How international research consortia can strengthen organisations’ research systems and promote a conducive environment and culture by Justin Pulford, Nadia Tagoe, Yan Ding, Imelda Bates, Susie Crossman, Taghreed El Hajj, Tara Tancred, Lorelei Silvester, Martina Savio, Natasha Bevan

“…They were partly or wholly funded by UK agencies including the Wellcome, Foreign and Commonwealth Development Office, UK Research and Innovation Fund, and the Medical Research Council and they operated for 2–10 years between 2012 and 2022.Consortia’s size and ability to access and share resources among their member organisations according to need meant they were uniquely placed to target actions to address weaknesses in member organisations’ research capacity, to widen networks and collaborations, and to build in sustainability of capacity gains. …”
Get full text

Sleep quality among sample of Egyptian patients with Alzheimer’s disease: risk factors and role of genetic profiling for ACE, ACE 2 and APO E genotypes by Khaled Ahmed Elbeh, Mohamed Abdala Abbas, Mohammed H. Hassan, Mohamed Moslem Hefny, Shimaa Fathy Sakr, Reham Bakry Mohamed, Mahmoud Ahmed Bekiet, Tarek Desoky

Get full text

Genetic association of lipid and lipid-lowing drug targets with uterine fibroids by Mei Wu, Qiannan Lin, Siyu Li, Huiyan Wang, Wenbo Zhou

Get full text

Risk of pneumonia in patients with isolated minor rib fractures: a nationwide cohort study by Yu-Hsun Wang, Ming-Chih Chou, Sai-Wai Ho, Ying-Hock Teng, Shun-Fa Yang, Han-Wei Yeh, Chao-Bin Yeh

Get full text

Engineered Perfluorochemical Cancer-Derived Exosomes Loaded with Indocyanine Green and Camptothecin Provide Targeted Photochemotherapy for Effective Cancer Treatment by Lee YH, Huang CY

“…Yu-Hsiang Lee,1– 3 Cheng-You Huang1 1Department of Biomedical Sciences and Engineering, National Central University, Taoyuan City, Taiwan, Republic of China; 2Department of Chemical and Materials Engineering, National Central University, Taoyuan City, Taiwan, Republic of China; 3Department of Medical Research, Cathay General Hospital, Taipei City, Taiwan, Republic of ChinaCorrespondence: Yu-Hsiang Lee, Department of Biomedical Sciences and Engineering, National Central University, No. 300, Jhongda Road, Taoyuan City, 320317, Taiwan, Republic of China, Tel +886-3-422-7151 Ext# 27755, Fax +886-3-280-4627, Email yuhsianl@ncu.edu.twBackground: Cancer treatments are still limited by various challenges, such as off-target drug delivery, posttreatment inflammation, and the hypoxic conditions in the tumor microenvironment; thus, the development of effective therapeutics remains highly desirable. …”
Get full text

The influence of contemporary and emerging factors on blood lead concentrations among young males in conflict with the law: a case study from a middle-income country by Thokozani P. Mbonane, Andre Swart, Angela Mathee, Angela Mathee, Nisha Naicker, Nisha Naicker

Get full text

Plant Compounds Inhibit the Growth of W12 Cervical Precancer Cells Containing Episomal or Integrant HPV DNA; Tanshinone IIA Synergizes with Curcumin in Cervical Cancer Cells by Linda Saxe Einbond, Jing Zhou, Kunhui Huang, Mario R. Castellanos, Emeka Mbazor, Michael Balick, Hongbao Ma, James A. DeVoti, Stephen Redenti, Hsan-au Wu

Get full text

Predicting Low-Risk Prostate Cancer from Transperineal Saturation Biopsies by Pim J. van Leeuwen, Amila Siriwardana, Monique Roobol, Francis Ting, Daan Nieboer, James Thompson, Warick Delprado, Anne-Marie Haynes, Phillip Brenner, Phillip Stricker

Get full text

‘With this study, we have hope that something is coming’: community members’ perceptions of HIV cure-related research in Durban, South Africa – a qualitative focus group study... by Karine Dubé, Deli Mthimkhulu, Wiseman Ngcobo, Deborah Mindry, Luyanda Maphalala, Vanessa Pillay, Whitney Tran, Ana Korolkova, Thumbi Ndung’u, Krista Dong

Get full text

Emerging PET Radiotracers and Targets for Imaging of Neuroinflammation in Neurodegenerative Diseases: Outlook Beyond TSPO by Vidya Narayanaswami PhD, Kenneth Dahl PhD, Vadim Bernard-Gauthier PhD, Lee Josephson PhD, Paul Cumming PhD, Neil Vasdev PhD

Get full text

Prevalence and Risk Factors of Human Herpes Virus Type 8 (HHV-8), Human Immunodeficiency Virus-1 (HIV-1), and Syphilis among Female Sex Workers in Malindi, Kenya by M. M. Nzivo, R. M. Lwembe, E. O. Odari, J. M. Kang’ethe, N. L. M. Budambula

Get full text

Prediction of postoperative myocardial injury in patients undergoing laparoscopic pheochromocytoma/paraganglioma resection: protocol for an ambispective cohort study by Yuguang Huang, Yuelun Zhang, Ling Lan, Yi Zhang, Ye Ma, Le Shen, Yifei Zhao, Yaohan Li

