Rimegepant for the treatment of migraine by Amnon A. Berger, Ariel Winnick, Austin H. Carroll, Alexandra Welschmeyer, Nathan Li, Marc Colon, Antonella Paladini, Giovanni F. Ramírez, Jamal Hasoon, Elyse M. Cornett, Jaehong Song, Giustino Varrassi, Adam M. Kaye, Alan D. Kaye, Latha Ganti

“…The trigeminovascular system is now known to have a significant role in the initiation of migraines, including the release of pain mediators such as CGRP and substance P. Traditional treatment of migraine is usually divided into acute and preventive treatment. …”
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Mortality Clustering in the Family. Fast Life History Trajectories and the Intergenerational Transfer of Infant Death in Late 19th- and Early 20th-Century Antwerp, Belgium by Robyn Donrovich, Paul Puschmann, Koen Matthijs

“…These results remained robust after controlling for potential mediating and moderating factors. The results on the age of the mother at birth, her marital status, as well as the living environment suggest that at least part of the intergenerational transfer in infant mortality can be explained on the basis of life history theory: women who grew up in a high-risk family tended to reproduce earlier and faster, and often raised their children without a partner. …”
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Rafraîchir les observatoires par le son by Cécile Regnault, Patrick Romieu

“…These coextensive heterogeneities of sound media require theoretical and methodological rigour on the part of collective organisations in charge of their mediations.…”
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Parkinson’s disease and exosomes: from pathogenesis to diagnosis and treatment by A. Mišeikaitė, P. Vaitkienė

“…There is growing evidence of the importance of exosomes for cell-to-cell communication, mediating the exchange of biological information and substances, and the ability to cross the blood-brain barrier. …”
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An alternative perspective on the relationship between multiscale built environments and walking behavior: evidence from the government-subsidized resettlement towns in China by Jieqiong Wang, Jing Huang

“…Moreover, socio-environmental perception plays a full mediating role in the association between objective built-environment factors and walking behavior but plays a partial role in the association between sociodemographic factors and walking behavior. …”
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Neutrophil-to-lymphocyte ratio: A biomarker for predicting systemic involvement in iga vasculitis by Rintu Merin George, Arun C Inamadar, Ajit B Janagond

“…Context:“IgA vasculitis, is an immune complex mediated, self limited cutaneous small vessel vasculitis, characterized by palpable purpurae, arthralgia or arthritis, gastrointestinal and/or renal involvement.” …”
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Multi-tissue characterization of the constitutive heterochromatin proteome in Drosophila identifies a link between satellite DNA organization and transposon repression. by Ankita Chavan, Lena Skrutl, Federico Uliana, Melanie Pfister, Franziska Brändle, Laszlo Tirian, Delora Baptista, Dominik Handler, David Burke, Anna Sintsova, Pedro Beltrao, Julius Brennecke, Madhav Jagannathan

“…We further demonstrate that this gonadal atrophy can be rescued by mutating the checkpoint kinase, Chk2, which mediates germ cell arrest in response to transposon mobilization. …”
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Examining the Relationship between Middle School Students’ Critical Reading Skills, Science Literacy Skills and Attitudes: A Structural Equation Modeling by Ersin Karademir, Ufuk Uluçınar

“…It has been revealed that science literacy skill, which exists in the model, acts as partial mediating variable. As a result, as put forward in theory, critical thinking, critical reading skill, and science literacy skills and attitudes have been found to be closely related. …”
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Mortality Clustering in the Family. Fast Life History Trajectories and the Intergenerational Transfer of Infant Death in Late 19th- and Early 20th-Century Antwerp, Belgium by Robyn Donrovich, Paul Puschmann, Koen Matthijs

“…These results remained robust after controlling for potential mediating and moderating factors. The results on the age of the mother at birth, her marital status, as well as the living environment suggest that at least part of the intergenerational transfer in infant mortality can be explained on the basis of life history theory: women who grew up in a high-risk family tended to reproduce earlier and faster, and often raised their children without a partner. …”
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Dexmedetomidine Mitigates Microglial Activation Associated with Postoperative Cognitive Dysfunction by Modulating the MicroRNA-103a-3p/VAMP1 Axis by Zhichao Wu, Han Wang, Zuan Shi, Yalan Li

“…Surgery-induced microglial activation is critical in mediating postoperative cognitive dysfunction (POCD) in elderly patients, where the important protective effect of dexmedetomidine has been indicated. …”
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Optimization of Enzymatic Hydrolysis by Protease Produced from Bacillus subtilis MTCC 2423 to Improve the Functional Properties of Wheat Gluten Hydrolysates by Hari Prasath Rajendhran, Vinoth Kumar Vaidyanathan, Swethaa Venkatraman, Pothiyappan Karthik

