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7461
Exploring the Role of Artificial Intelligence on Educational Dynamics: Evaluating its Impact on Pedagogical Practices and Student Learning Outcomes
Published 2025-01-01“…The review of literature suggests role of AI in terms of profiling & prediction, tutoring, accessing student performance, grading & evaluation and personalization of learning experience which influences learning outcomes amongst students using mediating role of pedagogical beliefs of teachers. …”
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7462
Deep learning-based prediction of autoimmune diseases
Published 2025-02-01“…This study focuses on the prediction of several autoimmune diseases mediated by T cells, and proposes two models: one is the AutoY model based on convolutional neural networks, and the other is the LSTMY model, a bidirectional LSTM network model that integrates the attention mechanism. …”
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7463
The geographical variation in grassland forage quality on the eastern Qinghai-Tibet Plateau is driven mainly by climate
Published 2025-02-01“…Soil conditions indirectly affected forage quality by mediating the plant community composition. Conclusions This study highlights the role of climate in driving the variation of forage quality in the alpine grasslands. …”
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7464
From relaxed beliefs under psychedelics (REBUS) to revised beliefs after psychedelics (REBAS)
Published 2025-01-01“…We report the first empirical evidence that the relaxation and revision of negative self-belief confidence mediates psilocybin's positive psychological outcomes, and provide tentative evidence for a neuronal mechanism, namely, increased neuronal entropy. …”
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7465
Macrophages facilitate tumor cell PD‐L1 expression via an IL‐1β‐centered loop to attenuate immune checkpoint blockade
Published 2023-04-01“…Here, we revealed that interleukin (IL)‐1β was among the most abundant cytokines within the in vitro tumor‐macrophage coculture system, and enhanced IL‐1β expression was associated with impaired cytotoxicity of CD8+ T cells in human ovarian cancer, indicating the possibility that IL‐1β mediated immunosuppression during tumor‐TAMs crosstalk. …”
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7466
Increased Frequency of CD4+ CD25+ FoxP3+ T Regulatory Cells in Pulmonary Tuberculosis Patients Undergoing Specific Treatment and Its Relationship with Their Immune-Endocrine Profil...
Published 2015-01-01“…Since regulatory T cells (Tregs) are relevant in IR regulation, we analyzed Tregs variations throughout the course of TB treatment and its relationship with changes in immune-endocrine mediators dealing with disease immunopathology. The cohort was composed of 41 adult patients, 20 of them completing treatment and follow-up. …”
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7467
Arterial Hypertension and Interleukins: Potential Therapeutic Target or Future Diagnostic Marker?
Published 2019-01-01“…Complex immune responses are involved in the inflammatory mechanism of hypertension, with evidence pointing to increased inflammatory mediators even in prehypertensive patients. Increased vascular permeability, thrombogenesis, and fibrosis, effects that are associated with sustained hypertension, could be attributed to chronic inflammation. …”
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7468
AI anxiety: Explication and exploration of effect on state anxiety when interacting with AI doctors
Published 2025-03-01“…Furthermore, based on the status quo bias theory and an adaptation of the theory of interactive media effects (TIME) for the study of human-AI interaction (HAII), this study hypothesizes that the affect heuristic triggered by state anxiety would mediate the causal relationship between the source cue of a doctor and user experience (UX) as well as behavioral intentions. …”
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7469
CXC chemokine receptor 7 ameliorates renal fibrosis by inhibiting β-catenin signaling and epithelial-to-mesenchymal transition in tubular epithelial cells
Published 2024-12-01“…In this study, we investigated the potential role of CXCR7 in mediating renal fibrosis. CXCR7 expression is decreased in unilateral ischemia–reperfusion injury (UIRI) and unilateral ureteral obstruction mouse models. …”
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7470
Peran guru dalam mewujudkan lingkungan sekolah zero bullying terhadap kesehatan mental siswa sekolah dasar
