …”
Get full text

Association between long-term ambient air pollution exposure and the incidence of breast cancer: A meta-analysis based on updated evidence by Ruohan Wang, Peihan Wang, Yongkang Zhou, Yinan Wang, Chengdong Xu, Zhenbo Wang, Wei Wang

“…Subgroup analyses were performed based on menopausal status, hormone receptor subtype, and study region. …”
Get full text

Real-World Experience with CDK4/6 Inhibitors in the First-Line Palliative Setting for HR+/HER2− Advanced Breast Cancer by Ram Patel, John Mathews, Caroline Hamm, Swati Kulkarni, Rasna Gupta, Tarquin Opperman, John Dean Chiong, Abdullah Nasser

“…The Cox proportional hazards models adjusting for age and menopausal status found no significant differences between ribociclib and palbociclib for the PFS (HR = 0.92, <i>p</i> = 0.86) or OS (HR = 0.95, <i>p</i> = 0.92). …”
Get full text

Validation of biomarkers and clinical scores for the detection of uterine leiomyosarcoma: a case-control study with an update of pLMS by Marcus Vollmer, Günter Köhler, Julia Caroline Radosa, Marek Zygmunt, Julia Zimmermann, Martina Köller, Christine Seitz, Helena Bralo, Marc Philipp Radosa, Askin Cangül Kaya, Johann Krichbaum, Erich-Franz Solomayer, Lars Kaderali, Zaher Alwafai

“…LDH, NLR, and PLR achieved a diagnostic odds ratios of 18.03, 8.64 and 4.81, respectively. pLMS2 is based on subscores for menopausal status interacting with age, tumor diameter, intermenstrual bleeding, hypermenorrhea, dysmenorrhea, postmenstrual bleeding, rapid tumor growth, and suspicious sonography. …”
Get full text

Process Evaluations of Interventions for the Prevention of Type 2 Diabetes in Women With Gestational Diabetes Mellitus: Systematic Review by Iklil Iman Mohd Sa'id, Natasha Hotung, Madeleine Benton, Iliatha Papachristou Nadal, Anisah Baharom, Matthew Prina, Barakatun Nisak Mohd Yusof, Kimberley Goldsmith, Samantha Birts, Ching Siew Mooi, Angus Forbes, Khalida Ismail, Boon How Chew

“…Exclusion criteria were studies not published in English; studies where the target population was women who had a family history of T2D or women who were menopausal or postmenopausal; and gray literature, including abstracts in conference proceedings. …”
Get full text