Clinical Predictors of Aspirin Resistance in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis by Fan Zhang, Hongyan Zheng

“…AR was predominantly linked to specific laboratory parameters, particularly those indicative of heightened insulin resistance and inadequate lipid management. Specifically, the laboratory parameters associated with AR included fasting glucose level (mean difference (MD) = 8.21; 95% confidence interval (CI) = 2.55 to 13.88), glycated hemoglobin (MD = 0.22; 95% CI = 0.06 to 0.38), high-density lipoprotein (HDL) level (MD = –2.02; 95% CI = –3.62 to –0.42), low-density lipoprotein (LDL) level (MD = 7.00; 95% CI = 2.87 to 11.13), total cholesterol level (MD = 9.52; 95% CI = 4.37 to 14.67), and triglyceride levels (MD = 12.51; 95% CI = 3.47 to 21.55). …”
Get full text

Artificial Neural Network and Response Surface Methodology-Driven Optimization of Cu–Al₂O₃/Water Hybrid Nanofluid Flow in a Wavy Enclosure with Inclined Perio... by Tarikul Islam, Sílvio Gama, Marco Martins Afonso

“…The waviness of the geometry shows a significant impact on thermal management as well. Moreover, the statistical RSM analysis indicates a high <i>R</i>² value of 98.88% for the response function, which suggests that the model is well suited for predicting <i>Nu</i>_av. …”
Get full text

MHRA-MS-3D-ResNet-BiLSTM: A Multi-Head-Residual Attention-Based Multi-Stream Deep Learning Model for Soybean Yield Prediction in the U.S. Using Multi-Source Remote Sensing Data by Mahdiyeh Fathi, Reza Shah-Hosseini, Armin Moghimi, Hossein Arefi

“…Accurate prediction of soybean yield is important for safeguarding food security and improving agricultural management. Recent advances have highlighted the effectiveness and ability of Machine Learning (ML) models in analyzing Remote Sensing (RS) data for this purpose. …”
Get full text

Shiftwork and insulin resistance in professional drivers: exploring the association using non-insulin-based surrogate measures by Mirella Youssef Tawfik, Shaimaa A. A. M. Amer, Ahmed Mahmoud Fouad

“…Insomnia and poor meal timing habits significantly increases the odds of insulin resistance among professional drivers, suggesting interventions targeting sleep quality, meal timing, and stress management.…”
Get full text

COVID-19 is a risk factor for retinal vein occlusion in younger patients? by A.G. Shchuko, M.V. Akulenko, T.N. Yur’eva

“…Some authors report on clinical presentations typical for RVOs in the COVID-19 infection due to hypercoagulation. Management of younger patients with RVO required a complex diagnostic approach to assess systemic risk factors and obligatory evaluation of baseline retinal ischemia using fluorescein angiography (FA) or optical coherence tomography angiography (OCTA). …”
Get full text

Dynamic stability evaluation method of mine goaf slopes by Yan DU, Hongda ZHANG, Mowen XIE, Yujing JIANG, Ming ZHANG, Beining JIA

“…This improved method offers a more accurate assessment of mine slope stability by considering goaf settlement and locking section damage, providing a valuable tool for managing similar geological disasters.…”
Get full text

Status of cerebrovascular autoregulation relates to outcome in severe paediatric head injury: STARSHIP, a prospective multicentre validation studyResearch in context by Shruti Agrawal, Claudia Smith, Stefan Y. Bogli, Michal M. Placek, Manuel Cabeleira, Deborah White, Esther Daubney, Adam Young, Erta Beqiri, Riaz Kayani, Diarmuid O'Donnell, Nazima Pathan, Suzanna Watson, Anna Maw, Matthew Ganrett, Hari Krishan Kanthimathianathan, Harish Bangalore, Santosh Sundararajan, Gayathri Subramanian, Dusan Raffaj, Avishay Sarfatti, Simona Lampareillo, Anton Mayer, Oliver Ross, Marek Czosnyka, Peter J. Hutchinson, Peter Smielewski, Carly Tooke, Caroline Payne, Holly Belfield, Amisha Mistry, Collette Spencer, Claire Jennings, Lara Bunni, Laura Anderson, Emily Morgan, Melanie James, Rebecca Beckley, Tahnima Khatun, Hafiza Khatun, Olivia Nugent, Richard Aldridge, Ruth Morgan, Julie Morcombe, Martin Quinton, Catherine Postlethwaite, Jenny Pond, Jessica Cutler, Caitlin Oxford

