Carbohydrate ligand engagement with CD11b enhances differentiation of tumor-associated myeloid cells for immunotherapy of solid cancers by Mei Zhang, Veronique Roche, Victor Sandoval, Claire Wolford, Zachary Senders, Julian Anthony Kim, Susan Pereira Ribeiro, Alex Yicheng Huang, Rafick-Pierre Sekaly, Joshua Lyons

“…This engagement significantly impacts the biological function of tumor-associated inflammatory monocytes (TAIMs) in osteosarcoma, advanced melanoma, and PDAC backgrounds. Importantly, we observed that the BG34-200-CD11b engagement triggered endocytosis of the binding complexes in TAIMs, which induced intracellular F-actin cytoskeletal rearrangement, effective phagocytosis, and intrinsic ICAM-1 (intercellular adhesion molecule I) clustering. …”
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Reconstrucción de defectos totales del ala nasal utilizando el colgajo frontal by Lenia Sánchez Wals, Dayne García García

“…La creciente incidencia del cáncer de piel, no melanoma, ha motivado la consulta frecuente de pacientes portadores de carcinomas en localizaciones fotoexpuestas, como el ala nasal. …”
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Leptin Promotes Glioblastoma by Johnathan E. Lawrence, Nicholas J. Cook, Richard A. Rovin, Robert J. Winn

“…In animal models of colon cancer and melanoma, a decline in the expression and secretion of leptin resulted in a reduction of tumor growth. …”
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Anticytotoxic T-Lymphocyte Antigen-4 Induced Autoimmune Hypophysitis: A Case Report and Literature Review by Deborah Majchel, Mary T. Korytkowski

“…Autoimmune hypophysitis, a previously described rare disorder, is being recognized more frequently as a side effect of novel immunomodulatory agents used in the treatment of malignancies such as melanoma. CTLA-4 agents are associated with immune-related adverse effects (irAE) which occur as a result of activation (or lack of inactivation) of the immune response. …”
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Verification and Optimal Control of Context-Sensitive Probabilistic Boolean Networks Using Model Checking and Polynomial Optimization by Koichi Kobayashi, Kunihiko Hiraishi

“…Finally, a numerical example on the WNT5A network, which is related to melanoma, is presented. The proposed methods provide us useful tools in control theory of GRNs.…”
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Multiple Pigmented Bowen’s Disease: A Diagnostic and Therapeutic Dilemma by Pratik Gahalaut, Madhur Kant Rastogi, Nitin Mishra, Sandhya Chauhan

“…Here we present an otherwise healthy Indian male having multiple pigmented lesions of BD on sun-protected sites of the body mimicking malignant melanoma. These lesions were refractory to treatment with different modalities. …”
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Usability and Usefulness of a Symptom Management Coaching System for Patients With Cancer Treated With Immune Checkpoint Inhibitors: Comparative Mixed Methods Study by Savannah Lucia Caterina Glaser, Itske Fraterman, Noah van Brummelen, Valentina Tibollo, Laura Maria Del Campo, Henk Mallo, Sofie Wilgenhof, Szymon Wilk, Vitali Gisko, Vadzim Khadakou, Ronald Cornet, Manuel Ottaviano, Stephanie Medlock

“…A prototype of the eHealth tool Cancer Patients Better Life Experience (CAPABLE) was developed to facilitate symptom management, aimed at patients with melanoma and renal cell carcinoma treated with immunotherapy. …”
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Case report: A severe myositis mimicking bulbar palsy after administration of immune checkpoint inhibitors by Philippe Rochigneux, Philippe Rochigneux, Alexandre Bertucci, Elika Loir, Alexia Mattei, Danielle Robert, Michael Dassa, Brice Chanez, Mikael Ebbo, Lea Gaigne, Anne Sophie Chretien, Giovanni Corazza, Giovanni Corazza, Nicolas Schleinitz

“…After 4 years of follow-up, and only one infusion of Ipi/Nivo, the melanoma is still in complete response.ConclusionWe report an ICI-induced severe myositis mimicking bulbar palsy after the administration of Ipi/Nivo. …”
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Radiotherapy for Metastatic Merkel Cell Carcinoma: A Review of the Literature by Luluel Khan, Elizabeth A. Barnes

