Synthesis and Anti-Inflammatory Activity of a Novel Series of Diphenyl-1,2,4-triazoles and Related Derivatives by Swapna Cherala, Harikiran Lingabathula, Rama Ganta, Srinivas Ampati, Sarangapani Manda

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Third Derivative Spectrophotometric Method for Simultaneous Determination of Copper and Nickel Using 6-(2-Naphthyl)-2, 3-dihydro-1,2,4- triazine-3-thione by Maliheh Barazandeh Tehrani, Effat Souri

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COVID19: The biggest barrier against Oral oncology therapy? by Kannan RR. Rengasamy

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Evaluation of the rainfed and irrigated conditions on biomass and essential oil yield of German chamomile (Matricaria chamomilla) in response to melatonin foliar application by Hossein Gorgini Shabankareh, Mohammad Reza Asgharipour, Ali Salehi Sardoei, Ahmad Reza Kamaliun, Hamid Mohammadi, Mansour Ghorbanpour

“…Abstract German chamomile (Matricaria chamomilla L.) is a valuable medicinal plant known for its rich content of bioactive compounds, including chamazulene, α-bisabolol, and α-bisabololoxide A. …”
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Management of chimeric antigen receptor T-cell-related toxicity of a patient affected by cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome, follo... by G. Menardi, A. Castellino, C. Castellino, M. E. Bersia, E. Grande, G. Fraternali, M. Massaia, C. Fruttero

“…Brexucabtagene autoleucel, a US Food and Drug and European Medicines Agency-approved anti-CD19 chimeric antigen receptor T-cell therapy, marks a significant breakthrough offering hope in this challenging scenario. …”
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Mechanism of Action of <i>Fusarium oxysporum</i> CCS043 Utilizing Allelochemicals for Rhizosphere Colonization and Enhanced Infection Activity in <i>Rehmannia glutinosa</i> by Feiyue Yuan, Fuxiang Qiu, Jiawei Xie, Yongxi Fan, Bao Zhang, Tingting Zhang, Zhongyi Zhang, Li Gu, Mingjie Li

“…<i>Rehmannia glutinosa</i> is an important medicinal herb; but its long-term cultivation often leads to continuous cropping problems. …”
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Using the WHO building blocks to examine cross-border public health surveillance in MENA by Laura Buback, Shayanne Martin, Esbeydy Pardo, Farah Massoud, Jesus Formigo, Atousa Bonyani, Noha H. Farag, Zayid K. Almayahi, Kenta Ishii, Susie Welty, Dana Schneider

“…Recommendations emphasize strengthened governance and leadership to facilitate regional cooperation and information sharing, sustainable financing for implementing a One Health approach, utilizing innovative information systems, workforce development to enhance data collection and analysis, and secure supply chains for medicines and vaccines and equitable service delivery for all mobile populations. …”
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The effect of a barley-based food product in alleviating knee osteoarthritis discomfort symptoms in Egyptian female patients by Suzanne Fouad, Rasha Monir, Fatma A. Ibrahim, Ahmed M.S. Hussein, Heba F. Shafei, Aliaa El Gendy

“…There are numerous conventional treatments available, including nonsteroidal anti-inflammatory medicines and pharmaceuticals containing glucosamine; however, taking them can result in serious side effects. …”
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Development of Coconut Milk-Based Spicy Ice Cream as a Nondairy Alternative with Desired Physicochemical and Sensory Attributes by K. D. S. S. Perera, O. D. A. N. Perera

“…Spices are identified as one of the most distinctive ingredients for their indigenous flavor, aroma, and medicinal properties. In this study, coconut milk-based spicy ice cream was developed in compliance with the Sri Lankan standards to introduce a new perception of flavor using spices to the ice cream industry. …”
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Nivolumab plasma concentration and clearance associated with overall survival in patients with renal cell carcinoma by Aurélien Marabelle, Laurence Albiges, Angelo Paci, Cécile Dalban, David Combarel, Sophie Broutin, Christophe Maritaz, Louis Blondel

“…Applying the model to a patient population with renal cell carcinoma identified nivolumab clearance and plasma concentration as predictors of overall survival (OS).Methods A custom liquid chromatography with tandem mass spectrometry method for quantifying nivolumab plasma concentration was developed and validated following the European Medicines Agency guidelines for bioanalytical method validation. …”
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Suberosin attenuates rheumatoid arthritis by repolarizing macrophages and inhibiting synovitis via the JAK/STAT signaling pathway by Huan Liu, Qianwei Li, Yuehong Chen, Min Dong, Hongjiang Liu, Jiaqian Zhang, Leiyi Yang, Geng Yin, Qibing Xie

“…Suberosin (SBR), isolated from Plumbago zeylanica—a medicinal plant traditionally used to treat RA in Asia—possesses notable biological activities. …”
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Association of Breastfeeding with Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis in mothers: A cross sectional survey by Muhammad Zafar Majeed Babar, Ghulam Mustafa, Manzur Ahmad Manzur, Hafiz Haseeb Ahsan

