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161
Genetic and epigenetic alterations in night shift nurses with breast cancer: a narrative review
Published 2025-01-01“…This review hypothesizes that disruptions in the sleep-wake cycle, such as changes in melatonin production and telomere length, could contribute to breast cancer susceptibility. …”
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162
Systematic study of drug distribution profiles of different nanocarriers in the skin layers: a more accurate and targeted delivery
Published 2024-12-01“… The aim of this work was to evaluate the skin distributions of two drugs with different logarithm of the distribution coefficient (Log D) values. Melatonin (MEL; Log D 1.74) and benzophenone-3 (BZA-3; Log D 3.88) lipid core nanocapsules (LNCs) were prepared with poly(e-caprolactone) (PCL) of different molar weights (14,000 g mol-1 and 80,000 g mol-1), capric/caprylic triglyceride, sorbitan monostearate and polysorbate 80, and nanoemulsions (NE) were similarly prepared without polymer. …”
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163
Agomelatine Efficacy in the Night Eating Syndrome
Published 2013-01-01“…This paper describes a case report of an NES patient treated with agomelatine, an antidepressant analogue of melatonin, which acts by improving not only the mood but also by regulating sleep cycles and appetite. …”
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164
Suvorexant, a Novel Dual Orexin Receptor Antagonist, for the Management of Insomnia
Published 2023-01-01“…While there are many existing treatments such as benzodiazepines, melatonin agonists, TCAs, and atypical antipsychotics used to target various receptors involved in normal induction and maintenance of sleep, Suvorexant is an antagonist that specifically targets orexin receptors. …”
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165
Nocturnal Light Pollution Synergistically Impairs Glucose Metabolism With Age and Weight in Monkeys
Published 2024-01-01“…The results show that nocturnal light (1) caused premature deaths in individuals with preexisting diabetes; (2) intensity-dependently induced diabetes and IGT in previous healthy monkeys; (3) intensity-dependently reduced melatonin secretion; (4) had a synergistic impairing effect on glucose metabolism with aging and weight; and (5) although monkeys would eventually adapt to the environment, the disrupted glucose metabolism would not fully recover in most individuals. …”
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166
Evaluating the Impact of Oil Refinery on Landscape Values Perception and Mental Health: A Case Study of Tehran
Published 2025-01-01“…It can be reduced through exercise, which lowers stress hormones, and exposure to daylight, which regulates hormones such as cortisol and melatonin. Furthermore, the design and perception of the environment can indicate danger or safety, influencing stress levels and mental health. …”
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167
Insomnia: definition, pathophysiological models, diagnosis, and treatment
Published 2018-09-01“…Antihistaminics and antipsychotics are not recommended for insomnia treatment because of insufficient evidence. Melatonin is not recommended for the treatment of insomnia because of low efficacy. …”
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168
高浓度褪黑素对麝鼠香腺中<italic>FGF20</italic>基因表达的影响
Published 2024-05-01“…麝鼠(<italic>Ondatra zibethicus</italic>)是一种具有较高经济价值的香料动物和毛皮动物。在一些毛皮动物生产中常使用褪黑素(melatonin,MT)来获得更高的效益,但MT对麝鼠香腺发育的作用尚不清楚,为了探究高浓度MT对麝鼠香腺中<italic>FGF20</italic>基因表达的影响,通过RT-qPCR技术检测高浓度MT处理组与对照组麝鼠香腺中<italic>FGF20</italic>基因的转录水平。…”
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169
Microbiota for production of wine with enhanced functional components
Published 2023-09-01“…Microorganisms not only drive alcohol fermentation, flavor and aroma, but also enhance wine functional components such as extraction of polyphenols from the berries, production of γ-aminobutyric acid, hydroxytyrosol and melatonin. Polyphenols such as resveratrol, catechin and quercetin determine the functional quality of the wine. …”
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170
Fatigue in Medical Residents Leads to Reactivation of Herpes Virus Latency
Published 2011-01-01“…DNA of human herpes viruses HSV-1, VZV, EBV, as well as cortisol and melatonin concentrations, were measured in saliva. …”
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171
Protective Action of Antioxidants on Hepatic Damage Induced by Griseofulvin
Published 2014-01-01“…The aim was to evaluate the possible protective effect of different antioxidant compounds: trolox (Tx), ascorbic acid (Asc), the combination Tx and Asc, melatonin (Mel), and the polyphenols: ellagic acid, quercetin, chlorogenic acid, caffeic acid, gallic acid, and ferulic acid on liver damage and oxidative stress markers in a mouse model of EPP. …”
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172
Evaluation of the effects of a team‐based systematic prevention and management program for postoperative orthopedic older patients: A retrospective cohort study
Published 2024-12-01“…Results After the DELTA program's implementation, a significant decrease in benzodiazepine receptor agonist prescriptions (odds ratio [OR], 0.39; 95% confidence interval [CI], 0.29–0.53) and an increase in prescriptions of either melatonin receptor agonists or dual orexin receptor antagonists (OR, 3.83; 95% CI, 2.49–5.88) were observed. …”
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173
Feasibility and acceptability for LION, a fully remote, randomized clinical trial within the VA for light therapy to improve sleep in Veterans with and without TBI: An MTBI2 sponso...
