Exploring Long Noncoding RNAs in Glioblastoma: Regulatory Mechanisms and Clinical Potentials by Tao Zeng, Lei Li, Yan Zhou, Liang Gao

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Nucleus pulposus cell network modelling in the intervertebral disc by Sofia Tseranidou, Maria Segarra-Queralt, Francis Kiptengwer Chemorion, Christine Lyn Le Maitre, Janet Piñero, Jérôme Noailly

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The Relation between Periodontopathogenic Bacterial Levels and Resistin in the Saliva of Obese Type 2 Diabetic Patients by Natheer Al-Rawi, Farah Al-Marzooq

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Tribute to Michael O’Rourke (1937–2024): A Collective Tribute to a Colleague, Friend and Mentor by Alberto Avolio, Barry Gow, Wilmer Nichols, Dean Winter, Christopher Hayward, David Gallagher, John Cockcroft, Audrey Adji, Junichiro Hashimoto, Charalambos Vlachopoulos

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Genetic screening of South African families with Parkinson’s disease by S Bardien, A Braun, R van Coller, F Hassan Amod, J Carr, S Moosa

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Developmental Perturbation Induced by Maternal Asthma during Pregnancy: The Short- and Long-Term Impacts on Offspring by Vicki L. Clifton, Michael Davies, Vivienne Moore, Ian M. R. Wright, Zainab Ali, Nicolette A. Hodyl

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Role of PPARα and Its Agonist in Renal Diseases by Ching-Feng Cheng, Hsi-Hsien Chen, Heng Lin

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The Utah Population Database. The Legacy of Four Decades of Demographic Research by Ken. R. Smith, Geraldine P. Mineau

“…This paper summarizes the unique characteristics of the Utah Population Database (UPDB) and how it has catalyzed demographic, social and medical research since the mid-1970s. The UPDB is one of the world’s richest sources of linked population-based information for demographic, genetic, and epidemiological studies at the Individual-level. …”
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Microgravity and Cardiovascular Health in Astronauts: A Narrative Review by John Azariah, Umberto Terranova

“…ABSTRACT Background Space exploration has become a major interest for scientific and medical research. With increasing duration and frequency of manned space missions, it is crucial to understand the impact of microgravity on the cardiovascular health of astronauts. …”
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Modern Approaches in the Morphological Diagnosis of Inflammatory Bowel Diseases by A. S. Tertychnyy, Kh. M. Akhriyeva, E. A. Kogan, O. V. Zayratyants, L. S. Selivanova

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Preclinical advance in nanoliposome-mediated photothermal therapy in liver cancer by Lixuan Tang, Xiao Yang, Liwen He, Chaogeng Zhu, Qingshan Chen

“…Therefore, its treatment has long been a focus of medical research. Although traditional treatment methods such as surgery, radiotherapy, and chemotherapy have increased the survival rate of patients, their efficacy remains unsatisfactory owing to the nonspecific distribution of drugs, high toxicity, and drug resistance of tumor tissues. …”
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Antimicrobial Analysis of Biosynthesized Lectin-Conjugated Gold Nanoparticles by Hassien M. Alnashiri, Fahad M. Aldakheel, Abdulkarim S. Binshaya, Nahed S. Alharthi, Musthaq Ahmed

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Apigenin inhibits NLRP3 inflammasome activation in monocytes and macrophages independently of CD38 by Knut Husø Lauritzen, Knut Husø Lauritzen, Kuan Yang, Michael Frisk, Mieke C. Louwe, Maria Belland Olsen, Maria Belland Olsen, Mathias Ziegler, William E. Louch, Bente Halvorsen, Bente Halvorsen, Pål Aukrust, Pål Aukrust, Arne Yndestad, Øystein Sandanger, Øystein Sandanger

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Associations Between Complement C4, Habitual Constipation, and Sleep Disturbance in Oldest-Old and Centenarian Chinese Adults by Sun Z, Nie Y, Pei J, Gao M, Luan Z, Zhao Y, Li Z, Fu S

“…Zhigao Sun,1,* Yan Nie,2,* Jianqiu Pei,3,* Ming Gao,4,* Zhe Luan,5,* Yali Zhao,6 Zhaoxing Li,7 Shihui Fu8,9 1Traditional Chinese Medicine Department, Hainan Hospital of Chinese People’s Liberation Army General Hospital, Sanya, People’s Republic of China; 2Department of Gastroenterology, Hainan Hospital of Chinese People’s Liberation Army General Hospital, Sanya, People’s Republic of China; 3Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Capital Medical University, Beijing, People’s Republic of China; 4School of Engineering Medicine, Beihang University, Beijing, People’s Republic of China; 5Department of Gastroenterology and Hepatology, The First Medical Center of Chinese People’s Liberation Army General Hospital, Beijing, People’s Republic of China; 6Central Laboratory, Hainan Hospital of Chinese People’s Liberation Army General Hospital, Sanya, People’s Republic of China; 7Department of General Surgery, The Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of China; 8Department of Cardiology, Hainan Hospital of Chinese People’s Liberation Army General Hospital, Hainan Geriatric Disease Clinical Medical Research Center, Hainan Branch of China Geriatric Disease Clinical Research Center, Sanya, People’s Republic of China; 9Department of Geriatric Cardiology, Chinese People’s Liberation Army General Hospital, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhaoxing Li, Department of General Surgery, The Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of China, Email lizhaoxing1984@hebmu.edu.cn Shihui Fu, Department of Cardiology, Hainan Hospital of Chinese People’s Liberation Army General Hospital, Hainan Geriatric Disease Clinical Medical Research Center, Hainan Branch of China Geriatric Disease Clinical Research Center, Sanya, People’s Republic of China, Email xiaoxiao0915@126.comBackground: Sleep disturbance is an immune-related disease, and the gut–brain axis is an important regulatory pathway. …”
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Pharmacological Evaluation of Secondary Metabolites and Their Simultaneous Determination in the Arabian Medicinal Plant Plicosepalus curviflorus Using HPTLC Validated Method by Raha Orfali, Shagufta Perveen, Nasir Ali Siddiqui, Perwez Alam, Tawfeq Abdullah Alhowiriny, Areej Mohammad Al-Taweel, Sami Al-Yahya, Fuad Ameen, Najwa Majrashi, Khulud Alluhayb, Bandar Alghanem, Hayat Shaibah, Shabana Iqrar Khan

