The Effects of Dipeptidyl Peptidase-4 Inhibitors on Cardiovascular Disease Risks in Type 2 Diabetes Mellitus by Pegah Yousefzadeh, Xiangbing Wang

“…These agents may have the potential to lower blood pressure, improve lipid profile and endothelial dysfunction, decrease the macrophage-mediated inflammatory response, and prevent myocardial injury. …”
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Polymer Gels Based on PAMAM Dendrimers Functionalized with Caffeic Acid for Wound-Healing Applications by Ricardo I. Castro, Wendy Donoso, Franko Restovic, Oscar Forero-Doria, Luis Guzman

“…Additionally, the ability to activate molecular mediators of the healing process was evidenced. Furthermore, GPG3Ca potentiated the in vivo wound-healing process. …”
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HIV-1 Replication in HIV-Infected Individuals Is Significantly Reduced When Peripheral Blood Mononuclear Cells Are Superinfected with HSV-1 by Taneth Yamsuwan, Chintana Chirathaworn, Pokrath Hansasuta, Parvapan Bhattarakosol

“…This study investigated HSV-1 replication in PBMCs from 25 HIV-infected individuals and 15 healthy donors and the effects of HSV-1 superinfection on HIV-1 production. Herpes viral entry mediator (HVEM) receptor on T lymphocytes was also evaluated. …”
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STAT1, IGF1, RAC1, and MDM2 Are Associated with Recurrence of Giant Cell Tumor of Bone by Shuxin Chen, Zepeng Du, Bingli Wu, Huiyang Shen, Chunpeng Liu, Xueli Qiu, Yufeng Zhang, Liyan Xu, Enmin Li, Zhigang Zhong

“…Functional enrichment analysis showed that this network involves many important biological progress mediated by these four genes, including immune response. …”
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Quality of Life in Painful Peripheral Neuropathies: A Systematic Review by Ayesha Girach, Thomas Henry Julian, Giustino Varrassi, Antonella Paladini, Athina Vadalouka, Panagiotis Zis

“…Other aetiologies of painful PN where QoL has been studied to date include gluten, immune-mediated, HIV, chemotherapy-induced, and chronic idiopathic axonal polyneuropathy. …”
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Computational design of multi-epitope vaccine against Hepatitis C Virus infection using immunoinformatics techniques. by Sara Zubair, Fahed Parvaiz, Turki Abualait, Khalid Al-Regaiey, Tasneem Anwar, Mahnoor Zafar, Imdad Kaleem, Shahid Bashir

“…Nevertheless, attempts to mediate clinically relevant anti-HCV activity in people have mainly failed, despite the vaccines present satisfactory progress. …”
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Alteration in the Cytokine Secretion of Bone Marrow Stromal Cells from Patients with Chronic Myelomonocytic Leukemia Contribute to Impaired Hematopoietic Supportive Activity by Hui Shi, Yingshao Wang, Rong Li, Wen Xing, Feng-Chun Yang, Jie Bai, Yuan Zhou

“…To assess whether the altered cytokine secretion was one of the mechanisms to mediate the impaired hematopoietic supportive activity of CMML-BMSCs, a transwell coculture followed by cytokine array was performed. …”
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IL-34 Suppresses Candida albicans Induced TNFα Production in M1 Macrophages by Downregulating Expression of Dectin-1 and TLR2 by Rong Xu, Hong-Fan Sun, David W. Williams, Adam V. Jones, Ali Al-Hussaini, Bing Song, Xiao-Qing Wei

“…The molecular mechanism of IL-34 mediated suppression of HKC induced TNFα production by M1 macrophages was by the inhibition of M1 macrophage expression of key C. albicans pattern recognition receptors (PPRs), namely, Toll-like receptor (TLR) 2 and Dectin-1. …”
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FutureMS cohort profile: a Scottish multicentre inception cohort study of relapsing-remitting multiple sclerosis by David Hunt, Siddharthan Chandran, Peter Connick, Peter Foley, Patrick K A Kearns, Sergio E Baranzini, Adam D Waldman, Sarah J Martin, Elizabeth Freyer, F J Carod-Artal, Lee Murphy, Amy Stenson, Jessie Chang, Rozanna Meijboom, Elizabeth N York, Yingdi Chen, Christine Weaver, Katarzyna Hafezi, Stacey Thomson, Adil Harroud, Margaret McLeod, Jonathon O'Riordan, Niall J J MacDougall

