Association of functional health literacy and cognitive ability with self-reported diabetes in the English Longitudinal Study of Ageing: a prospective cohort study by Ian J Deary, Chloe Fawns-Ritchie, Jackie Price

“…Objectives We investigated whether functional health literacy and cognitive ability were associated with self-reported diabetes.Design Prospective cohort study.Setting Data were from waves 2 (2004–2005) to 7 (2014–2015) of the English Longitudinal Study of Ageing (ELSA), a cohort study designed to be representative of adults aged 50 years and older living in England.Participants 8669 ELSA participants (mean age=66.7, SD=9.7) who completed a brief functional health literacy test assessing health-related reading comprehension, and 4 cognitive tests assessing declarative memory, processing speed and executive function at wave 2.Primary outcome measure Self-reported doctor diagnosis of diabetes.Results Logistic regression was used to examine cross-sectional (wave 2) associations of functional health literacy and cognitive ability with diabetes status. …”
Get full text

BDNF Levels and Cognitive Function in Patients with Type 2 Diabetes Treated with SGLT2 Inhibitors by Betül SÜMBÜL ŞEKERCİ, Şeymanur DEMİRHAN, Esra ÇALIŞICI, Abdüsselam ŞEKERCİ

“…Results: There were no significant differences between SGLT2 inhibitor users and metformin users in MoCA total scores, as well as in the Visuospatial/Executive, Naming, Attention, Language, Abstraction, Memory, and Orientation subdomains. Although BDNF levels were relatively higher in the SGLT2 inhibitor group, the difference was not statistically significant. …”
Get full text

Emergence of Exhausted B Cells in Asymptomatic HIV-1-Infected Patients Naïve for HAART is Related to Reduced Immune Surveillance by Manuela Fogli, Carlo Torti, Fabio Malacarne, Simona Fiorentini, Melania Albani, Ilaria Izzo, Cinzia Giagulli, Fabrizio Maggi, Giampiero Carosi, Arnaldo Caruso

“…A dramatic expansion of exhausted tissue-like memory B cells (CD10-CD21lowCD27-) was observed. B cells alteration was related to an increase in Torque teno virus (TTV) load, used as surrogate marker of immune function. …”
Get full text

Cerebral Responses to Acupuncture at GV24 and Bilateral GB13 in Rat Models of Alzheimer’s Disease by Shaoyang Cui, Mingzhu Xu, Jianting Huang, Qing Mei Wang, Xinsheng Lai, Binbin Nie, Baoci Shan, Xun Luo, John Wong, Chunzhi Tang

“…These results demonstrated that acupuncturing at GV24 and bilateral GB13 acupoints may improve the learning and memory abilities of the AD rats, probably via altering cerebral glucose metabolism (CGM) in the hypothalamus, thalamus, and brain stem. …”
Get full text

Recruitment Challenges and Strategies in a Technology-Based Intervention for Dementia Caregivers: Descriptive Study by Eunjung Ko, Ye Gao, Peng Wang, Lahiru Wijayasingha, Kathy D Wright, Kristina C Gordon, Hongning Wang, John A Stankovic, Karen M Rose

“…The recruitment involved two main methods: on-site engagement by a recruiter from a memory clinic and social media advertising. Caregivers were screened for eligibility by phone between January 2021 and September 2023. …”
Get full text

Forecasting Foreign Exchange Volatility Using Deep Learning Autoencoder-LSTM Techniques by Gunho Jung, Sun-Yong Choi

“…To this end, we propose a hybrid model that combines the long short-term memory (LSTM) and autoencoder models. These deep learning models are known to perform well in time-series prediction for forecasting FX volatility. …”
Get full text

Loss-of-function variant in MAGT1 leading to XMEN disease in a Colombian patient with a common variable immunodeficiency by Sebastián Gutiérrez-Hincapié, Julio César Orrego, José Luis Franco, Claudia M. Trujillo-Vargas

“…Common variable immunodeficiency is a diagnosis of exclusion in immunodeficient patients with increased susceptibility to infections, hypogammaglobulinemia, deficient response to vaccination, or low percentages of switched memory B cells. In low- and middle-income countries, the elucidation and study of molecular defects in these patients may take decades. …”
Get full text

Deteksi Dini Gangguan Jaringan Distributed Denial Of Service (DDOS) Menggunakan Metode Shannon Entropy Pada Software Defined Network (SDN) by Achmad Solichin, Ludi Nugroho

“…Tak hanya itu, serangan DDoS menyebabkan penurunan sumber daya jaringan seperti kapasitas memory dan CPU. Akibatnya kerusakan signifikan pada sistem yang menjadi korban serangan dapat mengalami kerugian, baik secara finansial, reputasi bahkan kehilangan pelanggan yang membutuhkan layanan tersebut. …”
Get full text

Efficient Encoding and Decoding of Voxelized Models for Machine Learning-Based Applications by Damjan Strnad, Stefan Kohek, Borut Zalik, Libor Vasa, Andrej Nerat

“…Storing, transmitting and consuming voxelized geometry, however, remains a challenging problem for machine learning pipelines running on devices with limited amount of on-chip memory with low access latency. A viable solution is to store the data in a compact encoded format, and perform on-the-fly decoding when it is needed for processing. …”
Get full text

Consumption of Nuts at Midlife and Healthy Aging in Women by Tania-Marisa Freitas-Simoes, Maude Wagner, Cecilia Samieri, Aleix Sala-Vila, Francine Grodstein

“…In 2012, those who survived beyond 65 years with no chronic diseases, no reported memory impairment, no physical disabilities, and intact mental health were considered “healthy agers.” …”
Get full text

