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  9. 56309

    A multi-country cohort database study to assess pregnancy and infant outcomes after potential maternal or paternal exposure to cladribine tablets in the treatment of multiple scler... by Kerstin Hellwig, Melinda Magyari, Thomas M. MacDonald, Carolyn E. Cesta, Stig Wergeland, Maarit K. Leinonen, Asher Ornoy, Sandra Vukusic, Alexandra Lauer, Xiaolei Zhou, Alison Kawai, Rachel Weinrib, Alejandro Arana, Tahani Boumenna

    Published 2025-01-01
    “…Conclusion: The CLEAR study, using a staggered methodological approach, aims to provide further insight into the safety outcome data for cladribine tablets in pregnant women, as a regulatory commitment with the European Medicines Agency. Trial registration: EU PAS Register number, EUPAS25027.…”
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  10. 56310

    (<i>aS</i>)-Glucosciadopitysin, a New Biflavonoid Glycoside from the Leaves of <i>Ginkgo biloba</i> and Osteogenic Activity of Bioflavonoids by Se Yun Jeong, Kwang Ho Lee, Seon Hee Kim, Min Hye Yang, Gakyung Lee, Ki Hyun Kim

    Published 2025-01-01
    “…The leaves of <i>Ginkgo biloba</i> have been used in treating freckles and effectively reducing cough and sputum in folk medicines. Recently, investigations into the correlation between ginkgo leaves and the proliferative activity of osteogenic differentiation have been conducted. …”
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  11. 56311

    Xi Lei San Attenuates Dextran Sulfate Sodium-Induced Colitis in Rats and TNF-α-Stimulated Colitis in CACO2 Cells: Involvement of the NLRP3 Inflammasome and Autophagy by Zhang Tao, Xiaoqing Zhou, Yan Zhang, Wenfeng Pu, Yi Yang, Fuxia Wei, Qian Zhou, Lin Zhang, Zhonghan Du, Ji Wu

    Published 2021-01-01
    “…The active ingredients of traditional Chinese medicines (TCMs) exert anti-inflammatory, antitumor, and immunomodulatory effects, and their multitarget characteristics provide them with a unique advantage for treating IBD. …”
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  12. 56312

    Eye reactions under the influence of drugs of abuse as measured by smartphones: a controlled clinical study in healthy volunteers by Kiki W. K. Kuijpers, Karl Andersson, Karl Andersson, Maria Winkvist, Marieke Niesters, Monique van Velzen, Fred Nyberg, Albert Dahan, Markku D. Hämäläinen

    Published 2025-01-01
    “…Still, comprehensive quantitative evaluations under known ambient light conditions are lacking, when smartphones are used for monitoring.MethodsIn this clinical study (NCT05731999), four medicinal products with addiction risks were administered to 48 subjects (18–70 years old, all with informed consent, 12 subjects per drug). …”
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  13. 56313

    The impact of prolonged blockade of the releasing hormone on alterations in cardiac macrophage polarisation subsequent to quercetin administration in rats by T.A. Voroshylova, V.I. Shepitko, Ye.V. Stetsuk, N.V. Boruta, O.V. Vilkhova, M.V. Rud, G.S. Puzyryov, O.V. Sych, А.A. Miahkokhlib

    Published 2024-12-01
    “…Quercetin is an organic substance belonging to the flavonoid family with a wide range of medicinal properties. The purpose of our study was to ascertain the impact of testosterone suppression on immunocompetent heart cells in male rats. …”
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  14. 56314

    Effects of Prosopis farcta Root Extract in the Vascular Reactivity of Isolated Goat Coronary Artery by Rezhna Adil Rasheed, Ismail Salih Ibrahim Kakey

    Published 2019-08-01
    “…Prosopis species is a medicinal plant, well-known for its beneficial effects in treating various smooth muscles disorders, and its phytochemical analysis revealed the presence of different bioactive compounds in different parts of the plant, most of which show a great role in reducing cardiovascular risks. …”
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  15. 56315

    An Overview on The Pandemic Coronavirus Disease 2019 (COVID-19) Outbreak by Mariwan Abdulla Hama Salih

    Published 2020-05-01
    “…At the moment nothing can stop the virus from spreading, neither vaccine nor medicines were found to stop the virus and secure life of people of the planet.  …”
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  16. 56316

    Effect of the Hydroethanolic Extract of Bixa orellana Linn (Bixaceae) Leaves on Castor Oil-Induced Diarrhea in Swiss Albino Mice by Michel Archange Fokam Tagne, Hypolyte Akaou, Paul Aimé Noubissi, Angèle Foyet Fondjo, Yaouke Rékabi, Henri Wambe, René Kamgang, Jean-Louis Essame Oyono

    Published 2019-01-01
    “…The treatment of diarrheal diseases is a serious problem in developing countries, where population generally uses medicinal plants. The leaves of Bixa orellana have been reported to be traditionally used in the treatment of diarrhea by local people in the district of Khulna in Bangladesh. …”
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  17. 56317

    Integrated Transcriptomic and Targeted Metabolomic Analysis Reveals the Key Genes Involved in Triterpenoid Biosynthesis of <i>Ganoderma lucidum</i> by Xiaolan Xu, Chunxia Li, Fangjing Wu, Shuangshuang Zhao, Tiqiang Chen, Haihong You, Yijie Lin, Xiaoxing Zou

    Published 2025-01-01
    “…<i>Ganoderma lucidum</i> is a traditional Chinese medicinal fungus, and ganoderma triterpenoids (GTs) are one of the main bioactive compounds. …”
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  18. 56318

    Preliminary Exploration of Natural Polyphenols and/or Herbal Mix Replacing Sodium Nitrate to Improve the Storage Quality of Pork Sausage by Angeliki-Niki Kaloudi, Agori Karageorgou, Michael Goliomytis, Panagiotis Simitzis

    Published 2025-01-01
    “…As a result, natural antioxidants derived from herbs and medicinal plants are continuously and thoroughly assessed to replace/minimize the application of synthetic agents during meat processing and storage. …”
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  19. 56319

    Brief exposure to (-) THC affects zebrafish embryonic locomotion with effects that persist into the next generation by Md Ruhul Amin, Lakhan Khara, Joshua Szaszkiewicz, Andrew M. Kim, Trevor J. Hamilton, Declan W. Ali

    Published 2025-01-01
    “…Abstract Cannabis is one of the most widely used drugs, and yet an understanding of its impact on the human brain and body is inconclusive. Medicinal and recreational use of cannabis has increased in the last decade with a concomitant increase in use by pregnant women. …”
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  20. 56320

    Optimization and Evaluation of <i>Cannabis</i>-Based Magistral Formulations: A Path to Personalized Therapy by Bożena Grimling, Magdalena Fast, Magdalena Okoniewska, Artur Owczarek, Bożena Karolewicz

    Published 2025-01-01
    “…Introduction: The official implementation of pharmaceutical-grade cannabis raw materials for medicinal use has permitted doctors to prescribe and pharmacists to prepare cannabis-based formulations. …”
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