Mesenchymal Stromal Cells Mediate Clinically Unpromising but Favourable Immune Responses in Kidney Transplant Patients by Urvashi Kaundal, Raja Ramachandran, Amit Arora, Deepesh B. Kenwar, Ratti Ram Sharma, Ritambhra Nada, Mukut Minz, Vivekanand Jha, Aruna Rakha

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HPLC-MS/MS-Mediated Analysis of the Pharmacokinetics, Bioavailability, and Tissue Distribution of Schisandrol B in Rats by Dahu Liang, Zijing Wu, Yanhao Liu, Chao Li, Xianghong Li, Bin Yang, Haitang Xie, Hua Sun

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From Uncertainty to Anxiety: How Uncertainty Fuels Anxiety in a Process Mediated by Intolerance of Uncertainty by Yuanyuan Gu, Simeng Gu, Yi Lei, Hong Li

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Nomophobia and University Business Students’ Burnout in Online Learning: Mediating effect of Fear of Missing Out by Gangaram Biswakarma, Basu Dev Lamichhane, Deepika Neupane, Keshav Subedi

“…The study found a significant relationship between Nomophobia, FoMO, and SBO, where Nomophobia affects FoMO and SBO, while FoMO notably impacts SBO's academic efficacy. FoMO partially mediates the Nomophobia-SBO relationship. Gender doesn't moderate the relationship with SBO, indicating no distinction between male and female students. …”
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Presynaptic CRF1 Receptors Mediate the Ethanol Enhancement of GABAergic Transmission in the Mouse Central Amygdala by Zhiguo Nie, Eric P. Zorrilla, Samuel G. Madamba, Kenner C. Rice, Marissa Roberto, George Robert Siggins

“…These data indicate that presynaptic CRF1 receptors play a critical role in permitting or mediating ethanol enhancement of GABAergic synaptic transmission in CeA, via increased vesicular GABA release, and thus may be a rational target for the treatment of alcohol abuse and alcoholism.…”
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CRISPR/Cas9-mediated genomic insertion of functional genes into Lactiplantibacillus plantarum WCFS1 by Kamilla Wiull, Lisa K. Haugen, Vincent G. H. Eijsink, Geir Mathiesen

“…Our system successfully knock-in four expression cassettes varying in length from ~800–1,300 bp with high efficiency and insert an expression cassette encoding a SARS-CoV-2 antigen receptor-binding domain (RBD) with an anchor mediating surface display, which has not been achieved previously using CRISPR/Cas9. …”
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Fun at work and knowledge sharing: The mediating role of organizational inclusion and moderating role of authentic leadership by Ishfaq Ahmed

“…Building upon organizational support theory, this study proposes and empirically investigates this relationship through the mediation of organizational inclusion and moderation of authentic leadership. …”
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Neuropilin1-dependent paracrine signaling of cancer cells mediated by miRNA exosomal cargo by Claudia Palazzo, Roberta Mastrantonio, Noemi Gioelli, Erika Testa, Francesco Recco, Donatella Lucchetti, Giulia Villari, Alessio D’Alessio, Alessandro Sgambato, Flavio Mignone, Guido Serini, Maria Teresa Viscomi, Luca Tamagnone

“…Results In this study, we show that diverse human cancer cells release NRP1 embedded in exosome-like small extracellular vesicles, which mediate a previously unknown NRP1-dependent paracrine signaling mechanism regulating endothelial cell migration. …”
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The Helplessness Dimension of Pain Catastrophizing Mediates the Relation between PTSD Symptoms and Pain Rehabilitation Measures by Matthew Schumann, Julia Craner, Elizabeth Kacel, Eleshia Morrison, Keith Gascho, Judy Gebhard, Wesley Gilliam

“…The patients completed measures of pain severity, pain interference, pain catastrophizing, depressive symptoms, quality of life (QOL), and PTSD symptoms at pretreatment. Results. Parallel mediation analyses were conducted to evaluate the mediating effect of the Pain Catastrophizing Scale subscales on the relationship between PTSD symptomatology and pain-relevant variables. …”
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Internet Gaming Disorder and Unmet Psychological Needs: Mediating Roles of Self-Esteem, Depression, and Escapism by Z. Gedik, M. Gulec

