Smoking as a risk factor for lung cancer in women and men: a systematic review and meta-analysis by Sanne A E Peters, Mark Woodward, Paul Mitchell, Rachel R Huxley, Gemma Taylor, Linda M O’Keeffe

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Geospatial mapping of drug-resistant tuberculosis prevalence in Africa at national and sub-national levels by Alemneh Mekuriaw Liyew, Archie C.A. Clements, Fasil Wagnew, Beth Gilmour, Kefyalew Addis Alene

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Help-seeking for depression among Vietnamese migrant workers in Japan and factors related to their intentions to seek help from a psychiatrist: a cross-sectional study by Yui Fukuda, Atsuko Taguchi, Akane Futami, Yusuke Umegaki, Pham Nguyen Quy, Toshihiko Nakajima, Akihito Uezato

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Predicting the effects of introducing an emergency transport system in low-income and middle-income countries: a spatial-epidemiological modelling study by Justine Davies, Dmitri Nepogodiev, Stephen Tabiri, Richard Lilford, Srinivasa Vittal Katikireddi, Samuel I Watson, Katie Scandrett

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Deprescribing and Optimal Selection of Proton Pump Inhibitors (Contributions of the 26th United Russian Gastroenterology Week) by V. T. Ivashkin, I. V. Maev, A. S. Trukhmanov, A. A. Sheptulin, V. I. Simanenkov, T. L. Lapina, I. B. Khlynov, N. N. Dekhnich, O. D. Lopina, O. P. Alekseeva, N. V. Korochanskaya, M. F. Osipenko, P. V. Pavlov, S. S. Pirogov, G. N. Tarasova, Yu. P. Uspenskiy, D. N. Andreev, D. E. Rumyantseva

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Heat transfer enhancement inside a constant temperature pipe via clockwise and counter-clockwise twisted triangle turbulators, applicable in IC engine system by Hongliang Wang, Azher M. Abed, Pinank Patel, Nagaraj Patil, Hamdi Ayed, Abir Mouldi, Ibrahim Mahariq

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Coffee, including caffeinated and decaffeinated coffee, and the risk of hepatocellular carcinoma: a systematic review and dose–response meta-analysis by Paul Roderick, Peter Clive Hayes, Julie Parkes, Ryan Buchanan, Oliver John Kennedy, Jonathan Andrew Fallowfield

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Limited Vitrectomy versus Complete Vitrectomy for Epiretinal Membranes: A Comparative Multicenter Trial by Matteo Forlini, Purva Date, Domenico D’Eliseo, Paolo Rossini, Adriana Bratu, Andrea Volinia, Giovanni Neri, Tommaso Verdina, Maria Rosaria Carbotti, Gian Maria Cavallini, Luigi Sborgia, Alessandra Galeone, Aurelio Imburgia, Alessandro Mularoni, Alessandro Meduri

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Interferon-γ production in response to the cytotoxic T lymphocyte epitope within an antigen incorporated in simian virus 40 virus-like particles by Takeharu Watanabe, Masayuki Hayashi, Masaaki Arai, Sho Matsushita, Hiroshi Handa, Masaaki Kawano

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Self-Harm in Eating Disorders (SHINE): a mixed-methods exploratory study by Maria Michail, Helen Bould, Anna Lavis, Sheryllin McNeil, Anthony Winston, Kalen Reid, Christina L Easter, Rosina Pendrous

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Experience of Kenyan researchers and policy-makers with knowledge translation during COVID-19: a qualitative interview study by Edwine Barasa, Benjamin Tsofa, Mike English, Sassy Molyneux, Dorcas Mwikali Kamuya, Fatuma Hassan Guleid, Alex Njeru, Joy Kiptim, Emelda Okiro, David Kariuki

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Effects of cardiovascular health, musculoskeletal health and physical fitness on occupational performance of firefighters: protocol for a systematic review and meta-analysis by Andre Pascal Kengne, Denise Smith, Jaron Ras, Elpidoforos Soterakis Soteriades, Lloyd Leach

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TLR4/AP-1-Targeted Anti-Inflammatory Intervention Attenuates Insulin Sensitivity and Liver Steatosis by Xiang Hu, Jing Zhou, Sha-sha Song, Wen Kong, Yan-Chuan Shi, Lu-Lu Chen, Tian-Shu Zeng

