Clinical course, management and outcomes of COVID-19 in HIV-infected renal transplant recipients: A case series by L Bertels, K Manning, A Redd, T du Toit, Z Barday, E Muller

“…Among 39 HIV‐positive‐to‐HIV‐positive transplant recipients, 11 cases of COVID‐19 were diagnosed from March 2020 to September 2022. Six patients (55%) required hospitalisation, of whom 3 were admitted to a high‐care unit or intensive care unit. …”
Get full text

Risk factors for new vertebral fractures after percutaneous vertebroplasty or percutaneous kyphoplasty in the treatment of osteoporotic vertebral compression fractures by Wencheng Yang, Kaiwei Zou, Xuping Lin, Yanfang Yang, Tianpei Chen, Xiuming Wu, Xiaomeng Wang, Qingjun Liu, Chunhui Huang, Wanhan Su

“…ObjectThis study aims to conduct a prospective analysis of patients with osteoporotic vertebral compression fractures (OVCF) who underwent percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP), and further analyze the risk factors for new vertebral fracture following treatment.MethodsA prospective study was conducted from November 2020 to March 2022 at the First Hospital of Longyan City to select patients with OVCF who underwent treatment in the Department of Spinal Surgery. …”
Get full text

Path model explaining the association between fear of falling and health-related quality of life in (pre-)frail older adults by Tjard Sattler, Sophie Gottschalk, Hans-Helmut König, Tobias Braun, Gisela Büchele, Michael Denkinger, Tim Fleiner, Corinna Nerz, Kilian Rapp, Martina Schäufele, Christian Werner, Judith Dams

“…Trial registration German Clinical Trials Register, ID: DRKS00024638, https://drks.de/search/en/trial/DRKS00024638 , date of registration: March 11th 2021.…”
Get full text

Using Laboratory Test Results for Surveillance During a New Outbreak of Acute Hepatitis in 3-Week- to 5-Year-Old Children in the United Kingdom, the Netherlands, Ireland, and Curaç... by Maaike C Swets, Steven R Kerr, Brian MacKenna, Louis Fisher, Merel van Wijnen, Diederik Brandwagt, Paul W Schenk, Pieter Fraaij, Leonardus G Visser, Sebastian Bacon, Amir Mehrkar, Alistair Nichol, Patrick Twomey, Philippa C Matthews, Malcolm G Semple, Geert H Groeneveld, Ben Goldacre, Iain Jones, J Kenneth Baillie

“… Abstract BackgroundIn March 2022, a concerning rise in cases of unexplained pediatric hepatitis was reported in multiple countries. …”
Get full text

Obstructive sleep apnea and structural and functional brain alterations: a brain-wide investigation from clinical association to genetic causality by Kang Wu, Qiming Gan, Yuhong Pi, Yanjuan Wu, Wenjin Zou, Xiaofen Su, Sun Zhang, Xinni Wang, Xinchun Li, Nuofu Zhang

“…Additionally, large-scale Mendelian randomization analyses were performed using genome-wide association study (GWAS) data on OSA and 3935 brain imaging-derived phenotypes (IDPs), assessed in up to 33,224 individuals between December 2023 and March 2024, to explore potential genetic causality between OSA and alterations in whole brain structure and function. …”
Get full text

Previous treatment decreases efficacy of pralsetinib in RET fusion-positive non-small-cell lung cancer by Lei Wang, Yafei You, Wenzhuo He, Yu Hou, Lan Li, Li Wang, Chang Jiang, Jiahong Yi, Yaoxiong Xia, Liangping Xia

“…However, the efficacy and safety of pralsetinib in real world has rarely been reported.Materials and methodsThis study reviewed the efficacy and safety of pralsetinib in RET fusion-positive NSCLC patients between March 2021 and December 2021. Progression-free survival (PFS) and overall survival (OS) were evaluated by a Kaplan-Meier analysis and log-rank test. …”
Get full text

Multispecies pasture diet and cow breed affect the functional lipid profile of milk across lactation in a spring-calving dairy system by Renata Kostovska, Gaetan Drouin, Joaquín J. Salas, Mónica Venegas-Calerón, Brendan Horan, John T. Tobin, Tom F. O'Callaghan, Sean A. Hogan, Alan L. Kelly, Laura G. Gómez-Mascaraque

“…In addition to the 2 pasture diets, the study uniquely examined the combined effects of breed, namely Holstein Friesian (HF) or Jersey Holstein Friesian (JFX), and lactation stage in Ireland, spanning from March to November. Bulk milk samples (n = 144 yearly) for the 4 groups examined were collected for 4 wk per each of the 9 mo specified. …”
Get full text

Systematic review of multidrug-resistant Klebsiella pneumoniae in the Arabian Peninsula: molecular epidemiology and resistance patterns by Enaam K. Idrees, Enaam K. Idrees, Marwh G. Aldriwesh, Marwh G. Aldriwesh, Marwh G. Aldriwesh, Manal M. Alkhulaifi, Majed F. Alghoribi, Majed F. Alghoribi, Majed F. Alghoribi

