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When cell teamwork turns toxic
Published 2025-04-01“…In pulmonary hypertension, a combination of metabolic and mechanical dysfunction leads to irreversible vascular damage.…”
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ACE inhibitors and myocardial remodeling in patients with arterial hypertension and atrial fibrillation
Published 2007-10-01“…After sinus rhythm restoration, mechanical dysfunction of left atrium was observed in 95, 8 % of the participants. …”
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Atrial Cardiomyopathy: From Diagnosis to Treatment
Published 2025-01-01“…Furthermore, persistent AF can exacerbate structural and electrical remodeling, as well as mechanical dysfunction of the atria, creating a vicious cycle. …”
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Bifurcation in the healing or fibrotic response in a network model of fibrosis: role of the initial injury structure
Published 2025-07-01“…Previous evidence suggests that percolation behavior, where increasing local stiffness facilitates the emergence of stiff regions that span the tissue, underlies the stiffening of the ECM and drives the irreversible mechanical dysfunction. However, it is not fully understood how percolation emerges from the complex interactions between cells and the ECM.MethodsIn this study, we investigated a previously published agent-based spring network model of PF that exhibited bifurcation behavior between healing and fully developed fibrosis as network members were gradually stiffened. …”
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Mechanical properties of extrinsic foot muscles, Achilles tendon, and plantar fascia in patients with a history of diabetic foot ulcers
Published 2025-05-01“…The findings emphasize the importance of early biomechanical assessment and targeted rehabilitation strategies, such as neuromuscular training, load redistribution, Achilles tendon stretching and custom orthotic interventions to mitigate mechanical dysfunction in diabetic foot patients. Clinical trial number Not applicable.…”
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Application of Acoustic Cardiography in Assessment of Cardiac Function in Horses with Atrial Fibrillation Before and After Cardioversion
Published 2025-07-01“…Left atrial mechanical dysfunction is common in horses following the treatment of atrial fibrillation (AF). …”
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From stress to sight: The role of mechanical forces in the retinal diseases
Published 2025-08-01“…The integration of mechanistic insights with biomechanical assessment techniques offers transformative potential for diagnosing mechanical dysfunction and developing mechanotargeted therapies.…”
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Primary Effect of SERCA2a Gene Transfer on Conduction Reserve in Chronic Myocardial Infarction
Published 2018-09-01“…Methods and Results Pigs developed mechanical dysfunction 1 month after anterior MI, at which point they received intracoronary adeno‐associated virus serotype 1.SERCA2a (MI+SERCA2a) or saline (MI) and were maintained for 2 months. …”
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Atraumatic Bilateral Patellar Tendon Rupture: A Case Report
Published 2025-03-01“…Introduction: Bilateral patellar tendon rupture is an uncommon reason for extensor mechanism dysfunction. Various predisposing factors, including systemic diseases and the use of steroids or antibiotics, can elevate the risk. …”
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CARDIAC VALVE PROSTHESIS «MEDENG-2»: 10 YEARS EXPERIENCE OF CLINICAL APPLICATION Vavilov P.A.
Published 2010-06-01“…-years (86,4%) for AVR, 2530 (82,4%) for MVR and 836 (82,9%) for DVR. Mechanical dysfunctions of artificial valves were not. Freedom from a thrombosis, endocarditis and reoperations at AVR has made 98,7; 97,6; 97,1% accordingly. …”
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Injury Patterns in Fencing Athletes – A Retrospective Review
Published 2024-09-01“… # Conclusion The majority of injuries in these fencing athletes affected the lower extremity, most commonly the knee. Extensor mechanism dysfunction, primarily patellofemoral pain, was the most common diagnosis. …”
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Immediate Effects of Uphill Treadmill Walking Exercise on Ankle Dorsiflexion Range of Motion and Torque in Patients With Limited Ankle Dorsiflexion
Published 2024-12-01“…Background: Limited ankle dorsiflexion (DF) range of motion (ROM) is associated with mechanical dysfunctions and chronic ankle instability. Uphill treadmill walking exercise (UTWE) has the potential to improve ankle mobility and function. …”
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