The Effect of Employees’ Personal Characteristics and Organizational Climate on Organizational Performance, with regard to the Mediating Role of Organizational Knowledge Creation Process (Case Study of Paxan Co (LLP)) by Mohammad Taghi Taghavifard, Jalal Rezaee Noor, Mehdi Seyfollahi, Narges Aghakhani

“…This study has investigated the simultaneous effects of these two variables on organizational performance, as well as the mediating role of the process of organizational knowledge creation and is considered creative with this regard. …”
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Sulfated Cyclocarya paliurus polysaccharides exert immunomodulatory potential on macrophages via Toll-like receptor 4 mediated MAPK/NF-κB signaling pathways by Yue Yu, Haibin Zhu, Mingyue Shen, Qiang Yu, Yi Chen, Shiru Mo, Jianhua Xie

“…Based on Western blot analysis and validation using specific inhibitors against MAPK and NF-κB signaling pathways, the results demonstrated that SCP3 induced macrophages activation and enhanced TNF-α and NO production via TLR4-mediated MAPK and NF-κB pathways. In summary, SCP3 has significant immunomodulatory potential. …”
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Managing malice in negative environments: the mediating effect of coping styles on the relationship between negative sense of place and malevolent creativity among Chinese high school students by Jianzhen Zhang, Jiaxin Lu, Jiahao Ge, Susu Li, Xiaoyu Liang

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Growth mindset of anxiety and avoidant coping as mediators of anxiety across the first year of college: A longitudinal survey of college students in the context of the COVID-19 pandemic by Erin Henshaw, Susan Kennedy, Andrea Lourie, Drexler James, Folly Folivi

“… # Results Path analysis indicate that growth mindset of anxiety and avoidant coping partially mediate the relationship between baseline anxiety and later anxiety outcomes…”
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LncRNA FAM225B Regulates PDIA4-Mediated Ovarian Cancer Cell Invasion and Migration via Modulating Transcription Factor DDX17 by Chanjiao Yao, Lingjuan Zeng, Qin Liu, Xiaoxin Qiu, Chunyan Chen

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Lycium barbarum glycopeptide ameliorates aging phenotypes and enhances cardiac metabolism by activating the PINK1/Parkin-mediated mitophagy pathway in D-galactose-induced mice by Tianchan Peng, Jian Xiang, Yun Tian, Xiaogen Tang, Lina Wang, Lijuan Gao, Oscar Junhong Luo, Li’an Huang, Guobing Chen

“…LbGp attenuated mitochondrial fission and restored impaired PINK1/Parkin-mediated mitophagy pathway caused by D-galactose in cardiomyocytes. …”
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Microwave Ablation Combined with Flt3L Provokes Tumor‐Specific Memory CD8+ T Cells‐Mediated Antitumor Immunity in Response to PD‐1 Blockade by Meixiang Wang, Jing Sang, Fengkuo Xu, Shulong Wang, Peng Liu, Ji Ma, Zhengtao Chen, Qi Xie, Zhigang Wei, Xin Ye

“…The upregulation of ICOSL on migratory cDC1s was pivotal in initiating TTSM‐like cell‐mediated antitumor responses. Slc38a2 may be a critical gene responsible for the upregulation of ICOSL in Mig cDC1s following combined treatment. …”
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Bisphenol A induces apoptosis and disrupts testosterone synthesis in TM3 cells via reactive oxygen species-mediated mitochondrial pathway and autophagic flux inhibition by Wenzhe Yang, Feilong Pan, Tong Zhao, Fangfang Chen, Wenqi Shao, Jinhao Wang, Shirui Wang, Zichen Zhao, Kexiang Liu, Shuchen Zhao, Lijia Zhao

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Development and validation of a nomogram for predicting immune-mediated colitis in lung cancer patients treated with immune checkpoint inhibitors: a retrospective cohort study in China by Qianjie Xu, Xiaosheng Li, Yuliang Yuan, Guangzhong Liang, Zuhai Hu, Wei Zhang, Ying Wang, Haike Lei

“…BackgroundThe increasing utilization of immune checkpoint inhibitors (ICIs) has led to a concomitant rise in the incidence of immune-related adverse events (irAEs), notably immune-mediated colitis (IMC). This study aimed to identify the clinical risk factors associated with IMC development in patients with lung cancer and to develop a risk prediction model to facilitate personalized treatment and care strategies.MethodsThe data collected included 21 variables, including sociodemographic characteristics, cancer-related factors, and routine blood markers. …”
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Effects of Ginkgo biloba Extract on Inflammatory Mediators (SOD, MDA, TNF-α, NF-κBp65, IL-6) in TNBS-Induced Colitis in Rats by Yan-Hong Zhou, Jie-Ping Yu, Yi-Fei Liu, Xiao-Jun Teng, Mei Ming, Peng Lv, Ping An, Shi-Quan Liu, Hong-Gang Yu

“…Mediators of Inflammation…”
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Exploring the mediating role of the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) in the association between obesity and sleep-disordered breathing by Ying Cui, Ziyi Cheng

