An Indole Alkaloid Extracted from Evodia rutaecarpa Inhibits Colonic Motility of Rats In Vitro by Guo-xiang Wang, Yan-li Xiang, Hong-gang Wang, Yang-de Miu, Guang Yu

“…This study provides the first evidence that evodiamine can regulate colonic motility in rats by mediating calcium homeostasis in smooth muscle cells. …”
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Immunoinformatic strategy for developing multi-epitope subunit vaccine against Helicobacter pylori. by Md Nahian, Md Rasel Khan, Fabiha Rahman, Hossain Mohammed Reza, Imren Bayil, Tanjum Ahmed Nodee, Tabassum Basher, Mostafizur Rahaman Sany, Rabeya Najnin Munmun, S M Ariful Habib, Lincon Mazumder, Mrityunjoy Acharjee

“…Additionally, immune simulations showed elevated levels of cell-mediated immunity, while repeated exposure simulations indicated rapid antigen clearance. …”
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The age and residence impact on IgE serum level in patients with allergic asthma by Raghdah Maytham Hameed, Huda Hadi Al-Hasnawy, Haidar Abdul Amir Najim Abood

“…Abstract Background: Immunoglobulin E (IgE) has a role in mediating allergic reactions and their powerful effector functions, but numerous factors influence its value. …”
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Axial Spondyloarthritis in Black Americans: An Observational Study From Five Centers in Shelby County, Tennessee by Krishna Kommineni, Iman Abutineh, Cathy Chapman, Debendra Pattanaik, Mohamad Bittar

“…Objective Axial spondyloarthritis (axSpA) is an immune‐mediated disease that predominantly affects the axial skeleton. …”
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Magnitude of Psoriasis and Its Associated Factors, and Quality of Life of Psoriasis Patients among Patients Who Attend Dermatology Clinic at Tibebe Ghion Comprehensive Specialized... by Wosen Ketema, Solomon Ketema Bogale, Eyob Ketema Bogale

“…Psoriasis is a common immune-mediated papulosquamous inflammatory skin disease characterized by well-demarcated, erythematous silvery scaly plaques. …”
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HIF-3α-Induced miR-630 Expression Promotes Cancer Hallmarks in Cervical Cancer Cells by Forming a Positive Feedback Loop by Qiaohui Gao, Zhenghua Ren, Shengyuan Jiao, Juan Guo, Xia Miao, Jin Wang, Junye Liu

“…Consequently, stable overexpression of miR-630 in HeLa cells promotes cancer hallmarks, including radioresistance, inhibition of apoptosis, increased migration and invasion, and EMT-mediated metastasis. Meanwhile, inhibition of miR-630 showed opposite features. …”
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Time Course of Brain Activity Changes Related to Number (Quantity) Processing Triggered by Digits Versus Number Words: An Event-Related Potential (ERP) Study by Peter Walla, Philipp Klimovic

“…Furthermore, it can be concluded that digits are better symbols for mediating quantity processing in the human brain than number words.…”
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CSE-8, a filamentous fungus-specific Shr3-like chaperone, facilitates endoplasmic reticulum exit of chitin synthase CHS-3 (class I) in Neurospora crassa by Samantha Verónica González-Téllez, Meritxell Riquelme

“…The current evidence suggests that the biogenesis of CHS exclusive to filamentous fungi may involve pathways independent of CSE-mediated receptors.…”
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Rabies epidemiology, prevention and control in Nigeria: Scoping progress towards elimination. by Philip P Mshelbwala, J Scott Weese, Olufunmilayo A Sanni-Adeniyi, Shovon Chakma, Stephen S Okeme, Abdullah A Mamun, Charles E Rupprecht, R J Soares Magalhaes

“…<h4>Conclusion</h4>Significant improvements are necessary to achieve the elimination of human rabies mediated via dogs by 2030.…”
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Gene Expression of CD70 and CD27 Is Increased in Alopecia Areata Lesions and Associated with Disease Severity and Activity by Radwa El- Sayed Mahmoud Marie, Noha M. Abd El-Fadeel, Yara El-Sayed Marei, Lina M. Atef

“…Alopecia areata (AA) is an acquired hair loss disorder induced by a cell-mediated autoimmune attack against anagen hair follicles. …”
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Emodin promotes the recovery of rheumatoid arthritis by regulating the crosstalk between macrophage subsets and synovial fibroblast subsets by Lianying Cheng, Xiaofeng Rong

“…Moreover, MerTKposTREM2high STM‐mediated secretion of exosomes was promoted, which can inhibit the secretion of pro‐inflammatory factors by FAPα+THY1+ FLSs and promote the secretion of anti‐inflammatory factors by FAPα+THY1+ FLSs, thereby inhibiting FAPα+THY1−FLS proliferation and migration, improving the local immune microenvironment, and inhibiting RA damage. …”
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Relationship of Serum IL-12 to Inflammation, Hematoma Volume, and Prognosis in Patients With Intracerebral Hemorrhage by Yazhao Zhang, Yanan Tian, Jianhui Wei, Yi Xiang

