Photochemical Treatment of Drosophila APCs Can Eliminate Associated Viruses and Maintain the APC Function for Generating Antigen-Specific CTLs Ex Vivo by Jun Ye, Chunxia Yang, Zeling Cai, Weixing Shi, Hong Yu

“…Using Drosophila APCs, CTLs specific for melanoma antigens have been generated in vitro and adoptively transferred to melanoma patients. …”
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Expression and Significance of AQP3 in Cutaneous Lesions by Dongfeng Niu, Yanhua Bai, Qian Yao, Wei Hou, Lixin Zhou, Xiaozheng Huang, Chen Zhao

“…Only focal AQP3 staining was seen in nevocellular nevus and no AQP3 staining in melanoma. Our findings indicate the function of AQP3 maintained in most skin tumors. …”
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Kinetics of Mushroom Tyrosinase and Melanogenesis Inhibition by N-Acetyl-pentapeptides by Ching-Yi Lien, Ching-Yu Chen, Shih-Ting Lai, Chin-Feng Chan

“…The melanogenesis inhibition of Ac-P4 was dose-dependent and did not induce any cytotoxicity on B16F10 melanoma cells.…”
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Tectonic Keratoplasty to Restore the Bulbar Wall after Block Excision of Benign and Malignant Intraocular Tumors by Emilio Balestrazzi, Luigi Mosca, Maria Antonietta Blasi, Maria Ilaria Giannico, Angelo Balestrazzi

“…Two patients were affected by anterior uveal malignant melanoma, and 2 patients were referred to us for large epithelial iris cysts with anterior chamber angle involvement and partial corneal failure. …”
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A Case of Nivolumab-Induced Severe Mononeuropathy Multiplex and Rhabdomyolysis by Katsuya Sakai, Hitoshi Mochizuki, Kosuke Mochida, Kazutaka Shiomi, Masahiro Amano, Masamitsu Nakazato

“…We report an 81-year-old man with multiple liver metastases after tumorectomy for primary mediastinal malignant melanoma, who experienced limb weakness and sensory disturbance after nivolumab monotherapy. …”
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Transposon mediated functional genomic screening for BRAF inhibitor resistance reveals convergent Hippo and MAPK pathway activation events by Li Chen, Iulian Pruteanu-Malinici, Anahita Dastur, Xunqin Yin, Dennie Frederick, Ruslan I. Sadreyev, Cyril H. Benes

“…Abstract Genotype-informed anticancer therapies such as BRAF inhibitors can show remarkable clinical efficacy in BRAF-mutant melanoma; however, drug resistance poses a major hurdle to successful cancer treatment. …”
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Correction: The landscape of BRAF transcript and protein variants in human cancer by Andrea Marranci, Zhijie Jiang, Marianna Vitiello, Elena Guzzolino, Laura Comelli, Samanta Sarti, Simone Lubrano, Cinzia Franchin, Ileabett Echevarría-Vargas, Andrea Tuccoli, Alberto Mercatanti, Monica Evangelista, Paolo Sportoletti, Giorgio Cozza, Ettore Luzi, Enrico Capobianco, Jessie Villanueva, Giorgio Arrigoni, Giovanni Signore, Silvia Rocchiccioli, Letizia Pitto, Nicholas Tsinoremas, Laura Poliseno

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A novel approach to earlobe reconstruction using the V to Y advancement flap by Laura Allen, Kelti Munroe, S. Mark Taylor

“…All patients had a non-melanoma skin cancer involving the earlobe. All surgeries were performed under local anesthetic at a tertiary care centre in Halifax, Canada. …”
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Selective expression and significance of ACKR2 in lung aerocytes by Alberto Mantovani, Gianluigi Condorelli, Raffaella Bonecchi, Massimo Locati, Marina Sironi, Roberta Carriero, Francesca Albano, Valeria Mollica Poeta, Lucia Zotti, Alessandra Castagna, Arianna Felicetta, Alessandro Mesaglio, Elisa Zaghen, Arianna Capucetti, Rachele Di Donato, Mattia Laffranchi, Matteo Massara, Silvano Sozzani

“…In vivo models of lung metastasis and inflammation were performed in wild-type (WT) and conditional KO mice by intravenous injection of melanoma and colon cancer cell lines; the induction of acute lung injury model was done by intranasal injection of lipopolysaccharide (LPS). …”
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Trojan-horse silk fibroin nanocarriers loaded with a re-call antigen to redirect immunity against cancer by Luca Mastracci, Patrizio Castagnola, Elia Bari, Francesca Ferrera, Tiziana Altosole, Sara Perteghella, Pierluigi Mauri, Rossana Rossi, Giulia Passignani, Martina Galati, Giuseppina Iliana Astone, Maddalena Mastrogiacomo, Daniela Fenoglio, Dario Di Silvestre, Maria Luisa Torre, Gilberto Filaci

