From pathogenesis to new developments in treatment of primary progressive multiple sclerosis. Literature review by A. Juknelytė, Ž. Vaičekauskytė, D. Mickevičienė, R. Balnytė

“…The drug was approved in 2018 by the European Medicines Agency (EMA). Considered an incurable disease, PPMS today gives patients more hope of stopping the progression of disability. …”
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Radioscopie des territoires en Afrique à travers l’arbre (Cameroun et Burkina Faso) by Jean-Louis Yengué

“…It also provides fuel for heating, cooking and light, and is a source of medicinal products. In addition, the tree occupies an important place in the imagination of local populations and plays an essential role in agriculture. …”
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Grammatophyllum speciosum Ethanolic Extract Promotes Wound Healing in Human Primary Fibroblast Cells by Saraporn Harikarnpakdee, Verisa Chowjarean

“…Grammatophyllum speciosum is a plant in Orchidaceae family which contains a variety of phytochemical compounds that might be beneficial for medicinal use. This study aimed to evaluate the activity of pseudobulb of G. speciosum extract (GSE) in wound healing processes in human primary fibroblast cells along with in vitro antioxidant activity and total phenolic content of GSE. …”
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Does Smoking Reduce Infliximab’s Effectiveness against Crohn’s Disease? by Neeraj Narula, Richard N Fedorak

“…CD symptoms are treated using an array of medicines, including biological agents such as infliximab. …”
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Phytochemistry, Pharmacology and Toxicology of Spilanthes acmella: A Review by Suchita Dubey, Siddhartha Maity, Mahendra Singh, Shubhini A. Saraf, Sudipta Saha

“…Spilanthes acmella is an important medicinal plant, found in tropical and subtropical countries mainly India and South America. …”
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Sick Day Management for Adults with Diabetes Who Take Insulin by Nancy Gal, Linda B. Bobroff

“…This 4-page fact sheet is a major revision that discusses ways in which illness affects diabetes control, development of a sick day plan, times to call your health care provider, checking blood glucose and urine ketones, medicines, and diet. …”
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Quinazoline scaffold as a target for combating microbial resistance: Synthesis and antimicrobial profiling of quinazoline derivatives by Vishwanath Halappanavar, Sangappa Teli, Hanamant B. Sannakki, Dharyappa Teli

“…With their natural accomplishments, quinazoline derivatives have the potential to advance the development of novel antibiotics and fill the gap for potent antimicrobial drugs. Medicinal chemistry researchers seeking novel antimicrobial agents will find this evaluation valuable.…”
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Comparison between the chemical composition of essential oils isolated from biocultivated Salvia rosmarinus Spenn. (Rosmarinus officinalis L.) and some commercial products by Stanislava Ivanova, Vanya Nalbantova, Niko Benbassat, Velina Dzhoglova, Zoya Dzhakova, Nina Koleva, Veselin Vasilev, Daniela Grekova-Kafalova, Kalin Ivanov

“…(Rosmarinus officinalis L.) is an aromatic medicinal plant associated with rich phytochemical composition and significant pharmacological potential. …”
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Le bois d’aloès, « le Bois des Dieux » by Gerard A. Persoon

“…The infected wood of the Aquilaria sp. is widely used to produce incense for religious ceremonies or for pleasure but it can also be used for making perfumes or medicinal wine.Due to its high price, the harvesting of agarwood from the wild has brought the plant to the point of extinction in many areas in Vietnam, Indonesia, Laos and Malaysia. …”
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American Lotus, Yellow Lotus: Nelumbo lutea by Warner Orozco-Obando, Lyn Gettys

“…Native American tribes treated the American lotus as a sacred plant with mystical powers, and many tribes ate the large rhizomes and used parts of the plant for medicinal purposes. This 3-page fact sheet was written by Warner Orozco-Obando and Lyn Gettys, and published by the UF Department of Agronomy, March 2014. …”
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A microscale thermophoresis-based enzymatic RNA methyltransferase assay enables the discovery of DNMT2 inhibitors by Zarina Nidoieva, Mark O. Sabin, Tristan Dewald, Annabelle C. Weldert, Sabrina N. Hoba, Mark Helm, Fabian Barthels