“…Abstract Purpose Exploring novel mediators affecting the relationship between obesity and sleep-disordered breathing (SDB) is necessary. …”
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The Upregulation of IL-1β Induced by Cisplatin Triggers PI3K/AKT/MMP9 Pathway in Pericytes Mediating the Leakage of the Blood Labyrinth Barrier by Yu M, Jiang WJ, Yu M, Zhou Z, Wang M, Li L

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In Vitro Free Radical Scavenging Properties and Anti-Inflammatory Activity of Ilex paraguariensis (Maté) and the Ability of Its Major Chemical Markers to Inhibit the Production of Proinflammatory Mediators by Ingrid Vicente Farias, Eduarda Fratoni, Lais Cristina Theindl, Angela Machado de Campos, Eduardo Monguilhott Dalmarco, Flavio Henrique Reginatto

“…Mediators of Inflammation…”
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Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Immune-Mediated Necrotizing Myopathy following mRNA SARS-CoV-2 Vaccination by Marta Rodrigues de Carvalho, Myrian Mathildes Sá de Deus Rocha, Vinícius Alves Bezerra, Maciel Eduardo de Pontes, Maria Cristina del Negro, Julio Salgado Antunes, Vinícius Viana Abreu Montanaro, Rubens Nelson Morato Fernandez

“…In this article, we report the case of a young female patient who developed anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMG-CoA) immune-mediated necrotizing myositis (IMNM) after receiving the Pfizer-BioNTech (BNT162b2) COVID-19 vaccine. …”
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Unraveling employee life satisfaction: exploring the impact of psychological contract breach, self-efficacy, mental health, and abusive supervision, with work engagement and job satisfaction as mediators by Md. Abu Issa Gazi, Abdullah Al Masud, Md. Abdul Kaium, Mohammad Bin Amin, Prince Mahmud, Abdul Rahman bin S Senathirajah, Masuk Abdullah

“…Additionally, it examines how work engagement and job satisfaction mediate these effects. Analyzing data from 380 corporate employees in Bangladesh, a survey methodology was employed to test the claimed associations using structural equation modeling (SEM). …”
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Generation of novel oncolytic vaccinia virus with improved intravenous efficacy through protection against complement-mediated lysis and evasion of neutralization by vaccinia virus-specific antibodies by Dong-Sup Lee, Mi-Ju Park, Namhee Lee, Yun-Hui Jeon, Jiyoon Yoo, Suk-kyung Shin, Songyi Lee, Byung-Jin Jung, Yun-Kyoung Hong, Keunhee Oh

“…SJ-607 virus, which showed the highest CD55 expression and the highest resistance to serum complement-mediated lysis, exhibited superior anticancer activity in three human cancer xenograft models, compared with the control Pexa-Vec (JX-594) virus, after single-dose intravenous administration. …”
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Corporate Social Responsibility's Influence on Product Innovation: Spotlight on the Mediating Role of Employer Branding (A Case Study of Medium and Large Manufacturing Firms in Bushehr City) by zahra hajizadeh, Ebrahim Rajabpour, Heidar Ahmadi, Majid Esmaeilpour

“…This study aims to highlight the impact of CSR on product innovation, exploring the mediating role of employer branding within medium and large manufacturing companies of Southern Iran's Bushehr City.   …”
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The protective effects of peptides from Chinese baijiu on AAPH-induced oxidative stress in HepG2 cells via Nrf2-mediated signaling pathway by Jiaying Huo, Yuezhang Ming, Huifeng Li, Anjun Li, Jiwen Zhao, Mingquan Huang, Weizheng Sun, Jihong Wu, Jinglin Zhang

“…Further experiments proved that these peptides exerted antioxidant effects via Nrf2/ARE-mediated signaling pathway by promoting Nrf2 nuclear translocation, inhibiting ubiquitination, and enhancing transcription capacity of Nrf2 in HepG2 cells. …”
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Reducing TRPC1 Expression through Liposome-Mediated siRNA Delivery Markedly Attenuates Hypoxia-Induced Pulmonary Arterial Hypertension in a Murine Model by Cheuk-Kwan Sun, Yen-Yi Zhen, Hung-I Lu, Pei-Hsun Sung, Li-Teh Chang, Tzu-Hsien Tsai, Jiunn-Jye Sheu, Yung-Lung Chen, Sarah Chua, Hsueh-Wen Chang, Yi-Ling Chen, Fan-Yen Lee, Hon-Kan Yip

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Tofogliflozin attenuates renal lipid deposition and inflammation via PPARα upregulation mediated by miR-21a impairment in diet-induced steatohepatitic mice by Sae Nishihara, Masahiro Koseki, Katsunao Tanaka, Takashi Omatsu, Ayami Saga, Hiroshi Sawabe, Hiroyasu Inui, Takeshi Okada, Tohru Ohama, Daisuke Okuzaki, Yoshihiro Kamada, Masafumi Ono, Makoto Nishida, Mikio Watanabe, Yasushi Sakata

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