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  1. 7881

    Indigenous Environmental Activism and Media Depiction by Raphaela G O Pavlakos

    Published 2025-01-01
    “…I argue that anything human-mediated holds bias, including photographs. Because of this, I propose reading the performance of Indigenous-led environmental activism through media representation, specifically photographs used in media coverage of Indigenous environmental activism. …”
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  2. 7882

    VCP downstream metabolite glycerol-3-phosphate (G3P) inhibits CD8+T cells function in the HCC microenvironment by Cheng Cheng, Qingrui Zha, Linmao Sun, Tianming Cui, Xinyu Guo, Changjian Xing, Zhengxiang Chen, Changyong Ji, Shuhang Liang, Shengwei Tao, Junhui Chu, Chenghui Wu, Qi Chu, Xuetian Gu, Ning Zhang, Yumin Fu, Shumin Deng, Yitong Zhu, Jiabei Wang, Yao Liu, Lianxin Liu

    Published 2025-01-01
    “…These findings highlight a previously unrecognized mechanism involving VCP and G3P in suppressing T-cell-mediated immunity in the TME, positioning VCP as a promising upstream target for enhancing immunotherapy in HCC.…”
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  3. 7883

    Autophagy activation alleviates annulus fibrosus degeneration via the miR-2355-5p/mTOR pathway by Zilin Yu, Chunyang Fan, Yubo Mao, Xiexing Wu, Haiqing Mao

    Published 2025-01-01
    “…Conclusions Autophagy, mediated by the miR-2355-5p/mTOR pathway, plays a protective role in AFCs degeneration. …”
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  4. 7884

    Novel architecture of ternary ZnO/PMA/AgI heterojunctions towards boosted visible-light photocatalytic destruction of antibiotics by Yossor R. Abdulmajeed, Saad H. Ammar, Nada D. Ali, Fatma D. Ali, A. Al-Farraji, Marwa A. Lafta

    Published 2025-01-01
    “…This achievement was attributed to the high redox properties of PMA as an effective electron transfer mediator between AgI and ZnO semiconductors. Moreover, the developed heterojunction facilitates the migration and separation of photoproduced charge carriers. …”
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  5. 7885

    Defensive healthcare practice: systematic review of qualitative evidence by James Thomas, Melissa Harden, Theo Lorenc, Claire Khouja, Helen Fulbright

    Published 2024-07-01
    “…The qualitative evidence calls into question the view of defensive practice as a key mediator linking litigation risk to inappropriate treatment and excess costs.…”
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  6. 7886

    EMC2 suppresses ferroptosis via regulating TFRC in nasopharyngeal carcinoma by Xianghui Chen, Xiaoyan Wang, Yuxia Zou, Yan Wang, Tingting Duan, Zijie Zhou, Yi Huang, Qing Ye

    Published 2025-02-01
    “…EMC2 regulated ferroptosis by mediating the level of TFRC. Conclusions: EMC2 suppresses ferroptosis and promotes tumor progression, and the EMC2-TFRC axis is a novel ferroptosis regulatory pathway. …”
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  7. 7887

    Seaweed (Porphyra) cultivation enhances production of autochthonous refractory dissolved organic matter in coastal ecosystems by Ting Wang, Ting Wang, Jiajun Xu, Jiajun Xu, Randy A. Dahlgren, Qiang Liu, Yang Jia, Yang Jia, Binbin Chen, Binbin Chen, Hanqin Xu, Hanqin Xu, Zengling Ma, Zengling Ma, Liyin Qu, Liyin Qu

    Published 2025-02-01
    “…Redundancy analysis revealed that more microbial modules mediated organic matter transformations during the cultivation period, leading to a 169% higher estuarine addition of microbially-sourced humic-like C3 compared to the non-cultivation period. …”
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  8. 7888
  9. 7889

    The Synergistic Effect of TRPV1 on Oxidative Stress-Induced Autophagy and Apoptosis in Microglia by Tingting Huang, Yao Lin, Qiongyi Pang, Weimin Shen, Xiang Chen, Fengxia Tu

    Published 2021-01-01
    “…However, the experimental results do not fully demonstrate that the TRPV1-mediated antioxidative and antiapoptosis effect is through the affecting autophagy entirely.…”
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  10. 7890

    Pharmacological and structural insights into nanvuranlat, a selective LAT1 (SLC7A5) inhibitor, and its N-acetyl metabolite with implications for cancer therapy by Chunhuan Jin, Xinyu Zhou, Minhui Xu, Hiroki Okanishi, Ryuichi Ohgaki, Yoshikatsu Kanai

    Published 2025-01-01
    “…Abstract L-type amino acid transporter 1 (LAT1, SLC7A5), overexpressed in various cancers, mediates the uptake of essential amino acids crucial for tumor growth. …”
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  11. 7891

    Isoforsythiaside confers neuroprotection against Alzheimer’s disease by attenuating ferroptosis and neuroinflammation in vivo and in vitro by Chunyue Wang, Hongbo Jiang, Honghan Liu, Shanshan Chen, Hangyu Guo, Shuoshuo Ma, Weiwei Han, Yu Li, Di Wang

