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4521
Opinions on hypertension care and therapy adherence at the healthcare provider and healthcare system level: a qualitative study in the Hague, Netherlands
Published 2022-07-01“…Data were analysed using the theoretical domains framework (TDF) and the behaviour change wheel.Setting and participants Participants were from a highly urbanised city environment (the Hague, Netherlands), and included nine primary care physicians, six practice nurses and five secondary care physicians involved in hypertension care.Results Nine domains on the TDF were found to be relevant at the healthcare provider level (‘knowledge’, ‘physical, cognitive and interpersonal skills’, ‘memory, attention and decision processes’, ‘professional, social role and identity’, ‘optimism’, ‘beliefs about consequences’, ‘intention’, ‘emotion’ and ‘social influences’) and two domains (‘resources’ and ‘goals’) were found to be relevant at the system level. …”
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4522
Optimizing hypoglycaemia prediction in type 1 diabetes with Ensemble Machine Learning modeling
Published 2025-01-01“…., linear regression (LR), automatic relevance determination (ARD), support vector regression (SVR), Gaussian process regression (GPR), eXtreme gradient boosting (XGBoost), and long short-term memory (LSTM)), XGBoost and SVR showed a dominant performance in the hypoglycaemic region and were selected as the constituent basis models of the ensemble model. …”
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4523
Neurological function is restored post-ischemic stroke in zebrafish, with aging exerting a deleterious effect on its pathology
Published 2025-02-01“…Ischemic stroke (IS) is a pathological condition characterized by the cessation of blood flow due to factors such as thrombosis, inflicting severe damage to the cranial nervous system and resulting in numerous disabilities including memory impairments and hemiplegia. Despite the critical nature of this condition, therapeutic options remain limited, with a pressing challenge being the development of treatments aimed at restoring neurological function. …”
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4524
The Protective Effect of Mangiferin on Formaldehyde-Induced HT22 Cell Damage and Cognitive Impairment
Published 2023-05-01“…Further studies showed that the intragastric administration of 40 mg/kg/day MGF for 6 weeks significantly improved spatial learning ability and long-term memory in C57/BL6 mice with FA-induced cognitive impairment by reducing Tau hyperphosphorylation and the expression of GRP78, GSK-3β, and CaMKII in the brains. …”
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4525
HPLC-MS/MS-Mediated Analysis of the Pharmacokinetics, Bioavailability, and Tissue Distribution of Schisandrol B in Rats
Published 2021-01-01“…Schisandrol B, a lignan isolated from dried Schisandra chinensis fruits, has been shown to exhibit hepatoprotective, cardioprotective, renoprotective, and memory-enhancing properties. This study sought to design a sensitive and efficient HPLC-MS/MS approach to measuring Schisandrol B levels in rat plasma and tissues in order to assess the pharmacokinetics, oral bioavailability, and tissue distributions of this compound in vivo. …”
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4526
Different rs-fMRI Data Processing Methods in the Study of Vascular Cognitive Impairment
Published 2019-02-01“…About 40%of patients with cerebrovascular disease will have cognitive impairment, which can be expressed in different degrees of memory, language and visual space ability, and affect patients'daily activities, social interaction activities and work ability severely. …”
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4527
Acute beneficial effects of a functional energy shot on cognitive performance and mood states during cognitively demanding task performance: a randomized, double-blind, placebo-con...