Published 2024-08-01“…Guru bertindak sebagai mediator dan fasilitator adalah guru bertindak dengan memberikan pendampingan dan bimbingan kepada siswa yang terlibat dalam situasi bullying serta memberikan pemahaman kepada siswa mengenai zero bullying menggunakan sumber belajar yang berkaitan dengan bullying; guru sebagai penasihat bertindak memberikan nasehat terkait bullying dengan cara yang mendidik, mendukung, dan proaktif terhadap siswa; serta guru sebagai pembimbing bagi siswa memberikan edukasi kepada para siswa mengenai bullying serta dampaknya dan guru mengadakan diskusi, ceramah, untuk meningkatkan pemahaman siswa tentang perlunya membentuk lingkungan yang aman di SDN 76 Pekanbaru sehingga dapat menjamin Kesehatan mental siswa di sekolah.…”
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7471
The ultradian rhythm of glucocorticoid secretion and the time course of target gene regulation
Published 2015-07-01“…The results of these experiments clearly demonstrate that ultradian stimulation by natural hormones induces rapid GR exchange with glucocorticoid response elements and leads to cyclic GR mediated transcriptional regulation (gene pulsing) at the level of nascent RNA. …”
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7472
MoS<sub>2</sub>–Plasmonic Hybrid Platforms: Next-Generation Tools for Biological Applications
Published 2025-01-01“…This review explores various synthesis strategies for MoS<sub>2</sub>–plasmonic hybrids, including seed-mediated growth, in situ deposition, and heterojunction formation, which enable tailored configurations optimized for specific biological applications. …”
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7473
The histone demethylase KDM5C enhances the sensitivity of acute myeloid leukemia cells to lenalidomide by stabilizing cereblon
Published 2025-01-01“…Abstract Background The protein cereblon (CRBN) mediates the antileukemia effect of lenalidomide (Len). …”
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7474
Somatic copy number deletion of chromosome 22q in papillary thyroid carcinoma
Published 2025-01-01“…These findings highlight the value of further investigations into the contributions of 22qDEL events to PTC, perhaps mediated through immune perturbations.…”
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7475
Disrupted Endothelial Cell Layer and Exposed Extracellular Matrix Proteins Promote Capture of Late Outgrowth Endothelial Progenitor Cells
Published 2016-01-01“…The interaction was mediated by integrins α5β3, αvβ1, and αvβ3. This study has demonstrated that an injured local environment presents sufficient adhesive signals to capture flow perfused LO-EPC in vitro and that LO-EPC have properties consistent with their potential role in vascular repair.…”
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7476
Anisodamine ameliorates crystalline silica-exposed pulmonary inflammation and fibrosis via the α7nAChR/JAK2/STAT3 signaling pathway
Published 2025-01-01“…The results suggest that ANI may alleviate silicosis by inhibiting pulmonary inflammation and fibrosis through modulation of the JAK2/STAT3 signaling pathway, which is mediated by α7nAChR. Coal workers can utilize ANI early on to treat and prevent silicosis.…”
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7477
Comparison of natural and artificial vasopressin deficiency: why the latter is lethal?
Published 2016-05-01“…Comparing available knockout models we can conclude that the combined V1a and V2 receptor mediated effects, namely hypotension and water lost together may led to lethality. …”
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7478
CD14loCD301b+ macrophages gathering as a proangiogenic marker in adipose tissues
Published 2025-01-01“…Because Igf1 expression has been suggested to be associated with Cd301b expression through pseudotime analysis, we found it was insulin-like growth factor 1 secreted from Cd14−/− macrophages that mediated the angiogenesis enhancement. Collectively, our findings indicate that CD14 deficiency increased the accumulation of CD14loCD301b+ macrophages in ATs, which may serve as a proangiogenic marker, providing novel insights into the relationship between CD14 and obesity development.…”
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7479
Targeted allele-specific FGFR2 knockdown via human recombinant ferritin nanoparticles for personalized treatment of Crouzon syndrome
Published 2025-03-01“…Here, we show that ferritin-mediated AS FGFR2 knockdown by siRNA represents a suitable strategy to dampen FGFR2 overactivation in patients’ cells.…”
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7480
Perceptual service robot attributes affecting customer value co-creation intention in luxury hotels industry
Published 2025-02-01“…Moreover, the customer hospitality experience serves as a significant mediator, implying the anthropomorphism, as the most critical attribute.…”
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