    Published 2023-09-01
    “…The purpose of this study was to explore the anti-ferroptosis and anti-neuroinflammatory properties of IFY-mediated neuroprotection. In APP/PS1 mice, erastin-damaged HT22 cells, and LPS-exposed BV2 cells, the neuroprotective effects against ferroptosis and neuroinflammation were investigated using immunohistochemistry, label-free proteomics, western blot, ELISA, MTT, fluorescence, and TEM. …”
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  12. 7892
  13. 7893

    After Treatment Decrease of Bone Marrow Tregs and Outcome in Younger Patients with Newly Diagnosed Acute Myeloid Leukemia by Mario Delia, Paola Carluccio, Anna Mestice, Roberta Frappampina, Francesco Albano, Giorgina Specchia, Pellegrino Musto

    Published 2020-01-01
    “…However, the role of BMA Tregs in mediating immune system-AML interactions in the diagnostic and posttreatment phase should be confirmed in a greater number of patients.…”
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  14. 7894

    Mixed Cutaneous Infection Caused by Leishmania and Dermatophytes: A Rare Coincidence or Immunological Fact by Amresh Kumar Singh, Ankur Kumar, Jayesh Pandey, Vivek Gaur, Pratima Tripathi, Indra Prasad Adhikari

    Published 2021-01-01
    “…Tinea is a fungal infection of the skin, which can become more extensively pathogenic particularly in patients with depressed cell-mediated immunity. Regulatory T cells and Th17 cells have been shown to be responsible for post-kala-azar dermal leishmaniasis (PKDL). …”
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  15. 7895

    Development of therapeutic supplement using roasted-cashew-nut to protect cerebral vasoconstriction injury triggered by mixture of petroleum hydrocarbons in the hypothalamus and hi... by J.K. Akintunde, V.O. Akomolafe, R.N. Ugbaja, A.M. Olude, A.D. Folayan

    Published 2025-06-01
    “…Post treatment with RCN supplement remarkably modulated the effects by depleting the inflammatory mediators including HIF-1, p53 and MCP-1. Also, adenosinergic, purigenic and cholinergic of the hypothalamus and hippocampus were normalized by the supplement. …”
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  16. 7896

    The First Record of an Aggressive Form of Ocular Tumour Enhanced by Marek’s Disease Virus Infection in Layer Flock in Al-Najaf, Iraq by Aoula Al-Zebeeby, Ali Hadi Abbas, Haider Abas Alsaegh, Furkan Sabbar Alaraji

    Published 2024-01-01
    “…To our knowledge, this is the first record of an aggressive MD virus infection-mediated ocular tumour in a layer flock in Al-Najaf province, Iraq.…”
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  17. 7897

    Increasing Cattle Herd Size or Density in C<sub>3</sub> Grass–Legume Meadows Reduces Dietary Quality by John Derek Scasta, Fernando Forster Furquim

    Published 2025-01-01
    “…Structural equation modeling (SEM) that mediated time (i.e., Day of Year) rendered all animal number or density variables as significant predictors for CP and DOM (negative estimates) and for DOM:CP (positive estimate), indicating that congregating animals in larger groups and/or greater densities, even in meadows with high-quality forage species, may reduce post-ingestive diet quality estimates by −1.2% and −2.0 for CP and DOM for every +100 animals or for every +10 animals per hectare. …”
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  18. 7898

    Fully Inkjet-Printed Flexible Graphene–Prussian Blue Platform for Electrochemical Biosensing by Željka Boček, Marko Zubak, Petar Kassal

    Published 2025-01-01
    “…Finally, lactate oxidase was immobilized in a chitosan matrix, and the prepared biosensor exhibited analytical performance comparable to other lactate sensors found in the literature in a wide, physiologically relevant linear range for measuring lactate concentration in sweat. The development of mediator-modified electrodes with a single fabrication technology, as demonstrated here, paves the way for the scalable production of low-cost, wearable, and flexible biosensors.…”
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  19. 7899

    Enhancement of BDNF Concentration and Restoration of the Hypothalamic-Pituitary-Adrenal Axis Accompany Reduced Depressive-Like Behaviour in Stressed Ovariectomised Rats Treated wit... by Badriya Al-Rahbi, Rahimah Zakaria, Zahiruddin Othman, Asma’ Hassan, Asma Hayati Ahmad

    Published 2014-01-01
    “…In conclusion, both Tualang honey and E2 mediate antidepressive-like effects in stressed OVX rats, possibly acting via restoration of hypothalamic-pituitary-adrenal axis and enhancement of the BDNF concentration.…”
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  20. 7900

    Unravelling the multi-scale structure of vertebrate scavenger communities: The role of beta-diversity in livestock carcass consumption by María Eugenia Cabrera-García, Patricia Mateo-Tomás, José Hernán Sarasola, Juan I. Zanón Martínez, Beatriz Martínez-Miranzo, Pedro P. Olea

    Published 2025-03-01
    “…Aligning with the theory of carrion unpredictability in maintaining biodiversity, our results suggest that scavenger species replacement (turnover) at human-mediated carcasses scattered in the field plays a significant role in shaping vertebrate scavenger assemblages.…”
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