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8621
The contribution of intellectual capital to banks' competitive and financial performance: The evidence from Poland
Published 2022-01-01“…The relation between financial performance and intellectual capital is positively mediated by competitive performance, and environmental factors can affect the strength of this relationship. …”
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8622
Lipoprotein Particle Predictors of Arterial Stiffness after 17 Years of Follow Up: The Malmö Diet and Cancer Study
Published 2020-01-01“…The development of central arterial stiffness previously associated with combined dyslipidemia may be mediated in part by LDL particles, particularly the very small-, small-, and medium-sized LDL particles.…”
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8623
Role and mechanism of dexmedetomidine in regulating bone metabolism in tail-suspended osteoporotic rats
Published 2025-02-01“…Conclusion Dex exerts anti-bone loss effect in tail-suspended rats, which may be associated with its stimulation on osteoblast-mediated bone formation. …”
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8624
Role of B7H4 and Fas in regulation of trophoblast cells and development of pre-eclampsia: a cross-sectional study
Published 2025-12-01“…Overexpression of B7H4 alleviated the inhibitory effects of miR-4319, which were reversed by Fas knockdown (p < 0.05).Conclusions miR-4319 mediates the progression of trophoblast progression by negatively regulating the expression of B7H4 and Fas. …”
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8625
Erbin Regulates Tissue Factors Through Ras/Raf Pathway in Coagulation Disorders in Sepsis
Published 2025-02-01“…In vivo studies have shown that mice with Erbin deletion have more obvious enhanced coagulation function, and in vitro studies have shown that Erbin knockout mediated macrophage secretion of TF by activating the Ras/Raf pathway.Conclusion: Erbin reduces the coagulation activation by inhibiting TF release from macrophages.Keywords: Erbin, coagulation disorders, sepsis, tissue factor, macrophage…”
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8626
The Impact of Family Conflicts on Socio-Economic Prosperity: A Case Study of Muko Sub-County Rubanda District.
Published 2024“…., the results of the study have revealed that some conciliators do not know the law related to inheritance and succession, that is why we recommend them to learn that law and other rules and regulation in force in the country; the findings of the study have proven that some conciliators are biased, so we recommend them to be impartial in order to mediate parts on family based conflicts fairly and the study concluded that it has been revealed by the findings that family based conflicts have a negative impact on economic prosperity of families where dealing with these conflicts bring about spending and consumes time that could be devoted in generating income activities. …”
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8627
Role of Social Factors in Social Economic Status of Families in Kabale Municipality Kabale District.
Published 2025“…., the results of the study have revealed that some conciliators do not know the law related to inheritance and succession, that is why we recommend them to learn that law and other rules and regulation in force in the country; the findings of the study have proven that some conciliators are biased, so we recommend them to be impartial in order to mediate parts on family based conflicts caused by alcohol up take fairly and the study concluded that it has been revealed by the findings that social factors have a negative impact on economic prosperity of families where dealing with these alcoholic beverages bring about spending and consumes time that could be devoted in generating income activities. …”
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8628
IRG1/itaconate enhances efferocytosis by activating Nrf2-TIM4 signaling pathway to alleviate con A induced autoimmune liver injury
Published 2025-02-01“…Exogenous 4-octyl itaconate (OI) supplementation promoted the expression of Nrf2 and TIM4 and restored IRG1-/- bone marrow-derived macrophage (BMDM) efferocytosis, whereas inhibition of Nrf2 mediated by ML385 led to impaired efferocytosis of BMDMs, decreased expression of TIM4, and aggravated liver inflammation injury. …”
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8629
Lipopolymers as the Basis of Non-Viral Delivery of Therapeutic siRNA Nanoparticles in a Leukemia (MOLM-13) Model
Published 2025-01-01“…These results demonstrate the potential of designed lipopolymers in implementing RNAi (via delivery of siRNA) for inhibition of leukemia growth and provide evidence for the feasibility of targeting different oncogenes using siRNA-mediated therapy.…”
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8630
Humoral and cellular immune durability of different COVID-19 vaccine platforms following homologous/heterologous boosters: one-year post vaccination
Published 2025-01-01“…We found that robust T cell mediated immune responses were preserved and largely induced by a heterogeneous vaccination eliciting a significantly higher CD8+ T cells IFN-γ response in 100% of vaccinees regardless of previous natural infection. …”
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8631
Caloric labels do not influence taste pleasantness and neural responses to erythritol and sucrose
Published 2025-03-01“…However, several patterns of brain activity mediated the differences in subjective liking ratings between the sweeteners. …”
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8632
Preconditioning of Rat Bone Marrow-Derived Mesenchymal Stromal Cells with Toll-Like Receptor Agonists
Published 2019-01-01“…Poly(I:C) did not induce statistically significant changes in the release of several inflammatory mediators and VEGF by rBM-MSCs, although it tended to increase IL-6 and MCP-1 secretion, whereas LPS increased the release of IL-6, MCP-1, and VEGF, three factors that were constitutively secreted by unstimulated cells. …”
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8633
Vascular Health in American Football Players: Cardiovascular Risk Increased in Division III Players
Published 2016-01-01“…Vascular health measures included flow-mediated dilation (FMD) and carotid artery intima-media thickness (IMT). …”
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8634
Estrogen-related receptor gamma is a regulator of mitochondrial, autophagy, and immediate-early gene programs in spiny projection neurons: Relevance for transcriptional changes in...
