The role of the interplay between macrophage glycolytic reprogramming and NLRP3 inflammasome activation in acute lung injury/acute respiratory distress syndrome by Lan Luo, Xiaoli Zhuang, Lin Fu, Ziyuan Dong, Shuyuan Yi, Kan Wang, Yu Jiang, Ju Zhao, Xiaofang Yang, Feilong Hei

“…Key points NLRP3 inflammasome activation is pivotal in mediating the excessive inflammatory response in ALI/ARDS. …”
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The Effect of Mobile Marketing Design on Consumer Mobile Shopping by Junhong He, Fu Li, Zhongxiang Li, Hongxiu Liu

“…The conclusions of the research showed that interface quality of mobile sales terminal and integrity of mobile sales terminal had significant positive impacts on consumption emotion; sales promotion in mobile sales terminal had a significant positive impacts on continual intention of mobile shopping; consumption emotion had a significant positive effect on continual intention of consumers in mobile shopping; consumption emotion played a significant mediating role in the relationship between interface quality of mobile sales terminal and continual intention of mobile shopping and between integrity of mobile sales terminal and continual intention of mobile shopping. …”
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Interpretative phenomenological analysis of guidance advocates’ online counseling experiences by Amabel Tangco-Siason, Rex S. Paulino

“…The mechanisms that promote a reciprocal, technology-mediated kind of communication are central to this emerging structure.…”
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Free-caged rearing modes regulate chicken intestinal metabolism by influencing gut microbial homeostasis by Tao Li, Peng Wang, Zhuo Zhi, Tong Guo, Jie Zhou, Huiya Zhang, Chang Cao, Yingjie Cai, Yuxiao Li, Jianqin Zhang

“…This study offers new insights into how rearing modes influence gut microbiota and metabolites, shedding light on the study of rearing mode-mediated muscle development and fat deposition.…”
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Meaning in life from a cultural perspective: the role of cultural identity, perceived social support, and resilience among Chinese college students by Song Zhou, Lixia Jiang, Wenjie Li, Man Leng

“…The results indicate that cultural identity has a significant positive effect on college students’ meaning in life, while perceived social support and resilience play a chain mediating role in both. In addition, the network analysis was employed to further identify the core items of each variable in the model. …”
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Temperature Depended Role of Shigella flexneri Invasion Plasmid on the Interaction with Acanthamoeba castellanii by Amir Saeed, David Johansson, Gunnar Sandström, Hadi Abd

“…The outcome of the interaction was depended on the temperature since the growth of A. castellanii was inhibited at 30∘C, and A. castellanii was killed by invasion plasmid mediated necrosis at 37∘C.…”
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Functionally-informed fine-mapping identifies genetic variants linking increased CHD1L expression and HIV restriction in monocytes by Riley H. Tough, Paul J. McLaren, The International Collaboration for the Genomics of HIV

“…Taken together, this work characterizes genetically regulated CHD1L expression and further expands our knowledge of CHD1L-mediated HIV restriction in monocytes.…”
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A Rare but Fascinating Disorder: Case Collection of Patients with Schnitzler Syndrome by Maaman Bashir, Brittany Bettendorf, Richard Hariman

“…Interleukin-1 is considered the key mediator, and interleukin-1 inhibitors are considered first line treatment. …”
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In Vitro Effects of Some Botanicals with Anti-Inflammatory and Antitoxic Activity by Gianandrea Guidetti, Alessandro Di Cerbo, Angela Giovazzino, Valentina Rubino, Anna Teresa Palatucci, Sara Centenaro, Elena Fraccaroli, Laura Cortese, Maria Grazia Bonomo, Giuseppina Ruggiero, Sergio Canello, Giuseppe Terrazzano

“…Tetracyclines, in particular oxytetracycline (OTC), appear to correlate with the emergence of immune-mediated diseases. Accumulation of OTC, the elective drug for gastrointestinal and respiratory infectious disease treatment in broiler chickens, was reported in chicken edible tissues and could represent a potential risk for pets and humans that could assume this antibiotic as residue in meat or in meat-derived byproducts. …”
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Cultured Human Airway Epithelial Cells (Calu-3): A Model of Human Respiratory Function, Structure, and Inflammatory Responses by Yan Zhu, Aaron Chidekel, Thomas H. Shaffer

“…To model human respiratory conditions and treatment modalities, monolayers are placed in an environmental chamber, and exposed to specific levels of oxygen or other therapeutic modalities such as positive pressure and medications to assess the effect of interventions on inflammatory mediators, immunologic proteins, and antibacterial outcomes. …”
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The History of Popularization of Science in France by M. D. Romanova