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Translational Science in Vascular Aging: From Bench to Bedside—Insights from a VascAgeNet Roundtable by Elisabetta Bianchini, Lynn Roth, Pierre Boutouyrie, Smriti Badhwar, Achim Schwarz, Vincenzo Gemignani, Rosa Maria Bruno, Bernhard Hametner, Chloe Park, Giacomo Pucci, Ioana Mozos, Dimitrios Terentes-Printzios, Rachel E. Climie, Andrea Guala, Jordi Alastruey, Christopher C. Mayer

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Protocol of a parallel group Randomized Control Trial (RCT) for Mobile-assisted Medication Adherence Support (Ma-MAS) intervention among Tuberculosis patients. by Zekariyas Sahile, Lua Perimal-Lewis, Paul Arbon, Anthony John Maeder

“…<h4>Discussion</h4>For this trial, a mobile-assisted medication adherence intervention will first be developed systematically based on the Medical Research Council framework using appropriate behavioural theory and evidence. …”
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Integrating in vitro and in silico techniques for evaluating the antioxidant activity of Chrysanthemum indicum L by Fatimawali, Billy J. Kepel, Linda W. A. Rotty, Trina E. Tallei, Fahrul Nurkolis

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RECK as a Potential Crucial Molecule for the Targeted Treatment of Sepsis by Qin Y, Liao S, Sun J, Ye H, Li J, Pan J, He J, Xia Z, Shao Y

“…Yuting Qin,1,&ast; Shuanglin Liao,1,&ast; Jianbo Sun,2 Huiyun Ye,1 Jiafu Li,1 Jiahui Pan,1 Junbing He,3 Zhengyuan Xia,4,5 Yiming Shao1,6 1Dongguan Key Laboratory of Sepsis Translational Medicine, The Intensive Care Unit, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong, People’s Republic of China; 2Dongguan Key Laboratory of Chronic Inflammatory Diseases, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong, People’s Republic of China; 3The Key Laboratory of Organ Dysfunction and Protection Translational Medicine, Jieyang Medical Research Center, Jieyang People’s Hospital, Jieyang, Guangdong, People’s Republic of China; 4Department of Anesthesiology and Perioperative Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, People’s Republic of China; 5State Key Laboratory of Pharmaceutical Biotechnology, Department of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, People’s Republic of China; 6The Key Laboratory of Sepsis Translational Medicine, Guangdong Medical University, Zhanjiang, Guangdong, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yiming Shao, Dongguan Key Laboratory of Sepsis Translational Medicine, the Intensive Care Unit,The First Dongguan Affiliated Hospital, Guangdong Medical University, Jiaoping Road 42, Tangxia Town, Dongguan, Guangdong Province, 523710, People’s Republic of China, Tel +86 18826690188, Email sym@gdmu.edu.cn Zhengyuan Xia, Department of Anesthesiology and Perioperative Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, People’s Republic of China, Tel +852-68798794, Email zyxia@hku.hkAbstract: Reversion inducing cysteine rich protein with kazal motifs (RECK), a Kazal motif-containing protein, regulates pro-inflammatory cytokines production, migration of inflammatory cells, vascular endothelial growth factor (VEGF) and Wnt pathways and plays critical roles in septic inflammatory storms and vascular endothelial dysfunction. …”
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Infusion of Autologous Retrodifferentiated Stem Cells into Patients with Beta-Thalassemia by Ilham Saleh Abuljadayel, Tasnim Ahsan, Huma Quereshi, Shakil Rizvi, Tamseela Ahmed, Sabiha Mirza Khan, Jawaid Akhtar, Ghazi Dhoot

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Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications by Pharaoh Fellow Mwale, Cheng-Ta Hsieh, Ting-Lin Yen, Jing-Shiun Jan, Rajeev Taliyan, Chih-Hao Yang, Wen-Bin Yang

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Targeting Cytokine-Mediated Inflammation in Brain Disorders: Developing New Treatment Strategies by Rahul Mallick, Sanjay Basak, Premanjali Chowdhury, Prasenjit Bhowmik, Ranjit K. Das, Antara Banerjee, Sujay Paul, Surajit Pathak, Asim K. Duttaroy

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