Published 2025-03-01“…Altogether, these studies suggest that ERRγ is a key activator of mitochondrial and lysosomal transcripts in SPNs with a potential bi-functional role as a mediator of immediate-early gene repression. Ongoing studies are investigating mechanisms underlying ERRγ's roles in transcriptional activation and repression in SPNs to inform strategies to promote neuroprotective actions of ERRγ in SPNs in HD.…”
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8635
Recombinant Production of Bovine α<sub>S1</sub>-Casein in Genome-Reduced <i>Bacillus subtilis</i> Strain IIG-Bs-20-5-1
Published 2025-01-01“…Comparative analyses of zeta potential and particle size between pre-cleaned recombinant and native α<sub>S1</sub>-casein showed pH-mediated differences in aggregation behavior. Conclusions: The study demonstrates the potential of <i>B. subtilis</i> for the recombinant production of bovine α<sub>S1</sub>-casein and underlines the potential of genome reduction for the bioproduction of difficult-to-produce proteins.…”
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8636
Spirituality-Based Intervention in Hypertension: EFfects on Blood PrEssure and EndotheliaL Function—FEEL Trial Results
Published 2025-01-01“…Following baseline evaluation, including lifestyle questionnaires, and measurements of office and central blood pressure (BP), home blood pressure monitoring (HBPM) and flow mediated dilation (FMD), patients were randomized to a spirituality-based intervention, which included training for forgiveness, gratitude, optimism, and life purpose delivered by daily WhatsApp communications, or to the control group (CG). …”
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8637
Association of exposure to second-hand smoke during childhood with blood DNA methylation
Published 2025-01-01“…These findings support further research on epigenetic factors mediating deleterious effects of SHS on child health and call for public health policies aimed at reducing exposure, particularly in environments where children are present.…”
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8638
Genomic Characterization of Carbapenemase-Producing Enterobacteriaceae from Clinical and Epidemiological Human Samples
Published 2025-01-01“…Genetic diversity was observed in WGS and phylogenetic analyses, with plasmids often mediating carbapenemase dissemination. <b>Conclusions</b>: The increasing rate of CPE in healthcare settings highlights a critical public health challenge, with limited treatment options. …”
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8639
Differentially expressed microRNAs in pre-transplant lung biopsies target immune checkpoint proteins and can predict primary graft dysfunction in lung transplantation
Published 2025-02-01“…Although PGD is attributed to ischemia-reperfusion injury (IRI), immune responses, primarily T cell-mediated, may play a pivotal role in its pathogenesis. …”
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8640
Gastric Cancer Cell Lines Have Different MYC-Regulated Expression Patterns but Share a Common Core of Altered Genes
Published 2018-01-01“…When we analyzed our DEGs considering KEGG metabolic pathways, we found 12 common branches covering a wide range of biological functions, and three of them were common to all three cell lines: ubiquitin-mediated proteolysis, ribosomes, and system and epithelial cell signaling in Helicobacter pylori infection. …”
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