Protocol for an intervention development and pilot implementation evaluation study of an e-health solution to improve newborn care quality and survival in two low-resource settings... by Hassan Haghparast-Bidgoli, Michelle Heys, Caroline Crehan, Erin Kesler, Monica Lakhanpaul, Emma Wilson, Fabiana Lorencatto, Felicity Fitzgerald, Mario Cortina Borja, Msandeni Chiume, Hannah Gannon, Simbarashe Chimhuya, Gwendoline Chimhini, Tim Hull-Bailey, Tarisai Chiyaka, Yali Sassoon, Deliwe Nkhoma, Nushrat Khan, Alexander G. Stevenson, Kristina Curtis

“…Research ethics approvals have been obtained: Malawi College of Medicine Research and Ethics Committee (P.01/20/2909; P.02/19/2613); UCL (17123/001, 6681/001, 5019/004); Medical Research Council Zimbabwe (MRCZ/A/2570), BRTI and JREC institutional review boards (AP155/2020; JREC/327/19), Sally Mugabe Hospital Ethics Committee (071119/64; 250418/48). …”
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Tracking acute flaccid paralysis in Niger: a half-decade epidemiological portrait (2016–2021) by El Khalef Ishagh, Marc Talatou Ouédraogo, Batouré Oumarou, Mutenda Sheria Kaya, Gbaguidi Aichatou Diawara, Abdoulaye Macire Camara, Seyni Moussa, Kuyangisa Bienvenu, Joseph Toko, Hamidou Harouna, Haladou Moussa, N.’Zue Kofi, Jacques L. Tamuzi, Patrick D. M. C. Katoto, Charles S. Wiysonge, Blanche-Philomene Melanga Anya, Manengu Casimir Tshikolasoni

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miR-1458 is inhibited by low concentrations of Vitamin B6 and targets TBX6 to promote the formation of spermatogonial stem cells in Rugao Yellow Chicken by Qingqing Geng, Cai Hu, Ziduo Zhao, Zhe Wang, Fufu Cheng, Jing Chen, Qisheng Zuo, Yani Zhang

“…Spermatogonial stem cells (SSCs) have vast application prospects in livestock and poultry production, genetic engineering, and medical research. However, the scarcity of SSCs and the complexity of their development limit the elucidation and verification of the mechanism of SSCs in vitro. …”
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Long-Term Safety of Ixekizumab Treatment in Patients with Psoriasis, Psoriatic Arthritis, or Axial Spondyloarthritis: a Post Hoc Analysis of Cerebro-Cardiovascular Events by Mark Lebwohl, Atul Deodhar, Sergio Schwartzman, Carlo Salvarani, Meghan Feely McDonald, Natalia Bello, Elsie L. Grace, Elsa Inman, Andris Kronbergs, Marcus Ngantcha, Proton Rahman, Kim A. Papp, Joseph F. Merola, Alice B. Gottlieb, Andrew Blauvelt

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plaTform fOr Urinary tract infection diagnostiC evAluatioN (TOUCAN): a protocol for a prospective diagnostic accuracy study of point-of-care testing in patients suspected of acute... by Thomas R Fanshawe, Philip J Turner, Gail N Hayward, Margaret Glogowska, Alastair D Hay, Michael Moore, Mark Lown, Christopher C Butler, Mandy Wootton, Mark H Wilcox, Jane Freeman, Nicola Kenealy, Valerie Tate, Owain Llion, Rebecca Lowe

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Socioeconomic indicators related to the global burden of breast cancer in women in 2020: an analysis of WHO data by Tingting XU, Ruoyu YANG, Jingjing LI, Yiying FANG

“…The mean values of the 10 selected indicators representing national socioeconomic development were as follows: 2 138.06 ± 7 465.03 million for total female population, 26.58 ± 17.12 μg/m3 for mean annual urban particulate matter concentration; 63.97 ± 57.32 per 10 000 population for density of physicians, 4.01 ± 4.11 per 10 000 population for density of pharmacists, 4.11 ± 4.32 US dollars for net official development assistance received by the medical research and basic health sector per capita, 63.65 ± 20.31 for average of 13 International Health Regulations Core Capacity Scores, 10. 41 ± 5.17% for the percentage of government health expenditure, 68.00 ± 28.65% for the percentage of the population using safely managed sanitation services, 66.05 ± 95.28 million US dollars in official development assistance (ODA) provided through government-coordinated expenditure plans specifically for water and sanitation, and 0.587 ± 0.190 for the inequality-adjusted Human Development Index (HDI). …”
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Development of a new nanobiotechnology method for the differential diagnosis of ocular adnexal tumors by S.V. Saakyan, D.A. Skladnev, A.P. Alekseeva, O.V. Beznos, V.V. Sorokin