“…Merkel cell carcinoma is a rare form of non-melanoma skin cancer of neuroendocrine origin. Optimal management of patients is controversial and the role of radiotherapy is unclear. …”
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Adjuvants for peptide-based cancer vaccines by Willem W Overwijk, Hiep Khong

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Recent Progress of Genome Study for Anaplastic Thyroid Cancer by Jieun Lee, Jung-Ah Hwang, Eun Kyung Lee

“…Although targeted treatment of genetic alterations has emerged as an extremely promising approach to human cancers, such as BRAF in metastatic melanoma, it remains unclear that how commonly genomic alterations are influenced in ATC tumorigenesis. …”
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Retinal Toxicity after Initial Administration of Nivolumab and Ipilimumab by Adnan Kilani, Efstathios Vounotrypidis, Susanna F. König, Armin Wolf

“…A 52-year-old female with metastatic malignant cutaneous melanoma experiencing bilateral progressive visual acuity reduction, after treatment initiation with 1 mg/kg nivolumab and 3 mg/kg ipilimumab two weeks prior symptom onset. …”
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Advances in nucleic acid-based cancer vaccines by Hung-Chun Liao, Shih-Jen Liu

“…In oncology, the combination of mRNA vaccine encoding neoantigens and immune checkpoint inhibitors (ICIs) has shown remarkable efficacy in eliciting protective responses against diseases like melanoma and pancreatic cancer. Although the use of a COVID-19 DNA vaccine has been limited to India, the inherent stability at room temperature and cost-effectiveness of DNA vaccines present a viable option that could benefit developing countries. …”
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Aging impairs CD8 T cell responses in adoptive T-cell therapy against solid tumors by Gulfiya Kadyrzhanova, Miho Tamai, Shukla Sarkar, Rajkumar Singh Kalra, Hiroki Ishikawa

“…Here, using a mouse model of melanoma, we demonstrate that aging diminishes anti-tumor activity of engineered CD8 T cells expressing a tumor-specific T cell receptor (CD8 TCR-T cells) in ACT for solid tumors. …”
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Recurrence of Dysplastic Nevi Is Strongly Associated with Extension of the Lesions to the Lateral Margins and into the Deep Margins through the Hair Follicles in the Original Shave... by Amin Maghari

“…Melanocytic nevi, including dysplastic or atypical nevi (DN), can recur or persist following shave removal procedures, and recurrence may resemble melanoma, both clinically and histologically (pseudomelanoma). …”
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Reconstrucción mayor de un nevo congénito gigante en la región facial: técnica quirúrgica by David R. De Rungs-Brown, Manuel González-Guevara, Ruben Kershenovich-Tavel, Armando Mansilla-Alba

“…El nevo congénito gigante puede presentar como complicación mayor la aparición de un melanoma que resulte fatal para el pronóstico del paciente. …”
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Monte carlo simulation of heterotypic cell aggregation in nonlinear shear flow by Jiakou Wang, Margaret J. Slattery, Meghan Henty Hoskins, Shile Liang, Cheng Dong, Qiang Du

“…In particular,we focus on leukocyte (PMN)-melanoma cell emboli formation and subsequenttethering to the vascular endothelium (EC) as a result of cell-cell aggregation.The simulation results are compared with the results of experimental measurement.Discussions are made on how we could further improve the accuracy ofthe population balance type modelling.…”
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Giant Conjunctival Nevus in a 12-Year-Old Child by Edit Tóth-Molnár, Eszter Vizvári, Ákos Skribek, András Vörös

“…Although giant conjunctival nevus is a rare entity, precise diagnosis and adequate management are very important as it can be confused with malignant melanoma.…”
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A Review on the Antimutagenic and Anticancer Effects of Cysteamine by Chun-Man Lee

“…The efficacy of cysteamine has been shown in vitro and in vivo for the treatment of different types of cancer, such as gastrointestinal cancer, pancreatic cancer, sarcomas, hepatocellular carcinoma, and melanoma, leading to the significant reduction of lesions and/or the increase of survival time. …”
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Prothrombin Complex Concentrate for Rapid Reversal of Warfarin Anticoagulation to Allow Neuraxial Blockade by Conor Skerritt, Stephen Mannion

“…The patient then underwent excision of melanoma deposits from her leg and groin dissection. …”
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