Informing policy with health labour market analysis to improve availability of family doctors in Tajikistan by Jamoliddin Abdullozoda, Salomudin Yusufi, Sulakshana Nandi, Parvina Makhmudova, Juana Paola Bustamante, Margrieta Langins, Alba Llop-Gironés, Ilker Dastan, Victor Olsavszky, Shukhrat Sultonov, Zebo Najmuddinova, Natasha Azzopardi-Muscat, Tomas Zapata

“…Implementation of the Action Plan will require political commitment, financial resources, strong inter-sectoral collaboration, stakeholder management, and cross-country learning of best practices. …”
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Efficacy of carbonyl cyanide-3-chlorophenylhydrazone in combination with antibiotics against Mycobacterium abscessus by Jifang Zheng, Qiang Liu, Haoran Wang, Fengmin Huo, Junnan Jia, Hairong Huang, Suting Chen

“…ABSTRACT Given the intrinsic resistance of Mycobacterium abscessus to a wide range of conventional antibiotics, it is urgent to explore new therapeutic approaches to manage this infection effectively. Carbonyl cyanide 3-chlorophenylhydrazone (CCCP), a proton pump inhibitor, has shown good bacteriostatic activity against M. abscessus. …”
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From Clinical Trial Evidence to Clinical Guidelines: Perspectives on REWIND from Clinicians in the Gulf and Levant Region by Talal Ashour, Sami Azar, Akram Echtay, Muhammad Farooqi, Tarek Fiad, Mohamed Hassanein, Ahmed Hassoun, Abdul Jabbar, Amin Jayyousi, Kari Ranta, Hani Sabbour, Fatih Tangi, Ibrahim Turfanda

“…Utilizing published data and author opinion, this review explores the importance of taking a cardiocentric approach to T2D management, and discusses the clinical implications of REWIND for people with T2D in the Gulf and Levant region. …”
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Spatiotemporal evolution of landscape ecological risk and its driving factors of the Beijing–Tianjin–Hebei major mineral belt, 1985–2022 by Yilin Wang, Xiaohong Wang, Wei Zhang, Weidong Man, Mingyue Liu, Linlin Jiao

“…The findings of the research project provide a scientific rationale and reference for future land use, resource optimization, landscape ecological risk differential management and ecological restoration. Furthermore, the findings are of considerable importance in terms of maintaining ecological security patterns.…”
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Casual associations between frailty and nine mental disorders: bidirectional Mendelian randomisation study by Yong Zhou, Jiayue Duan, Jiayi Zhu, Yunying Huang, Tao Tu, Keke Wu, Qiuzhen Lin, Yingxu Ma, Qiming Liu

“…Understanding these associations is crucial for the effective management of frailty and improvement of mental disorders. …”
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Global regional and national burden of intracerebral hemorrhage between 1990 and 2021 by Zhao-wei Wang, Mei-ping Wan, Jia-hui Tai, Yong Wang, Min-yi Yin

“…This suggests improvements in prevention and management strategies over time. However, the burden of ICH remains substantial and unevenly distributed across regions, with lower SDI areas facing a disproportionately higher burden. …”
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Impact of the severity and extension of dental caries lesions on Turkish preschool children’s oral health-related quality of life: a cross-sectional study by Ayça Kurt, Damla Bolat, Ömer Hatipoğlu

“…Early detection and management of dental caries are crucial in improving the quality of life for affected individuals. …”
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A common mechanism of detoxification for lambda-cyhalothrin and abamectin in Cydia pomonella by Di Ju, Chao Hu, Peirong Li, Ping Gao, Yuting Li, Xueqing Yang

“…Therefore, it is crucial to comprehend the commonalities in these mechanisms to effectively develop strategies for managing resistance. Materials and methods To determine whether target-site insensitivity to LCT and AM plays a role in resistance, the sequences of voltage-gated sodium channel (VGSC) and glutamate-gated chloride channel (GluCl) containing the mutation domains were detected. …”
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Novel prehospital lactate cut-off estimation for mortality: a multicentre observational study by Ancor Sanz-García, Carlos del Pozo Vegas, Daniel Zalama-Sánchez, Raúl López-Izquierdo, Francisco Martín-Rodríguez, Pedro Ángel de Santos Castro, Eduardo Silva Alvarado, Santos Gracia Villar, Luis Alonso Dzul López, Silvia Aparicio Obregón, Rubén Calderon Iglesias

“…Considering this cut-off point could improve patient management via EMS services, allowing quick identification of patients at high risk of clinical worsening.Trial registration number ISRCTN Registry (ISRCTN17676798, ISRCTN48326533, ISRCTN49321933).…”
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Clinical characteristics and outcomes of patients with chondroblastoma undergoing surgery with various adjuvant procedures: a retrospective study of 59 cases by Toru Hirozane, Tetsuya Sekita, Eisuke Kobayashi, Tomoaki Mori, Naofumi Asano, Toru Udaka, Takashi Tajima, Rumi Nakagawa, Kazutaka Kikuta, Akira Yoshiyama, Hideo Morioka, Itsuo Watanabe, Ukei Anazawa, Michiro Susa, Keisuke Horiuchi, Yoshihisa Suzuki, Takeshi Morii, Robert Nakayama

