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  1. 4181

    Case report: A severe myositis mimicking bulbar palsy after administration of immune checkpoint inhibitors by Philippe Rochigneux, Philippe Rochigneux, Alexandre Bertucci, Elika Loir, Alexia Mattei, Danielle Robert, Michael Dassa, Brice Chanez, Mikael Ebbo, Lea Gaigne, Anne Sophie Chretien, Giovanni Corazza, Giovanni Corazza, Nicolas Schleinitz

    Published 2025-02-01
    “…In a multidisciplinary setting, she was treated with IV corticosteroids (methylprednisolone 1 mg/kg started at day 10, with a progressive decrease until 1 mg of prednisone in March 2024), IV immunoglobulins started at day 18 (1.5 g/kg in 2 days, administered monthly, with a progressive decrease and a cessation in June 2022), enteral nutrition, speech therapy and physical therapy, with noticeable improvement. …”
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  2. 4182

    Effectiveness of the ARTHE-e app for exercise adherence in people with knee osteoarthritis: protocol for a randomised controlled trial by Bruno Pereira, Charlotte Lanhers, Emmanuel Coudeyre, Lech Dobija, Mathilde Pelletier-Visa, Alexis Bonhomme

    Published 2025-01-01
    “…The primary outcome will be the difference between groups in the evolution of the EARS score at 6 months.Ethics and dissemination The study has been approved by the medical ethics committee (Comité de Protection des Personnes) XI of Saint Germain en Laye (27 March 2024) (ID for ethics approval: 24.00330.000201). …”
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  3. 4183

    A study of impulsivity and adverse childhood experiences in a population health setting by Robert W. Read, Karen A. Schlauch, Gai Elhanan, Iva Neveux, Stephanie Koning, Takesha Cooper, Takesha Cooper, Joseph J. Grzymski, Joseph J. Grzymski

    Published 2024-12-01
    “…We conducted a retrospective cohort study involving adult participants who completed the Behavioral and Mental Health Self-Assessment (HDSA) between September 2018 and March 2024. Impulsivity levels were measured using the BIS-15, and retrospective self-reports of ACEs were collected through a standardized questionnaire. …”
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  4. 4184

    Efficacy and Safety of an Aflibercept Treat-and-Extend Regimen in Treatment-Naïve Patients with Macular Oedema Secondary to Central Retinal Vein Occlusion (CRVO): A Prospective 12-... by Jose Garcia-Arumi, Francisco Gómez-Ulla, Navea Amparo, Enrique Cervera, Alex Fonollosa, Luis Arias, Javier Araiz, Juan Donate, Marta Suárez de Figueroa, Lucia Manzanas, Jaume Crespí, Roberto Gallego

    Published 2018-01-01
    “…Treatment-naïve patients with <6 month diagnosis of MO secondary to CRVO and best-corrected visual acuity (BCVA) of 73-24 ETDRS letters were included between 23 January 2015 and 17 March 2016. Intervention. Intravitreal aflibercept 2 mg monthly (3 months) followed by proactive individualized dosing. …”
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  5. 4185

    Screening and Profiling the Antioxidant Properties of Psychrophilic Microalgae and Cyanobacteria from the Baltic Sea by Vyacheslav F. Dolganyuk, Stanislav A. Sukhikh, Egor V. Kashirskih, Elena V. Ulrikh, Olga E. Kremleva, Olga O. Babich

    Published 2024-07-01
    “…The research featured psychrophilic microalgae and cyanobacteria obtained from the Curonian Lagoon and the Baltic Bay in the Baltic Sea, Kaliningrad Region, Russia, in March – May 2022. The authors used the Pasteur method and the flow cytometry method to isolate pure cultures of psychrophilic microalgae and cyanobacteria. …”
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  6. 4186

    Learnings from COVID-19 Forced Lockdown on Regional Air Quality and Mitigation Potential for South Asia by Abhishek Upadhyay, Parth Sarathi Mahapatra, Praveen Kumar Singh, Sishir Dahal, Suresh Pokhrel, Amit Bhujel, Indu Bikram Joshi, Shankar Prasad Paudel, Siva Praveen Puppala, Bhupesh Adhikary

    Published 2022-03-01
    “…In this context the country lockdown initiated to combat the COVID-19 pandemic (during March and April 2020 that is the pre-monsoon season) provides an unique opportunity for studying the relative impacts of different emission sources in the region. …”
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  7. 4187

    Long time-series and high-frequency ecological evaluation of Henan section of the Yellow River by Jianzhong Guo, Daozhu Xu, Jian Xu, Ruoxin Zhu, Ning Li

    Published 2025-01-01
    “…In terms of monthly ecological environment quality, the ranking from best to worst was May, September, October, November, December, January, August, April, July, March, June, and February, exhibiting a pattern of ‘double peaks’ and ‘double valleys’. …”
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  8. 4188

