Nitroxyl protects H9C2 cells from H/R-induced damage and inhibits autophagy via PI3K/Akt/mTOR pathway. by Li Li, Zhixin Wang, Yaxuan Lyu, Yanqing Guo

“…Further experiments demonstrated that the effects of HNO were mediated through upregulation of PI3K/Akt/mTOR pathway. …”
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THE SOCIAL THEORY OF MAX WEBER IN CONFLICT OF INTERPRETATIONS by Zenonas Norkus

“…Tenbruck) while W. Schluchter tried to mediate in this conflict seeing Weber’s work as led by "minimalist" evolutionist research program. …”
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Multi-modal investigation reveals pathogenic features of diverse DDX3X missense mutations. by Federica Mosti, Mariah L Hoye, Carla F Escobar-Tomlienovich, Debra L Silver

“…These findings highlight aberrant RNA metabolism and DNA damage in DDX3X-mediated neuronal cell death. In sum our findings reveal new mechanisms by which clinically distinct DDX3X missense mutations differentially impair neurodevelopment.…”
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Levels of subject communication in fiction literature by A. S. Komarov

“…The intercourse between the self of the writer and the self of the reader realizes itself in the processes of writing and reading belles-lettres texts that serve as specific mediators between the two selfs. The article shows the free and personal nature of the intercourse. …”
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Effects of e-cigarette smoking on periodontal health: A scoping review. by Priti Charde, Kamran Ali, Nader Hamdan

“…<h4>Results</h4>A total of 23 clinical studies focusing on the effect of e-cigarette smoking on the periodontal clinical parameters, levels of inflammatory mediators, alteration in periodontal microflora, and response to periodontal treatment were found to be eligible for inclusion in the review. …”
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Nitric Oxide - Its Importance in Swallowing, Inflammatory Bowel Disease and Cirrhotic Cardiomyopathy by ABR Thomson

“…The neurosubstances mediating striated and smooth muscle peristalsis may be both anatomically and neurochemically distinct. …”
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Peran Organisasi Berbasis Masyarakat dalam Inovasi Keberlanjutan Komunitas UMKM Menuju Kota Cerdas by Winny Astuti, Chrisna Tri Hadi Permana, Hakimatul Mukaromah

“…Hasil penelitian menunjukkan bahwa peran OBM dominan dalam menginisiasi inovasi dan teknologi sekaligus sebagai wadah pertukaran pengetahuan, mediator transfer teknologi dan inovasi ramah lingkungan. …”
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RELIGIOUS COMMUNICATION IN THE CONTEXT OF CULTURE MEDIA by Maria S. Petrushkevych

“…Phenomena, that reflects the dramatic changes in the communicative environment are: mediatization of body and mind, the new practice of processing / reading information, the phenomenon of simultaneous perception of a large number of information channels – similar or different. …”
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The risk of believing that emotions are bad and uncontrollable: association with orthorexia nervosa by L. Vuillier, M. Greville-Harris, R. L. Moseley

“…Suppression, but not reappraisal, partially mediated the relationship between beliefs about emotions and ON symptoms. …”
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Prevalence of Esophageal Eosinophilia, Eosinophilic Esophagitis, and Lymphocytic Gastritis in Children with Celiac Disease: A Saudi Tertiary Center Experience by Meshari A. Alaifan, Ammar Khayat, Rana Y. Bokhary, Abdulhameed Ibrahim, Yagoub Bin-Taleb, Bakr H. Alhussaini, Omar I. Saadah

“…Celiac disease (CD) is an immune-mediated enteropathy that has been associated with other immune-related gastrointestinal disorders, such as eosinophilic esophagitis (EoE) and lymphocytic gastritis (LG). …”
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Historical traditions of democracy in Ukraine by Stechyshyn A.

