Identifying Who Benefits the Most from a Community Health Worker-Led Multicomponent Intervention for Hypertension by Meng Pan, Andrea Beratarrechea, Rosana Poggio, Hua He, Chung-Shiuan Chen, Jing Chen, Vilma Irazola, Adolfo Rubinstein, Jiang He, Katherine T. Mills

“…Women (p=0.01), those who were physically inactive (p=0.03), and those not taking antihypertensive medications at baseline (p=0.001) had the greatest BP response. …”
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Nursing of a patient with COPD complicated with type II respiratory failure treated by sequential non-invasive positive pressure ventilation via nasal high-flow oxygen therapy (经鼻高... by QIAO Xinli (乔新立), MA Hailian (马海莲), LI Na (李娜), CHEN Hong (陈宏), TANG Ling (唐玲), ZHANG Ning (张宁), WANG Jingjing (王晶晶), ZHANG Tingting (张婷婷), ZHOU Jie (周洁)

“…Nursing interventions were carried out in the following ways: non-invasive positive pressure ventilation, medication nursing, enteral nutrition support, pipeline maintenance, skin care and psychological nursing and other issues. …”
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Effectiveness of nicotine salt vapes, cytisine, and a combination of these products, for smoking cessation in New Zealand: protocol for a three-arm, pragmatic, community-based rand... by Natalie Walker, Amanda Calder, Joanne Barnes, George Laking, Varsha Parag, Chris Bullen

“…Abstract Background Combining short-acting nicotine replacement therapy with varenicline increases smoking cessation rates compared with varenicline alone, but not all people tolerate these medications or find them helpful. We aim to investigate the therapeutic potential of an analogous combination, by evaluating the effectiveness, safety, and acceptability of combining nicotine salt e-cigarettes with cytisine, compared to nicotine salt e-cigarettes or cytisine only, on smoking abstinence at six months. …”
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HEDDI-Net: heterogeneous network embedding for drug-disease association prediction and drug repurposing, with application to Alzheimer’s disease by Yin-Yuan Su, Hsuan-Cheng Huang, Yu-Ting Lin, Yi-Fang Chuang, Sheh-Yi Sheu, Chen-Ching Lin

“…This capability also supports the design and testing of alternative drugs that are similar to existing medications, enhancing the reliability and interpretability of potential repurposed drugs. …”
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Trends in initial pharmacological COPD treatment in primary care (2010–2021): a population-based study using the PHARMO Data Network by Guilherme Rodrigues, Joana Antão, Qichen Deng, Brenda N. Baak, Alda Marques, Frits M. E. Franssen, Martijn A. Spruit

“…Results A total of 54,628 COPD patients were included (median [IQR] age: 65 [57–73]; 53.7% male), with 36.4% not receiving respiratory medication within 90 days of diagnosis, and 4.2% on other treatments. …”
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Unlocking the Potential of Receptor-Based Approaches in Diabetes Treatment by Mohsina Patwekar, Faheem Patwekar, J. Pavan Kumar, P. Dharani Prasad, Nazia Malik, A. Venkata Badarinath, Prashanth Parupathi, Konatham Teja Kumar Reddy, Selvaraja Elumalai, Zainul Abedeen Ab Samad

“…In the future, these medications are expected to be improved through the use of combination therapy and personalized, precision medicine. …”
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The effectiveness of hyaluronic acid in reducing adverse effects associated with inhaled hypertonic saline therapy in patients with cystic fibrosis: A systematic review and meta-an... by Sana Arshid, Saad Ehsan Ullah, Junaid Imran, Meeran Asher Syed, Aakash Choradia, Nicole Gousy, Sukhman Boparai, Mudassir Shoaib, Bidhan Bikram Shah, Aadarsh Netha

“…This may permit tolerance of the medication in otherwise difficult patients, improve adherence to patients receiving frequent inhalations, and improve therapeutic outcomes…”
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Benzodiazepine agonist treatment for patients with benzodiazepine dependence undergoing opioid agonist treatment: a study protocol for the randomized controlled trial BMX-BAR by Fatemeh Chalabianloo, Lars Thore Fadnes, Jörg Assmus, Jon Mordal, Kristin K. Solli, Kjetil S. Dale, Christina D. Andersen, Silvia Zavenova, Beathe H. Rønning, Andreas W. Blomkvist, Martin Ryssdal, Wasifa S. J. Butt, Anne Marciuch, Anne G. Ørmen, Christian Ohldieck, Else-Marie Løberg, Kjell Arne Johansson, for the BMX-BAR and NORCATS study group

“…Participants will be randomly assigned to receive either a 26-week benzodiazepine stabilizing treatment (15–30 mg diazepam or 50–100 mg oxazepam daily), or a 20-week tapering using the same medications and equivalent initial dosages. All participants will be given access to consultations from OAT therapists with psychosocial follow-up in accordance with current clinical practice. …”
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Short-Term Motor Outcomes in Parkinson’s Disease after Subthalamic Nucleus Deep Brain Stimulation Combined with Post-Operative Rehabilitation: A Pre-Post Comparison Study by Kazunori Sato, Yoshihide Hokari, Eriko Kitahara, Nana Izawa, Kozo Hatori, Kaoru Honaga, Genko Oyama, Taku Hatano, Hirokazu Iwamuro, Atsushi Umemura, Yasushi Shimo, Nobutaka Hattori, Toshiyuki Fujiwara

“…Postoperative rehabilitation combined with STN-DBS may provide short-term improvements in physical function compared with the preoperative medicated status. The improvements in gait step length and trunk function may be important factors for obtaining improvement of postoperative postural stability.…”
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Basolateral amygdala volume in affective disorders using 7T MRI in vivo by Benedikt Kürzinger, Stephanie Schindler, Martin Meffert, Anja Rosenhahn, Robert Trampel, Robert Turner, Peter Schoenknecht, Peter Schoenknecht, Peter Schoenknecht