“…Sorokin² </p> <p> ¹Helmholtz National Medical Research Center, Moscow, Russian Federation </p> <p> ²Federal Research Center "Fundamental Basis of Biotechnology", Moscow, Russian Federation </p> <p> <b>Aim: </b>to develop a new nanobiotechnology method for the differential diagnosis of ocular adnexal tumors. …”
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Managing cognitive impairment in patients with chronic obstructive pulmonary disease (COPD) in Saudi Arabia: what are the current practices? by Rayan A. Siraj, Ahmed M. Alrajeh, Mushabbab A. Alahmari, Fahad H. Alahmadi, Abdulelah M. Aldhahir, Abdullah A. Alqarni, Jaber S. Alqahtani, Saeed M. Alghamdi, Turki M. Alanazi, Abdullah Alruwaili, Saleh S. Algarni, Abdulrhman S. Alghamdi, Tawah H. Alsindi, Mohammed M. Alyami, Faisal A. Alshehri, Talal Alshammari, Rehab Alhasani, Khalid Alrashed, Nawaf E. Sabir, Ataa F. Mesbah

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Water, sanitation, handwashing, and nutritional interventions can reduce child antibiotic use: evidence from Bangladesh and Kenya by Ayse Ercumen, Andrew N. Mertens, Zachary Butzin-Dozier, Da Kyung Jung, Shahjahan Ali, Beryl S. Achando, Gouthami Rao, Caitlin Hemlock, Amy J. Pickering, Christine P. Stewart, Sophia T. Tan, Jessica A. Grembi, Jade Benjamin-Chung, Marlene Wolfe, Gene G. Ho, Md. Ziaur Rahman, Charles D. Arnold, Holly N. Dentz, Sammy M. Njenga, Theodora Meerkerk, Belinda Chen, Maya Nadimpalli, Mohammad Aminul Islam, Alan E. Hubbard, Clair Null, Leanne Unicomb, Mahbubur Rahman, John M. Colford, Stephen P. Luby, Benjamin F. Arnold, Audrie Lin

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Attitudes toward scale-up of an Intensive Combination Approach to Rollback the Epidemic in Nigerian adolescents (iCARE) intervention for youth in Nigeria: results of a mixed method... by Arthi Kozhumam, Revika Singh, Oche Agbaji, Adedotun Adetunji, Bopo Taiwo, Olayinka Omigbodun, Kehinde Kuti, Agatha David, Sulaimon Akanmu, Folashade Adekambi, Akinsegun Akinbami, Bibilola Oladeji, Babafemi Taiwo, Lisa M. Kuhns, Ogochukwu Okonkwor, Baiba Berzins, Amy K. Johnson, Titilope Badru, Patrick Janulis, Olubusuyi M. Adewumi, Marbella Cervantes, Olutosin Awolude, Robert Garofalo, Aima A. Ahonkhai, Lisa R. Hirschhorn

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Ascorbic acid-containing compound efficacy in ischemic brain damage by Rita M. Termulaeva, Konstantin Y. Belanov, Natalya D. Bunyatyan, Aleksander S. Pirozhkov, Dmitrii E. Timoshkin, Ekaterina V. Blinova, Olga V. Vasilkina, Kirill D. Blinov, Elena V. Semeleva, Aleksander A. Dmitriev, Dmitrii S. Blinov

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Numerical simulation of Stephan blowing impacts on thermally laminated 3D flow of MHD trihybrid nanofluid with Soret and Dufour effects by Noureddine Elboughdiri, Munawar Abbas, Hamdi Ayed, Abir Mouldi, Nahid Fatima, Dilsora Abduvalieva, Mohamed Said, Ibrahim Mahariq, Ahmed S. Hendy, Ahmed M. Galal

