Nonpharmacological Modulation of Chronic Inflammation in Parkinson’s Disease: Role of Diet Interventions by Stefania Kalampokini, Anouck Becker, Klaus Fassbender, Epameinondas Lyros, Marcus M. Unger

“…Recent evidence suggests that neuroinflammation in PD might originate in the intestine and the bidirectional communication between the central and enteric nervous system, the so-called “gut-brain axis,” has received growing attention due to its contribution to the pathogenesis of neurological disorders. Diet targets mediators of inflammation with various mechanisms and combined with dopaminergic treatment can exert various beneficial effects in PD. …”
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On‐chip label‐free impedance‐based detection of antibiotic permeation by Jaspreet Kaur, Hamed Ghorbanpoor, Yasin Öztürk, Özge Kaygusuz, Hüseyin Avcı, Cihan Darcan, Levent Trabzon, Fatma D. Güzel

“…The results also show a clear difference between bilayer permeation that occurs through the lipidic bilayer and porin‐mediated permeation through the porin channels inserted in the lipid bilayer.…”
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Mitochondrial Mayhem: How cigarette smoke induces placental dysfunction through MMS19 degradation by Pei Zhou, Feng Jin, Shenshen Yao, Ben Sun, Ni Sun, Hongbo Guan, Xiaomei Liu

“…Transcriptome analysis indicated that dysregulation of the SMAD pathway mediates mitochondrial damage induced by MMS19 KD. …”
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Feasibility of enzalutamide on patients with recurrent non-muscle-invasive bladder cancer with marker tumors: phase I study by Takashi Kawahara, Shuya Kandori, Takahiro Kojima, Bryan J. Mathis, Masanobu Shiga, Hiroyuki Nishiyama

“…Abstract Objective Recent preclinical and retrospective clinical evidence shows that androgen receptor (AR)-mediated signals have significant roles in development of non-muscle invasive bladder cancer (NMIBC). …”
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Colorimetric Detection of Dopamine Based on Peroxidase-like Activity of β-CD Functionalized AuNPs by Sara Anderson, Hamish Shepherd, Kiran Boggavarapu, Janak Paudyal

“…We found that β-CD-AuNPs can catalyze the H₂O₂-mediated oxidation of DA. The dopamine signal-off sensor was developed by taking advantage of the peroxidase-like activity of β-CD-AuNPs towards TMB and DA, where both 3,3′,5,5′-tetramethylbenzidine (TMB) and dopamine (DA) may compete for the binding sites with β-CD-AuNPs. …”
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Sand Blocking Mechanisms and Productivity Analysis of Slant Well in Siltstone Reservoirs by Peifeng Jia, Chuanzhi Cui, Yizhong Zhao, Xiukun Wang, Yingfei Sui

“…It is proved that optimizing the filling radius of each layer can improve the production effect of mediate- and low-permeability layers. This method has been applied in Kendong #12 block. …”
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The Role of Polyphenols in Abiotic Stress Tolerance and Their Antioxidant Properties to Scavenge Reactive Oxygen Species and Free Radicals by Muhammad Junaid Rao, Bingsong Zheng

“…This review summarizes our current understanding of polyphenol-mediated stress adaptations in plants, emphasizing the regulation and function of key phenylpropanoid pathway compounds. …”
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Relationship between serum lipids and depression: A cross sectional survey among adults in Haryana, India by Rubina Mulchandani, Tanica Lyngdoh, Ria Nangia, Sukriti Singh, Sandeep Grover, JS Thakur

“…However, further investigations using prospective designs are warranted to understand this relationship and complex interactions with other mediating factors better.…”
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Black Tea May Be a Prospective Adjunct for Calcium Supplementation to Prevent Early Menopausal Bone Loss in a Rat Model of Osteoporosis by Asankur Sekhar Das, Maitrayee Banerjee, Dolan Das, Sandip Mukherjee, Chandan Mitra

“…This was found associated with enhanced activities of two relevant intestinal mucosal enzymes alkaline phosphatase (P<0.01 for duodenum, jejunum, and ileum) and Ca2+ activated ATPase (P<0.01 for duodenum, jejunum, and ileum). Such BTE-mediated promotion of calcium absorption was coupled with increase in serum estrogen titer (P<0.01) and recovery of all urinary, bone, and serum osteoporotic marker parameters, including bone histological features. …”
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Effect of opercular deformity on morphological and transcriptomic profiling of gills in golden pompano (Trachinotus ovatus) by Yuwei Wu, Qian Ma, Dihao Huang, Liuyong Wang, Qiling Zhou, Chunli Ran, Gang Chen