“…The percentage of free amino acids obtained by protease-mediated hydrolysates increased significantly compared to the unhydrolyzed wheat, which was observed by high-performance liquid chromatography. …”
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The role of workplace safety and personal contribution in sustaining work ability: A pilot study among Italian preschool teachers by Gloria GUIDETTI, Sara VIOTTI, Ilaria SOTTIMANO, Giulia BACCI, Daniela CONVERSO

“…Results: Based on Structural Equation Modeling (χ2(df = 32) = 47.021, p < .01, χ2/df =1.46, CFI = .98, TLI=.97, RMSEA = .06 (90% CI: .02, .10), SRMR = .05), all hypotheses were confirmed, highlighting that the relationship between workplace safety and work ability was positive and fully mediated by preschool teachers' personal contribution to safety (indirect effect CI 95%: 0.037- 1.094). …”
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A Novel Paramagnetic Substrate for Detecting Myeloperoxidase Activity in Vivo by Mohammed S. Shazeeb, Yang Xie, Suresh Gupta, Alexei A. Bogdanov

“…Bis-HTrp-DTPA(Gd) should offer improvements for MR! of MPO-mediated inflammation in vivo, especially in high-field MR!…”
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Normalization of Deviant Behavior in Muc2+/+ Mice through Dietary Incorporation of Bacillus subtilis Spores by Maryana Morozova, Alexander Alekseev, Arsalan Saeidi, Ekaterina Litvinova

“…Changes in cytokines, serotonin, and tyrosine levels may mediate the normalizing impact of B. subtilis spores on Muc2+/+ mice behavior. …”
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Optimized rice transformation protocol for transformation of the blast susceptible Indica rice accession CO39 by Julian R. Greenwood, Anna N. Glaus

“…Results Following the aforementioned transformation protocol, calli browning occurred and no Agrobacterium-mediated transformation could be achieved, but this could be remedied by increasing the concentration of l-Proline. …”
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A Severe Case of Overlap of Morphea and Eosinophilic Fasciitis after Burn Injuries by Hania Sami, Faria Sami, Shahzad Ahmed Sami, Abdulqadir J. Nashwan

“…Another uncommon immune-mediated connective tissue disease called eosinophilic fasciitis (EF) evolves to cause sclerosis and woody skin induration. …”
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Towards a green world: how new urbanization affects green total factor carbon productivity by Xiaohong Wang, Xuanting Li

“…IntroductionNew urbanization is a powerful support for regional economic growth and green transformation.MethodsIn this paper, we select data from 237 cities at prefecture level and above in China from 2010 to 2021 for quasi-experimental design, and investigate the effects of new urbanization policy pilots on urban green total factor productivity (GTFP) and its mechanism by constructing a multi-period difference-in-differences model.ResultsThe study finds that: a) the construction of new urbanization has a positive impact on promoting urban GTFP, and this result is verified by a series of robustness tests; b) the promotion of industrial structure upgrading, the facilitation of green technological innovation, and the reduction of the degree of resource mismatch all partially mediate the relationship between new urbanization and urban GTFP; c) environmental regulation and market integration both modulate the relationship between the construction of new urbanization and urban GTFP in positive directions; d) heterogeneity analysis shows that, in terms of the two-dimensional city attributes of ‘location-characteristics’, the increase in GTFP is more significant in eastern and central cities, and in non-resource cities; e) further analysis shows that the pilot policies of new urbanization have a spatial spillover effect on GTFP, and the policy spillover effects are mainly affected through mechanisms such as industrial structure upgrading in neighboring municipalities.DiscussionThis study provides new ideas for the next stage of sustainable regional green development in China, thus promoting China's high-quality development with theoretical and practical significance.…”
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Global Warming, Air Pollution and Health by Robin Attfield

“…Some of these impacts could be described as ‘direct’, in the form of fatalities and illnesses due to the increasingly frequent heatwaves in many countries of recent years, ascribable to anthropogenic climate change. Other impacts are mediated through the air pollution that results from emissions from vehicles in the form of a cocktail of carbon oxides including carbon monoxide, nitrogen dioxide and particulates. …”
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Violence and Memory in the Multiple Versions of Claudia Rankine’s Citizen by John K. Young

“…It explores the multiple iterations of Citizen through Daniel Ferrer’s distinctions between variant and variation, finding Rankine’s work an exemplary case of the ways in which, as Kinohi Nishikawa has recently argued, “race is not an a priori category to be read into literature, but a complex effect of distinct social, cultural, and textual mediations.”…”
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A Review of Risk Factors and Predictors for Hemorrhagic Transformation in Patients with Acute Ischemic Stroke by Sneha E. Thomas, Noorine Plumber, Priyanka Venkatapathappa, Vasavi Gorantla

“…Current research into inflammatory mediators and biomarkers such as Cyclooxygenase-2, matrix metalloproteinases, and soluble ST2 and their potential role as treatment options for HT is also briefly discussed. …”
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