“…Yet, most frequently utilized RNA MTase assays are limited in their throughput and hamper this rapidly evolving field of medicinal chemistry. This study developed a microscale thermophoresis (MST)-based split aptamer assay for enzymatic MTase investigations, improving current methodologies by offering a non-proprietary, cost-effective, and highly sensitive approach. …”
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Leek Cultivation Guide for Florida by Mary Dixon, Guodong Liu

“…This new 7-page publication of the UF/IFAS Horticultural Sciences Department, written by Mary Dixon and Guodong Liu, provides a basic guide to cultivation of leek in Florida, as well as information on its agricultural, culinary, and medicinal uses. https://edis.ifas.ufl.edu/hs1388 …”
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Sick Day Management for Adults with Diabetes Who Take Insulin by Nancy Gal, Linda B. Bobroff

“…This 4-page fact sheet is a major revision that discusses ways in which illness affects diabetes control, development of a sick day plan, times to call your health care provider, checking blood glucose and urine ketones, medicines, and diet. …”
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Tuning of electronic, optical and lipophilic behaviours of adamantane through various substitutions by Aravindhan R, Jianping Hu, M Ummal Momeen

“…High hydrophobicity and lipophilicity of the adamantane has a prominent application in medicinal chemistry as a lipophilic bullet for a drug. …”
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Leek Cultivation Guide for Florida by Mary Dixon, Guodong Liu

“…This new 7-page publication of the UF/IFAS Horticultural Sciences Department, written by Mary Dixon and Guodong Liu, provides a basic guide to cultivation of leek in Florida, as well as information on its agricultural, culinary, and medicinal uses. https://edis.ifas.ufl.edu/hs1388 …”
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Xanthine Oxidase: Isolation, Assays of Activity, and Inhibition by Danijela A. Kostić, Danica S. Dimitrijević, Gordana S. Stojanović, Ivan R. Palić, Aleksandra S. Đorđević, Jovana D. Ickovski

“…Several authors reported on the XO inhibitory potential of traditionally used medicinal plants.…”
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Cobalt-induced oxidative stress and defense responses of Adhatoda vasica proliferated shoots by Abeer A. Radi, Fatma A. Farghaly, Fatma A. Al-Kahtany, Ahmed M. Zaher, Afaf M. Hamada

“…We employed physiological and biochemical markers to elucidate the response mechanisms of this medicinal plant. The experiment was conducted in two replicates per treatment. …”
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Uncovering proteome variations and concomitant quality changes of different drying methods Cordyceps sinensis by 4D-DIA structural proteomics by Mengjun Xiao, Chuyu Tang, Tao Wang, Min He, Yuling Li, Xiuzhang Li

“…IntroductionCordyceps sinensis is a fungus, serves dual purposes as both a medicinal herb and a food source. Due to its high water content, fresh Cordyceps sinensis is difficult to preserve, necessitating the drying necessary to process Cordyceps sinensis.MethodsUsing 4D-DIA proteomics, researchers analyzed the proteome profiles of fresh Cordyceps sinensis (CK) under three different drying conditions: vacuum freeze-drying (FD), oven-drying (OD), and air-drying (AD). …”
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Non-invasive electroencephalogram-based anesthesiological monitoring in geriatric patients in the ent-surgery by Medhat H. Altoufaili, Tatiana V. Klypa, Irina A. Mandel, Maria S. Orekhova

“…CONCLUSION: Anesthesiology monitoring based on electroencephalogram parameters, optimizing the dosages of the medicinal agents, decreases the rates of hemodynamic disorders, of intraoperative awakenings and of postoperative nausea and vomiting. …”
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Quality assessment of fish vaccine data in the Norwegian Veterinary Prescription Register (VetReg) by Trishang Udhwani, Katharine R. Dean, Ingunn Sommerset, Kari Olli Helgesen

“…The Norwegian Veterinary Prescription Register (VetReg) is a national database that includes all prescriptions of medicines to animals dispensed by pharmacies and all medicines used for food producing animals by veterinarians. …”
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