-
801
Simultaneous Determination of Five Components of Chaihu-Shugan-San in Beagle Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study after a Single Dose of Chaihu-Shuga...
Published 2020-01-01“…The purpose of our study is to develop a reliable and sensitive high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method to detect five components in beagle plasma and study their pharmacokinetic after oral administration of CHSGS in beagles. …”
Get full text
Article -
802
Thermal Decarboxylation of Betacyanins in Red Beet Betalain-Rich Extract
Published 2020-02-01“…The first tentative structures formed by decarboxylation of the main pigment present in BRE, betanin and its diastereomer, were established by means of liquid chromatography coupled to diode array detection and electrospray ionization tandem mass spectrometry (LC-DAD-ESI-MS/MS). In the extract, two new isomeric bidecarboxylated betanins were tentatively identified. …”
Get full text
Article -
803
Comparative Pharmacokinetic Studies of Four Ginsenosides in Rat Plasma by UPLC-MS/MS after Oral Administration of Panax quinquefolius-Acorus gramineus and Panax quinquefolius Extra...
Published 2019-01-01“…In the present study, we simultaneously determined the contents of four main bioactive ginsenosides (Rb1, Rb2, Rd, and Re) in rat plasma using an ultrahigh-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method. Plasma specimens were purified by using the solid-phase extraction procedure, and separation was performed on Waters ACQUITY UPLC BEH C18 (100 mm × 2.1 mm, 1.7 μm) in multiple reaction monitoring (MRM) mode and negative electrospray ionization (ESI) mode. …”
Get full text
Article -
804
A pilot exploratory study for analysis of clinical features and plasma catecholamines in blepharospasm
Published 2025-01-01“…Plasma CA levels were measured using liquid chromatography-tandem mass spectrometry. Clinical features, plasma CAs, and metabolite contents were compared between groups. …”
Get full text
Article -
805
Multidimensional library for the improved identification of per- and polyfluoroalkyl substances (PFAS)
Published 2025-01-01“…Using a platform coupling reversed-phase liquid chromatography (RPLC), electrospray ionization (ESI) or atmospheric pressure chemical ionization (APCI), drift tube ion mobility spectrometry (IMS), and mass spectrometry (MS), the retention times, collision cross section (CCS) values, and m/z ratios were determined for all analytes and assembled into an openly available multidimensional dataset. …”
Get full text
Article -
806
GC-MS Analysis, Antimicrobial and Antioxidant Activities of Extracts of the Aerial Parts of <i>Conyza sumatrensis</i>
Published 2016-05-01“…The extracts were also analysed using Gas chromatography – Mass spectrometry, and the chromatogram coupled with mass spectra of the compounds were matched with a standard library. …”
Get full text
Article -
807
Small open reading frames (sORFs): Driving big improvements in plant development and quality
Published 2025-03-01“…With the advent of sophisticated technologies such as bioinformatics, ribosome profiling, and mass spectrometry, the investigation of sORFs has experienced a transformative shift and significant expansion. …”
Get full text
Article -
808
Site-specific N-glycosylation characterization and allergenicity analysis of globulin-1 S allele from wheat
Published 2023-09-01“…Moreover, one N-glycosylation site and 6 kinds of N-glycans were identified by mass spectrometry, including 3 high mannose types and 3 complex types. …”
Get full text
Article -
809
Understanding the impacts of dual methionine oxidations in complementarity-determining regions on the structure of monoclonal antibodies
Published 2024-12-01“…In this study, we used hydrogen deuterium exchange mass spectrometry (HDX-MS) and homology modeling to investigate the effects of dual methionine oxidations (heavy chain (HC) Met111 and Met115) within a single CDR on the structure of a mAb. …”
Get full text
Article -
810
Optimization of Enzymatic Hydrolysis Process of Morchella esculenta and Analysis of Volatile Flavor Compounds in Enzymatic Hydrolysate
Published 2025-02-01“…To optimize the enzymatic hydrolysis process of Morchella esculenta and expore the volatile flavor compounds in its enzymatic hydrolysate, the enzymatic hydrolysis was optimized by response surface design, and the key flavor compounds were identified by headspace-solid phase microextraction-gas chromatography-mass spectrometry (HS-SPME-GC-MS) combined with the odor activity value (OAV). …”
