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41901
Effect of optimizing the nursing process of green channel on time course of intravenous thrombolysis for acute ischemic stroke (优化绿色通道护理流程对急诊缺血性脑卒中静脉溶栓时间节点的影响)...
Published 2022-08-01“…The time between admission to CT scanning, time between admission to signing the informed consent, door-to-needle time (DNT) and proportion of patients with DNT≤35 min were measured and compared between groups. Results Shorter time between admission to CT scanning, time between admission to signing the informed consent and door-to-needle time were reported in the observation group than those in the control group(P<0. 0). …”
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41902
Effects of flame retardant tributyl phosphate on early development of zebrafish
Published 2024-12-01“…The whole-body triiodothyronine (T3) and tetraiodothyronine (T4) levels of juvenile fish were measured by enzyme immunoassay at the end of the infection, and the expression levels of hypothalamic-pituitary-thyroid axis (HPT) and neurodevelopmental-related genes were detected by quantitative real-time PCR (q-PCR). …”
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41903
Examining the impact of a community-based exercise intervention on cardiorespiratory fitness, cardiovascular health, strength, flexibility and physical activity among adults living...
Published 2021-01-01“…<h4>Methods</h4>We conducted a longitudinal intervention study with community-dwelling adults living with HIV in Toronto, Canada. We measured cardiopulmonary fitness (V̇O2peak (primary outcome), heart rate, blood pressure), strength (grip strength, vertical jump, back extension, push-ups, curl ups), flexibility (sit and reach test), and self-reported physical activity bimonthly across three phases. …”
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41904
Evaluating academic detailing as an antibiotic stewardship intervention in primary healthcare settings in Croatia
Published 2024-12-01“…Therefore aim of this study was to evaluate impact of AD intervention as an antimicrobial stewardship measure on antibiotic prescribing for acute respiratory tract infections in primary setting in Croatia which is located in southeastern Europe. …”
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41905
Risk factors for gastric cancer and related serological levels in Fujian, China: hospital-based case–control study
Published 2020-09-01“…Objective To explore the relationships between gastric cancer and serum pepsinogen I (PG I), PG II, PG I/II ratio, gastrin 17 (G-17) and Helicobacter pylori infection, and to investigate dietary and lifestyle risk factors for gastric cancer in Fujian Province, China.Design A hospital-based, 1:1 matched case–control study.Setting Patients with newly diagnosed gastric cancer were recruited from the Fujian Provincial Hospital and the No. 900 Hospital of the Joint Support Force of the Chinese People’s Liberation Army between July 2014 and December 2016.Participants A total of 180 pairs of patients with gastric cancer and control subjects were recruited in the study, including 134 (74.4%) male pairs and 46 (25.6%) female pairs.Investigation and analysis measures Serological indicators were tested with ELISA kits. …”
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41906
Optimising compensatory growth in pastoral beef production systems: insights into feed efficiency, body composition, carcass characteristics and meat quality attributes
Published 2025-02-01“…Two extra slaughters were done with other representative steers on day 0 and day 97, to provide baseline parameters for carcass and non-carcass measurements. During the backgrounding period, optimal steers gained more than suboptimal (P < 0.01), resulting in higher BW and hot carcass weight (HCW; P < 0.01). …”
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41907
Cardiovascular risk associated with glucagon-like peptide-1 receptor agonists versus other conventional glucose-lowering drugs in patients with type-2 diabetes: protocol for a nati...
Published 2025-01-01“…Treatment effects on the different outcomes measured will be estimated for each GLP1-RA group, through HR and their corresponding CIs (95% CI) using Cox regressions and/or competitive risk regressions when necessary.Ethics and dissemination The study has been approved by an independent ethics committee (Comité éthique et scientifique pour les recherches, les études et les évaluations dans le domaine de la santé, Paris, France; reference: 8699786, dated 2 June 2022) and has been registered with the French National Data Protection Commission (Commission Nationale de l'Informatique et des Libertés, Paris, France; reference: 922161, dated 26 June 2022). …”
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41908
A comprehensive, population level evaluation of previously reported drug triggers of pemphigus highlights immunomodulatory capacity as a common characteristic
Published 2025-01-01“…Despite anecdotal reports linking multiple drugs to PV, corroborating evidence from large datasets is missing.ObjectiveTo examine the extent to which previously reported associations between a comprehensive list of 36 drugs implicated in PV pathogenesis could be replicated using population-level pharmacovigilance data.DesignSeries of observational, retrospective, case-control, pharmacovigilance analyses (one analysis/drug, 36 total).SettingPopulation based.ParticipantsIndividuals who submitted a report of a drug-related adverse event to the FDA from Q4 of 2003 to Q2 of 2023.ExposureCases were identified by the presence of adverse events described by the MedDRA preferred term “pemphigus” (10034280) and then sorted based on exposure to each of the drugs of interest.Main outcomes and measuresReporting Odds Ratios (RORs) quantifying the association between a given drug exposure and reports of pemphigus adverse events.ResultsThe analyses revealed statistically significant associations between reports of pemphigus and exposure to 11/36 previously reported drugs, two of which had particularly high RORs (>200) [gold sodium thiomalate (ROR, 266.0; 95% CI, 202.6-349.3) and hydroxychloroquine (ROR, 282.6; 95% CI, 261.0-306.1)], three had very strong RORs (14-45) [penicillamine (ROR, 30.5; 95% CI, 11.4-81.7), piroxicam (ROR, 14.8; 95% CI, 8.2-26.7), and imiquimod (ROR, 42.3; 95% CI, 26.2-68.3)], and six had modestly strong RORs (2-5) [rifampin (ROR, 2.8; 95% CI, 1.4-5.6), hydrochlorothiazide (ROR, 1.6; 95% CI, 1.2-2.1), irbesartan (ROR, 2.7; 95% CI, 1.6-4.4), lisinopril (ROR, 5.3; 95% CI, 4.5-6.2), nivolumab (ROR, 2.7; 95% CI, 1.8-4.1), and nifedipine (ROR, 3.0; 95% CI, 1.9-5.0)]. …”