Get full text

Developing an Evidence- and Theory-Informed Mother-Daughter mHealth Intervention Prototype Targeting Physical Activity in Preteen Girls of Low Socioeconomic Position: Multiphase Co... by Carol Brennan, Grainne ODonoghue, Alison Keogh, Ryan E Rhodes, James Matthews

“…MethodsThe intervention prototype was developed in accordance with the United Kingdom Medical Research Council framework, the Behaviour Change Wheel, the Theoretical Domains Framework, and the Behaviour Change Techniques Ontology. …”
Get full text

CD40 Gene Polymorphisms Associated with Susceptibility and Coronary Artery Lesions of Kawasaki Disease in the Taiwanese Population by Ho-Chang Kuo, Mei-Chyn Chao, Yu-Wen Hsu, Ying-Chi Lin, Ying-Hsien Huang, Hong-Ren Yu, Ming-Feng Hou, Chi-Di Liang, Kuender D. Yang, Wei-Chiao Chang, Chih-Lu Wang

Get full text

Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trial by Xue Gao, Lu Liu, Mei-Rong Pan, Hai-Mei Li, Yu-Feng Wang, Xue-Ying Liu, Zhong-Fang Fu, Qiujin Qian

“…The findings may contribute to providing an effective and feasible transdiagnostic intervention in Chinese clinical settings.Ethics and dissemination This trial has been approved by the Ethics and Clinical Research Committees of Peking University Sixth Hospital and will be performed under the Declaration of Helsinki with the Medical Research Involving Human Subjects Act (WMO). The results will be disseminated in a peer-reviewed journal and a conference presentation.Trial registration number ChiCTR2300069354.…”
Get full text

Primary ciliary dyskinesia: Meeting the challenges of diagnosis in South Africa by Z Dangor, M Birkhead, C Verwey, D Gray, A Vanker, L Githinji, A Goga, R Masekela, M Zampoli

Get full text

Public assistance in patients with acute heart failure: a report from the KCHF registry by Yuji Nishimoto, Takao Kato, Takeshi Morimoto, Ryoji Taniguchi, Hidenori Yaku, Yasutaka Inuzuka, Yodo Tamaki, Erika Yamamoto, Yusuke Yoshikawa, Takeshi Kitai, Moritake Iguchi, Masashi Kato, Mamoru Takahashi, Toshikazu Jinnai, Tomoyuki Ikeda, Kazuya Nagao, Takafumi Kawai, Akihiro Komasa, Ryusuke Nishikawa, Yuichi Kawase, Takashi Morinaga, Kanae Su, Mitsunori Kawato, Yuta Seko, Moriaki Inoko, Mamoru Toyofuku, Yutaka Furukawa, Yoshihisa Nakagawa, Kenji Ando, Kazushige Kadota, Satoshi Shizuta, Koh Ono, Koichiro Kuwahara, Neiko Ozasa, Yukihito Sato, Takeshi Kimura

Get full text

Bioinspired hierarchical porous tough adhesive to promote sealing of high-pressure bleeding by Yinghao Li, Dongling Xiao, Weixi Yan, Meilin Jiang, Ju Tan, Zhongliang Qin, Jingting Zhou, Yue Sun, Mingcan Yang, Guanyuan Yang, Yawei Gu, Yong Liu, Chuhong Zhu

Get full text

AI-based tumor-infiltrating lymphocyte scoring system for assessing HCC prognosis in patients undergoing liver resection by Zhiyang Chen, Tingting Xie, Shuting Chen, Zhenhui Li, Su Yao, Xuanjun Lu, Wenfeng He, Chao Tang, Dacheng Yang, Shaohua Li, Feng Shi, Huan Lin, Zipei Li, Anant Madabhushi, Xiangtian Zhao, Zaiyi Liu, Cheng Lu

Get full text

The phosphorus negotiation game (P-Game): first evaluation of a serious game to support science-policy decision making played in more than 20 countries worldwide by Nils Haneklaus, Mary Kaggwa, Jane Misihairabgwi, Sherif Abu El-Magd, Naima Ahmadi, Jamal Ait Brahim, Aloyce Amasi, Andrea Balláné Kovács, Łukasz Bartela, Hajar Bellefqih, Redouane Beniazza, Jaroslav Bernas, Essaid Bilal, Tomislav Bituh, Yelizaveta Chernysh, Viktoriia Chubur, Jelena Ćirić, Claudia Dolezal, Andrea Figulová, Janja Filipi, Gordana Glavan, Tibor Guzsvinecz, László Horváth, Sasho Josimovski, Martin Kiselicki, Maja Lazarus, Maja Kazazić, István Komlósi, Ali Maged, Tebogo Mashifana, Gordana Medunić, Emina Mehić, Felhi Mongi, Kelvin Mtei, Dennis Mwalongo, Jerome Mwimanzi, Jakub Nowak, Oqba Basal, Khaoula Qamouche, Małgorzata Rajfur, Hynek Roubík, Mijalche Santa, Cecília Sik-Lányi, Maike Sippel, Gerald Steiner, Anna Skorek-Osikowska, Anton Slavov, Paweł Świsłowski, Ali Tlili, Kalina Trenevska-Blagoeva, Ivan Tschalakov, Tomáš Vlček, Stanisław Wacławek, Ivan Zlatanović, Matúš Mišík, Hendrik Brink, Tzong-Ru Lee

Get full text