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Decreased Expression of Thyroglobulin and Sodium Iodide Symporter Genes in Hashimoto’s Thyroiditis
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Investigation of the Protective Effects of Dexmedetomidine, Midazolam, Propofol, and Intralipid on Oxidative Stress and Inflammation in Rats with Lidocaine-Induced Toxicity
Published 2025-01-01“…Mustafa Kemal Kucun,1 Eray Metin Guler,2,3 Ayten Saracoglu,4 Mehmet Yildirim,5 Cumaali Demirtas,5 Ferda Serdogan,6 Hakan Beyaztas,2,7 Selman Aktas,8 Merve Kacan,9 Tomasz Gaszynski,10 Pawel Ratajczyk,10 Kemal Tolga Saracoglu11 1Department of Anesthesiology and Intensive Care, Bartin State Hospital, Bartin, Turkey; 2Department of Medical Biochemistry, Hamidiye Faculty of Medicine, University of Health Sciences Turkey, Istanbul, Türkiye; 3Department of Medical Biochemistry, Hamidiye Institute of Health Sciences, University of Health Sciences Turkey, Istanbul, Türkiye; 4Department of Anesthesiology, ICU & Perioperative Medicine Aisha Bint Hamad Al Attiyah Hospital HMC, Doha, Qatar; 5Department of Physiology, Hamidiye Faculty of Medicine, University of Health Sciences, Istanbul, Turkey; 6Department of Anesthesiology and Intensive Care, Turhal State Hospital, Tokat, Turkey; 7Department of Medical Biochemistry, HaydarpasaNumune Health Application and Research Center, University of Health Sciences Turkey, Istanbul, Türkiye; 8University of Health Sciences, Hamidiye Faculty of Medicine, Department of Biostatistics and Medical Informatics, Istanbul, Turkey; 9Department of Anesthesiology and Intensive Care, Kocaeli City Hospital, Kocaeli, Turkey; 10Department of Anesthesiology and Intensive Therapy, Medical University of Lodz, Lodz, Poland; 11Department of Anesthesiology, ICU & Perioperative Medicine Hazm Mebaireek General Hospital HMC, Industrial Area Ar-Rayyan, Doha, QatarCorrespondence: Mustafa Kemal Kucun, Department of Anesthesiology and Intensive Care, Bartın State Hospital, Bartın, Turkey, Email mustafakemalkucun@hotmail.comAim: The aim of this study was to compare the effects of dexmedetomidine, midazolam, propofol, and intralipid on lidocaine-induced cardiotoxicity and neurotoxicity.Methods: Forty-eight male Sprague-Dawley rats were randomly divided into six groups (n = 8 per group): control (C), lidocaine (L), lidocaine + dexmedetomidine (LD), lidocaine + midazolam (LM), lidocaine + propofol (LP), and lidocaine + intralipid (LI). …”
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Prediction of Distant Metastasis of Renal Cell Carcinoma Based on Interpretable Machine Learning: A Multicenter Retrospective Study
Published 2025-01-01“…Jinkai Dong,1,* Minjie Duan,2,3,* Xiaozhu Liu,4,* Huan Li,5 Yang Zhang,6 Tingting Zhang,7 Chengwei Fu,1 Jie Yu,8 Weike Hu,9 Shengxian Peng9,* 1Senior Department of Urology, the Third Medical Center of PLA General Hospital, Beijing, People’s Republic of China; 2Medical School of Chinese PLA, Beijing, People’s Republic of China; 3Medical Innovation Research Department, Chinese PLA General Hospital, Beijing, People’s Republic of China; 4Emergency and Critical Care Medical Center, Beijing Shijitan Hospital, Capital Medical University, Beijing, People’s Republic of China; 5Chongqing College of Electronic Engineering, Chongqing, People’s Republic of China; 6College of Medical Informatics, Chongqing Medical University, Chongqing, People’s Republic of China; 7Department of Endocrinology, Fifth Medical Center of Chinese PLA Hospital, Beijing, People’s Republic of China; 8Department of Medical Imaging, The Affiliated Taian City Central Hospital of Qingdao University, Taian, People’s Republic of China; 9Scientific Research Department, First People’s Hospital of Zigong City, Zigong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shengxian Peng, Scientific Research Department, First People’s Hospital of Zigong City, No. 42, 1st Street, Shangyihao, ZiLiuJing District, ZiGong, SiChuan, 643000, People’s Republic of China, Email 13258280319@163.comBackground: : The traditional tool for predicting distant metastasis in renal cell carcinoma (RCC) is still insufficient. …”
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Harnessing deep learning to detect bronchiolitis obliterans syndrome from chest CT
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Fifteen-second bouts of hyperoxia improve 5-minute time-trial performance in acute hypoxic conditions
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