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  1. 4941

    In-Situ Electrospinning Dressings Loaded with Kaempferol for Reducing MMP9 to Promote Diabetic Ulcer Healing by Li J, Meng H, Guo W, Zhou L, Wu S, Gao G, Liu Q, You D, Qu W

    Published 2025-01-01
    “…Histological and immunofluorescence staining were performed to determine the status of epithelization, collagen deposition, MMP9 expression, macrophage polarization, inflammation response and angiogenesis.Results: Material science experiments have shown that the dressing has optimal fiber micromorphology and good water vapor transport properties (WVTR: 4.88 kg m− 2 24h− 1); in vivo, diabetic wound experiments have shown that the high porosity and pharmacological effects of PED4 can mutually promote the rapid healing of diabetic wounds (healed 95.9% on day 15), facilitate the transformation of macrophages from M1-type to M2-type and regulate the expression of MMP9.Conclusion: Portable electrospinning dressings equipped with kaempferol not only better fit irregular wounds, but also promote wound healing through MMP9 and macrophage polarization. …”
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    Strengthening effect of particle gradation on the mechanical properties of sand powder 3D printed rock analog by Zhe Zhang, Lishuai Jiang, Atsushi Sainoki, Xiaohan Peng, Chunang Li, Qingjia Niu, Xinzhe Wang, Mingwei Gang

    Published 2025-03-01
    “…This study significantly enhances the strength and elastic modulus of SP-3DP rock-like specimens, broadening the application scope of SP-3D printing technology in rock mechanics and materials science, and providing a foundation for more accurate simulation of rock behavior under complex geological conditions.…”
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