“…The article discusses the process of popularization of science in France in terms of bilateral cooperation between scientists and the media. Mediator in the relationship of the two parties is a science journalist. …”
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Learn from international recommendations and experiences of countries that have successfully implemented monoclonal antibody prophylaxis for prevention of RSV infection by Sara Manti, Eugenio Baraldi

“…Abstract Respiratory syncytial virus (RSV)-mediated bronchiolitis causes a significant global health burden. …”
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Male Remating Success and the Frequency of Copulatory Plugs in the Green Lynx Spider Peucetia viridans (Araneae, Oxyopidae) by Martin G. Ramirez, Angelik C. Achekian, Catherine R. Coverley, Rachel M. Pierce, Sarah S. Eiman, Melissa M. Wetkowski

“…Enhanced prey access mediated by increased water availability may be why females at two sites were in relatively better condition. …”
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High-density lipoprotein nanoparticles spontaneously target to damaged renal tubules and alleviate renal fibrosis by remodeling the fibrotic niches by Shanshan He, Xiaoyang Li, Yuanyuan He, Ling Guo, Yunzhou Dong, Leilei Wang, Lan Yang, Lin Li, Shiyun Huang, Jiali Fu, Qing Lin, Zhirong Zhang, Ling Zhang

“…In this study, we discover that biomimetic high-density lipoprotein (bHDL) lipid nanoparticles possess excellent targeting ability to injured tubular epithelial cells by kidney injury molecule-1(KIM-1) mediated internalization. Thus, we co-load anti-inflammatory drug triptolide (TP) and anti-fibrotic drug nintedanib (BIBF) on bHDL nanoparticles to treat CKD. …”
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Decitabine Increases the Transcription of <i>RIG-I</i> Gene to Suppress the Replication of Feline Calicivirus and Canine Influenza Virus by Shaotang Ye, Zhen Wang, Aolei Chen, Ying Chen, Gaoming Lou, Qingmei Xie, Gang Lu, Shoujun Li

“…In summary, this study unveils the antiviral role of decitabine against FCV and CIV and provides evidence and novel insights into the demethylation drug-mediated antiviral effect for animal RNA viruses.…”
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The role of IELTS teacher’s metapathy in IELTS candidates’ overall band score, language learning orientation, and active/passive motivation by Hamed Ghaemi, Robert Kirkpatrick

“…Additionally, the frequency of teacher-student interaction was found to mediate the relationship between teacher metapathy and students’ motivation levels. …”
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Social-emotional competence in early adolescence: the role of prosocial behaviour and peer acceptance by Rozi Sastra Purna, Liliyana Sari, Fitri Angraini, Fauziah Afrilda

“…Further analysis also revealed that peer acceptance partially mediated the relationships between prosocial behaviour and social-emotional competence. …”
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Incomplete remyelination via therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function by Gustavo Della-Flora Nunes, Lindsay A. Osso, Johana A. Haynes, Lauren Conant, Michael A. Thornton, Michael E. Stockton, Katherine A. Brassell, Amanda Morris, Yessenia I. Mancha Corchado, John A. Gaynes, Anthony R. Chavez, Michaelanne B. Woerner, Deidre A. MacKenna, Aryan Alavi, Anne Danks, Alon Poleg-Polsky, Rohan Gandhi, Jeffrey A. Vivian, Daniel J. Denman, Ethan G. Hughes

“…Here, we use in vivo two-photon microscopy and electrophysiology to study the dynamics of endogenous and therapeutic-induced cortical remyelination and functional recovery after cuprizone-mediated demyelination in mice. We focus on the visual pathway, which is uniquely positioned to provide insights into structure-function relationships during de/remyelination. …”
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Research Progress on the Digestion Characteristics and Influencing Factors of Whole Grain Brown Rice by WANG Dan, ZHAI Xiao-tong, ZHANG Na, WU Na-na, TAN Bin

“…Additionally, these health effects also result from alterations in the digestion and absorption efficiency of dietary nutrients like carbohydrates and proteins, mediated by these bioactive compounds. The digestion process of food is a key link related to the aforementioned effects. …”
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Pulmonary Histoplasmosis in a Referral Hospital in Mexico City by Alejandro Hernández Solís, Javier Araiza Santibáñez, Jazmín Guadalupe Tejeda Olán, Andrea Quintana Martínez, Alejandro Hernández de la Torriente, Rocio de la Torriente Mata

“…The signs and symptoms of the disease are mediated by the immune status of the host. The clinical picture is often confused with systemic diseases. …”
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