“…The main regulatory act regulating the procedure of direct people’s power is the Constitution of Ukraine, which regulates the main forms of expression of the will of the people and spheres of influence. With regard to mediated people’s power or representative democracy, it also has a long history and practice in the Ukrainian legal tradition, which is implemented primarily in the process of formation of local self-government bodies. …”
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A Foxf1-Wnt-Nr2f1 cascade promotes atrial cardiomyocyte differentiation in zebrafish. by Ugo Coppola, Bitan Saha, Jennifer Kenney, Joshua S Waxman

“…Functionally, we find that Wnt signaling acts downstream of Foxf1 to promote expression of the 3'reg1 reporter within ACs and, importantly, both Foxf1 and Wnt signaling require Nr2f1a to promote a surplus of differentiated ACs. CRISPR-mediated deletion of the endogenous 3'reg1 abrogates the ability of Foxf1 and Wnt signaling to produce surplus ACs in zebrafish embryos. …”
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Viral and Nonviral Engineering of Natural Killer Cells as Emerging Adoptive Cancer Immunotherapies by Sandro Matosevic

“…Alongside expressing chimeric antigen receptors to overcome immune escape by cancer cells, enhance their recognition, and mediate their killing, NK cells have been genetically modified to enhance their persistence in vivo by the expression of cytokines such as IL-15, avoid functional and metabolic tumor microenvironment suppression, or improve their homing ability, enabling enhanced targeting of solid tumors. …”
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Burden of coeliac disease in Germany: real-world insights from a large retrospective health insurance claims database analysis by Bernd Bokemeyer, Leonarda Serdani-Neuhaus, Juliane Sünwoldt, Christina Dünweber, Svitlana Schnaidt, Detlef Schuppan

“…Background: Coeliac disease (CeD) is a chronic immune-mediated disease triggered by exposure to dietary gluten in genetically predisposed individuals. …”
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“Tramando arames, pedras e fios”: espaço e estigma no trabalho de um artista by Carolina Dalla Chiesa, Pedro Henrique de Gois, Gabriela De Luca, Neusa Rolita Cavedon

“…This article aims at evidencing the stigmas related to the work developed by a street artist, specifically, in the centre of the city of Porto Alegre, a crowded spot typical of large cities where the degradation and revitalization of the space turn fears and sociability into mediators for the interactions that happen there. In order to reach this objective, we base the study mainly on the notion of stigma and the transformations that happen over time in the artisan’s and artist’s work, and look at space from an anthropological perspective, bearing in mind the meanings attributed to it. …”
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Flavonoids as Strong Inhibitors of MAPK3: A Computational Drug Discovery Approach by Amir Taherkhani, Parita Khodadadi, Lida Samie, Zahra Azadian, Zeynab Bayat

“…Mitogen-activated protein kinase 3 (MAPK3) mediates the onset, progression, metastasis, drug resistance, and poor prognosis in various malignancies, including glioma, liver, ovarian, thyroid, lung, breast, gastric, and oral cancers. …”
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Exploring the anticancer potential of Hewittia malabarica through phytochemical analysis and molecular docking study by Shiji Thozhukkad Moosaripparambil, Kannan Vadakkadath Meethal

“…These results indicate that the mechanism of cytotoxicity observed may be mediated through induction of apoptosis in cancer cell lines. …”
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A peripheral subepithelial network for chemotactile processing in the predatory sea slug Pleurobranchaea californica. by Tigran Norekian, Yichen Liu, Ekaterina D Gribkova, Jilai Cui, Rhanor Gillette

“…Ciliary clusters likely drive the sensory nerve spikes via SeN, mediating appetitive and stimulus place codes to CNS. …”
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Endotoxin Triggers Tumor Initiation Events in Nontumorigenic Breast Epithelial Cells and Enhances Invasion-Related Phenotype in Pretumorigenic and Tumorigenic Breast Epithelial Cel... by Farah Yassine, Sabreen F. Fostok, Nataly Naser Al Deen, Rabih S. Talhouk

“…Results showed that short-term ET exposure upregulated matrix metalloproteinase-9 (MMP-9) activity in nontumorigenic mammary epithelial cells of mouse (SCp2) and human origins (HMT-3522 S1; S1) and upregulated inflammatory mediators including nitric oxide (NO) and interleukin 1-β in tumorigenic human breast cells (MDA-MB-231), all in a dose-dependent manner. …”
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A versatile site-directed gene trap strategy to manipulate gene activity and control gene expression in Caenorhabditis elegans. by Haania Khan, Xinyu Huang, Vishnu Raj, Han Wang

“…We show that, by recombinase-mediated cassette exchange (RMCE) via microinjection or genetic crossing, the cGAL gene trap lines can be further engineered in vivo to easily swap cGAL with other bipartite expression systems' drivers, including QF/QF2, Tet-On/Tet-Off, and LexA, to generate new gene trap lines with different drivers at the same genomic locus. …”
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