“…Purpose Multiple sclerosis (MS) is an immune-mediated, neuroinflammatory disease of the central nervous system and in industrialised countries is the most common cause of progressive neurological disability in working age persons. …”
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Possible Role of Interaction between PPARα and Cyclophilin D in Cardioprotection of AMPK against In Vivo Ischemia-Reperfusion in Rats by Giselle Barreto-Torres, Sabzali Javadov

“…However, it is unclear whether beneficial effects of AMPK are mediated through the PTP and, if they are not, whether simultaneous activation of AMPK and inhibition of the PTP exert synergistic protective effects against cardiac IR injury. …”
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The effect of drought stress on Pinellia ternata in terms of physiology and aquaporin genes after Arbuscular mycorrhizal fungal inoculation by Shuang Li, Yajun Liu, Han He, Yike Xu, Xiaochun Sun, Wenjing Huang

“…Our study highlights the effect of AMF on P. ternata under drought stress by mediating physiological and biochemical activities. …”
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Stress and arterial hypertension: ISIAH rat strain by Ye. V. Antonov, Yu. V. Alexandrovich, A. A. Seryapina, L. O. Klimov, A. L. Markel

“…Even in the cases when one managed to obtain a signi­ficant hypertensive effect in experimental studies with emotional stress, it was difficult to explain the mechanisms mediating the formation of stressinduced hypertension. …”
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Environmentally specific empowering leadership and organisational citizenship behaviour toward the environment: The roles of green work engagement, psychological ownership and envi... by Khutso Pitso Mankgele, Olawale Fatoki

“…A theoretical framework posits that environmentally specific empowering leadership enhances OCBE, with psychological ownership and green work engagement acting as mediating variables. Furthermore, environmental concern among co-employees moderates this relationship. …”
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The Iron-Klotho-VDR Axis Is a Major Determinant of Proximal Convoluted Tubule Injury in Haptoglobin 2-2 Genotype Diabetic Nephropathy Patients and Mice by Inbal Dahan, Nadia Thawho, Evgeny Farber, Nakhoul Nakhoul, Rabea Asleh, Andrew P. Levy, Yan Chun Li, Ofer Ben-Izhak, Farid Nakhoul

“…In conclusion, the iron-klotho-VDR axis is a major player in the mechanism contributing to iron-mediated PCT injury in diabetic Hp 2-2 mice and patients. …”
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Digital Storytelling: Resistive Stories and the “Measurement” of Change by Thas Angela M. Kuga

“…What form the final narrative takes in any digital storytelling project is often shaped by the interests of these “mediators” who turn “judges of narratives” when they mould and package these stories to be more palatable to their specific audiences and consumption needs. …”
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Christianity, ‘supernatural’ beliefs and COVID-19 by E. Shoko

“…Issues around social distancing and lockdown directly impacted articulation and religious expression, while understanding of the pandemic and the virus were mediated through constructions of religio-spiritual beliefs. …”
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Caffeine-Induced Suppression of GABAergic Inhibition and Calcium-Independent Metaplasticity by Masako Isokawa

“…Time course of suppression and the subsequent recovery of IPSCs resembled DSI (depolarization-induced suppression of inhibition), mediated by endogenous cannabinoids that require a [Ca2+]i rise. …”
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How Bacteria-Induced Apoptosis of Intestinal Epithelial Cells Contributes to Mucosal Inflammation by Martin Hausmann

“…Microbiota can both induce or inhibit apoptosis of intestinal epithelial cells thus contribute to mucosal inflammation or support epithelial integrity respectively. Bacteria-mediated cytokine secretion and altered cell signalling are central to epithelial injury. …”
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Two mechanisms of membrane digestion: enzymatic-transport ensemble exists for oligopeptides as well by S. T. Metelsky, V. T. Ivashkin

“…To determine, which mechanism of dipeptide transport is realized under experimental conditions: PEPT1-mediated transport of the intact dipeptides or transport of the amino acid formed as a result of membrane hydrolysis of dipeptides through transport systems for free amino acid.Material and methods. …”
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Daring to Be Different: The First-Person HIV-Positive Narrator in Two South African Novels by Lizzy Attree

“…The shifts and continuities in the representation of HIV/AIDS found between these two novels, published 18 years apart, seem to disrupt the trajectory of the post-colonial bildungsroman as it is mediated (for the first time?) through the HIVpositive narrator. …”
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