Oncogenic Potential and Clinical Implications of Giant Endometrial Polyps: A Case Report and Literature Review by Brittany van Staalduinen, Andrew Stahler, Catherine Abied, Rita Shats, Nisha A. Lakhi

“…Risk factors of oncologic transformation include advanced age, menopausal status, obesity, diabetes, arterial hypertension, use of tamoxifen, and size greater than 1.0 centimeter. …”
Get full text

Successful Pregnancies after the Treatment of a Thymic Carcinoid by Wiebren A. A. Tjalma

“…In spite of her iatrogenic menopausal state she twice became pregnant and delivered two healthy babies but developed recurrences during both pregnancies. …”
Get full text

Takotsubo Cardiomyopathy as an Early Complication of Drug-Induced Suicide Attempt by Massimo Romanò, Federica Zorzoli, Roberta Bertona, Rosvaldo Villani

“…Takotsubo cardiomyopathy typically presents in menopausal women following episodes of intense physical or mental stress. …”
Get full text

Paraneoplastic anti-Yo antibody mediated subacute cerebellar degeneration. Case series and literature review by M. Vaišvilas, R. Mameniškienė, A. Barkauskienė

“…Paraneoplastic anti-Yo antibody mediated subacute cerebellar degeneration is characterised by an insidious onset, a characteristic neurologic syndrome of cerebellar dysfunction, normal or near/normal brain imaging on MRI, and gynaecologic malignancies identified by thorough investigation in middle aged post-menopausal women. Despite various aggressive treatments available, the prognosis is often considered poor. …”
Get full text

Estradiol metabolism by gut microbiota in women’s depression pathogenesis: inspiration from nature by Wei Zhang, Jinghan Jia, Yuhang Yang, Dawei Ye, Yan Li, Di Li, Jinxi Wang

“…These emerging scientific findings suggest that the unique metabolic effects of gut microbiota on estradiol may be one of the central drivers in the onset and course of depression in non-menopausal women.…”
Get full text

Hormonal-Receptors-Positive and HER2-Negative Patients with Metastatic Breast Cancer Treated with First-Line Palbociclib and Hormonal Therapy: Impact of First-Cycle Neutropenia and... by Khaled Abd Elaziz Ahmed Elnaghi, Hosam Ali Alghanmi, Shereef Ahmed Elsamany, Fathia Almarzoki, Mohamed Elsafty, Mohammad Jaffal

“…In addition, no difference was observed in PFS and OS according to ECOG PS (2 vs. 0-1) or menopausal status. Conclusion. No significant impact of the 1st cycle neutropenia, dose reduction, having ECOG PS2, menopausal status, or HER2 low status on survival outcome was observed. …”
Get full text

Primary Carcinoma in the Fallopian Tube: A Two Cases Report by Myriam García Tirada, Mario Joel Arroyo Díaz, Luis Enrique Pompa Montes de Oca, Ramón Portales Pérez, María Victoria López Soto

“…This carcinoma is most frequently presented in post menopausal women. Its clinical and histological behavior is often similar to that of an ovarian cancer. …”
Get full text

Impact of Obesity on Clinicopathologic Characteristics and Disease Prognosis in Pre- and Postmenopausal Breast Cancer Patients: A Retrospective Institutional Study by Nehad M. Ayoub, Rami J. Yaghan, Nour M. Abdo, Ismail I. Matalka, Laila M. Akhu-Zaheya, Alia H. Al-Mohtaseb

“…The analysis was stratified by menopausal status. Multivariate logistic stepwise regression analysis was conducted to identify predictors for breast cancer recurrence and death. …”
Get full text

Beneficial effects of the fructus Sophorae extract on experimentally induced osteoporosis in New Zealand white rabbits by CHAKULESKA LIDIJA, SHKONDROV ALEKSANDAR, POPOV GEORGI, ZLATEVA-PANAYOTOVA NADYA, PETROVA RENETA, ATANASOVA MARIYANA, KRASTEVA ILINA, DOYTCHINOVA IRINI, SIMEONOVA RUMYANA

“…Sophora japonica is a source of several flavonol, flavone and isoflavone glycosides that are reported to positively affect menopausal symptoms including osteoporotic complications. …”
Get full text

Liver Injury with Features Mimicking Autoimmune Hepatitis following the Use of Black Cohosh by Grace Guzman, Eric R. Kallwitz, Christina Wojewoda, Rohini Chennuri, Jamie Berkes, Thomas J. Layden, Scott J. Cotler

“…There are a growing number of cases detailing acute hepatic necrosis in patients taking black cohosh (Cimicifuga racemosa), an over-the-counter herbal supplement for management of menopausal symptoms. Our aim is to illustrate two cases of liver injury following the use of black cohosh characterized by histopathological features mimicking autoimmune hepatitis. …”
Get full text

The Significance of Soy Protein and Soy Bioactive Compounds in the Prophylaxis and Treatment of Osteoporosis by Sa'eed Bawa

“…Soy protein with naturally occurring phytoestrogens, mainly isoflavones protect against bone loss and synthetic soy ipriflavone in some studies has been shown to favorably affect, but a cause and effect relationship has not been established between the consumption of ipriflavone and maintenance of bone mineral density in post-menopausal women. Therefore it is too early to recommend it as a supplement for this group of women.…”
Get full text

