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IFN Regulatory Factor 1 Mediates Macrophage Pyroptosis Induced by Oxidized Low-Density Lipoprotein in Patients with Acute Coronary Syndrome
Published 2019-01-01“…Mediators of Inflammation…”
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Cannabidiol attenuates lipid metabolism and induces CB1 receptor-mediated ER stress associated apoptosis in ovarian cancer cells
Published 2025-02-01“…In this study, we have demonstrated that CBD significantly inhibits the proliferation of OCs through a cannabinoid receptor type 1 (CB1R)-mediated manner. Fatty acid metabolic profiling and flow cytometry analysis revealed that CBD has the ability to decrease fatty acid levels and significantly suppress the transcription of genes involved in fatty acid uptake and synthesis in ES-2 cells. …”
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The Influence of Financial Literacy, Risk Orientation and Qualified Accountants on Performance in Micro, Small and Medium Enterprises: The Mediating Role of Management Accounting
Published 2024-10-01“…Thus, this study seeks to examine the effect of financial literacy, qualified accounting staff, and risk orientation on performance, with MAPs as a mediating variable within the context of MSMEs from a developing country. …”
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Sorafenib enhanced the function of myeloid-derived suppressor cells in hepatocellular carcinoma by facilitating PPARα-mediated fatty acid oxidation
Published 2025-01-01“…Moreover, our results indicated that sorafenib induced the accumulation of MDSCs mediated by CCR2, and pharmacological blockade of CCR2 markedly reduced MDSCs migration and tumor growth. …”
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Prediction of Emotional Divorce based on Family Communication Patterns with the Mediating Role of Marital Burnout in Married Female Teachers of Darab City
Published 2024-07-01“…Objective: This study aimed to predict emotional divorce among married female teachers in Darab City by analyzing family communication patterns and examining the mediation effect of marital burnout.Methods: Descriptive and correlational analyses were used. …”
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Chain-mediated effect of physical activity between Chinese language-based L2 motivational self-system and intended effort
Published 2025-01-01“…Therefore, the present study examined PA as a mediator and explored its ameliorative effects in L2MSS. …”
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Dual‐Enhanced SERS Satellite Immuno‐Nanocomplex for Multiple PSA‐Mediated PHI Assay Toward Clinical Prostate Cancer Screening
Published 2025-02-01“…Unlike the previous studies focus on the tPSA and fPSA/tPSA ratio (f/t PSA%), this work introduces a multiple PSA‐mediated Prostate Health Index (PHI) assay with significantly increased the predictive accuracy and specificity of PCa, especially the patients with a tPSA level in the “diagnostic gray zone”. …”
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Notch Signaling Mediates TNF-α-Induced IL-6 Production in Cultured Fibroblast-Like Synoviocytes from Rheumatoid Arthritis
Published 2012-01-01“…The aim of this paper was to investigate whether Notch signaling mediated TNF-α-induced cytokine production of cultured fibroblast-like synoviocytes (FLSs) from RA. …”
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Electroacupuncture alleviates paclitaxel-induced peripheral neuropathy by reducing CCL2-mediated macrophage infiltration in sensory ganglia and sciatic nerve
Published 2025-01-01“…Conclusions These findings suggest EA alleviates PIPN by reducing CCL2/CCR2 mediated-pro-inflammatory macrophage infiltration into sensory ganglia as well as the sciatic nerve. …”
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Enhanced silk production and pupal weight in Bombyx mori through CRISPR/Cas9-mediated circadian Clock gene disruption.
Published 2025-01-01“…This study investigates the role of the circadian clock gene Clock in B. mori using CRISPR/Cas9-mediated mutagenesis to establish the ClkΔ29 knock-out mutant strain. …”
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The mediating role of accelerated biological aging in the association between household air pollution from solid cooking fuels and neuropsychiatric disorders
Published 2025-01-01“…Results: Compared to consistent use of cleaner fuels, consistent solid fuel use was associated with a 0.12 (95 % CI: 0.05, 0.18) year increase in KDM-BAA, a 25 % higher risk of neurological disease (HR = 1.25, 95 % CI: 1.03, 1.54), and a 34 % increased risk of psychiatric disorders (HR = 1.34, 95 % CI: 1.02, 1.78). Mediation analysis revealed that KDM-BAA significantly mediated the association between solid cooking fuel and neuropsychiatric diseases, with mediated proportions of 5.96 % (P = 0.006) for neurological disease and 5.71 % (P = 0.024) for psychiatric disease. …”
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The Influence of Brand Image and Electronic Word of Mouth on Purchase Intention of the Originote Products by Tiktok Users with Brand Trust as a Mediator
Published 2025-02-01“… This research explores the effect of brand image and electronic word of mouth (e-WOM) on the purchase intention of Originote products among TikTok users, with brand trust as a mediating factor. Data were collected using an online survey distributed through Google Forms from October 5th, 2024, to December 5th, 2024, yielding 195 valid responses. …”
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