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6861
Characterizing the Contaminant-Adhesion of a Dibenzofuran Degrader <i>Rhodococcus</i> sp.
Published 2025-01-01“…The results showed that the adhesion between strain p52 and DF is mediated by extracellular polymeric substances (EPSs). …”
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6862
Adipokines as Drug Targets in Diabetes and Underlying Disturbances
Published 2015-01-01“…We also survey current attempts to exploit adipokines for clinical applications, which hold potential as novel approaches to drug development in several immune-mediated diseases.…”
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6863
Investigating Non-steroidal Anti-Inflammatory Drugs as Potential Cancer Adjuncts: A Novel Approach to Cancer Therapy
Published 2025-02-01“…Results: NSAIDs demonstrate significant anticancer effects by targeting inflammation-mediated pathways. They exhibit promising outcomes in reducing metastasis, promoting apoptosis, and inhibiting tumor invasion and progression. …”
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6864
Integrating TRPV1 Receptor Function with Capsaicin Psychophysics
Published 2016-01-01“…TRPV1 receptors function as homotetramers that also respond to heat, proinflammatory substances, lipoxygenase products, resiniferatoxin, endocannabinoids, protons, and peptide toxins. Kinase-mediated phosphorylation of TRPV1 leads to increased sensitivity to both chemical and thermal stimuli. …”
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6865
Circuitry and Synaptic Dysfunction in Alzheimer’s Disease: A New Tau Hypothesis
Published 2020-01-01“…For more than five decades, the field of Alzheimer’s disease (AD) has focused on two main hypotheses positing amyloid-beta (Aβ) and Tau phosphorylation (pTau) as key pathogenic mediators. In line with these canonical hypotheses, several groups around the world have shown that the synaptotoxicity in AD depends mainly on the increase in pTau levels. …”
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6866
CORPORATE SOCIAL RESPONSIBILITY AUTHENTICITY AND FIRM PERFORMANCE IN AN EMERGING MARKET
Published 2023-12-01“…This study contributes to existing knowledge by exploring the mediating roles of OID and CRE in the relationship between CSRA and FPE. …”
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6867
Early Determinants of Intergenerational Upward and Downward Educational Mobility
Published 2025-01-01“…The results showed indirect effects of teacher and parent expectations on upward and downward mobility, mediated by student achievement, after controlling for gender and conscientiousness. …”
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6868
Regulated microbe vaccines: from concept to (pre-clinical) reduction to practice
Published 2025-12-01“…This protection appeared to be at least in part antibody-mediated. These findings support a rational expectation that RCCVs may be developed into universal, non-seasonal vaccines against influenza and, possibly, against other rapidly evolving pathogens.…”
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6869
Interaction of Herbal Compounds with Biological Targets: A Case Study with Berberine
Published 2012-01-01“…In addition, berberine was found to interact with a mixture of biological pathways, such as Alzheimer’s disease-presenilin and -secretase pathways, angiogenesis, apoptosis signalling pathway, FAS signalling pathway, Hungtington disease, inflammation mediated by chemokine and cytokine signalling pathways, interleukin signalling pathway, and p53 pathways. …”
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6870
Hairpin in a haystack: In silico identification and characterization of plant-conserved microRNA in Rafflesiaceae
Published 2025-01-01“…Rafflesiaceae miRNA promoters are mostly inducible by ethylene that mediates stress response in the host but could be perceived by the parasites as a signal for growth. …”
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6871
Regulation of CXCR6 Expression on Adipocytes and Osteoblasts Differentiated from Human Adipose Tissue-Derived Mesenchymal Stem Cells
Published 2020-01-01“…Increased expression of CXCR6 on Ad was mediated by both receptor recycling, which was in turn regulated by secretion of CXCL16, and de novo synthesis. …”
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6872
Analysis of In Vitro Effects of Sex Steroids on Lymphocyte Responsiveness in Murrah Buffaloes (Bubalus bubalis)
Published 2012-01-01“…Present study was carried out on forty four apparently healthy Murrah buffaloes of different age groups of both sexes to investigate the effects of sex steroids on cell mediated immunity in vitro. Estrogen inhibited proliferation in mitogen-stimulated lymphocytes from prepubertal but not post pubertal buffaloes of either sex. …”
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6873
Induction of tyrosine aminotransferase in mice is inhibited by activated metabolites of ortho- aminoazotoluene
Published 2015-07-01“…Aminoazo dyes and other hepatocarcinogenic substances inhibit glucocorticoid-mediated induction of adaptive enzymes, including tyrosine aminotransferase (TAT), in mouse and rat liver. …”
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6874
Cissus quadrangularis: A comprehensive review as an emerging biomaterial for periodontal regeneration
Published 2025-01-01“…Periodontal disease is a polymicrobial host immune-mediated inflammatory disease that destroys supporting structures of the teeth. …”
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6875
The longitudinal relationships of problematic social media use, self-transcendence values and school adaptation: a two-wave study
Published 2025-01-01“…Moreover, each of them plays a mediating role in the association between the other two variables. …”
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6876
Phadiatop Infant in the Diagnosis of Atopy in Children with Allergy-Like Symptoms
Published 2009-01-01“…The results from the present study suggest that Phadiatop Infant could be recommended as a complement to the clinical information in the differential diagnosis on IgE-mediated disease in young children with allergy-like symptoms.…”
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6877
Switchable Adhesion of Hydrogels to Plant and Animal Tissues
Published 2025-02-01“…This underscores that EA is mediated by the electrophoresis of chain segments across the gel‐tissue interface.…”
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6878
FOXA3, a Negative Regulator of Nur77 Expression and Activity in Testicular Steroidogenesis
Published 2021-01-01“…In mouse primary Leydig cells, adenovirus-mediated overexpression of FOXA3 had similar effects and resulted in decreased production of testosterone. …”
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6879
Employee Performance Model Through Work Productivity: Work Professionalism and Training in PT Semen Padang
Published 2024-06-01“…Additionally, both professionalism and training serve as mediators, positively influencing employee performance due to their impact on work productivity. …”
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6880
FPIES: Reviewing the Management of Food Protein-Induced Enterocolitis Syndrome
Published 2016-01-01“…FPIES is a complex form of non-IgE mediated food allergy. More awareness and knowledge of the condition are required to prevent misdiagnosis. …”
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