Published 2025-01-01“…Secondary/exploratory outcomes included cognition, mood, quality of life, circadian rhythm via dim light melatonin onset, and biofluid-based biomarkers. Participant drop out occurred in <10% of those enrolled, incomplete/missing data was present in <15% of key outcome variables, and overall fidelity adherence to the intervention was >85%, collectively establishing feasibility and acceptability for MBLT in Veterans with mTBI.…”
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174
Research Progress on Sugar Signaling during Fruit Development and Ripening
Published 2024-10-01“…Among them, phytohormones that regulate sugar metabolism during fruit development and ripening mainly include abscisic acid (ABA), auxin, ethylene (ETH), gibberellins (GA), brassinosteroids (BR), salicylic acid (SA), jasmonic acid (JA) and melatonin (MT), etc. In addition, fruit color is one of the key characteristics of fruit quality, which is crucial to the nutritional and commercial value of fruits, and is mainly affected by anthocyanin and carotenoid accumulation or chlorophyll degradation. …”
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175
Association between sleep deprivation and fertility - a literature review
Published 2025-02-01“…Temporarily the impact of sleep depravation is being inconsistent about estradiol, prolactin and melatonin. This article presents a meticulously collected date which shows the connection between sleep and punctuate need for further research. …”
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176
Clinical and genetic aspects of albinism
Published 2021-09-01“… Zinchenko</b> </p> <p> <b>Research Center for Medical Genetics, Moscow, Russian Federation</b> </p> <p> <i>Albinism is a clinically and genetically heterogeneous group of hereditary diseases whose pathogenesis is mediated by impaired synthesis of melanin which results in its partial or total loss. Reduced melatonin level clinically manifests as skin, hair, and ocular hypopigmentation. …”
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177
Sleep Disorders and Reproductive Health: Mechanisms, Consequences, and Potential Interventions
Published 2025-02-01“…Recent findings emphasize that mindfulness techniques, cognitive-behavioral therapy, improved sleep hygiene, and even melatonin supplementation may contribute to the success of infertility treatments, including assisted reproductive techniques. …”
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178
Unveiling the molecular and cellular links between obstructive sleep apnea-hypopnea syndrome and vascular aging
Published 2025-01-01“…This review examines the molecular and cellular features common to both OSAHS and VA, highlighting decreased melatonin secretion, impaired autophagy, increased apoptosis, increased inflammation and pyroptosis, increased oxidative stress, accelerated telomere shortening, accelerated stem cell depletion, metabolic disorders, imbalanced protein homeostasis, epigenetic alterations, and dysregulated neurohormonal signaling. …”
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179
Seasonal Changes in Sleep Duration in African American and African College Students Living In Washington, D.C.
Published 2007-01-01“…Duration of nocturnal melatonin secretion, a marker of “biological night” that relates to sleep duration, is longer in winter than in summer in patients with seasonal affective disorder (SAD), but not in healthy controls. …”
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180
Taxifolin increased semen quality of Duroc boars by improving gut microbes and blood metabolites
Published 2022-10-01“…TAX increased the blood concentration of testosterone derivatives, antioxidants such as melatonin and betaine, unsaturated fatty acids such as DHA, and beneficial amino acids such as proline. …”
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