“…Paraffin section, Hematoxylin-Eosin (HE) staining, and TdT-mediated dUTP nick-end labeling (TUNEL) of the gills revealed that no significant difference in morphological structure or apoptosis was identified between the gills collected from the deformed and normal sides. …”
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Similarities between Tumour Immune Response and Chronic Wound Microenvironment: Influence of Mesenchymal Stromal/Stem Cells by Kimberly Thando Peta, Melvin Anyasi Ambele, Michael Sean Pepper

“…Some studies have however suggested that MSCs inhibit tumourigenesis, depending on the source of the MSCs and the specific mediators involved. Therefore, the role of MSCs in the TME appears to be complex and may result in variable outcomes. …”
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Age and moisture affect the relationship between competition and tree growth by Xinyu Han, Lushuang Gao, Mingqian Liu, Yihong Zhu, Keda Cui, Xinyu Zhang, Xiuhai Zhao, Ruibo Zhang, Klaus von Gadow, Yiyu Tian, Kangchen Wang

“…Notably, the crown, serving as a crucial organ for nutrient acquisition in trees, was a mediating factor between competition and growth. This result holds significant implications for the sustainable management of forest ecosystems in the face of a warming climate in the future.…”
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Investigation of TGFβ1-Induced Long Noncoding RNAs in Endothelial Cells by Krishna K. Singh, Pratiek N. Matkar, Adrian Quan, Laura-Eve Mantella, Hwee Teoh, Mohammed Al-Omran, Subodh Verma

“…This is the first lncRNA and mRNA transcriptome profile of TGFβ-mediated changes in human endothelial cells. These observations may reveal potential new targets of TGFβ in endothelial cells and novel therapeutic avenues for cardiovascular disease-associated endothelial dysfunction.…”
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Comparison of HER2-Targeted Antibodies for Fluorescence-Guided Surgery in Breast Cancer by Solmaz AghaAmiri, Jo Simien, Alastair M. Thompson, Julie Voss, Sukhen C. Ghosh, Servando Hernandez Vargas, Sarah Kim, Ali Azhdarinia, Hop S. Tran Cao

“…In vitro findings demonstrated HER2-mediated binding for both fluorescent immunoconjugates and were in agreement with radioligand assays using dual-labeled immunoconjugates. …”
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Binding and cleavage of pro-urokinase by a tegument extract of Fasciola hepatica newly excysted juveniles activate the host fibrinolytic system by Judit Serrat, María Torres-Valle, Carolina De Marco Verissimo, Mar Siles-Lucas, Javier González-Miguel

“…We found that F. hepatica cathepsins B3, L3, enolase and glutathione S-transferase mediate this interaction, suggesting a multifactorial or moonlighting role for these proteins. …”
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Secretion of S100A8, S100A9, and S100A12 by Neutrophils Involves Reactive Oxygen Species and Potassium Efflux by Mélanie R. Tardif, Julie Andrea Chapeton-Montes, Alma Posvandzic, Nathalie Pagé, Caroline Gilbert, Philippe A. Tessier

“…S100A8/A9 (calprotectin) and S100A12 proinflammatory mediators are found at inflammatory sites and in the serum of patients with inflammatory or autoimmune diseases. …”
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Sharing electricity over money: Third-person perspectives on human-robot dictator game outcomes by Andreea E. Potinteu, Nadia Said, Gerrit Anders, Markus Huff

“…This relationship was mediated by participant gender as well as robot related risk and opportunity perception. …”
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Translational regulation of PKD1 by evolutionarily conserved upstream open reading frames by Lei Chen, Xia Gao, Xiangshen Liu, Ye Zhu, Dong Wang

“…Our results establish PKD1 as a novel target of uORF-mediated translational regulation and mutations that perturb uORFs may dysregulate PKD1 protein level.…”
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IgG4-Related Kidney Disease: Report of a Case Presenting as a Renal Mass by Daniele Bianchi, Luca Topazio, Gabriele Gaziev, Valerio Iacovelli, Pierluigi Bove, Alessandro Mauriello, Enrico Finazzi Agrò

“…IgG4-related disease (IgG4-RD) is a nosological entity defined as a chronic immune-mediated fibro-inflammatory condition characterized by a tendency to form tumefactive, tissue-destructive lesions or by organ failure. …”
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Probiotics: Comprehensive Exploration of the Growth Promotion Mechanisms in Shrimps by Joanna Xuan Hui Goh, Loh Teng-Hern Tan, Jodi Woan-Fei Law, Kooi-Yeong Khaw, Gokhan Zengin, Kok Gan Chan, Vengadesh Letchumanan, Learn-Han Lee, Bey-Hing Goh

“…The growth promotion effect of probiotics is partly mediated through the production of bioactive compounds such as short-chain fatty acids, vitamins, and polyamines. …”
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