“…This systematic review aims to analyze the emergence of antimicrobial resistance genes in MDR K. pneumoniae across GHC countries.MethodsA systematic search was conducted using PubMed, ScienceDirect, and OpenMD for articles published up to March 15, 2023. The search strategy focused on the bacterial name, drug-resistance genotypes, and GHC countries. …”
Get full text

Sex-related association between smoke exposure and gallstones in a US population: a cross-sectional study by Xingyong Huang, Xuanyu Hao, Tingting Wang, Xiaoyue Zhang, Peng Wu, Lufan Shen, Yuanyuan Yang, Wanchuan Zhang, Kai Zhang

“…Methods We conducted a cross-sectional analysis using data obtained from the National Health and Nutrition Examination Survey from 2017 to March 2020. The analysis was limited to individuals aged ≥ 20 years with complete information available. …”
Get full text

Pan-tumor analysis to investigate the obesity paradox in immune checkpoint blockade by Evan J Lipson, Ludmila Danilova, Elizabeth M Jaffee, Won Jin Ho, Mark Yarchoan, Yasser Ged, Jean Hoffman-Censits, Jennifer Durham, Sanjay Bansal, Chester Kao, Rajat Mohindra, Stephanie L Alden, Tanguy Y Seiwert, Soren Charmsaz, Howard L Li, Kabeer Munjal, Hua-Ling Tsai, Alexei Hernandez, Erin M Coyne, Rachel Garonce-Hediger, Laura Tang, Marina Baretti, Kathryn Howe, G Scott Chandler, Madelena Brancati, Aanika Warner, Ervin Griffin, Mari Nakazawa, Chris Thoburn, Jennifer Gizzi, Nicole E Gross, Elsa Hallab, Sarah S Shin, Aditi Guha

“…To interrogate mechanisms of divergent immune responses in obese and non-obese patients, we examined the relationship among obesity status, clinical responses, and immune profiles from a diverse, pan-tumor cohort of patients treated with ICI-based therapy.Methods From June 2021 to March 2023, we prospectively collected serial peripheral blood samples from patients with advanced or metastatic solid tumors who received ICI as standard of care at Johns Hopkins. …”
Get full text

Sacubitril/valsartan in patients with heart failure with reduced ejection fraction with end‐stage of renal disease by Seonhwa Lee, Jaewon Oh, Hyoeun Kim, Jaehyung Ha, Kyeong‐hyeon Chun, Chan Joo Lee, Sungha Park, Sang‐Hak Lee, Seok‐Min Kang

“…Methods and results We retrospectively analysed the clinical and laboratory data of 501 HFrEF patients who administered with SV from March 2017 to April 2019 in a single tertiary university hospital. …”
Get full text

A qualitative study of stigma in patients with low anterior resection syndrome of rectal cancer (直肠癌低位前切除综合征患者病耻感的质性研究) by WEN Ruizhen (温瑞珍), CHEN Piao (陈飘), LI Yalan (李亚兰), CAO Aifang (曹爱芳), WANG Miaolan (王淼兰), ZHENG XiaoXuan (郑筱暄), PENG Hui (彭慧)

“…Methods Purposive sampling method was used to select the patients with LARS symptoms after rectal surgery of a Class Ⅲ Grade A hospital in Guangzhou from March 2024 to May 2024 as subjects. The descriptive qualitative study was used to conduct face-to-face semi-constructive interviews with patients, and the recording materials were processed by Nvivo12. 0 software. …”
Get full text

Clonal hematopoiesis of indeterminate potential is a risk factor of gastric cancer: A Prospective Cohort in UK Biobank study by Zhihui Xi, Huolun Feng, Kunling Chen, Xin Guo, Dandan Zhu, Jiabin Zheng, Yong Li

“…Design: This cohort study used data from the UK Biobank collected from baseline (2006–2010) to the end of follow-up in March 2024. Setting: Data on age, sex, race, alcohol consumption, smoking status and type 2 diabetes were collected at baseline interview. …”
Get full text

Identification of patient demographic, clinical, and SARS-CoV-2 genomic factors associated with severe COVID-19 using supervised machine learning: a retrospective multicenter study by Kuganya Nirmalarajah, Patryk Aftanas, Shiva Barati, Emily Chien, Gloria Crowl, Amna Faheem, Lubna Farooqi, Alainna J. Jamal, Saman Khan, Jonathon D. Kotwa, Angel X. Li, Mohammad Mozafarihashjin, Jalees A. Nasir, Altynay Shigayeva, Winfield Yim, Lily Yip, Xi Zoe Zhong, Kevin Katz, Robert Kozak, Andrew G. McArthur, Nick Daneman, Finlay Maguire, Allison J. McGeer, Venkata R. Duvvuri, Samira Mubareka