Long-Term Environmental Enrichment Relieves Dysfunctional Cognition and Synaptic Protein Levels Induced by Prenatal Inflammation in Older CD-1 Mice by Zhe-Zhe Zhang, Li-Ping Zeng, Jing Chen, Yong-Fang Wu, Ya-Tao Wang, Lan Xia, Qi-Gang Yang, Fang Wang, Gui-Hai Chen

“…The Morris water maze (MWM) was used to assess the spatial learning and memory capacities of experimental mice, while western blotting and RNA-scope were used to determine the expression levels of Arc and Syt1 in the hippocampus at the protein and mRNA levels, respectively. …”
Get full text

Systematic review of innate immune responses against Mycobacterium tuberculosis complex infection in animal models by Luisa Maria Nieto Ramirez, Carolina Mehaffy, Karen Marie Dobos

“…Upon infection, Mtb induces various stages in the host, including early bacterial elimination, which may or may not involve memory responses. Deciphering the role of innate immune responses during MTBC infection is crucial for understanding disease progression or protection. …”
Get full text

Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder by Claudia Fuchs, Laura Gennaccaro, Stefania Trazzi, Stefano Bastianini, Simone Bettini, Viviana Lo Martire, Elisa Ren, Giorgio Medici, Giovanna Zoccoli, Roberto Rimondini, Elisabetta Ciani

“…We found that Cdkl5 +/− mice reliably recapitulate several aspects of CDKL5 disorder, including autistic-like behaviors, defects in motor coordination and memory performance, and breathing abnormalities. These defects are associated with neuroanatomical alterations, such as reduced dendritic arborization and spine density of hippocampal neurons. …”
Get full text

Metabolic reprogramming of naïve regulatory T cells by IL-7 and IL-15 promotes their persistence and performance upon adoptive transfer by Jessica Filoni, Arianna Ferrari, Tatiana Jofra, Anna Rita Putignano, Lorenzo Da Dalt, Susanna Cesarano, Carla Di Dedda, Fabrizia Bonacina, Federica Marchesi, Danilo Norata, Chiara Bonini, Lorenzo Piemonti, Paolo Monti

“…The final Treg product was enriched with cells displaying an immature CD45RA+CD62L+CD95+ phenotype, reminiscent of conventional memory stem T cells. The combination of IL-7 and IL-15 confers Tregs a glycolytic metabolism and improved metabolic fitness, characterized by an increased capacity to adapt metabolism according to glucose and oxygen availability. …”
Get full text

Deep Learning-Based Dynamic Stable Cluster Head Selection in VANET by Muhammad Asim Saleem, Zhou Shijie, Muhammad Umer Sarwar, Tanveer Ahmad, Amarah Maqbool, Casper Shikali Shivachi, Maham Tariq

“…A deep recurrent learning network, commonly known as long short-term memory (LSTM), is trained for the probability of detection with various signals and noise conditions. …”
Get full text

Evaluating empirical and machine learning approaches for reference evapotranspiration estimation using limited climatic variables in Nepal by Erica Shrestha, Suyog Poudyal, Anup Ghimire, Shrena Maharjan, Manoj Lamichhane, Sushant Mehan

“…We assessed the performance of six widely used empirical models (Hargreaves Samani, modified Hargreaves Samani, Romanenko, Schendel, Priestley-Taylor, and Makkink) and four ML models (random forest, extreme gradient boosting, deep neural network, and long short-term memory) to estimate ET0 with limited climatic variables in Nepal. …”
Get full text

Modeling of wave-induced drift based on stepwise parameter calibration by Kui Zhu, Xueyao Chen, Lin Mu, Lin Mu, Lin Mu, Dingfeng Yu, Dingfeng Yu, Runze Yu, Zhaolong Sun, Tong Zhou, Tong Zhou

“…A force analysis method and three ML methods, long short-term memory (LSTM), back-propagation (BP) neural network, and random forest (RF), were used to fit the wave-induced drift velocity by combining eight different parameter schemes. …”
Get full text

Clinical and radiological characteristics and 1-year self-reported outcomes from patients with encephalitis and coronavirus disease 2019 by Nathane Braga da Silva Rezende, Fernanda Gomes de Queiroz Barros-Aragão, Talita Pinto, Viviane Tavares Carvalho Crelier, Marcos Ravi Figueiredo, Carlos Otávio Brandão, Andrea Silveira de Souza, Fernanda Tovar-Moll, Gabriel R. de Freitas

“…In the outcome analysis, most patients (77%) reported gait difficulties and 66% reported memory and concentration problems. Conclusion Encephalitis associated with severe acute respiratory syndrome coronavirus 2 infection is rare but responsible for chronic sequelae in cognitive and motor aspects. …”
Get full text

Cultural validation of the Addenbrooke’s Cognitive Examination Version III Urdu for the British Urdu-speaking population: a qualitative assessment using cognitive interviewing by Nadine Mirza, Maria Panagioti, Waquas Waheed

“…Across 19 ACE-III Urdu items, 7 required changes based on participant feedback: item 5a: fluency; items 6, 18 and 19: memory; items 12 and 13: language; and item 17: visuospatial abilities.The need for some of these changes was realised after 21 participants, due to persistently reoccurring issues, and these were applied before the last four participants. …”
Get full text

A narrative review about cognitive impairment in Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD): Another matter to face through a holistic approach by Marica Meroni, Miriam Longo, Erika Paolini, Paola Dongiovanni

“…Indeed, cognitive decline in MASLD translates in low concentration and processing speed, reduced memory, sleepiness but also anxiety and depression. …”
Get full text