Beta 3 adrenoreceptors protect from hypertrophic remodelling through AMP‐activated protein kinase and autophagy by Emilie Dubois‐Deruy, Roselle Gelinas, Christophe Beauloye, Hrag Esfahani, Lauriane Y.M. Michel, Chantal Dessy, Luc Bertrand, Jean‐Luc Balligand

“…Concomitant with hypertrophy, autophagy was decreased by PE, as measured by microtubule‐associated protein 1 light chain 3 (LC3)‐II/LC3‐I ratio (/2.6, P = 0.0010) and p62 abundance (×3, P = 0.0016) in NRVM or by TAC in WT mice (LC3‐II/LC3‐I ratio: /5.4, P = 0.0159), but preserved in human β3‐AR expressing cells and mice, together with reduced hypertrophy. …”
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Gegen Qinlian Decoction Attenuates Colitis-Associated Colorectal Cancer via Suppressing TLR4 Signaling Pathway Based on Network Pharmacology and In Vivo/In Vitro Experimental Valid... by Yaoyao Xu, Qiaoyan Cai, Chunyu Zhao, Weixiang Zhang, Xinting Xu, Haowei Lin, Yuxing Lin, Daxin Chen, Shan Lin, Peizhi Jia, Meiling Wang, Ling Zhang, Wei Lin

“…Enzyme-linked immunosorbent assay measured IL-1β, IL-6, and TNF-α levels. Immunofluorescence (IF) staining visualized NF-κB and IRF3 translocation. …”
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Comparative Analysis of Tillage Indices and Machine Learning Algorithms for Maize Residue Cover Prediction by Jian Li, Kewen Shao, Jia Du, Kaishan Song, Weilin Yu, Zhengwei Liang, Weijian Zhang, Jie Qin, Kaizeng Zhuo, Cangming Zhang, Yu Han, Yiwei Zhang, Bingrun Sui

“…Herein, seven tillage indices derived from Sentinel-2 satellite imagery were analyzed alongside measured MRC data to assess their correlation with MRC. …”
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LINC01089 governs the miR-1287-5p/HSPA4 axis to negatively regulate osteogenic differentiation of mesenchymal stem cells by Hao Zou, Fei Hu, Xin Wu, Bin Xu, Guifeng Shang, Dong An, Dehao Qin, Xiaolei Zhang, Aofei Yang

“…The osteogenic differentiation of MSCs was assessed through alkaline phosphatase (ALP) activity, alizarin red S (ARS) staining, and by measuring the levels of osteogenic gene marker expressions using commercial kits and RT-qPCR analysis. …”
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Short-term abstinence from alcohol and changes in cardiovascular risk factors, liver function tests and cancer-related growth factors: a prospective observational study by Gautam Mehta, Rajiv Jalan, Matteo Rosselli, James Maurice, Stewart Macdonald, Alexandra Cronberg, Tanya Khera-Butler, Colin Sumpter, Safa Al-Khatib, Anjly Jain, Christos Charalambous, Amir Gander, Cynthia Ju, Talay Hakan, Roy Sherwood, Devaki Nair, Kevin P Moore

“…Exclusion criteria were known liver disease or alcohol dependence.Primary and secondary outcome measures The primary outcome was change in insulin resistance (homeostatic model assessment (HOMA) score). …”
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Vaccarin suppresses diabetic nephropathy through <?A3B2 pi6?>inhibiting the EGFR/ERK1/2 signaling pathway by Zhu Xuexue, Meng Xinyu, Du Xinyao, Zhao Chenyang, Ma Xinyu, Wen Yuanyuan, Zhang Shijie, Hou Bao, Cai Weiwei, Du Bin, Han Zhijun, Xu Fei, Qiu Liying, Sun Haijian

“…The levels of malondialdehyde (MDA) and reactive oxygen species (ROS), as well as the content of glutathione peroxidase (GSH-Px), are measured. The protein expressions of collagen I, TGF-β1, α-SMA, E-cadherin, Nrf2, catalase, SOD3, SOD2, SOD1, p-ERK, p-EGFR (Y845), p-EGFR (Y1173), p-NFκB P65, t-ERK, t-EGFR and t-NFκB P65 are detected by western blot analysis. …”
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Personality and help-seeking for psychological distress: a systematic review and meta-analysis by Anna Szücs, Anna Szücs, Anna Szücs, Rachel Hui Xin Lam, Wymann Shao Wen Tang, Lifan Zhou, Monica Lazarus, Andrea B. Maier, Andrea B. Maier, Andrea B. Maier, Jose M. Valderas, Jose M. Valderas, Jose M. Valderas

“…However, findings regarding associations of personality traits with help-seeking have been inconsistent.MethodsThis systematic review and meta-analysis focused on English-language research studies on the association of personality (encompassing personality disorders, Five Factor –Big Five– dimensions, and other measures of personality) with depression, anxiety, or unspecified psychological distress in adults aged 18 years and older. …”
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Knowledge, attitude, and perception of Pakistani populations toward monkeypox: a cross-section study by Humayun Yousaf, Abdul Qadeer, Muhammad Sohail, Maqbool Khan, Muhammad Farooq, Zakir Khan, Dalia Fouad, Yu-Chia Liu, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen

“…The public’s adherence to preventative measures is influenced by their understanding of the infectious monkeypox virus (Mpox), attitude toward it, and perceptions of it. …”
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Maternal Satisfaction towards Childhood Immunization Service and Its Associated Factors in Wadla District, North Wollo, Ethiopia, 2019 by Fisha Alebel GebreEyesus, Nega Tezera Assimamaw, Netsanet Tsegaye GebereEgziabher, Bisrat Zeleke Shiferaw

