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861
Application of quantitative protein mass spectrometric data in the early predictive analysis of membrane-bound target engagement by monoclonal antibodies
Published 2024-12-01“…Model-informed drug discovery advocates the use of mathematical modeling and simulation for improved efficacy in drug discovery. …”
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862
RECONSTRUCTION OF MECHANISMS REGULATING THE EXPRESSION OF THE ESCHERICHIA COLI YFIA GENE UNDER STRESS CONDITIONS
Published 2014-12-01“…The regulatory region of the Escherichia coli yfiA gene was reconstructed by using the SiteCon web resource and mathematical modeling, and its expression complexity under oxidative stress was assessed. …”
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863
Solution of Extraordinary Differential Equations with Physical Reasoning by Obtaining Modal Reaction Series
Published 2010-01-01“…Mathematical modeling of many engineering and physics problem leads to extraordinary differential equations like Nonlinear, Delayed, and Fractional Order. …”
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864
Error Analysis of Some Demand Simplifications in Hydraulic Models of Water Supply Networks
Published 2013-01-01“…Mathematical modeling of water distribution networks makes use of simplifications aimed to optimize the development and use of the mathematical models involved. …”
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865
Novel, low-cost bioreactor for in vitro electrical stimulation of cardiac cells
Published 2025-02-01“…Finite element analysis and mathematical modeling were used to model the fluid dynamics and to characterize in detail the delivery of pulsatile electrical signals, providing precise control over stimulation parameters such as voltage, current, and charge.ResultsThe bioreactor developed here provides an easy-to-use, inexpensive platform for culturing hiPSC-CMs under the influence of ES and low-shear fluid flow for enhanced nutrient availability, while its “drop-in” design facilitates real-time observation of cultured cells. …”
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866
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867
Application of Image Recognition Algorithm Based on Partial Differential Equation and Wavelet Transform in the Intelligent Linkage System of Government Urban Public Management
Published 2021-01-01“…The method of mathematical modeling is used to combine the improved wavelet domain Wiener filter and the comprehensive model of partial differential equations. …”
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868
Simulation of dynamics of oscillations of manipulator using Lagrange equations of second order
Published 2022-06-01“…The article discusses the main stages of compiling a dynamic model of manipulator oscillations, based on the method of mathematical modeling, the basis of which is the circuit design of the manipulator under study. …”
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869
Evaluation of rabies control measure effectiveness in the Russian Federation
Published 2020-09-01“…The analysis of data from veterinary reports showed that the most rabies-infected regions are the Central and Volga Federal Districts. Using the mathematical modeling of the epidemic process the results of preventive measures, taken by the Veterinary Service in case of rabies in the region, were evaluated.…”
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870
Age-structured cell population model to study the influence of growth factors on cell cycle dynamics
Published 2012-11-01“…Our purpose is to analyse, through mathematical modeling, the effects of growth factors on the dynamics of the division cycle in cell populations.…”
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871
Nanocrystalline Porous Hydrogen Storage Based on Vanadium and Titanium Nitrides
Published 2017-01-01“….% of hydrogen. Data of mathematical modeling are presented highlighting the structure formation and component creation of the films during their deposition at the time of simultaneous bombardment by mixed beam of nitrogen and helium ions with energy of 30 keV. …”
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872
Analysis of a Two-Phase MHD Free Convection Generalized Water–Ethylene Glycol (50 : 50) Dusty Brinkman-Type Nanofluid Pass through Microchannel
Published 2023-01-01“…Partial differential equations (PDE) are used to present the mathematical modeling. The resultant PDEs are generalized by utilizing the Caputo–Fabrizio fractional derivative. …”
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873
Habit of elongate amphibole particles as a predictor of mesothelial carcinogenicity
Published 2025-06-01“…In addition, three validation sets (an asbestiform sample from Eastern New York and non-asbestiform samples from Quebec and Falls Village, Connecticut) were tested by Transmission Electron Microscopy (TEM) to determine dimensional distribution. Mathematical modeling was utilized to determine the classification method for amphiboles with various habits. …”
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874
Increasing survival time decreases the cost-effectiveness of using "test & treat to eliminate HIV epidemics
Published 2013-07-01“…., universal ``test & treat'') could lead to HIV elimination and would be extremely cost-effective.It is now being debated whether to use a universal ``test and treat'' approach in the ``real-world'' as a prevention strategy to control HIV epidemics.However current modeling predictions of the impact, and cost-effectiveness, of universal ``test & treat'' strategies are based on an unrealistically short survival time for treated individuals.Here we use mathematical modeling and a longer, more realistic, survival time.We model the potential impact of a universal ``test & treat'' strategy in South Africa.Our results show that increasing the length of the survival time on treatment, although beneficial to individuals, reduces the probability of eliminating HIV and decreases the cost-effectiveness of using universal ``test & treat'' strategies.Therefore our results show that individual-level benefits and public health benefits will conflict when using ``test & treat'' strategies to reduce HIV transmission.…”
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875
Numerical optimization by the PFEMCT-SIF method of the crack propagation of a linear elastic material
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876
Ozone-Catalytic Treatment of Automotive Exhaust
Published 2024-10-01“…The results of the mathematical modeling were confirmed by testing this device for purifying exhaust gases of a YaMZ-238M2 engine. …”
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877
About the modeling of light beam self-focusing in plasma at the irradiation of the target by power UV laser
Published 2021-03-01“…The interest in the experimental and mathematical modelling results is related to the laser thermonuclear fusion (LTF) research. …”
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878
Removal of Zinc from Aqueous Solution by Optimized Oil Palm Empty Fruit Bunches Biochar as Low Cost Adsorbent
Published 2017-01-01“…The impact of pyrolysis conditions, namely, highest treatment temperature (HTT), heating rate (HR), and residence time (RT) on biochar yield and adsorption capacity towards zinc, was investigated. Mathematical modeling and optimization of independent variables were performed employing response surface methodology (RSM). …”
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879
Inference of a three-gene network underpinning epidermal stem cell development in Caenorhabditis elegans
Published 2025-02-01“…Here, we integrate experimental data, mathematical modeling, and statistical inference to investigate this network, focusing on three core transcription factors (TFs), namely ELT-1, EGL-18, and CEH-16. …”
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880
Problematic Issues of Calculating the Size of Damage from the Use of Land Plots for Other Purposes within the Practice of Law Enforcement Agencies
Published 2021-03-01“…The foundations of the research methodology constitute: comparative and legal method, which assisted to study the requirements of EU and Ukrainian legislative acts; the method of systematic analysis, which allowed to reveal the legal mechanisms for calculating the amount of damage caused to the state and territorial communities from the use of land plots for other purposes; method of mathematical modeling, which allowed to form propositions for improving the formula of calculating the damage caused by the misuse of land plots. …”
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