BMP-9 mediates fibroproliferation in fibrodysplasia ossificans progressiva through TGF-β signaling by Chengzhu Zhao, Yoshiko Inada, Souta Motoike, Daisuke Kamiya, Kyosuke Hino, Makoto Ikeya

“…In this study, we evaluated the proliferation of MSCs obtained from FOP patient-derived induced pluripotent stem cells (FOP-iPSCs) to elucidate the mechanisms underlying flare-ups and found that bone morphogenetic protein (BMP)-9 mediated enhanced proliferation by abnormal activation of transforming growth factor (TGF)-β signaling pathway in MSCs from FOP-iPSCs. …”
Get full text

Hyperglycemia Inhibits Complement-Mediated Immunological Control of S. aureus in a Rat Model of Peritonitis by Clifford T. Mauriello, Pamela S. Hair, Reuben D. Rohn, Nicholas S. Rister, Neel K. Krishna, Kenji M. Cunnion

“…Previous work in our laboratory demonstrated that elevated glucose (>6 mM) dramatically inhibited S. aureus-initiated complement-mediated immune effectors. Here we report in vivo studies evaluating the extent to which a hyperglycemic environment alters complement-mediated control of S. aureus infection in a rat peritonitis model. …”
Get full text

Gut Microorganism-Mediated Neutralization of Mycotoxins: A Promising Approach to Combat Fungal Toxicity by Md Minarul Islam, Nasir Uddin Mahbub, Mohammad Amirul Islam

“…However, the utilization of microorganism-mediated biotransformation presents a particularly promising and actively researched avenue for addressing the challenges posed by mycotoxins and enhancing food safety protocols. …”
Get full text

Antagonistic functions of CTL1 and SUH1 mediate cell wall assembly in Arabidopsis by Nguyen Thi Thuy, Hyun‐Jung Kim, Suk‐Whan Hong

Get full text

Ascorbic Acid Augments Arsenic-Mediated Cell Death in Multiple Myeloma (MM) Cells by Jennifer M. Grad, Nizar J. Bahlis, Lawrence H. Boise

Get full text

Impact of family care on sleep quality in perimenopausal women: mediating roles of anxiety and depression by Nana Liang, Jishun Ren, Juan Zhao, Xiaohui Liu, Haixia Zheng

Subjects: Get full text

Postrecruitment Function of Yeast Med6 Protein during the Transcriptional Activation by Mediator Complex by Gwang Sik Kim, Young Chul Lee

“…Med6 protein (Med6p) is a hallmark component of evolutionarily conserved Mediator complexes, and the genuine role of Med6p in Mediator functions remains elusive. …”
Get full text

The Role of Organizational Learning in Mediating the Relationship between Business Model Design and Innovation Performance by Jia Zhang, Hui Xu, Xiangxia Xiao

“…This paper focused on exploring the role of organizational learning in mediating the relationship between business model design and innovation performance using hierarchical hybridized linear regression analysis (HHLRA). …”
Get full text

CRIP1 inhibits cutaneous melanoma progression through TFAM-mediated mitochondrial biogenesis by Jianqiang Wu, Lixia Chen, Peijun Wen

“…Our results suggest that CRIP1 inhibits the proliferation and invasive ability of cutaneous melanoma cells by suppressing TFAM-mediated mitochondrial biogenesis. Therefore, CRIP1 may be a potential therapeutic target for melanoma.…”
Get full text

Multiple Immunosuppressive Effects of CpG-c41 on Intracellular TLR-Mediated Inflammation by Wancheng Liu, Xuejiao Yang, Ning Wang, Shijun Fan, Yuanfeng Zhu, Xinchuan Zheng, Yan Li

“…Mediators of Inflammation…”
Get full text

The effect of academic enthusiasm on academic hope through the mediating role of academic optimism in students by Gholamhasan Panahi, Tayebeh Ordouni, Sajad Kazemi

“…The aim of the study was to determine the effect of academic enthusiasm on academic hope with the mediating role of academic optimism in students. This research was applied in terms of purpose and descriptive in terms of correlation type using the method of structural equations. …”
Get full text

Kinetic Profiles of Inflammatory Mediators in the Conjunctival Sac Fluid of Patients upon Photorefractive Keratectomy by Veronica Tisato, Paolo Perri, Erika Rimondi, Elisabetta Melloni, Giuseppe Lamberti, Daniela Milani, Paola Secchiero, Giorgio Zauli

“…Mediators of Inflammation…”
Get full text

Hypocrellin A-mediated photodynamic antibacterial activity against Cutibacterium acnes: An in vitro study by Muqiu Zhang, Xinyao Liu, Xin Ran, Runyan Gao, Jitong Sun, Kaiwen Zhuang, Zimeng You, Zhi Zhang, Yuping Ran

“…This study aimed to evaluate the antibacterial ability of hypocrellin mediated PDT against Cutibacterium acnes. Using modified broth dilution method and morphological observation, the antibacterial effect was tested under a series of experimental conditions. …”
Get full text

Vietnamese religiosity, premarital sexual permissiveness, and abortion attitudes: the mediating role of filial piety by Phuoc-Thien Nguyen, Vu Hoang Anh Nguyen, Tuan-Khai Truong, Tri-Bao Nguyen, Ky Luu, Vy Truc Le, Ngoc-Han Nguyen-Thi, Yen-Trang Chu-Nguyen, Lan Thi Nguyen, Vinh-Long Tran-Chi

“…Filial piety played a mediating role in the relationship between IR and AAS. …”
Get full text

The Effect of Professional Attitude on Motivation with a Strategic Management Perspective: The Mediating Role of Trust by Muhammed Ali Yetgin

“…As a result of the findings, it was understood that professional attitude did not have a statistically significant mediating effect on trust, and trust did not have a statistically significant mediating effect on motivation. …”
Get full text

The effect of leadership styles on employee’s performance in Ethiopian sports organizations with mediating and moderating roles by Yifan Liu, Abyot Abdela Ali, Jiawen Pan, Yi Xiao

“…It specifically examined the mediating effects of job satisfaction and the moderating impact of education level. …”
Get full text

The impact of future time perspective on academic achievement: Mediating roles of academic burnout and engagement. by Shuai Hong

“…Notably, the mediating effect of academic burnout was found to be more significant than that of academic engagement. …”
Get full text

Hemoglobin mediates the link between the ‘weekend warrior’ physical activity pattern and diabetic retinopathy by Baohua Li, Bobiao Ning, Xinyue Hou, Yipeng Shi, Zefeng Kang

“…Moreover, compared to the RA and insufficiently active PA patterns, WW did not show a significant association with DR, whereas the inactive PA pattern (OR = 1.355, 95% CI = 1.054–1.742, P = 0.018) was a risk factor. Mediation analysis revealed a significant partial mediation effect of Hb level on the association between PA pattern and DR risk, with a mediation ratio of 5.95%. …”
Get full text

Role of Zinc Signaling in the Regulation of Mast Cell-, Basophil-, and T Cell-Mediated Allergic Responses by Keigo Nishida, Ryota Uchida

“…In this review, we discuss the impact of zinc signaling focusing particularly on mast cell-, basophil-, and T cell-mediated inflammatory and allergic responses. We also describe zinc signaling dysregulation as a leading health problem in inflammatory disease and allergy.…”
Get full text

Constructing Functional Ionic Membrane Surface by Electrochemically Mediated Atom Transfer Radical Polymerization by Fen Ran, Dan Li, Jiayu Wu

Get full text