“…Maternal satisfaction is considered one of the most frequently used indicators to measure the quality and efficiency of childhood immunization service. …”
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Characteristics and quality of biofloc in vannamei shrimp culture with different carbon sources by Muhammad Faris Allam, Julie Ekasari, Ichsan Achmad Fauzi, Wiyoto Wiyoto

“…The experimental tests were the TAN (total ammonia nitrogen) reduction test which was carried out for 16 hours and the shrimp rearing test which was carried out for 30 days. Parameters measured to determine the characteristics of biofloc in shrimp rearing test were bifloc volume, biofloc particle size, biofloc nutrient composition, and water quality. …”
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HHO–LSSVM prediction model of blast casting muck pile morphology based on Gaussian distribution by Ning MA, Li MA, Yinda LI, Tianxiang LI, Sen YANG, Fuming LIU, You ZHOU, Xiaomin WANG, Qifeng ZHANG, Mengbo LI

“…In order to improve the accuracy of predicting the shape of blast casting muck piles in surface coal mines, further optimize the design of blast casting, and reduce the cost of blast casting stripping, based on the measured data of blast casting in the Heidaigou surface coal mine, an example analysis was conducted. …”
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Rapid inference of antibiotic susceptibility phenotype of uropathogens using metagenomic sequencing with neighbor typing by Amanda C. Carroll, Leanne Mortimer, Hiren Ghosh, Sandra Reuter, Hajo Grundmann, Karel Brinda, William P. Hanage, Angel Li, Aimee Paterson, Andrew Purssell, Ashley Rooney, Noelle R. Yee, Bryan Coburn, Shola Able-Thomas, Martin Antonio, Allison McGeer, Derek R. MacFadden

“…The use of narrow-spectrum agents is desirable as an antibiotic stewardship measure; however, it is counterbalanced by the need for adequate therapy. …”
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Efficacy and safety of PD-1/PD-L1 inhibitors in advanced or recurrent endometrial cancer: a meta-analysis with trial sequential analysis of randomized controlled trials by Ji Ren, Jinghe Wang, Yanan Wang, Dongying Yang, Jianming Sheng, Shili Zhu, Yunli Liu, Xiaoqi Li, Wei Liu, Binbin Zhang

“…This study sought to assess the efficacy and safety of this therapeutic combination in patients with advanced or recurrent EC.MethodsWe performed an exhaustive review of randomized controlled trials (RCTs) up to September 25, 2024, examining the efficacy and safety of combining PD-1/PD-L1 inhibitors with CT versus CT alone (or plus placebo) in advanced or recurrent EC. Efficacy was measured by progression-free survival (PFS) and overall survival (OS), while safety was assessed by the incidence of any grade or grade ≥ 3 adverse events (AEs). …”
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Att lära om naturen från naturen och i naturen by Sara Planting-Bergloo, Emma Rova, Charlotte Lennartsdotter, Per Rohlin, Maria Andrée

“…For example, students need to be able to identify and name species, master a variety of methods to actually implement tasks in the field, know how work should be documented and to draw conclusions based on both measurable results and on more general ecological relationships. …”
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Effect of acupoint application of Traditional Chinese Medicine on recovery of gastrointestinal function after cesarean section (中药穴位敷贴促进剖宫产术后胃肠功能恢复的效果观察)... by PENG Rufeng (彭茹凤), LI Fengmin (黎凤民), HUANG Ling (黄翎), HUANG Huan (黄环), SU Qiumei (苏秋梅)

“…The bowel sound recovery time, time of anal exhaust and first time of defecation were recorded, and abdominal distension was measured at 24 h and 48 h after cesarean section. Results The bowel sound recovery time, time of anal exhaust and first time of defecation were shorter in the observation group than those in the control group(P＜0. 05). …”
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MiR-3664-3p through suppressing ABCG2, CYP3A4, MCL1, and MLH1 increases the sensitivity of colorectal cancer cells to irinotecan by Elham Farrokhnazar, Sahar Moghbelinejad, Reza Najafipour, Ladan Teimoori-Toolabi

“…The expression levels of the ABCG2, CYP3A4, MCL1, and MLH1 genes, along with miR-3664-3p, were initially measured in all resistant and parental cell lines using quantitative real-time PCR. …”
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Paracrine activity of Smurf1-silenced mesenchymal stem cells enhances bone regeneration and reduces bone loss in postmenopausal osteoporosis by Alberto González-González, Itziar Álvarez-Iglesias, Daniel García-Sánchez, Monica Dotta, Ricardo Reyes, Ana Alfonso-Fernández, Alfonso Bolado-Carrancio, Patricia Díaz-Rodríguez, María Isabel Pérez-Núñez, José Carlos Rodríguez-Rey, Jesús Delgado-Calle, Flor M. Pérez-Campo

“…Pro-osteogenic potential was assessed by measuring in vitro mineralization in human and rat MSCs cultures. …”
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Application of PDCA cycle in continuous quality improvement of nursing inventory records in the operating room (PDCA循环法在手术室护理清点记录单持续质量改进中的应用)... by YIN Bei (尹蓓), WANG Yaling (王雅玲), QIU Murong (邱慕蓉)

“…Conclusion Application of PDCA cycle in document writing may help nurses effectively analyze and improve the detailed and important problems in clinical practice, and form a relatively complete document quality control supervision system by establishing a quality improvement team, formulating measures, and supervising with other members of the department. …”
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