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Urine miRNA signature as potential non-invasive diagnostic biomarker for Hirschsprung’s disease by Abhijit Sreepada, Abhijit Sreepada, Rasul Khasanov, Enas Zoheer Elkrewi, Enas Zoheer Elkrewi, Carolina de la Torre, Judith Felcht, Ahmad A. Al Abdulqader, Ahmad A. Al Abdulqader, Richard Martel, Nicolás Andrés Hoyos-Celis, Michael Boettcher, Lucas M. Wessel, Karl-Herbert Schäfer, María Ángeles Tapia-Laliena

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Extensive Inactive Neurocysticercosis: A Case Report in Mbeya, Southern Highlands of Tanzania by Makasi CE, Ngowi BJ, Stelzle D, Kilale AM, Mahande MJ, Welte TM, Winkler AS, Mmbaga BT

“…Charles Elias Makasi,1,2 Bernard James Ngowi,3 Dominik Stelzle,4 Andrew Martin Kilale,1 Michael Johnson Mahande,2,5 Tamara Margarete Welte,4 Andrea Sylvia Winkler,4,6 Blandina Theophil Mmbaga2,7 1National Institute for Medical Research, Muhimbili Medical Research Centre, Dar Es Salaam, Tanzania; 2Kilimanjaro Christian Medical University College of Tumaini University, Moshi, Tanzania; 3University of Dar Es Salaam, Mbeya College of Health and Allied Sciences, Mbeya, Tanzania; 4Department of Neurology and Center for Global Health, School of Medicine and Health, Technical University Munich, Munich, Germany; 5Department of Epidemiology and Biostatistics, Institute of Public Health, Kilimanjaro Christian Medical University College, Moshi, Tanzania; 6Department of Community Medicine and Global Health, Institute of Health and Society, University of Oslo, Oslo, Norway; 7Kilimanjaro Clinical Research Institute, Kilimanjaro Christian Medical Centre, Moshi, TanzaniaCorrespondence: Charles Elias Makasi, Email charlesemakasi@gmail.comBackground: Neurocysticercosis (NCC) and Acquired Human Immunodeficiency Syndrome (AIDS) are both highly prevalent in Africa. …”
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Iterative delivery of an implementation support package to increase and sustain the routine provision of antenatal care addressing alcohol consumption during pregnancy: study proto... by John Attia, Luke Wolfenden, Nicole Nathan, Melanie Kingsland, Olivia Wynne, Penny Reeves, Alix Hall, John Wiggers, Elizabeth J Elliott, Tameka McFadyen, Tracey W Tsang, Emma Doherty, Belinda Tully, Adrian John Dunlop, Ian Symonds

“…Economic and process evaluation measures will also be reported.Ethics and dissemination Ethical approval was obtained through the Hunter New England (16/11/16/4.07, 16/10/19/5.15) and University of Newcastle Human Research Ethics Committees (H-2017-0032, H-2016-0422) and the Aboriginal Health and Medical Research Council (1236/16). Trial findings will be disseminated to health service decision makers to inform the feasibility of conducting additional cycles to further improve antenatal care addressing alcohol consumption as well as at scientific conferences and in peer-reviewed journals.Trial registration number Australian and New Zealand Clinical Trials Registry (ACTRN12622000295741).…”
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Polypharmacy and self-medication among older adults in Indian urban communities—a cross-sectional study by Saibal Das, Pavithra Gnanavel, Shalini Smanla, Anku Moni Saikia, Shilpi Mishra, Shweta Khare, S. Arun Murugan, Vadanere Nidhi Prakash, Parimita Roychoudhury, Ishteyaque Ahmad, Vishal Diwan, J. Rajesh, K. Sathish Kumar, Jugal Kishore, Namita Srivastava, Sabrina Yasmin, Mahmuda Nasrin, Rinku Borah, Mandeep Sarma Basistha, Chetanjit Baruah, Manoj Kalita, Shambo Samrat Samajdar, Jerin Jose Cherian, Ashish Pathak, Samiran Panda, Santanu Kumar Tripathi, Cecilia Stålsby Lundborg

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Vic9 mycobacteriophage: the first subcluster B2 phage isolated in Russia by Marina Zaychikova, Maja Malakhova, Dmitry Bespiatykh, Maria Kornienko, Ksenia Klimina, Aleksandra Strokach, Roman Gorodnichev, Arina German, Mikhail Fursov, Dmitry Bagrov, Dmitry Bagrov, Anna Vnukova, Alexandra Gracheva, Anastasia Kazyulina, Margarita Shleeva, Egor Shitikov

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