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7181
Influence of Febrile Neutropenia Period on Plasma Viscosity at Malignancy
Published 2013-01-01“…Despite normal values of various parameters known to trigger plasma viscosity, particularly fibrinogen, it can be easily argued that the main mechanism may be the endothelial injury during infectious process and immune response mediated microcirculatory blood flow alterations.…”
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7182
Metagenomic insights into pathogenic bacteria and antimicrobial resistance in offshore coastal sediments – An example from Gulf waters
Published 2025-04-01“…The environment-mediated spread of antimicrobial resistance (AMR) has become a serious public health issue. …”
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7183
Targeted nanoliposomes for precision rheumatoid arthritis therapy: a review on mechanisms and in vivo potential
Published 2025-12-01“…Furthermore, the targeting strategies of pH-sensitive, flexible, surface-modified, PEGylated, acoustic, ROS-mediated, and biofunctionalized liposomes are addressed. …”
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7184
Renal Protection by Genetic Deletion of the Atypical Chemokine Receptor ACKR2 in Diabetic OVE Mice
Published 2016-01-01“…The atypical chemokine receptor ACKR2 is a chemokine scavenger receptor which binds and sequesters many inflammatory CC chemokines but does not transduce typical G-protein mediated signaling events. ACKR2 is known to regulate diverse inflammatory diseases but its role in DN has not been tested. …”
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7185
Binding Orientations and Lipid Interactions of Human Amylin at Zwitterionic and Anionic Lipid Bilayers
Published 2016-01-01“…In this study, as a first step to understand the mechanism of membrane-mediated hIAPP aggregation, we investigate the binding behaviors of hIAPP monomer at zwitterionic palmitoyloleoyl-phosphatidylcholine (POPC) bilayer by performing atomistic molecular dynamics simulations. …”
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7186
Family, friends, and financial know-how: influences on students' intentions to pursue entrepreneurship, with the moderating role of self-efficacy
Published 2024-12-01“…Economic literacy was found to mediate the influence of family economic education and peer groups on entrepreneurial intentions. …”
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7187
Collaborative modification strategy to improve the formation of biochar-derived persistent free radicals for aniline removal via peroxymonosulfate activation
Published 2025-01-01“…These findings provide valuable insights into the mechanisms of PFR-mediated catalytic oxidation, highlighting the key roles of pyridinic rings, with or without oxygenated groups, in enhancing catalytic performance of biochar. …”
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7188
Non-invasive physical plasma improves conventional wound management of cut and bite wounds in wild European hedgehogs
Published 2025-01-01“…The therapeutic effect is mediated by reactive oxygen species (ROS). Based on the biomedical effects known to date, it can be assumed that NIPP can also be used for wound treatment in non-human mammals. …”
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7189
Comprehensive analysis of differential mRNA and circRNA profiles in primary and metastatic pancreatic neuroendocrine tumors
Published 2025-03-01“…Overall, our research indicates that the SKAP1-mediated pathway is crucial in pNET development and metastasis.…”
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7190
Cytokine-armed oncolytic herpes simplex viruses: a game-changer in cancer immunotherapy?
Published 2024-05-01“…Oncolytic viruses are agents that mediate antitumor activity by directly killing tumor cells and inducing immune responses. …”
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7191
Beneficial Effects of Capybara Oil Supplementation on Steatosis and Liver Apoptosis in Obese Mice
Published 2024-01-01“…Polyunsaturated fatty acids (PUFA) are lipid mediators that have anti-inflammatory characteristics and can be found in animals and plants, with capybara oil (CO) being a promising source. …”
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7192
CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases
Published 2012-01-01“…Increased oxidative stress from induction of CYP2E1 sensitizes hepatocytes to LPS and TNFα toxicity and oxidants, activation of inducible nitric oxide synthase and p38 and JNK MAP kinases, and mitochondrial dysfunction are downstream mediators of this CYP2E1-LPS/TNFα-potentiated hepatotoxicity. …”
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7193
Labeling tumor-associated extracellular vesicles with antibody-DNA conjugates for quantitative analysis
Published 2025-01-01“…Simultaneously, DNA in the conjugate is attached to the surfaces of TAEs and holds the signal amplification post, converting protein identities to DNA amplification for protein detection, even at the molecular level.ResultsThese findings revealed that TAEs can be quantitatively detected using DNA-mediated quantitative polymerase chain reaction (qPCR). …”
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7194
Characterization and Etiopathogenic Approach of Pediatric Renal Biopsy Patients in a Colombian Medical Center from 2007-2017
Published 2018-01-01“…The most prevalent biopsy diagnosis was glomerulonephritis (44%) and among these patients, glomerulonephritis mediated by immune complexes was the most frequent pathogenic type (90.5%). …”
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7195
Improving explainability of post-separation suicide attempt prediction models for transitioning service members: insights from the Army Study to Assess Risk and Resilience in Servi...
Published 2025-01-01“…This report presents results of an attempt to refine the model to address these limitations by re-estimating the model in a larger sample (n = 5909) and attempting to develop embedded models for differential risk of post-separation stressful life events (SLEs) known to mediate the association of model predictions with post-separation nonfatal suicide attempts (SAs; n = 4957). …”
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7196
Long-Range Optomechanical Interactions in SiN Membrane Arrays
Published 2025-01-01“…Photons bounce back and forth inside a high-finesse Fabry-Pérot cavity and mediate the interaction between multiple membranes over a significant distance compared to the wavelength. …”
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7197
Role of glucocorticoid receptor expression in Chronic Chagas Cardiomyopathy: implications for inflammation and cardiac hypertrophy
Published 2025-01-01“…Recent data also suggest an association with altered regulation of glucocorticoid (GC)-mediated circuits failing to control systemic inflammation. …”
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7198
PPAR Agonists and Cardiovascular Disease in Diabetes
Published 2008-01-01“…Many of these potentially anti-atherosclerotic effects are thought to be mediated by transrepression of nuclear factor-kB, STAT, and activator protein-1 dependent pathways. …”
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7199
The Impact of Enterprise Resource Planning on Operational Performance through Supply Chain Orientation in Faradaneh Company
Published 2023-10-01“…The questionnaire was implemented through the participation of 135 managers and employees of Faradana company who were selected by stratified random sampling after measurement of validity (face and content validity based on Lawshe's method, confirmatory and exploratory factor analysis, convergence, and divergence) and reliability (Cranach's alpha method and hybrid).Findings: The results showed that ERP had a significant and strong effect on the OP of Faradaneh company by mediating the SCO, indicating the high predictive power of the ERP components (With a coefficient of determination of 0.93). …”
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7200
Postnatal Growth Patterns in a Chilean Cohort: The Role of SES and Family Environment
Published 2012-01-01“…This study examined how family environmental characteristics served as mediators in the relationship between socioeconomic conditions and infant growth in a cohort of Chilean infants. …”
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