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7361
Le national à distance. Circulation de normes et réécriture du politique de la Tunisie
Published 2016-06-01“…The experience of such agents mediating between the shores of experience, and their political acculturation in the conception and practice of politics will have a distinct effect on constitutional processes. …”
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7362
Review on the Role of Host Immune Response in Protection and Immunopathogenesis during Cutaneous Leishmaniasis Infection
Published 2020-01-01“…In addition, some studies have also indicated that CD8+ T cells play a vital role in immune defense through cytokine production and their cytotoxic activity and excessive production of proinflammatory mediators promote amplified recruitment of cells. This could be correlated with excessive inflammatory reaction and ultimately resulted in tissue destruction and development of immunopathogenesis. …”
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7363
Effects of 0.01 mM strontium on human periodontal ligament stem cell osteogenic differentiation via the Wnt/-catenin signaling pathway
Published 2025-02-01“…A 0.01 mM Sr 2+ concentration significantly enhanced hPDLSC proliferation and osteogenic differentiation. However, XAV939-mediated inhibition of the canonical Wnt/β-catenin pathway could reverse the Sr 2 + -induced osteogenic effects. …”
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7364
Isoferulic acid facilitates effective clearance of hypervirulent Klebsiella pneumoniae through targeting capsule.
Published 2025-01-01“…In this way, IFA remarkably reduced capsule thickness and impaired hypercapsule-associated hypermucoviscosity phenotype (HMV), thereby significantly sensitizing hvKP to complement-mediated bacterial killing and accelerating host cell adhesion and phagocytosis. …”
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7365
Antigen Presentation in the Gut
Published 1990-01-01“…Suppressor T cells and unresponsive T helper cells in the mucosa appear to mediate systemic T cell tolerance of dietary antigens. …”
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7366
Immune Responses to Tissue-Restricted Nonmajor Histocompatibility Complex Antigens in Allograft Rejection
Published 2017-01-01“…., cross-matching) to detect antibodies (Abs) against donor human leukocyte antigens, which has been shown to reduce Ab-mediated hyperacute rejection. However, primary allograft dysfunction and rejection still occur frequently. …”
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7367
Introduction risk of fire ants through container cargo in ports: Data integration approach considering a logistic network.
Published 2025-01-01“…Unlike natural dispersal, methods to address these issues have not yet been established, because the spatial correlation between ports based on the geographical distance is not assumed for human-mediated species introduction through container cargo. …”
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7368
Scaffolded Antigens in Yeast Cell Particle Vaccines Provide Protection against Systemic Polyoma Virus Infection
Published 2016-01-01“…Conversion to Yeast Cell Particle (YCP) vaccines by partial removal of surface mannoproteins exposes β-glucan, mediating efficient uptake by antigen-presenting cells (APCs). …”
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7369
Occurrence of Fatal and Nonfatal Adverse Outcomes after Heart Transplantation in Patients with Pretransplant Noncytotoxic HLA Antibodies
Published 2013-01-01“…Of the subgroup of 37 patients suspected for antibody mediated rejection (AMR), the 9 with pretransplant HLA ab were more likely to display pathological AMR grade 2 (P=0.04). …”
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7370
Metal-organic frameworks-derived CaO/ZnO composites as stable catalysts for biodiesel production from soybean oil at room temperature
Published 2025-01-01“…This study introduces MOF-mediated synthesis (MOFMS) of heterogeneous catalysts, specifically CaO@ZnO and ZnO@CaO nanocomposites, from inexpensive and non-toxic metal salts and linkers in water. …”
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7371
A charge reversal nano-assembly prevents hepatic steatosis by resolving inflammation and improving lipid metabolism
Published 2025-03-01“…Here we propose a charge reversal fullerene based nano-assembly to migrate hepatic steatosis via inhibiting macrophage-mediated inflammation and normalizing hepatocellular lipid metabolism in obesity mice. …”
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7372
Enhanced effects of slowly co-released TGF-β3 and BMP-2 from biomimetic calcium phosphate-coated silk fibroin scaffolds in the repair of osteochondral defects
Published 2024-07-01“…Here, we demonstrated that the biomimetic calcium phosphate coating system (BioCaP) could effectively uptake and slowly release the incorporated bioactive agents compared to the surface absorption system via osteoclast-mediated degradation of BioCaP coatings. The release kinetics were determined as a function of time. …”
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7373
Blocking TNF-α Reduces <i>Leishmania major</i>-Induced Hyperalgesia and Changes the Cytokine Profile in the Paw Skin of BALB/c Mice with a Potential Positive Effect on Parasite Cle...
Published 2024-12-01“…These and other cytokines also play a major role in <i>Leishmania</i>-induced hyperalgesia via two possible pathways, one involving prostaglandins and the other sympathetic amines as final mediators, preceded by a cascade of cytokines, among which TNF-α seems to play a pivotal role via a still unclear mechanism of action. …”
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7374
Rat Strain Differences in Susceptibility to Alcohol-Induced Chronic Liver Injury and Hepatic Insulin Resistance
Published 2010-01-01“…The finding of more severe steatohepatitis in alcohol fed Long Evans (LE) compared with Sprague Dawley (SD) and Fisher 344 (FS) rats prompted us to determine whether host factors related to alcohol metabolism, inflammation, and insulin/IGF signaling predict proneness to alcohol-mediated liver injury. Adult FS, SD, and LE rats were fed liquid diets containing 0% or 37% (calories) ethanol for 8 weeks. …”
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7375
Protective factors contributing to the health status of construction industry migrant workers in Chinese mainland
Published 2025-01-01“…Social support fully mediated the association between education level and mental health. (6) Education level, marital adjustment, and social support were all protective factors contributing to the health status of CIMWs.…”
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7376
Cervical heterotopic heart transplantation in mice using a novel suture technique
Published 2025-02-01“…Background: Vascularized transplantation models in mice are critical to understand mechanisms that mediate rejection and to develop new therapeutics. …”
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7377
Innovative immunotherapies and emerging treatments in type 1 diabetes management
Published 2025-01-01“…Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease characterized by the selective destruction of pancreatic insulin-producing beta cells, primarily mediated by CD4+ and CD8+ T cells. This review comprehensively examines the latest advances in immunotherapeutic approaches to T1D, categorizing current strategies into four main groups: antigen-independent therapies, antigen-dependent therapies, beta cell therapies, and stem cell therapies. …”
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7378
Exercise induces dynamic changes in intra-articular metabolism and inflammation associated with remodeling of the infrapatellar fat pad in mice
Published 2025-01-01“…Abstract We hypothesized that daily exercise promotes joint health by upregulating anti-inflammatory mediators via adaptive molecular and metabolic changes in the infrapatellar fat pad (IFP). …”
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7379
A mechanistic overview on green assisted formulation of nanocomposites and their multifunctional role in biomedical applications
Published 2025-02-01“…This review encapsulates the current development in the formulation of plant-mediated nanocomposites by using several plant species and the impact of secondary metabolites on their biocompatible functioning. …”
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7380
Tissue-Related Hypoxia Attenuates Proinflammatory Effects of Allogeneic PBMCs on Adipose-Derived Stromal Cells In Vitro
Published 2016-01-01“…ASC/PBMCs interaction resulted in anti-inflammatory shift of paracrine mediators in conditioning medium with significant increase of immunosuppressive LIF level. …”
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