Get full text
Article -
811
Identification of Oligopeptides in the Distillates from Various Rounds of Soy Sauce-Flavored Baijiu and Their Effect on the Ester–Acid–Alcohol Profile in Baijiu
Published 2025-01-01“…Liquid chromatography–tandem mass spectrometry (LC-MS) was employed to identify endogenous peptides in the distillates from the first to seventh rounds of soy sauce-flavored Baijiu. …”
Get full text
Article -
812
Orthogonal Design Study on Factors Affecting the Determination of Common Odors in Water Samples by Headspace Solid-Phase Microextraction Coupled to GC/MS
Published 2013-01-01“…These two odorants have extremely low odor threshold concentrations at ng L−1 level in the water, so a simple and sensitive method for the analysis of such trace levels was developed by headspace solid-phase microextraction coupled to gas chromatography/mass spectrometry. In this study, the orthogonal experiment design L32 (49) was applied to arrange and optimize experimental conditions. …”
Get full text
Article -
813
Structural basis for the interaction between the Drosophila RTK Sevenless (dROS1) and the GPCR BOSS
Published 2025-01-01“…We further narrowed down the interacting binding epitopes on both dROS1 and BOSS using hydrogen-deuterium exchange mass spectrometry (HDX-MS). This includes beta-strands in dROS1’s third Fibronectin type III (FNIII) domain and a C-terminal peptide in BOSS’ ECR. …”
Get full text
Article -
814
Fecal metabolomics reveals the positive effect of ethanol extract of propolis on T2DM mice
Published 2023-01-01“…However, there are have only been a few reports that are based on an ultra-high performance liquid chromatography-quadrupole-time-of-flight-mass spectrometry (UPLC-Q-TOF-MS) analysis of the fecal metabolomics of ethanol extract of propolis (EEP) in the treatment of T2DM. …”
Get full text
Article -
815
Functional Characterization of Sesquiterpene Synthase from Polygonum minus
Published 2014-01-01“…Gas chromatography-mass spectrometry analysis of the transgenic plants showed that PmSTS was responsible for the production of β-sesquiphellandrene.…”
Get full text
Article -
816
Repellency Potential, Chemical Constituents of Ocimum Plant Essential Oils, and Their Headspace Volatiles against Anopheles gambiae s. s., Malaria Vector
Published 2023-01-01“…The repellency potential and chemical composition of the plants were achieved by using the protected arm-in-cage method and gas chromatography-mass spectrometry (GC-MS) analysis. Among the three Ocimum species, both the essential oils and the headspace volatiles from O. tenuiflorum achieved the longest repellency time lengths of 90–120 minutes. …”
Get full text
Article -
817
Metabolites Profiling of Manilkara mabokeensis Aubrév Bark and Investigation of Biological Activities
Published 2022-01-01“…Interestingly, gas chromatography-flame ionization detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS) analysis were enabled to identify 23 compounds in the essential oil of M. mabokeensis Aubrév bark, which have not been previously described in the literature. …”
Get full text
Article -
818
Urea enhances the yield and quality of bio-oil produced from corncob through pyrolysis
Published 2025-01-01“…Fourier Transform-Infrared Spectroscopy, Gas Chromatography-Mass Spectrometry (GC–MS), Ultimate Analysis, and High Heating Value (HHV) analyses were employed to evaluate the quality of bio-oil produced. …”
Get full text
Article -
819
Phytochemical composition and antioxidant properties of Canarium odontophyllum (Sarawak Olive): A seasonal fruit from Borneo, East Malaysia
Published 2025-02-01“…The phytochemical composition was determined by Liquid Chromatography Mass Spectrometry Quadrupole Time of Flight (LCMS-QTOF). …”
Get full text
Article -
820
Role of toxic and essential elements in sleep duration of patients with cardiovascular diseases
Published 2025-01-01“…Serum concentrations of zinc (Zn), copper (Cu), Iron (Fe), arsenic (As), mercury (Hg), and nickel (Ni) were measured using a gas chromatography-mass spectrometry. The prevalence of short-sleep duration (< 7 h), normal sleep duration (7–8 h), and long-sleep duration (> 8 h) were 36%, 10.6%, and 53.3%, respectively. …”
Get full text
Article