Safety assessment of tolvaptan: real-world adverse event analysis using the FAERS database by Peiyang Cao, Qian Wang, Yan Wang, Qing Qiao, Liyuan Yan

“…In the concomitant medication analysis of 7,486 suspected adverse drug reaction reports related to tolvaptan, the top three drugs most commonly used in combination with tolvaptan were furosemide, spironolactone, and amlodipine.ConclusionWhile tolvaptan provides therapeutic benefits, it poses a risk of significant adverse reactions. …”
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Performance evaluation of the smartphone-based AI cough monitoring app - Hyfe Cough Tracker against solicited respiratory sounds [version 2; peer review: 1 approved, 2 approved wit... by Isabel Blavia, Juliane Chaccour, Eric M. Keen, Virginia Orrillo, Mindaugas Galvosas, Matthew Rudd, Juan C. Gabaldón-Figueira, Simon Grandjean Lapierre, Carlos Chaccour, Peter M. Small, Gerard Giménez

“…All continuous audio recordings were independently labeled by three medically-trained researchers. Results: Hyfe Cough Tracker app showed sensitivity of 91% and specificity of 98% with a very high correlation between the cough rate measured by Hyfe and that of human annotators (Pearson correlation of 0.968). …”
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Genetics of Inflammatory Bowel Disease: Current Understanding and Future Directions by P. K. Chandra Sekar, R. Veerabathiran

“…Additionally, the use of certain IBD medications, such as corticosteroids, azathioprine, and infliximab, may have implications for male fertility, necessitating a nuanced understanding of these potential effects for informed decision-making in IBD management. …”
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Quetiapine-related weight loss: Report of a rare adverse effect by Nicodemus Okwudili K Obayi, David HN Nweke, Edidiong Idio, Darlington Okey, Cletus Ozibo

“…Her repeated complaints about the weight gain and threats to stop all medications if nothing was done led to her being switched over to quetiapine. …”
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Diversity and functions of fungal VOCs with special reference to the multiple bioactivities of the mushroom alcohol by Guohua Yin, Geromy G. Moore, Joan Wennstrom Bennett

“…When Drosophila was cultivated in an atmosphere shared with VOC mixtures released from growing cultures of several medically important fungi, including Aspergillus fumigatus, toxicity was observed. …”
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Antioxidant Activity and Reactive Oxygen Species (ROS) Scavenging Mechanism of Eriodictyon californium, an Edible Herb of North America by Allie Richards, Savita Chaurasia

“…Because of rising healthcare costs and mistrust of conventional medicine, mankind is looking for alternatives to over-the-counter medications and prescription drugs, which is driving the demand for nutraceuticals across the globe. …”
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Case Report: Targeted treatment by fluoxetine/norfluoxetine of a KCNC2 variant causing developmental and epileptic encephalopathy by Ping Li, Alice Butler, Yu Zhou, Karl L. Magleby, Christina A. Gurnett, Lawrence Salkoff

“…Here, we describe fluoxetine treatment of two siblings with a de novo KCNC2 V473A variant associated with DEE, which resulted in improved seizure control, ability to wean antiepileptic medications, and improved development. The KCNC2 V437A variant showed GOF activity as demonstrated by HEK293 cells expressing variant subunits activating at more hyperpolarized potentials than WT channels. …”
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Cost-Effectiveness and Budget Impact of Emerging Minimally Invasive Surgical Treatments for Benign Prostatic Hyperplasia by Bilal Chughtai, Sirikan Rojanasarot, Kurt Neeser, Dmitry Gultyaev, Stacey L. Amorosi, Neal D. Shore

“…Procedural, adverse event, retreatment, follow-up, and medication costs were based on 2019 Medicare payment rates and Medicare Part D drug spending. …”
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Effects of intracameral dexamethasone injection versus topical steroids post phacoemulsification operation by Alaa I. A. Ghonim, Mervat E. Elgharieb, Amr A.-F. Gab-Alla, Ehab M. Moawad

“…However, patient compliance and other problems concerning administration with elderly patients self-administering medication drops can vary widely and a wide proportion of them fail to comply with a long-term regimen. …”
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Indigenous and non-Indigenous people experiencing homelessness and mental illness in two Canadian cities: A retrospective analysis and implications for culturally informed action by Brittany Bingham, Akm Moniruzzaman, Michelle Patterson, Jino Distasio, Jitender Sareen, John O’Neil, Julian M Somers

“…We hypothesised that compared with non-Indigenous people, those who are Indigenous would demonstrate histories of displacement earlier in life, higher rates of trauma and self-medication with alcohol and other substances.Design and setting Retrospective data were collected from a sample recruited through referral from diverse social and health agencies in Winnipeg and Vancouver.Participants Eligibility included being 19 years or older, current mental disorder and homelessness.Measures Data were collected via interviews, using questionnaires, on sociodemographics (eg, age, ethnicity, education), mental illness, substance use, physical health, service use and quality of life. …”
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Clinical Utility of an Alzheimer’s Disease Blood Test Among Cognitively Impaired Patients: Results from the Quality Improvement PrecivityAD2 (QUIP II) Clinician Survey Study by Mark Monane, Demetrius M. Maraganore, Robert M. Carlile, Kim G. Johnson, David A. Merrill, Darren R. Gitelman, Kenneth S. Sharlin, Lawren A. VandeVrede, Kristi K. George, Jimin Wang, Tim West, Leslie Jacobs, Philip B. Verghese, Joel B. Braunstein

