Cervical cancer burden and attributable risk factors across different age and regions from 1990 to 2021 and future burden prediction: results from the global burden of disease stud... by Lu-yao Cheng, Ji-qi Zhao, Ting-ting Zou, Zhong-hua Xu, Yin Lv

“…More efficient targeted prevention and management strategies, easy access to health care in less developed regions, and risk factor modifications should be promoted, in order to reduce the global burden of CC.…”
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Improving Individualized Salbutamol Treatment: A Population Pharmacokinetic Model for Oral Salbutamol in Virtual Patients by Lara Marques, Nuno Vale

“…Each formulation exhibits distinct pharmacokinetic (PK) and pharmacodynamic (PD) profiles, influencing therapeutic outcomes and adverse effects. Although asthma management predominantly relies on inhaled salbutamol, understanding how these formulations interact with patient-specific characteristics could improve personalized medicine approaches, potentially uncovering the therapeutic benefits of alternative formulations for an individual patient. …”
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Synergistic Effects of Thymoquinone and Carob Powder versus Dexamethasone in the Model of Asthma in Pregnant Rats: New Insights into their Therapeutic Effects by Ameerah Fadhil Ahmed, Şule Coşkun Cevher, Emine Gülceri Güleç Peker, Barbaros Balabanlı, Meral Ebegil

“…The aim of this study was to reveal the strength of the effects of thymoquinone (TQ) and carob powder administration, which are known to have two different strong antioxidant effects during pregnancy, on the oxidative event in the mother with the diet management strategies. Methods: In this study, it was tried to improve the asthmatic pregnant rat and to determine the direction of oxidant-antioxidant balance with a holistic antioxidant complex Female rats were divided into 3 groups: asthmatic pregnant group (1) sensitized via an intraperitoneal injection of ovalbumin (OVA) with alum on days 0 and 14 and exposed to aerosolized OVA 3 days over the subsequent 1 week then coupled with male rats to get pregnant; asthmatic pregnant with TQ and carob (CS) group (2) sensitized as above then administered each of TQ and CS on the last 5 days of pregnancy; and asthmatic pregnant with dexamethasone group (3) sensitized as above then received dexamethasone by intraperitoneal injection on last 5 days of pregnancy. …”
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Circulating CD3+CD8+ T Lymphocytes as Indicators of Disease Status in Patients With Early Breast Cancer by Han‐Kun Chen, Yi‐Ling Chen, Wei‐Pang Chung, Zhu‐Jun Loh, Kuo‐Ting Lee, Hui‐Ping Hsu

“…Conclusion Circulating CD3+CD8+ CTL emerged as promising prognostic biomarkers and therapeutic targets in breast cancer management.…”
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Nitrogen and water additions with or without mowing altered soil microbial community characteristics in a semi-arid steppe by Hao Liu, Feirong Ren, Shiqiang Wan, Shijie Han, Junqiang Zheng

“…These findings enhance our understanding of soil microbial community assembly and provide a scientific basis for managing temperate grasslands, particularly in the context of global change's impact on ecosystem function and stability.…”
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The CD4/CD8 ratio is associated with T lymphocyte functions in long-term virally suppressed patients with HIV by Qing Xiao, Fengting Yu, Liting Yan, Xiaojie Lao, Xuelei Liang, Hongxin Zhao, Liuyue Zhai, Zailin Yang, Xiaomei Zhang, Yao Liu, Fujie Zhang

“…Abstract Objective Long-term management of people living with HIV (PLWHs) often relies on CD4+ T cell counts for assessing immune recovery, yet a single metric offers limited information. …”
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Patient-Reported Outcomes in Children Undergoing the Modified Green Procedure for Treating Sprengel’s Deformity: Results from a Multicentric Study by Giovanni Trisolino, Paola Zarantonello, Marco Todisco, Giovanni Luigi Di Gennaro, Grazia Chiara Menozzi, Philipp Scheider, Alessandro Depaoli, Diego Antonioli, Gino Rocca, Sebastian Farr

“…The aim of this study is to document the combined experience of two paediatric orthopaedic departments in managing SD using the modified Green Procedure, with a specific emphasis on the clinical and functional outcomes reported by patients; Methods: from June 2010 to February 2023, 42 shoulders in 40 paediatric patients were surgically treated for SD at two paediatric orthopaedic departments. …”
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Understanding hospital length of stay in trauma laparotomy patients: a National Trauma Database Study by Jeremy Grushka, Kosar Khwaja, Hayaki Uchino, Evan G Wong

“…Stratification based on HLOS revealed distinct factors associated with short and long HLOS categories, indicating that targeted interventions for each category could potentially reduce HLOS and enhance patient outcomes in the current era of constrained healthcare resources.Level of evidence, study type Level IV, therapeutic/care management.…”
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Interrelation between hypoxic liver injury and Killip classification in ST-segment elevation myocardial infarction patients by Seong Huan Choi, Ji-Hun Jang, Dae-Young Kim, Young Ju Suh, Yong-Soo Baek, Sung-Hee Shin, Seong-Ill Woo, Dae-Hyeok Kim, Jeonggeun Moon, Jon Suh, WoongChol Kang, Sang-Don Park, Sung Woo Kwon

“…Early recognition of HLI and accurate assessment of Killip classification is warranted for effective management of STEMI.…”
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An explainable Bi-LSTM model for winter wheat yield prediction by Abhasha Joshi, Biswajeet Pradhan, Subrata Chakraborty, Subrata Chakraborty, Renuganth Varatharajoo, Abdullah Alamri, Shilpa Gite, Chang-Wook Lee