“…Proof-of-concept of in vivo efficacy was achieved in an OVA-hyperimmune B16/F10 murine melanoma model: SFNs-OVA or SFNs-CpG were injected, separately or in association, into the subcutaneous peritumoral area. …”
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Studi Retrospektif Kanker Kulit di Poliklinik Ilmu Kesehatan Kulit dan Kelamin RS Dr. M. Djamil Padang Periode Tahun 2015-2017 by Silvia Wilvestra, Sri Lestari, Ennesta Asri

“…Kesimpulan: Karsinoma non-melanoma merupakan kanker kulit yang paling banyak ditemukan di dunia. …”
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Revealing Genomic Profile That Underlies Tropism of Myeloma Cells Using Whole Exome Sequencing by Youngil Koh, Daeyoon Kim, Woo-June Jung, Kwang-Sung Ahn, Sung-Soo Yoon

“…Genetic signature of cutaneous plasmacytoma shares that of melanoma implying common mechanism for skin tropism. …”
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Immunotherapy-associated autoimmune hemolytic anemia by Uqba Khan, Tarik Hadid, Farman Ali, Muhammad Siddique Khurram, Awais Zaka

“…The following case represents an unusual adverse effect of combined treatment with ipilimumab and nivolumab used for treatment of metastatic melanoma.Case presentation A 43-year-old woman with metastatic melanoma presented with severe generalized weakness and fatigue. …”
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Functional-proteomics-based investigation of the cellular response to farnesyltransferase inhibition in lung cancer by Yanbo Pan, Olena Berkovska, Soumitra Marathe, Georgios Mermelekas, Greta Gudoityte, Amare D. Wolide, Taner Arslan, Brinton Seashore-Ludlow, Janne Lehtiö, Lukas M. Orre

“…Key findings include the potential therapeutic value of FTIs for NRAS-mutated melanoma and GNAQ/GNA11-mutated uveal melanoma by inhibiting INPP5A farnesylation. …”
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A Severe Case of Ipilimumab-Induced Ileocolitis Refractory to Glucocorticosteroids and Infliximab by Behdod Poushanchi, Hiren Vallabh, Gorman Joel Reynolds

“…Ipilimumab is a monoclonal antibody that works as an immunotherapeutic agent through selective targeting of T cells to strengthen the response to metastatic melanoma. It is well known that this pharmaceutical agent can cause the adverse effect of colitis. …”
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CASE PRESENTATION by Goga Iolanda, Cioc Enache, Boghici Elena-Monica, Moraru Mihaela, Nichita Monica-Adriana, Dumitrescu Elena, Pirlea Andrei-Daniel, Zob Daniela-Luminiţa

“…Diffuse large B-cell lymphoma and metachronous metastatic renal cancer – a case report Malignant melanoma of the leg – challenges. A case report Clinical and therapeutic particularities in dermatofibrosarcoma protuberans – a case report Multiple myeloma presenting as sellar plasmacytoma and focal and segmental glomerulosclerosis – case report…”
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Enhancing magnetic hyperthermia: Investigating iron oxide nanoparticle coating and stability by Joana Santos, Jorge Carvalho Silva, Manuel A. Valente, Tânia Vieira, Paula I.P. Soares

“…Interaction studies with three cell lines (fibroblasts, melanoma, and macrophages) revealed enhanced internalization of APTES-coated SPIONs. …”
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Analysis of the Stockholm Public Health Cohort: Exploring How Ultraviolet Radiation and Other Factors Associate with Skin Cancer by Lina U. Ivert, Henrik Dal, Ylva Rodvall, Bernt Lindelöf

“…A 5% level of significance was applied. Melanoma in situ and SCC in situ were excluded. Results. …”
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Resetting the Hsc70-mediated lysosomal degradation of PD-L1 via a supramolecular meso peptide for the restoration of acquired anti-tumor T cell immunity by Yujia Zhao, Dan Liu, Wenguang Yang, Wangxiao He, Jin Yan, Leiqing Yao

“…As expected, CTAC-PDL1 effectively reactivated Hsc70-mediated lysosomal degradation of PD-L1 and consequently restored anti-tumor T cell immunity in a B16F10-derived mouse model of malignant melanoma while maintaining a favorable safety profile. …”
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Newer Clinical Strategies for Combining Interferon and Cytotoxic Agents Against Solid Tumours and Hematological Malignancies by Scott Wadler

“…Clinical benefits have been observed for combinations of interferons and alkylating agents against low grade lymphomas, interferons and dacarbazine against malignant melanoma, and interferons and 5-fluorouracil against gastrointestinal and genitourinary malignancies. …”
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