“…The composite primary endpoint, defined as a change in AD diagnostic certainty, drug therapy, or additional brain amyloid evaluation pre- and post-BBM testing, was 75% (<i>p</i> < 0.0001 versus the pre-specified threshold of 20% clinically meaningful change). Anti-AD medication orders decreased among negative APS2 patients and increased among positive APS2 patients (<i>p</i> < 0.0001). …”
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Effect of an Electronic Pill Bottle on Hydroxychloroquine Adherence in Pediatric Lupus: Results of a Novel Direct‐to‐Family Pilot Trial by Rachel L. Randell, Laura E. Schanberg, Claire Beard, Thomas Phillips, Christoph P. Hornik, Michael Cohen‐Wolkowiez, Stephen J. Balevic, with the CARRA Registry investigators

“…Secondary outcomes included plasma HCQ concentrations and Medication Adherence Self‐Report Inventory (MASRI) scores, collected during four home visits. …”
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Characterization of Clinical Isolates of Enterococci with Special Reference to Glycopeptide Susceptibility at a Tertiary Care Center of Eastern Nepal by Aasish Karna, Ratna Baral, Basudha Khanal

“…Enterococci, once considered as a harmless commensal of intestine, have now emerged as medically important pathogens and are associated with both community-acquired and nosocomial infections. …”
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Patient-reported outcome measures to assess mental and physical health status, functionality, and quality of life in patients with major depression or schizophrenia by Luis San, Belen Arranz, Carlota Romans, Berta García, Marta Coromina, Sonia Ortiz, Miriam Vilaplana, Víctor Soto, Ruth Villaescusa, Joan Alvaros

“…Patients reported that their degree of adherence to treatment was high (77%) and most of them (80%) believed the medication had a beneficial effect. Depressed patients showed both at baseline and at follow up significantly more depressive symptoms than the group with schizophrenia. …”
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Phytomedicine nanoformulations for Parkinson's disease by Chinthu V. Saji, K P Mohanakumar, Rajesh A Shenoi

“…Background: Current medications for Parkinson's disease (PD) primarily offer symptomatic relief, and often lead to adverse effects on long-term use. …”
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Assessing HIV/AIDS patients’ access to antiretroviral drugs using the healthcare accessibility framework: a cross-sectional study from Shandong, China by Zhixin Fan, Songlin Zheng, Weiming Cui, Chao Zheng, Qiang Sun, Jia Yin

“…For the ability to perceive, only 16.6% of respondents self-reported low knowledge of HIV progression and medication. For the ability to seek, 24.3% self-reported having experienced social discrimination, and 21.9% reported 'choosing not to seek health insurance reimbursement due to fear of privacy disclosure. …”
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Cost-savings and health impact of strategies for prevention of Respiratory Syncytial Virus with nirsevimab in Chile based on the integrated analysis of 2019–2023 national databases... by Denis Sauré, Miguel O’Ryan, Juan Pablo Torres, Natalia Trigo, Gonzalo Diaz, Marcel Goic, Charles Thraves, Jorge Pacheco, Patricio Aguilera, Andrea Caro, Leonardo J. Basso

“…We first characterize RSV burden among Chilean infants between 2019 and 2023, focusing on medically attended lower respiratory tract infections (MA LRTI), hospital admissions (HA LRTI), and severe cases requiring ICU admission (ICU LRTI). …”
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Cohort profile: Health in Central Denmark (HICD) cohort - a register-based questionnaire survey on diabetes and related complications in the Central Denmark Region by Annelli Sandbæk, Else-Marie Dalsgaard, Kasper Norman, Lasse Bjerg, Anders Aasted Isaksen

“…In addition to questionnaire data, the cohort is linked to nationwide registries that provide extensive data on hospital diagnoses and procedures, medication use and socioeconomic status decades before enrolment while laboratory registries has provided repeated measures of biochemical markers, for example, lipids, albuminuria and glycated haemoglobin up to 10 years before enrolment.Future plans The HICD will serve as an extensive resource for studies on patient-related information and inequality in type 1 diabetes and type 2 diabetes. …”
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Research progress of combined treatment of western medicine in children with allergic purpura (儿童过敏性紫癜西药联合治疗的研究进展) by HU Yuan (胡园), CHEN Xiuying (陈秀英), LIU Lili (刘莉莉)

“…On the basis of reading a large number of literatures on the combined use of western medicine in the treatment of children with allergic purpura, this paper summarizes, summarizes and summarizes them in order to provide the basis of medication and new research ideas for the combined treatment of children with allergic purpura. …”
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Burden of coeliac disease in Germany: real-world insights from a large retrospective health insurance claims database analysis by Bernd Bokemeyer, Leonarda Serdani-Neuhaus, Juliane Sünwoldt, Christina Dünweber, Svitlana Schnaidt, Detlef Schuppan

“…HCRU (hospitalisations, outpatient visits, medication use, sick leaves) and healthcare costs (outpatient services, inpatient services, outpatient pharmaceuticals, sick leaves and aids and remedies) were compared between CeD patients and controls. …”
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