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Hippocampal connectivity dynamics and volumetric alterations predict cognitive status in migraine: A resting-state fMRI study by Seyda Cankaya, Behcet Ayyildiz, Dila Sayman, Umutcan Duran, Dogukan Ucak, Ramazan Karaca, Sevilay Ayyildiz, Ece Ozdemir Oktem, Hatice Lakadamyalı, Ceyhun Sayman, Ahmet Ozsimsek, Ali Yalçınkaya, Lutfu Hanoglu, Halil Aziz Velioglu, Burak Yulug

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Epidemiological aspects of nephrolithiasis and chronic diseases of the cardiovascular system combination by R. V. Royuk, S. K. Yarovoy, N. A. Guseva, Sh. L. Voskanyan, V. V. Royuk, D. B. Rodin

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Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlle... by Jeremy Chataway, Suvankar Pal, Charis Wong, Elizabeth Elliott, Jenna M Gregory, Siddharthan Chandran, Judith Newton, Shuna Colville, Maria Stavrou, Christopher J Weir, Nigel Stallard, Malcolm R Macleod, Michelle Steven, Richard Anthony Parker, Arpan R Mehta, Robert J Swingler, Mahesh K B Parmar, Rachel S Dakin, Jill Williamson

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Improving community-based first response to out of hospital cardiac arrest (FirstCPR): protocol for a cluster randomised controlled trial by Sandra Ware, Blake Angell, Julie Redfern, Clara Chow, Cate Ferry, Lee Taylor, Christopher Semsarian, Adrian Bauman, Janet E Bray, Simone Marschner, Michael Nelson, Saurabh Kumar, Matthew Vukasovic, Kevin Lai, Paul M Middleton, Pramesh Kovoor, Garry Jennings, Sonali Munot, Andrew Coggins, Alan Robert Denniss, Sarah Khanlari, Ian Opperman

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Microbial community variations in adult Hyalomma dromedarii ticks from single locations in Saudi Arabia and Tunisia by Myriam Kratou, Apolline Maitre, Apolline Maitre, Apolline Maitre, Lianet Abuin-Denis, Lianet Abuin-Denis, Rachid Selmi, Hanène Belkahia, Abdullah D. Alanazi, Hattan Gattan, Hattan Gattan, Bassam M. Al-Ahmadi, Abdullah F. Shater, Lourdes Mateos-Hernández, Dasiel Obregón, Lilia Messadi, Alejandro Cabezas-Cruz, Mourad Ben Said, Mourad Ben Said

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Importance of EQA/PT for the detection of genetic variants in comprehensive cancer genome testing by Kazuyuki Matsushita, Takayuki Ishige, Kousuke Watanabe, Toshiaki Akahane, Akihide Tanimoto, Michiko Yoshimoto, Munekazu Yamakuchi, Teruto Hashiguchi, Yoshinaga Okugawa, Makoto Ikejiri, Toshikazu Yamaguchi, Tadashi Yamasaki, Mayu Takeda, Masaaki Hibi, Naoki Akiyama, Kaho Shimizu, Naonori Hashimoto, Hiroko Sato, Yoshinori Tanaka, Fumie Amari, the EQA working group of Japan Association for Clinical Laboratory Science(JACLS)

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Atezolizumab, bevacizumab, pemetrexed and platinum for EGFR‐mutant NSCLC patients after EGFR TKI failure: A phase II study with immune cell profile analysis by Shang‐Gin Wu, Chao‐Chi Ho, James Chih‐Hsin Yang, Shu‐Han Yu, Yen‐Feng Lin, Shu‐Chin Lin, Bin‐Chi Liao, Ching‐Yao Yang, Yen‐Ting Lin, Chong‐Jen Yu, Ya‐Ting Chuang, Wei‐Yu Liao, Kah Yi Yap, Weng Si Kou, Jin‐Yuan Shih

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DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells by Ignacio Melero, Ruth Conde-Garrosa, David Sancho, Santos Mañes, Alfonso R Sanchez-Paulete, Francisco J Cueto, Carlos del Fresno, Paola Brandi, Alexis J. Combes, Elena Hernández-García, Michel Enamorado, Christian P Bromley, Manuel J Gomez, Santiago Zelenay, Salvador Iborra, Matthew F. Krummel

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