“…The increase in volume is followed by a reduction phase, as glucocorticoid exposure cumulatively results in excitotoxic damage, reflecting allostatic load.Methods7T magnetic resonance brain imaging was conducted on a total of 84 participants (mean age 38 ± 12 years), comprising 20 unmedicated and 20 medicated individuals with MDD, 21 individuals suffering from bipolar disorder and 23 healthy controls. …”
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Development of Novel Fluticasone/Salmeterol/Tiotropium-Loaded Dry Powder Inhaler and Bioequivalence Assessment to Commercial Products in Rats by Hyukjun Cho, Hyunji Lee, Duhyeong Hwang

“…<b>Background</b>/<b>Objectives</b>: Inhaler devices have been developed for the effective delivery of inhaled medications used in the treatment of pulmonary diseases. …”
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Effectiveness of Oral Semaglutide in Management of Type 2 Diabetes: A Real-World Study from India by Aditya Dutta, Shama Mahendru, Rutuja Sharma, Ambrish Mithal

“…A proforma recorded baseline and follow-up date, medications, body composition, laboratory and clinical parameters. …”
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Integrating general practitioners’ and patients’ perspectives in the development of a digital tool supporting primary care for older patients with multimorbidity: a focus group stu... by Ingmar Schäfer, Vivienne Jahns, Valentina Paucke, Dagmar Lühmann, Martin Scherer, Julia Nothacker

“…The tool also supports a structured medication review. Aims of this study were to consider needs and wants of the target groups in implementing the “multimorbidity” clinical practice guideline in a digital tool, and to examine themes of discussions in order to identify which aspects were considered most important for customising a digital tool.Materials and methodsWe conducted six focus groups with 32 GPs and six focus groups with 33 patients. …”
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New methods of treatment for severe and moderate postoperative pain syndrome in patients with cancer by D.V. Dmytriiev, M.M. Barsa

“…Both groups received medications in accordance with multimodal analgesia protocols (paracetamol 1 g four times daily, dexketoprofen 50 mg three times daily, additional doses of non-steroidal anti-inflammatory drugs (NSAIDs) as needed) and morphine as needed at a maximum dose of 40 mg/day. …”
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Currently prescribed drugs in the UK that could upregulate or downregulate ACE2 in COVID-19 disease: a systematic review by Paul Little, Simon J Griffin, Hajira Dambha-Miller, Nazrul Islam, Ali Albasri, Christopher R Wilcox, Sam Hodgson, Shareen Khan

“…This is leading to trials of repurposed drugs and uncertainty among patients and clinicians concerning continuation or cessation of prescribed medications. Our review indicates that the impact of currently prescribed drugs on ACE2 has been poorly studied in vivo, particularly in human lungs where the SARS-CoV-2 virus appears to enact its pathogenic effects. …”
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Intravitreal Injections for Macular Edema Secondary to Retinal Vein Occlusion: Long-Term Functional and Anatomic Outcomes by Emilia Maggio, Maurizio Mete, Giorgia Maraone, Marcella Attanasio, Massimo Guerriero, Grazia Pertile

“…One eye with CRVO developed endophthalmitis and one with BRVO developed an intraocular pressure increase that was refractory to topical medications and ultimately treated with trabeculectomy. …”
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Effects of a whole body compression garment on recovery after a heavy resistance by Ahmad Arbabı

“…Nutritional intakes, activity, and behavioral patterns (e.g., no pain medications, ice, or long showers over the 24 hours) were replicated 2 days before each test separated by 72 hours. …”
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Access Differentials in Primary Healthcare among Vulnerable Populations in a Health Insurance Setting in Kumasi Metropolis, Ghana: A Cross-Sectional Study by Gertrude Acquah-Hagan, Daniel Boateng, Emmanuel Appiah-Brempong, Peter Twum, Joseph Amankwa Atta, Peter Agyei-Baffour

“…In the crude models, pregnant women had lower prevalence of access to medications as compared to the elderly (prevalence ratio (PR): 0.88; 95% CI: 0.80–0.98). …”
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Unraveling the Beneficial Role of Resveratrol in Fructose-Induced Non-Alcoholic Steatohepatitis with a Focus on the AMPK/Nrf2 Signaling Axis by Soha S. Zakaria, Safaa M. Hanafy

“…These findings underscore the potential of resveratrol as a promising therapeutic agent that can support treatment alongside conventional medications in the management of non-alcoholic steatohepatitis (NASH).…”
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Length of stay in the pediatrics emergency department and associated factors among pediatrics patients in Eastern Ethiopia public hospital, Ethiopia 2022. by Netsanet Melkamu, Amelmasin Faris, Muluken Yigezu, Mickiale Hailu, Anteneh Atle, Manaye Kasahun, Mohammed Kebede, Tsegasew Embiale, Tsinukal Tesfay, Sewmehone Amsalu, Yakob Tadese, Bruck Tesfaye, Gebrehiwot Berie

“…Living in a rural residence ([AOR = 1.65, 95% CI (1.10-2.48)], having a duration of pain > = 12 ([AOR = 1.92, 95% CI (1.13-3.25)], waiting time > = 5 minute ([AOR = 2.24, 95% CI (1.1-4.248541)], having comorbid illness ([AOR = 1.92, 95%CI, 1.13-3.25)], and higher acuity level and absence of medication in the hospital were ([AOR = 2.26, 95%CI (1.02-2.46]) were significantly associated factors for prolonged length of stay.…”
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