“…Methods A cohort of adult patients with laboratory confirmed SARS-CoV-2 from 11 participating healthcare institutions in the Greater Toronto Area (GTA) were recruited from March 2020 to April 2022. Supervised machine learning (ML) models were developed to predict hospitalization using SARS-CoV-2 lineage-specific genomic signatures, patient demographics, symptoms, and pre-existing comorbidities. …”
Get full text

HIV self-testing positivity rate and linkage to confirmatory testing and care: a telephone survey in Côte d’Ivoire, Mali, and Senegal by Kra, Arsène Kouassi, Fotso, Arlette Simo, Rouveau, Nicolas, Maheu-Giroux, Mathieu, Boily, Marie-Claude, Silhol, Romain, d’Elbée, Marc, Vautier, Anthony, Larmarange, Joseph

“…Initially, participants were recruited via leaflets from March to June and completed a sociobehavioural questionnaire. …”
Get full text

Heart disease in pregnancy and adverse outcomes: an umbrella review by Jiani Zhang, Jiani Zhang, Yuxin Ren, Yuxin Ren, Bingjie Li, Qi Cao, Qi Cao, Xiaodong Wang, Xiaodong Wang, Haiyan Yu, Haiyan Yu

“…BackgroundHeart disease in pregnancy encompasses both congenital heart disease and maternal-acquired heart disease, both of which are associated with an increased risk of various adverse outcomes for mothers and their offspring.ObjectiveThe objective of the study was to review and summarize the evidence regarding the association between heart disease in pregnancy and adverse outcomes in mothers and their offspring.Data sourcesA comprehensive search was conducted in Embase, PubMed, Web of Science, and the Cochrane Database of Systematic Reviews from inception to March 2024. The protocol for this review was registered in PROSPERO (CRD42024519144).Study eligibility criteriaThis review included systematic reviews and meta-analyses that examined the association between heart disease in pregnancy and adverse outcomes for mothers and their offspring.Study appraisal and synthesis methodsData were independently extracted by two reviewers. …”
Get full text

Human health risk assessment of drinking water using heavy metal pollution index: a GIS-based investigation in mega city by Maria Latif, Iqra Nasim, Mubeen Ahmad, Rab Nawaz, Arifa Tahir, Muhammad Atif Irshad, Aamal A. Al-Mutairi, Ali Irfan, Sami A. Al-Hussain, Magdi E. A. Zaki

“…A total of 25 samples were collected by random sampling from hand pumps during 4 months (March–June, 2021) for determining various physiochemical attributes (pH, electric conductivity, turbidity, total hardness, chloride, and phosphate) and potentially toxic elements (arsenic, cadmium, and lead) using standard protocols. …”
Get full text

Mid- to long-term clinical outcomes of modified technique skip-level titanium plate fixation in cervical laminoplasty compared to continuous fixation by Shuo Feng, QiRui Zhu, Yang Sun, ZiYao Ding, Zhe Zhuang, Heng-Heng Yu, Ma-Ji Sun, Feng Yuan

“…Methods A retrospective analysis of 125 patients (62 men, 63 women, average age 60.9 ± 10.4 years) with multilevel cervical spondylotic myelopathy who had cervical laminoplasty with Arch titanium plate fixation from January 2012 to March 2024 in our hospital was done. Patients were stratified into two cohorts based on the fixation technique: Group A (n = 64): Modified technique of skip-level titanium plate fixation (Arch titanium plates at C4 and C6 levels combined with adjacent spinous process suture suspension)Group B (n = 61): Continuous plating (Arch titanium plates applied sequentially from C3 to C7).The comparative analysis focused on perioperative parameters (operative duration, intraoperative blood loss, length of hospital stay), economic factors (hospital costs), and various clinical indicators. …”
Get full text

Clinical characteristics and outcomes of surgical resection for brain metastases from lung adenocarcinoma by Ming Li, Zhiying Li, Hang Zhang, Hiroaki Wakimoto, Linlin Sun, Tiantian Wang, Shengli Zhou, Liyun Zhou

“…ObjectiveThe purpose of this study was to explore the clinical characteristics, survival time and prognostic factors of patients undergoing craniotomy for brain metastases (BM) from lung adenocarcinoma (LUAD).MethodsA total of 208 patients with BM from LUAD who underwent craniotomy at the Zhengzhou University People’s Hospital, Henan province, China from March 2005 to October 2022 were included in this retrospective study. …”
Get full text

Faktor Risiko Terjadinya Ulkus Diabetikum pada Pasien Diabetes Mellitus yang Dirawat Jalan dan Inap di RSUP Dr. M. Djamil dan RSI Ibnu Sina Padang by Rizky Loviana Roza, Rudy Afriant, Zulkarnain Edward

“…Djamil and RSI Ibnu Sina Padang from January until March 2014. The result from the analyze data from 6 variable known gender (p =0,595; OR=0,654), duration of DM (p=1,000; OR = 1,158), neuropathy (p=0,411; OR=1,833), PAD (p=0,004; OR= 5,5), trauma (p=0,02; OR= 4), and foot care (p=1,000; OR=1,158). …”
Get full text