“…It was found that self-esteem, depression, and escapism serially mediated the association between basic psychological needs and IGD. …”
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Multi-Modal Social Robot Behavioural Alignment and Learning Outcomes in Mediated Child–Robot Interactions by Paul Baxter

“…A large touchscreen is employed as a mediating device between a child and a robot. Collaborative sCRI is emphasised, with the touchscreen providing a common set of interaction affordances for both child and robot. …”
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The Mediating Role of Human Resources and Internal Processes on the Relationship between Innovation Strategy and Financial Performance by Vajiheh Dehghan, Mahmoud Moeinadin, Soheila Shahrestani

“…Therefore, the present study investigates the role of innovation strategy in the financial performance of active manufacturing companies in Yazd province through human resource mediator variables and internal processes. Methodology: The present research is a descriptive survey. …”
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Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD by Shaowei Wang, Boyang Li, Jie Li, Zhiheng Cai, Cristelle Hugo, Yi Sun, Lu Qian, Julia TCW, Helena C. Chui, Dante Dikeman, Isaac Asante, Stan G. Louie, David A. Bennett, Zoe Arvanitakis, Alan T. Remaley, Bilal E. Kerman, Hussein N. Yassine

“…Unbiased proteomic screening was performed to identify the proteins that mediate cellular ABCA1 trafficking. We created ABCA1 knock out cell lines and mouse models to validate the role of ABCA1 in cholesterol-induced mTORC1 activation and senescence. …”
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Immune-mediated mechanisms in acute osteofascial compartment syndrome: insights from multi-omics analysis by Qinzhen Lu, He Ling, Yonghui Lao, Junjie Liu, Wei Su, Zhao Huang

“…Results Our research findings indicate that AOCS is an immune-mediated inflammatory disease, primarily involving immune cells, especially neutrophils. …”
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Vimentin-Rab7a Pathway Mediates the Migration of MSCs and Lead to Therapeutic Effects on ARDS by Kai Wang, Boxiang Du, Yan Zhang, Congyou Wu, Xiuli Wang, Xu Zhang, Liwei Wang

“…In conclusion, we have shown that the Vimentin-Rab7a pathway mediates migration of MSCs and leads to therapeutic effects in ARDS.…”
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Gnidia glauca- and Plumbago zeylanica-Mediated Synthesis of Novel Copper Nanoparticles as Promising Antidiabetic Agents by Dhiraj A. Jamdade, Dishantsingh Rajpali, Komal A. Joshi, Rohini Kitture, Anuja S. Kulkarni, Vaishali S. Shinde, Jayesh Bellare, Kaushik R. Babiya, Sougata Ghosh

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Lipid nephrotoxicity mediated by HIF-1α activation accelerates tubular injury in diabetic nephropathy by Zebo Hu, Qianwen Zhu, Ying Wang, Xue Deng, Hui Yang, Mingjun Zhou, Jiyuan Zhang, Hao Wang, Haosen Wang, Lin Wang, Cui Zhang, Shu Li

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Upper Ocean Thermal Responses to Sea Spray Mediated Turbulent Fluxes during Typhoon Passage by Lianxin Zhang, Changlong Guan, Chunjian Sun, Siyu Gao, Shaomei Yu

“…A one-dimensional turbulent model is used to investigate the effect of sea spray mediated turbulent fluxes on upper ocean temperature during the passage of typhoon Yagi over the Kuroshio Extension area in 2006. …”
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Reflective functioning mediates the relationship between insecure adult attachment and the severity of prolonged grief symptoms by Serena Giunta, Giuseppe Mannino, Lucia Sideli, Maria C. Quattropani, Vittorio Lenzo

“… # Results Certainty about mental states fully mediated the relationship between both the attachment avoidance and attachement anxiety and severity of prolonged grief symptoms…”
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Pivotal Cytoprotective Mediators and Promising Therapeutic Strategies for Endothelial Progenitor Cell-Based Cardiovascular Regeneration by Hyunyun Kim, Sujin Kim, Sang Hong Baek, Sang-Mo Kwon

“…Therefore, an understanding of diverse EPC-related cytoprotective mediators underlying EPC homeostasis in ischemic tissues may help to overcome current obstacles for EPC-mediated cell therapy for CVDs. …”
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