    Estimation of Total Suspended Solids Concentration in Streams Using Regression and Artificial Neural Networks Methods by Betül Mete, Sinan Nacar, Adem Bayram, Osman Tuğrul Bak

    Published 2023-01-01
    “…The data were obtained within the scope of sampling studies carried out 40 times between June 2019 and March 2020 at eight monitoring stations selected in the Sera Stream Watershed (Trabzon). …”
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  9. 4189

    Delivery, maternal and neonatal outcomes in nulliparous women with gestational diabetes undergoing epidural labour analgesia: a propensity score-matched analysis by Yu Chen, Xin Ye, Han Wu, Yanqing Chen, Huanghui Wu, Xueling Yuan, Xiaofang Yu, Xiaodan Wu

    Published 2022-07-01
    “…Objective This study aimed to retrospectively analyse the influence of epidural labour analgesia (ELA) on delivery and maternal and neonatal outcomes in nulliparous women with gestational diabetes mellitus (GDM) using propensity score-matched analysis.Design Retrospective cohort analysis.Setting Primary care practices in a teaching hospital from March 2018 to October 2021.Participants A total of 816 delivery records of nulliparous women with GDM were collected and retrospectively analysed.Interventions ELA and non-ELA (NELA) cohorts were assessed.Main outcome measure The primary outcome assessed was delivery type (spontaneous, assisted vaginal or caesarean). …”
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  10. 4190

    Multi-omics approaches to deciphering complex pathological mechanisms of migraine: a systematic review by Jiaojiao Liu, Qiaosheng Ren, Boxuan Du, Xian Liu, Yuqiu An, Peichi Zhang, Lexi Li, Zhenhong Liu, Zhenhong Liu, Kegang Cao, Kegang Cao

    Published 2025-01-01
    “…Our search encompassed multiple databases including PubMed, EMBASE, the Web of Science Core Collection, the Cochrane Library, China National Knowledge Infrastructure, the Chinese Science and Technology Periodical Database, the Wanfang database, and the China Biology Medicine Database to cover studies from database inception until 20 March 2024., The scope of our review included various aspects of migraine such as ictal and interictal phases; episodic or chronic migraine; menstrual-related migraine; and migraine with or without aura (PROSPERO registration number: CRD42024470268).ResultsA total of 38 studies were ultimately included, highlighting a range of genetic variations, transcriptional abnormalities, protein function alterations, and disruptions in metabolic pathways associated with migraine.These multi-omics findings underscore the pivotal roles played by mitochondrial dysfunction, inflammatory responses, and oxidative stress in the pathophysiology of migraine.ConclusionMulti-omics approaches provide novel perspectives and tools for comprehending the intricate pathophysiology of migraine, facilitating the identification of potential biomarkers and therapeutic targets.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/display_record.php?…”
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  11. 4191
  12. 4192

    Thyroid nodule rupture after thermal ablation for benign thyroid nodules: incidence, risk factors, and clinical management by Yu-tong Liu, Ying Wei, Zhen-Long Zhao, Jie Wu, Shi-Liang Cao, Na Yu, Yan Li, Li-Li Peng, Ming-an Yu

    Published 2025-12-01
    “…Background Thyroid nodule rupture (TNR) is a rare and severe complication after thermal ablation (TA), mostly from benign thyroid nodules (BTN).Objective To summarize the incidence of TNR after TA and analyze the causes and prevention strategies.Materials and methods This retrospective study enrolled 3971 patients who underwent TA for BTN from January 2014 to March 2024. The incidence, causes, and risk factors of TNR were analyzed. …”
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  13. 4193

    Insular infraorbital neurovascular pedicle labial salivary gland transplantation for the treatment of severe dry eye disease: an IDEAL stage 0, 1 and 2a study by Jing Zhou, Xiaohong Chen, Mei Li, Ke Yang, Ying Jie, Yinghui Wang, Yingshi Piao, Yun Cheng

    Published 2025-01-01
    “…We designed a modified LSGT, called insular infraorbital neurovascular pedicle LSGT, and evaluated the postoperative efficacy.Design This is a prospective, single-centre, self-contained study.Setting The research was conducted at Beijing Tongren Hospital, Capital Medical University from July 2019 to March 2024.Participants Eight patients (nine eyes) with severe dry eye disease (DED) were enrolled in this study.Interventions All patients underwent insular infraorbital neurovascular pedicle LSGT and were followed up for at least 6 months postoperatively.Main outcome measure Key evaluation indices were best-corrected visual acuity (BCVA), Ocular Surface Disease Index (OSDI) score, tear break-up time (TBUT), Corneal Fluorescence Staining (CFS) score, and Schirmer I test (SIT).Results With a mean follow-up of 17.56±11.72 months, BCVA improved in four eyes and stabilized in five. …”
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  14. 4194