“…Summary: Background: Continuous assessment of cerebral autoregulation (CA) using pressure reactivity index (PRx), is a promising tool for individualized management to improve outcome after traumatic brain injury (TBI). …”
Get full text

Voices from the clinic: a qualitative analysis of physiotherapy strategies in musculoskeletal care for knee osteoarthritis patients by Jennifer Nguyen, Justine M. Naylor, Sarah Dennis, Rebecca Livings, Kathryn Mills, Siobhan M. Schabrun, Jeanette M. Thom

“…The thematic analysis identified two over-arching themes; (1) capacity to deliver and awareness of evidence-based care and (2) perceived recommendations for future physiotherapy management. Participants identified notable areas of potential service improvement including developing stronger and more effective reimbursement models, increased consult times and improved patient access. …”
Get full text

Impact of Year and Genotype on Benzoxazinoids and Their Microbial Metabolites in the Rhizosphere of Early-Vigour Wheat Genotypes in Southern Australia by Paul A. Weston, Shahnaj Parvin, Pieter-W. Hendriks, Saliya Gurusinghe, Greg J. Rebetzke, Leslie A. Weston

“…We are now investigating the role of early-vigour traits, including early canopy closure and biomass accumulation upon improved competitive ability of wheat, which will eventually result in more cost-effective weed management.…”
Get full text

Exploring drug utilization patterns, healthcare resource utilization, and epidemiology of rheumatoid arthritis in Colombia: a retrospective claims database study by Daniel G. Fernández-Ávila, Monica Betancur, Amira Kronfly, Edwin Jáuregui

“…These findings emphasize the importance of tailoring RA management strategies to the local context.…”
Get full text

1990–2041 Global burden of Burkitt lymphoma with 20 years forecast: A systematic analysis using the global burden disease of study of 2021 by Chengyun Dou, Yidan Sang, Hongbo Zhu, Chuangjie Cao

“…Hopefully, this study will help optimize the prevention, diagnosis, treatment, and management of Burkitt lymphoma to reduce the disease burden.…”
Get full text

Thermoresponsive Gels with Rosemary Essential Oil: A Novel Topical Carrier for Antimicrobial Therapy and Drug Delivery Applications by Ludovic Everard Bejenaru, Adina-Elena Segneanu, Cornelia Bejenaru, Ionela Amalia Bradu, Titus Vlase, Dumitru-Daniel Herea, Marius Ciprian Văruţ, Roxana Maria Bălăşoiu, Andrei Biţă, Antonia Radu, George Dan Mogoşanu, Maria Viorica Ciocîlteu

“…By integrating the bioactive potential of RoEO with the advanced delivery capabilities of PLGA microparticles and thermoresponsive gels, this study paves the way for the development of next-generation formulations tailored to meet the specific needs of localized drug delivery in skin health management.…”
Get full text

Association between joint exposure to ambient air pollutants and carotid plaque: The mediating role of cardiometabolic risk factors by Yunfei Li, Ze Han, Xiaoyu Zhao, Yueruijing Liu, Zhiyuan Wu, Jinqi Wang, Xia Li, Xiuhua Guo, Lixin Tao

“…Methods: The Beijing Health Management Cohort (BMHC) study followed participants recruited from 2013 to 2014 until December 31, 2020. …”
Get full text

Strategies adopted by men to deal with uncertainty and anxiety when following an active surveillance/monitoring protocol for localised prostate cancer and implications for care: a... by Chris Metcalfe, Jenny Donovan, Julia Wade, Vincent J Gnanapragasam, Michael Davis, David Neal, Richard Martin, Athene Lane, Edward Rowe, Freddie Hamdy, James Catto, Emma Turner, David Gillatt, Eleanor Walsh, Derek Rosario, Tim Peters, Roger Kockelbergh, Alan Paul, Peter Holding, Howard Kynaston, Owen Hughes, Prasad Bollina, Alan Doherty, Edgar Paez