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41909
Impact of iron chelation with deferasirox on telomere length and oxidative stress in hemodialysis patients: A randomized study
Published 2025-01-01“…Telomere length was measured using real-time PCR. Serum ferritin levels and oxidation markers were evaluated. …”
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41910
Clinical observation on effect of endurance exercise for elderly patients with maintenance hemodialysis (耐力运动在老年维持性血液透析患者中的应用效果观察)
Published 2022-07-01“…The 6-Minute Waling Test (6MWT), Berg Balance Scale and hand grip strength measuring were used to assess the patients’ motor function. …”
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41911
Do doctors in dispensing practices with a financial conflict of interest prescribe more expensive drugs? A cross-sectional analysis of English primary care prescribing data
Published 2019-02-01“…Logistic regression was used to calculate ORs for prescribing high-cost options in dispensing practices, adjusting for Index of Multiple Deprivation score, practice list size and the number of doctors at each practice.Setting English primary care.Participants All general practices in England.Main outcome measures Mean cost per dose was calculated separately for dispensing and non-dispensing practices. …”
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41912
Reduced Serum Glucagon Like Peptide-1 In Children with Osteoporosis of Chronic Liver Diseases: A Single Center Trial
Published 2025-01-01“…Subjects and Methods: This cross-sectional study included 60 children with CLD as a study group and 60 healthy participants as a control group. GLP- 1 was measured using ELISA technique and compared between groups. …”
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41913
Performance of a hybrid capture-based target enrichment next-generation sequencing for the identification of respiratory pathogens and resistance-associated genes in patients with...
Published 2025-01-01“…Unlike conventional phenotypic approach, novel measures using molecular interrogation appear promising. …”
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41914
Complex program for the prevention of the development and progression of refractive errors in school year children
Published 2021-09-01“…Visual acuity, cycloplegic refraction, reserves of relative accommodation, and axial length (measured by ultrasound) were indicators of visual impairments in children during monitoring. …”
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41915
Modification and analysis of context-specific genome-scale metabolic models: methane-utilizing microbial chassis as a case study
Published 2025-01-01“…The CS-GSM predictions agreed with the experimental measurements under the assumption that the Fae1-2 is a part of the tetrahydrofolate-linked pathway. …”
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41916
Improved performance of botia fish Chromobotia macracanthus with the utilization of blood clam shell in the recirculation system
Published 2020-11-01“…Every 15 days, weight and length of fish were measured (for 60 days). The results of physical (temperature) and chemical (pH, dissolved oxygen, ammonia dan nitrite) water quality in the recirculation system using the blood clam filter showed good conditions for botia fish. …”
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41917
Effect of Bian-stone hot ironing-massage and Chinese herbal medicine penetration combined with auricular acupoint sticking and pressing on relief of incomplete intestinal obstructi...
Published 2022-12-01“…The time to relief of abdominal pain, abdominal distension and difficult defecation were observed, and the treatment efficacy was measured and compared between two groups. Results The time to relief of abdominal pain, abdominal distension, nausea and vomiting and difficult defecation in the treatment group was shorter than that in the control group (P<0. 01). …”
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41918
Determining nutritional indices of Dori bleak, Alburnus doriae and Brond Snout, Chondrostoma regium in Zayandehroud River, Central Iran
Published 2024-09-01“…The purpose of this study was to determine the type of diet and feeding habits by analyzing the gut contents of A. doriae and C. regium and measuring some nutritional indicators. The findings of this study could be used to protect biodiversity and provide a better understanding of the structure of food web in Zayandehroud River. …”
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41919
The role of the behavioral immune system in the expression of short and long-term orientation in young Chilean men during the COVID-19 pandemic
Published 2025-02-01“…In addition, we carry out analyses with a reduced sample to re-test our predictions based on the perception of contagion risk (measured by a survey from OMS). Conclusion We find changes are maintained at the level of sociosexual desire and sexual behavior but mainly in those individuals with a greater perception of the risk of contagion. …”
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41920
L’aqueduc du Gier : nouvelles données sur le pont-siphon de Beaunant à Sainte-Foy-lès-Lyon (Métropole de Lyon)
Published 2023-12-01“…Nonetheless, these two trenches revealed a base consisting of three courses of large limestone blocks measuring up to 2 m in height.The opus quadratum foundations of these two piers were built using limestone blocks originating from regional quarries. …”
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