“…Subject having history of alcohol consumption or used medicines like glucocorticoids, amiodarone, tamoxifen, and methotrexate were excluded from the study. …”
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Predicting the Most Deleterious Missense Nonsynonymous Single-Nucleotide Polymorphisms of Hennekam Syndrome-Causing CCBE1 Gene, In Silico Analysis by Khyber Shinwari, Liu Guojun, Svetlana S. Deryabina, Mikhail A. Bolkov, Irina A. Tuzankina, Valery A. Chereshnev

“…These highly deleterious nsSNPs can be used as marker pathogenic variants in the mutational diagnosis of the HS syndrome, and this research also offers potential insights that will aid in the development of precision medicines. CCBE1 proteins from Hennekam syndrome patients should be tested in animal models for this purpose.…”
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Ameliorative effect of curcuminoids in liver fibrosis rat model via regulating GIPC1 gene and modulating MMP-8/TIMP-3 balance mediated by miR-483-5p by Rana Mostafa Adel, Sara Mostafa Kamal, Eman Adel Sherif, Sara Hatem El-shafiey

“…Curcuminoids, especially curcumin (CURC), are medicinal extracts that proved their antioxidative, anti-inflammatory, antifibrotic actions, and showed wide epigenetic regulatory effects. …”
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Complete chloroplast genome of eight Phaius (Orchidaceae) species from China: comparative analysis and phylogenetic relationship by Kaifeng Tao, Lu Tang, Yan Luo, Lu Li

“…(Collabieae, Orchidaceae) is a small genus consisting of about 45 species, with highly ornamental and medicinal values. However, the phylogenetic relationship of Phaius among Calanthe s. l. has been highly debated based on morphological and molecular data. …”
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Primary dysmenorrhea: pathophysiology, improvement of diagnostic and treatment possibilities by T.V. Fartushok, N.V. Fartushok

“…Primary dysmenorrhea is one of the types of gynecological pathology, the frequency of which is 45-53% in girls and young women aged 13 to 45 years, which is not given enough attention in diagnosis and treatment.The pathogenesis takes into account the increased secretion of prostaglandins F2α and E2 in the period from the beginning of pregnancy to birth, which cause pelvic pain.The diagnosis is based on the patient's history, symptoms, examination, the treatment is aimed at improving the quality of life by prescribing nonsteroidal anti-inflammatory drugs, hormonal contraceptives and the use of non-medicinal means. Purpose: to specify some links in the pathogenesis of primary dysmenorrhea and, taking into account its multicomponent nature, to evaluate the effectiveness of the proposed treatment. …”
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Therapeutic potential of Curcuma longa against monkeypox: antioxidant, anti-inflammatory, and computational insights by Farouk Boudou, Amal Belakredar, Ahcen Keziz, Linda Aissani, Huda Alsaeedi, David Cronu, Mikhael Bechelany, Mikhael Bechelany, Ahmed Barhoum

“…Curcuma longa (turmeric) is a widely used medicinal plant known for its antioxidant and anti-inflammatory properties, primarily attributed to its bioactive curcuminoids.AimThis study aimed to evaluate the therapeutic potential of C. longa aqueous extract (CAE) against monkeypox through phytochemical characterization, biological assays, and computational analyses.MethodologyPhytochemical analysis, including HPLC, identified key Curcumin, Bisdemethoxycurcumin, Demethoxycurcumin, Tetrahydrocurcumin, Curcuminol, and Ar-curcumene. …”
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Evaluation of the diagnostic accuracy of two point-of-care tests for COVID-19 when used in symptomatic patients in community settings in the UK primary care COVID diagnostic accura... by Brian D Nicholson, Philip J Turner, Thomas R Fanshawe, Alice J Williams, Gayatri Amirthalingam, Sharon Tonner, Maria Zambon, Richard Body, Kerrie Davies, Rafael Perera, Simon de Lusignan, Gail N Hayward, F D Richard Hobbs, RAPTOR-C19 Study Group and the CONDOR Steering Committee

“…<h4>Conclusions</h4>Both POCTs assessed exceed the Medicines and Healthcare products Regulatory Agency target product profile's minimum acceptable specificity of 95%. …”
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Exploration of Degradation Mechanism of Chlorogenic Acids in Stevia Based on UPLC-QTOF MS/MS by Juan-juan WU, Zi-xuan WANG, Yun-he LIAN, Li-juan HOU, Zhi-ping NIU, Wen-chang WANG, Di WU

“…Chlorogenic acids (caffeoylquinic acids, CQAs), as key bioactive components in numerous traditional herbal medicines, are highly acclaimed for their various biological activities and therapeutic benefits. …”
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Ethnobotanical Study on Wild Edible Plants in Metema District, Amhara Regional State, Ethiopia by Getinet Masresha, Yirgalem Melkamu, Getnet Chekole Walle

“…Most of the species (33, 75%) were used as animal fodder followed with traditional medicines (25, 56.82%) and firewood (20, 45.45%). Tamarindus indica, Moringa stenopetala, Balanites aegyptiaca, Grewia ferruginea, Corchorus olitorius, and Cordia africana had nutraceutical values. …”
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