“…Trust in the clinical team was critical for men in balancing anxiety and facilitating successful management change/continued monitoring. Only men from ProtecT were included; men outside ProtecT may have different experiences.Conclusion Men looked to clinicians for clarity, control and reassurance. …”
Get full text

Cryptococcal Meningitis: A Retrospective Cohort of a Brazilian Reference Hospital in the Post-HAART Era of Universal Access by Aline Z. de Azambuja, Gustavo Wissmann Neto, Guilherme Watte, Luciana Antoniolli, Luciano Z. Goldani

“…Despite adequate antifungal treatment and management of intracranial hypertension in a reference tertiary care hospital, mortality was high. …”
Get full text

Comparative evaluation of BacT/ALERT VIRTUO and BACTEC FX400 blood culture systems for the detection of bloodstream infections by Yurong Qin, Yiwen Liao, Jingfang Zhou, Weijiang Liu, Huimin Chen, Xiaoli Chen, Weisha Wang, Ni Zhang, Yunhu Zhao, Liang Wang, Bing Gu, Suling Liu

“…These findings emphasize VIRTUO’s effectiveness in enhancing diagnostic accuracy, achieving faster time to detection, and expanding the spectrum of detected organisms, thereby facilitating the quicker initiation of appropriate therapies, supporting precise clinical decision-making, and ultimately improving patient outcomes.IMPORTANCEOur study conducted a critical evaluation of advanced blood culture technologies for managing bloodstream infections (BSI). A distinctive strength of our research is the large sample size and the concurrent testing of the same patients with two systems, a methodology rarely achieved in other studies. …”
Get full text

The Use of Coffee Cherry Pulp Extract as an Alternative to an Antibiotic Growth Promoter in Broiler Diets by Wanaporn Tapingkae, Phatchari Srinual, Pimporn Khamtavee, Naret Pintalerd, Thanongsak Chaiyaso, Mongkol Yachai, Chanidapha Kanmanee, Chompunut Lumsangkul, Orranee Srinual

“…It provides a sustainable and environmentally friendly option for supplementary feed, contributing to more efficient poultry nutrition management.…”
Get full text

Processability and Material Behavior of NiTi Shape Memory Alloys Using Wire Laser-Directed Energy Deposition (WL-DED) by Hediyeh Dabbaghi, Nasrin Taheri Andani, Mohammad Pourshams, Mahyar Sojoodi, Behrang Poorganji, Mohammad Elahinia

“…Additionally, our research highlighted important considerations for civil engineering applications, particularly in the development of seismic dampers for energy dissipation in structures, offering a promising solution for enhancing structural performance and energy management in critical infrastructure.…”
Get full text

Influence of religion and spirituality on head and neck cancer patients and their caregivers: a protocol for a scoping review by Maheeka Seneviwickrama, Ruwan Jayasinghe, Kehinde Kazeem Kanmodi, Simon N. Rogers, Su Keill, Sakuntha Ratnapreya, Sriyani Ranasinghe, Sashini Shehana Denagamagei, Irosha Perera

“…The findings of this review would generate evidence to better inform health care providers in countries and cultures in the management of patients diagnosed with HNC in usual oncological care with due consideration to caregivers.…”
Get full text

Pharmacodynamic characteristics and influencing factors of tapentadol for chronic pain relief under dose titration by Liang Xin, Haoxiang Zhu, Haoxiang Zhu, Suping Niu, Xie Han, Hongxian Pang, Jiangfan Li, Ye Hu, Xuhong Wang, Lujin Li, Lujin Li, Yi Fang

“…This model is intended to provide a pharmacodynamic reference for designing rational tapentadol dose titration schemes in clinical research.MethodsRandomized controlled trials assessing the efficacy of tapentadol in the management of chronic pain were retrieved from public databases (PubMed and EMBASE). …”
Get full text