“…Accurate, reliable and transparent crop yield prediction is crucial for informed decision-making by governments, farmers, and businesses regarding food security as well as agricultural business and management. Deep learning (DL) methods, particularly Long Short-Term Memory networks, have emerged as one of the most widely used architectures in yield prediction studies, providing promising results. …”
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Strategic selection of polliniser trees can improve fruit quality of lychee, a crop that exhibits mixed-mating by Stephen J. Trueman, Joel Nichols, Christopher J. Burwell, Wiebke Kämper

“…Fruit trees are often planted in single-cultivar blocks that allow convenient orchard management. This planting design can reduce the opportunities for cross-pollination, decreasing fruit quality if many harvested fruit result from selfing rather than outcrossing. …”
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Uncovering the Risks: Investigating the Impact of Abnormal 50 g Results of Two-Step Gestational Diabetes Mellitus Screening in Pregnant Women by Sakine Rahımlı Ocakoglu, Bayram Ali Dorum, Zeliha Atak, Özlem Özgün Uyanıklar, Gökhan Ocakoğlu

“…Timely identification and management of GDM can mitigate the potential for maternal and fetal complications. …”
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Transforming Non-Digital, Clinical Workflows to Detect and Track Vision-Threatening Diabetic Retinopathy via a Digital Platform Integrating Artificial Intelligence: Implementation... by Peranut Chotcomwongse, Paisan Ruamviboonsuk, Chaiwat Karavapitayakul, Koblarp Thongthong, Anyarak Amornpetchsathaporn, Methaphon Chainakul, Malee Triprachanath, Eckachai Lerdpanyawattananukul, Niracha Arjkongharn, Varis Ruamviboonsuk, Nattaporn Vongsa, Pawin Pakaymaskul, Turean Waiwaree, Hathaiphan Ruampunpong, Richa Tiwari, Viroj Tangcharoensathien

“…Abstract Introduction Screening diabetic retinopathy (DR) for timely management can reduce global blindness. Many existing DR screening programs worldwide are non-digital, standalone, and deployed with grading retinal photographs by trained personnel. …”
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Diagnostics and treatment of cardiac achalasia and cardiospasm: guidelines of the Russian gastroenterological association by V. T. Ivashkin, A. S. Trukhmanov, E. A. Godzhello, I. V. Mayev, Yu. V. Evsyutina, T. L. Lapina, O. A. Storonova

“…To present clinical guidelines of the Russian gastroenterological association on management of cardiac achalasia and cardiospasm to practical doctors. …”
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A novel hybrid methodology for wind speed and solar irradiance forecasting based on improved whale optimized regularized extreme learning machine by S. Syama, J. Ramprabhakar, R Anand, V. P. Meena, Josep M. Guerrero

“…The fast incorporation of clean energy sources, particularly solar and wind power, into the existing power grid in the last several years has raised a major problem in controlling and managing the power grid due to the intermittent nature of these sources. …”
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Up-to-Date Imaging for Parathyroid Tumor Localization in MEN1 Patients with Primary Hyperparathyroidism: When and Which Ones (A Narrative Pictorial Review) by Valentina Berti, Francesco Mungai, Paolo Lucibello, Maria Luisa Brandi, Carlo Biagini, Alessio Imperiale

“…Additionally, we will explore integrated imaging approaches that combine multiple modalities to enhance localization accuracy and optimize surgical planning—an essential component of holistic management in MEN1 cases. Various imaging techniques are employed for presurgical localization, including ultrasound (US), multiphase parathyroid computed tomography (CT) scanning (4D CT), magnetic resonance imaging (MRI), and nuclear medicine techniques like single photon emission computed tomography/CT (SPECT/CT) and positron emission tomography/CT (PET/CT). …”
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Exploring fatigue in Marfan and hypermobile Ehlers-Danlos syndromes: an analytical cross-sectional study in two Italian healthcare centres by Rosario Caruso, Alessandro Pini, Gianluca Conte, Arianna Magon, Irene Baroni, Edward Callus, Nathasha Udugampolage, Jacopo Taurino, Alessandra Bassotti, Giada De Angeli, Giulia Paglione, Giuliana Trifirò

“…Temporal fatigue patterns also differed, with a more evenly distributed pattern throughout the day in hEDS, correlating with higher insomnia scores.Conclusions The results underscore the severe impact of fatigue on individuals with hEDS compared with those with MFS, suggesting the need for targeted, multidisciplinary management strategies to enhance quality of life.Trial registration number NCT05712564.…”
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Economic impact of road accidents on costs of employee turnover: A quantitative study from Poland by Agata Małgorzata Jaździk-Osmólska, Magdalena Kalbarczyk Kalbarczyk, Daniel Trzaskowski, Robert Wojtachnik, Adrianna Trzaskowska-Dmoch

“…A decrease in the risk of death in road safety in Poland in 2014-2019 did not reduce the costs to enterprises, which grew from PLN 1.1 million to PLN 1.6 million. Management of economic loss in enterprises due to road accidents is essential not only from the financial point of the organisation but also from the idea of corrective instruments to equate marginal social costs with marginal social benefits of transport The results of the conducted research bridge the research gap, vital from the point of view of community and corporate operations, regarding the volume of losses of enterprises due to employee turnover due to road accidents, which are likely to affect any. …”
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Impact of COVID-19 vaccination on tinnitus onset and severity: a comprehensive survey study by Anusha Yellamsetty, Egbe-Etu Etu, Shaowen Bao

“…Identifying risk factors, such as underlying health conditions and psychological stress, will be crucial in developing strategies for the management and treatment of tinnitus in vaccinated individuals.…”
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Critical Discourse Analysis of the Manifestations of English Linguistic Challenges: The Case Of The New Draft Language Policy In The South African Police Services by Tebogo Johannes Kekana, Malesela Edward Montle

“…The data can also help the Language Management unit of the SAPS. …”
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