“…Interleukin-12 (IL-12) promotes brain inflammation, and regulates coagulation mediated by red blood cells and platelets. This study was designed to investigate the relationship of serum IL-12 to inflammation, hematoma volume, and prognosis in ICH patients. …”
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A Study of Occupational Therapy Strategies and Psychological Regulation of Students’ Internet Addiction in the Mobile Social Media Environment by Xueqin Zhang

“…Student peer attachment significantly and positively predicted adolescent Internet addiction; Internet use peer pressure played an incomplete mediating role in the prediction of peer attachment to Internet addiction; loneliness played a moderating role in the pathway of peer attachment to Internet addiction, and loneliness also played a moderating role in the pathway of peer attachment to Internet use peer pressure. …”
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Adipokines in Breast Cancer: Decoding Genetic and Proteomic Mechanisms Underlying Migration, Invasion, and Proliferation by Ließem A, Leimer U, Germann GK, Köllensperger E

“…Migration and invasion behaviors were quantified using specialized Boyden chamber assays.Results: We found significant, adipokine-mediated genetic and proteomic alterations, with PCR showing an up to 6-fold increase of numerous malignancy-associated genes after adipokine-supplementation. …”
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THE ROLE OF US IN CHINA – TAIWAN CRISIS by EDGAR AGUBAMAH

“…Be that as it may this work recommended that the US should abandon her partial strategic ambiguity (that is they will not commit to go to war to defend Taiwan, nor will they take the war option off the table if Taiwan is attacked) and other subtle supports to Taiwan and play a clear and transparent mutual meditative role in China-Taiwan crisis so that the issue between China and Taiwan can be settled amicably. A truthful mediator must prove herself or himself impartial. …”
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Severe Plasmodium falciparum malaria is associated with circulating ultra-large von Willebrand multimers and ADAMTS13 inhibition. by Deirdre Larkin, Bas de Laat, P Vince Jenkins, James Bunn, Alister G Craig, Virginie Terraube, Roger J S Preston, Cynthia Donkor, George E Grau, Jan A van Mourik, James S O'Donnell

“…These novel findings suggest that severe P. falciparum infection is associated with acute endothelial cell activation, abnormal circulating ULVWF multimers, and a significant reduction in plasma ADAMTS13 function which is mediated at least in part by an unidentified inhibitor.…”
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Towards the Universal Health Coverage in Ghana: An exploratory, cross-sectional study on the National Health Insurance Scheme by Richard Boateng, Alfred E Yawson

“…Discussion and Conclusion: Findings of our study showed that perceived quality of healthcare services delivered by NHIS may play a certain role on the attainment of UHC both directly and by mediating effects of UHA and FRP. Therefore, good healthcare services provided by NHIS can promote universal healthcare access and financial risk protection as major catalysts towards the attainment of UHC in Ghana.…”
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From green demand to deceptive practices: A cross-cultural study the impact of consumer green preferences on corporate greenwashing behavior in China, Republic of Korea, and Malays... by Zhibin Tao

“…Utilizing valid survey data from 1433 enterprises across these three countries, and employing SEM and fsQCA methods, the empirical test results indicate that among the three countries: (1) Consumer green preferences lead to corporate engagement in greenwashing behavior. (2) Consumer green preferences lead to market competitive pressure. (3) Market competitive pressure results in corporate greenwashing behavior. (4) Market competitive pressure plays a significant mediating role in the process by which consumer green preferences influence corporate greenwashing behavior. (5) Regulatory environment plays a moderating role in some of the impact paths across different countries, and in some impact paths, the moderating effect is absent. (6) The analysis results using the fsQCA method show that there are 4 different configurations leading to strong greenwashing behavior in enterprises in China, 3 in Republic of Korea, and 4 in Malaysia, and the most influential and explanatory configurations and paths have been identified. …”
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The PTP1B Inhibitor Trodusquemine (MSI-1436) Improves Glucose Uptake in Equine Metabolic Syndrome Affected Liver through Anti-Inflammatory and Antifibrotic Activity by Lynda Bourebaba, Anna Serwotka-Suszczak, Nabila Bourebaba, Magdalena Zyzak, Krzysztof Marycz

“…Interestingly, PTP1B inhibition ameliorated the expression of TIMP-1 and Smad7, both important antifibrotic mediators. Furthermore, application of MSI-1436 was found to augment the abundance of glycosylated Glut-2, which subsequently expanded the glucose absorption in the EMS liver, probably due to an enhanced Glut-2 stability and half-life onto the plasma cell membranes. …”
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The influences of environmental awareness on green performance by M.H. Mansour

“…To evaluate the model, Smart Partial Least Square was employed to conduct validity and reliability testing and develop structural equation modeling.FINDINGS: According to the results, Environmental awareness mediated the effects of green human resource management and green behaviours on green performance. …”
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