Published 2025-01-01“…Additionally, the shot mitigated negative effects associated with extended cognitive tasks, reducing perceived mental fatigue and increasing perceived alertness and energy. Working memory tasks showed faster performance post-consumption, and mood assessments revealed positive effects on vigor, fatigue and overall mood disturbance.DiscussionThese results indicate wide cognitive and mood effects of this functional energy shot, potentially attributable to synergistic combination of active ingredients.Clinical trial registrationclinicaltrials.gov, identifier NCT06384586.…”
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4528
Adaptive Hosting Capacity Forecasting in Distribution Networks with Distributed Energy Resources
Published 2025-01-01“…This study introduces a Sensitivity-Enhanced Recurrent Neural Network (SERNN) model, featuring a sensitivity gate within the neural network’s memory cell architecture to enhance responsiveness to time-varying variables. …”
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4529
Regulatory T Cells Accumulate in the Lung Allergic Inflammation and Efficiently Suppress T-Cell Proliferation but Not Th2 Cytokine Production
Published 2012-01-01“…Lung regulatory T cells expressed an effector/memory phenotype (CCR4highCD62LlowCD44highCD54highCD69+) that distinguished them from naive regulatory T cells (CCR4intCD62LhighCD44intCD54intCD69−). …”
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4530
Justification of military neutrality of the Republic of Serbia at a time of erosion of neutrality in Europe
Published 2023-01-01“…Authors conclude that military neutrality represents a favorable strategic option for the Republic of Serbia, not just due to painful collective memory of Serbian citizens of the NATO aggression on Yugoslavia and the support of the Russian Federation to Serbia in regards to Kosovo and Metohija, but also due to the intrinsic values of neutrality which could become an identity attribute and a foundation of the renewal of solidarity in Serbian society.…”
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4531
Efficient Method for Robust Backdoor Detection and Removal in Feature Space Using Clean Data
Published 2025-01-01“…Secondly, it reduces the memory footprint and the computation time by at least an order of magnitude compared to other methods, which allows FEAT-IN to be used practically in real-world scenarios. …”
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4532
Digital screening tool for the assessment of cognitive impairment in unsupervised setting—digiDEM-SCREEN: study protocol for a validation study
Published 2025-01-01“…Recruitment will take place in specialised diagnostic facilities (memory outpatient clinics). 135 participants are aimed based on a power analysis. …”
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4533
NKG2C+CD57+ Natural Killer Cell Expansion Parallels Cytomegalovirus-Specific CD8+ T Cell Evolution towards Senescence
Published 2016-01-01“…Similar aspects of chronic HCMV infection may drive both NK and CD8+ T cell memory inflation.…”
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4534
Alloreactive-free CAR-VST therapy: a step forward in long-term tumor control in viral context
Published 2025-01-01“…In this review, we discuss the production methods of CAR-VSTs and explore optimization strategies to enhance their functionality, activation profiles, memory persistence, and exhaustion resistance. Emphasis is placed on their unique dual specificity for both antitumor and antiviral responses, along with an in-depth examination of preclinical and clinical outcomes. …”
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4535
Astaxanthin Protects Primary Hippocampal Neurons against Noxious Effects of Aβ-Oligomers
Published 2016-01-01“…We reported previously that amyloid-β peptide oligomers (AβOs) produce aberrant Ca2+ signals at sublethal concentrations and decrease the expression of type-2 ryanodine receptors (RyR2), which are crucial for hippocampal synaptic plasticity and memory. Here, we investigated whether the antioxidant agent astaxanthin (ATX) protects neurons from AβOs-induced excessive mitochondrial ROS generation, NFATc4 activation, and RyR2 mRNA downregulation. …”
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4536
Phytochemical screening and neuro-pharmacological activity of Mimosa pudica flowers: Integrating in vitro, in silico and in vivo approaches
Published 2025-02-01“…It also has effects on memory and learning, which could lead to significant gains in pharmaceutical development and medical progress.…”
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4537
Extracellular Vesicles Released from Neprilysin Gene-Modified Human Umbilical Cord-Derived Mesenchymal Stem Cell Enhance Therapeutic Effects in an Alzheimer’s Disease Animal Model...
Published 2021-01-01“…Both naïve and NEP-enhanced hUC-MSC groups showed significant improvements in memory compared to the Aβ1-42 injection group. There was no significant difference between naïve and NEP-enhanced hUC-MSC groups. …”
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4538
Detection of Alzheimer Disease in Neuroimages Using Vision Transformers: Systematic Review and Meta-Analysis
Published 2025-02-01“… BackgroundAlzheimer disease (AD) is a progressive condition characterized by cognitive decline and memory loss. Vision transformers (ViTs) are emerging as promising deep learning models in medical imaging, with potential applications in the detection and diagnosis of AD. …”
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4539
Design a Robust DDoS Attack Detection and Mitigation Scheme in SDN-Edge-IoT by Leveraging Machine Learning
Published 2025-01-01“…Consequently, XGBoost was deployed at the edge of the SDN-IoT for live traffic classification, showing improved performance by classifying live traffic within 3.946 ms and using only 8.80% of memory with a 0.5-second window size.…”
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4540
Exploring the Intersection of ADHD and Music: A Systematic Review
Published 2025-01-01“…Attention Deficit Hyperactivity Disorder (ADHD) is a highly prevalent neurodevelopmental disorder, affecting both children and adults, which often leads to significant difficulties with attention, impulsivity, and working memory. These challenges can impact various cognitive and perceptual domains, including music perception and performance. …”
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