    Entomological Investigations, Seasonal Fluctuations and Impact of Bioclimate Factors of Phlebotomines Sand Flies (Diptera: Psychodidae) of an Emerging Focus of Cutaneous Leishmania... by Fatima Zahra Talbi, Abdelhakim El Ouali Lalami, Mouhcine Fadil, Mohamed Najy, Hassan Ech-Chafay, Mohamed Lachhab, Said Lotfi, Nordine Nouayti, Khadija Lahouiti, Chafika Faraj, Abdellatif Janati Idrissi

    Published 2020-01-01
    “…During the period between November and March, the sand flies were absent. The highest prevalence of sand flies was recorded in June when the temperature and relative humidity values reached, respectively, 25.8°C and 42%. …”
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  15. 4195
  16. 4196

    A suite of wildlife crossing structures facilitates mammal movement across tropical forest fragments in a city by Li Si Tay, Ruisheng Choo, Max D. Y. Khoo, Eunice Kong, Yi Xiang Chan, Wivian H. Y. Neo, Sebastian Ow, Yuet Hsin Toh, Han Ling, Malcolm C. K. Soh, Benjamin P. Y.‐H. Lee, Adrian H. B. Loo, Kenneth B. H. Er

    Published 2024-12-01
    “…Using camera traps and closed‐circuit televisions, we documented 1133 independent crossing events across a 9‐month study period from March to November 2021. Fourteen mammal species were detected across all crossing types, with wild boar (Sus scrofa) being the most prevalent species (68.2%). …”
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  17. 4197

    Analysis of the growth trajectories of junior residents in Japan: a longitudinal cohort study using data from a nationwide e-portfolio system (EPOC2) by Sachiko Ohde, Takahiro Kiuchi, Makoto Takahashi, MASANAGA YAMAWAKI, Tsuguya Fukui, Tsuyoshi Okuhara, Hiroko Okada, Nobutoshi Nawa, Eriko Okada, Ayako Kashimada, Yu Akaishi, Yujiro Tanaka

    Published 2025-01-01
    “…The study objective is to identify the learning trajectory of junior residents to provide insights into the provision of better postgraduate and undergraduate medical education in Japan.Design Longitudinal cohort study.Setting Hospitals nationwide adopting EPOC2.Participants 7671 residents who participated in clinical training programmes at hospitals adopting EPOC2 between April 2020 and March 2022.Primary outcome measure Formative evaluation scores assessed through self-evaluation by junior residents and evaluations by supervisors/senior physicians at the end of each rotation in each clinical department.Results For all evaluation items, growth trajectories were divided into six groups, each with distinct characteristics based on the specific content of the evaluation form. …”
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  18. 4198

    Clinical application of 3D slicer reconstruction and 3D printing localization combined with neuroendoscopy technology in VPS surgery by Long Zhou, Pan Lei, Ping Song, Zhiyang Li, Huikai Zhang, Hangyu Wei, Lun Gao, Qiuwei Hua, Hui Ye, Qianxue Chen, Silei Zhang, Qiang Cai

    Published 2025-01-01
    “…Retrospective analysis of clinical data of patients with hydrocephalus treated by ventriculoperitoneal shunt surgery using 3D Slicer reconstruction and 3D printing positioning technology combined with transcranial neuroendoscopy in our hospital from October 2021 to March 2023. A total of 33 patients with complete data were collected, including 19 males and 14 females, aged 10–81 years. …”
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  19. 4199

    Analysis of Risk Factors of Gastric Low-Grade Intraepithelial Neoplasia in Asymptomatic Subjects Undergoing Physical Examination by Yingling Liu, Yuli Cai, Si Chen, Yawen Gou, Qiaomin Wang, Mingli Zhang, Yetao Wang, Haiou Hong, Kaiguang Zhang

    Published 2020-01-01
    “…A total of 3437 subjects were included in this study, and 2259 asymptomatic subjects were investigated from March 2015 to April 2018. Risk factors were evaluated, and the endoscopic features of LGIN and prognosis were described. …”
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  20. 4200

    Postoperative Harris Hip Score Versus Harris Hip Score Difference in Hip Replacement: What to Report? by Nikolai Ramadanov, Maximilian Voss, Robert Hable, Hassan Tarek Hakam, Robert Prill, Mikhail Salzmann, Dobromir Dimitrov, Roland Becker

    Published 2025-01-01
    “…Methods PubMed, CNKI, and Epistemonikos were searched until March 1, 2024. The risk of bias, level of evidence, and publication bias were assessed. …”
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