“…If bone grafts are necessary, materials with low biocompatibility, including artificial bone, may be optimal. Managing patients with chondroblastoma should encompass curative and functional aspects.…”
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Age-stratified analysis of the BMI-kidney stone relationship: findings from a national cross-sectional study by Liuliu Zhou, Wei Gu, Yufeng Jiang, Haimin Zhang

“…The relationship between BMI and kidney stones is non-linear, highlighting the need to develop age-specific BMI management strategies to reduce the occurrence of kidney stones.…”
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Ecosystem carbon stock variation along forest stand ages: insight from eastern coast mangrove ecosystem of India by Muktipada Panda, Bikash R. Dash, Sudam C. Sahu

“…Understanding the carbon stock dynamics along the age of forest stands in the mangrove forest ecosystem is of significance for managing the forests and their carbon accumulation. …”
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Prevalence and clinical profile of comorbidity among newly diagnosed pulmonary tuberculosis patients: a multi-center observational study in eastern China by Wei Wang, Wei Wang, Xiaomeng Wang, Xiaomeng Wang, Songhua Chen, Jun Li, Qinglin Cheng, Yu Zhang, Qian Wu, Qian Wu, Kui Liu, Kui Liu, Xuli Jiang, Bin Chen, Bin Chen

“…Thus, integration of screening and personalized management is needed for the control of tuberculosis and its comorbidities.…”
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Therapeutic Potential of Ginger Ethanolic Extract, Ginger-Loaded Chitosan ‎Nanoparticles, and Chitosan Nanoparticles in Induced Type 2 Diabetes Mellitus in Dogss in Induced Type 2... by Rasema M Hameed, Alaa K Mahmood

“…Further investigations with larger cohorts and longer durations are ‎recommended to confirm these results and ascertain the clinical applicability and safety of ‎these natural remedies in managing canine diabetes‎‎‎.       …”
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The performance of upper arm circumference for age in diagnosing severe acute malnutrition in children aged 6 to 59 months in South Kivu, Eastern Democratic Republic of Congo: Lwir... by Gaylord Ngaboyeka, Armand Mulume, Emmanuel Lurhangire, Anouk Neven, Lydia Zigabe, Serge Balolebwami, Pacifique Mwene-Batu, Michelle Dramaix, Philippe Donnen, Ghislain Bisimwa

“…Methods We analyzed a database of children admitted from 1987 to 2008 for management of SAM in the east of the DRC. Anthropometric indicators (z-score) were calculated and classified according to the standards of the World Health Organization (WHO). …”
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Clinical usefulness of patient-reported-outcome-measurement information system in Pediatric Crohn’s Disease: a cross-sectional study by Sara Azevedo, Maria Miguel Oliveira, Paulo Nogueira, Ana Isabel Lopes

“…The meaningful associations with clinical assessment and treatment efficacy reinforce the clinical relevance and utility of PROs in the patient-centered management of pediatric IBD and highlight the importance of self-reports as a gold standard tool for assessing health status.…”
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Using CT imaging to identify sarcopenia as a risk factor for severe falls in older adults by Nadja Fries, Angeliki Kotti, Mischa Woisetschläger, Anna Spångeus

“…Conclusions These results underscore the importance of addressing sarcopenia and related risk factors, including malnutrition, in the management and prevention of severe falls in the elderly population. …”
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A mobile-based multidomain lifestyle intervention using Cognitive Evergreenland for older adults with subjective cognitive decline: a feasibility study by Rong Lin, Yuanjiao Yan, Zhili Chen, Chenshan Huang, Junyu Zhao, Mingfeng Chen, Hong Li

“…Throughout the 24 weeks of the prescribed intervention, app usage remained consistently high, with over 92% of participants using the mini-program at least once a week and successfully completing corresponding health management tasks. In terms of average usage, cognitive training emerged as the most frequently used functional module (95.73%), closely followed by health education (95.02%). …”
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Multi-omics uncovers immune-modulatory molecules in plasma contributing to resistance exercise-ameliorated locomotor disability after incomplete spinal cord injury by Ren Zhou, Jibao Chen, Yunhan Tang, Chuijin Wei, Ping Yu, Xinmei Ding, Li’ao Zhu, Jiajia Yao, Zengqiang Ouyang, Jing Qiao, Shumin Xiong, Liaoliao Dong, Tong Yin, Haiqing Li, Ye Feng, Lin Cheng

“…However, to optimize clinical management and mimic exercise-like effects, it is imperative to obtain a comprehensive understanding of the molecular alterations that underlie these positive effects. …”
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Effect of a perinatal care quality improvement package on patient satisfaction: a secondary outcome analysis of a cluster-randomised controlled trial by Ashish KC, Anna Bergstrom, Mats Målqvist, Dipak Chaulagain, Olivia Brunell

“…The final analysis included 54 919 women.Intervention Hospital management was engaged and facilitators were recruited from within hospitals. …”
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