Étude par absorptiométrie de la densité minérale osseuse dans une population médiévale (nécropole de Notre Dame du Bourg, Digne, Alpes de Haute-Provence France, XIe-XIIIe et XVIe-X... by Jean Fulpin, Bertrand Mafart, Pierre-Yves Chouc, Gabrielle Demians d'Archimbaud

“…The purpose of the study was to determine post-menopausal bone mineral content in women living in a semi-rural region at two different archaeological periods, i.e. …”
Get full text

Long-Term Followup of Adolescent and Young Adult Females with Hypergonadotropic Hypogonadism by Tsimaris Pantelis, Vrachnis Nikolaos, Iliodromiti Zoe, Deligeoroglou Efthymios

“…The condition characterized by elevated gonadotrophins (gonadotropins elevated into the menopausal range), low sex steroids, and menstrual disorders was previously termed Premature Ovarian Failure (POF). …”
Get full text

Paracrine activity of Smurf1-silenced mesenchymal stem cells enhances bone regeneration and reduces bone loss in postmenopausal osteoporosis by Alberto González-González, Itziar Álvarez-Iglesias, Daniel García-Sánchez, Monica Dotta, Ricardo Reyes, Ana Alfonso-Fernández, Alfonso Bolado-Carrancio, Patricia Díaz-Rodríguez, María Isabel Pérez-Núñez, José Carlos Rodríguez-Rey, Jesús Delgado-Calle, Flor M. Pérez-Campo

“…In vivo, studies were conducted using a rat ectopic bone formation model and a post-menopausal osteoporotic mouse model. Additionally, primary human osteoporotic MSCs were preconditioned with hCM-Smurf1, and their osteogenic capacity was compared to that induced by BMP2 treatment. …”
Get full text

Uterine Tumor Resembling Ovarian Sex-Cord Tumors Initially Diagnosed as a Prolapsed Fibroid by Fernando Augusto Rozário Garcia, Vanessa Pereira Gaigher, Rodrigo Neves Ferreira, Antônio Chambô Filho

“…First described in 1945 by Morehead and Bowman, uterine tumors resembling ovarian sex-cord tumors (UTROSCT) are rare tumors of the uterine body that tend to occur in menopausal women presenting with abnormal vaginal bleeding, abdominal pain, and increased uterine volume. …”
Get full text

Life stage impact on the human skin ecosystem: lipids and the microbial community by Martin P. Pagac, Bala Davient, Luca Antonio Plado, Hilbert Yuen In Lam, Shi Mun Lee, Aarthi Ravikrishnan, Wee Ling Esther Chua, Sneha Muralidharan, Aishwarya Sridharan, Antony S. Irudayaswamy, Ramasamy Srinivas, Stephen Wearne, Ahmad Nazri Mohamed Naim, Eliza Xin Pei Ho, H. Q. Amanda Ng, Junmei Samantha Kwah, Eileen Png, Anne K. Bendt, Markus R. Wenk, Federico Torta, Niranjan Nagarajan, John Common, Yap Seng Chong, Elizabeth Huiwen Tham, Lynette Pei-Chi Shek, Evelyn Xiu Ling Loo, John Chambers, Yik Weng Yew, Marie Loh, Thomas L. Dawson

“…This study investigated correlations between skin oxylipins and microbes on the superficial skin of pre-pubescent children (N = 36) and adults (N = 100), including pre- (N = 25) and post-menopausal females (N = 25). Lipidomics and metagenomics revealed that Malassezia restricta positively correlated with the oxylipin 9,10-DiHOME on adult skin and negatively correlated with its precursor, 9,10-EpOME, on pre-pubescent skin. …”
Get full text

Novel Action of FSH on Stem Cells in Adult Mammalian Ovary Induces Postnatal Oogenesis and Primordial Follicle Assembly by Deepa Bhartiya, Seema Parte, Hiren Patel, Kalpana Sriraman, Kusum Zaveri, Indira Hinduja

“…Stem cells are located in the ovary surface epithelium and exist in adult and menopausal ovary as well as in ovary with premature failure. …”
Get full text

The Unwritten Endings: A Deep Dive into the Story Completion Method in Management Research by Berivan Tatar

“…Our review of findings from seven studies shows that story completion-based research has focused on understanding the perception of menopausal women at work, teachers' teaching approach, and family life during the COVID-19 pandemic within the context of healthcare professionals, social workers, and teachers. …”
Get full text

Effectiveness of a Theory-Driven Nutritional Education Program in Improving Calcium Intake among Older Mauritian Adults by Trishnee Bhurosy, Rajesh Jeewon

“…Low calcium intake, a risk factor of osteoporosis and subsequent fractures, has been previously reported among post-menopausal women in Mauritius. Objective. To assess the effectiveness of a theory-based educational intervention in improving the calcium intake, self-efficacy, and knowledge of older Mauritians. …”
Get full text

Impact of Vitamin D on Skin Aging, and Age-Related Dermatological Conditions by Sankalya S. Ambagaspitiya, Gayan A. Appuhamillage, Sunil J. Wimalawansa

“…Intrinsic factors associated with advanced age gradually degrade the dermal collagen matrix, resulting in fine wrinkles and reduced elasticity; this is accelerated in post-menopausal women due to estrogen deficiency. In contrast, extrinsic factors associated with advanced age, primarily caused by exposure to ultraviolet (UV) radiation, lead to coarse wrinkles, solar elastosis, hyperkeratosis, irregular pigmentation, and skin cancers. …”
Get full text